Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_M13
(779 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (E... 105 1e-22
sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich... 102 1e-21
sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich... 101 2e-21
sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4 101 2e-21
sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5... 100 6e-21
sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich... 100 6e-21
sp|Q23121|RSP1_CAEEL Probable splicing factor, arginine/ser... 99 1e-20
sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich... 93 9e-19
sp|Q23120|RSP2_CAEEL Probable splicing factor, arginine/ser... 93 9e-19
sp|Q10021|RSP5_CAEEL Probable splicing factor, arginine/ser... 81 3e-15
>sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (Enhancer of deformed) (52-kDa
bracketing protein) (B52 protein)
Length = 376
Score = 105 bits (262), Expect = 1e-22
Identities = 55/131 (41%), Positives = 76/131 (58%)
Frame = +3
Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185
R+Y+G LP + ERD+++FF+ YGR R + +KNGYGFVE +D RDA+DA+++L+G +LLG
Sbjct: 5 RVYVGGLPYGVRERDLERFFKGYGRTRDILIKNGYGFVEFEDYRDADDAVYELNGKELLG 64
Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365
ERV VE AR A P+R+E+R+I
Sbjct: 65 ERVVVEPARGTA-RGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLI 123
Query: 366 VDGLSSRVSWQ 398
V+ LSSRVSWQ
Sbjct: 124 VENLSSRVSWQ 134
Score = 65.5 bits (158), Expect = 2e-10
Identities = 30/43 (69%), Positives = 37/43 (86%)
Frame = +2
Query: 644 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYD 772
DLKD MR+ GEVT+ADAHK R+N+GVVEF++ SDMK AI+K D
Sbjct: 135 DLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLD 177
>sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich 6 (Pre-mRNA splicing factor
SRP55)
Length = 344
Score = 102 bits (254), Expect = 1e-21
Identities = 55/132 (41%), Positives = 73/132 (55%)
Frame = +3
Query: 3 PRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLL 182
PR+YIG L + E+DI++FF YGR+ VDLKNGYGFVE +D RDA+DA+++L+G +L
Sbjct: 2 PRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKELC 61
Query: 183 GERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRI 362
GERV VE AR P+R+E+R+
Sbjct: 62 GERVIVEHARG---------PRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRL 112
Query: 363 IVDGLSSRVSWQ 398
IV+ LSSR SWQ
Sbjct: 113 IVENLSSRCSWQ 124
Score = 66.2 bits (160), Expect = 9e-11
Identities = 30/44 (68%), Positives = 36/44 (81%)
Frame = +2
Query: 644 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDG 775
DLKD MR+ GEVT+ADAHK R N+GV+EF + SDMK A+DK DG
Sbjct: 125 DLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDG 168
>sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich 4 (Pre-mRNA splicing factor
SRP75) (SRP001LB)
Length = 494
Score = 101 bits (252), Expect = 2e-21
Identities = 56/132 (42%), Positives = 72/132 (54%)
Frame = +3
Query: 3 PRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLL 182
PR+YIG L + ERD+++FF+ YG+I VDLKNGYGFVE DD RDA+DA+++L+G L
Sbjct: 2 PRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLC 61
Query: 183 GERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRI 362
GERV VE AR P R+E+R+
Sbjct: 62 GERVIVEHARG---------------PRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRL 106
Query: 363 IVDGLSSRVSWQ 398
IV+ LSSR SWQ
Sbjct: 107 IVENLSSRCSWQ 118
Score = 64.3 bits (155), Expect = 4e-10
Identities = 29/44 (65%), Positives = 37/44 (84%)
Frame = +2
Query: 644 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDG 775
DLKD MR+ GEVT+ADAHK R+N+GV+EF + SDMK A++K DG
Sbjct: 119 DLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDG 162
>sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4
Length = 489
Score = 101 bits (252), Expect = 2e-21
Identities = 56/132 (42%), Positives = 72/132 (54%)
Frame = +3
Query: 3 PRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLL 182
PR+YIG L + ERD+++FF+ YG+I VDLKNGYGFVE DD RDA+DA+++L+G L
Sbjct: 2 PRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLC 61
Query: 183 GERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRI 362
GERV VE AR P R+E+R+
Sbjct: 62 GERVIVEHARG---------------PRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRL 106
Query: 363 IVDGLSSRVSWQ 398
IV+ LSSR SWQ
Sbjct: 107 IVENLSSRCSWQ 118
Score = 64.3 bits (155), Expect = 4e-10
Identities = 29/44 (65%), Positives = 37/44 (84%)
Frame = +2
Query: 644 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDG 775
DLKD MR+ GEVT+ADAHK R+N+GV+EF + SDMK A++K DG
Sbjct: 119 DLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDG 162
>sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Insulin-induced growth response protein CL-4)
(Delayed-early protein HRS)
Length = 269
Score = 100 bits (248), Expect = 6e-21
Identities = 52/131 (39%), Positives = 75/131 (57%)
Frame = +3
Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185
R++IG L E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365
ERVT+E AR+ + P+R+E+R+I
Sbjct: 65 ERVTIEHARARS-------------RGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLI 111
Query: 366 VDGLSSRVSWQ 398
V+ LSSRVSWQ
Sbjct: 112 VENLSSRVSWQ 122
Score = 59.7 bits (143), Expect = 9e-09
Identities = 27/44 (61%), Positives = 35/44 (79%)
Frame = +2
Query: 644 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDG 775
DLKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K G
Sbjct: 123 DLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSG 166
>sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Delayed-early protein HRS)
Length = 272
Score = 100 bits (248), Expect = 6e-21
Identities = 52/131 (39%), Positives = 75/131 (57%)
Frame = +3
Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185
R++IG L E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365
ERVT+E AR+ + P+R+E+R+I
Sbjct: 65 ERVTIEHARARS-------------RGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLI 111
Query: 366 VDGLSSRVSWQ 398
V+ LSSRVSWQ
Sbjct: 112 VENLSSRVSWQ 122
Score = 59.7 bits (143), Expect = 9e-09
Identities = 27/44 (61%), Positives = 35/44 (79%)
Frame = +2
Query: 644 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDKYDG 775
DLKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K G
Sbjct: 123 DLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSG 166
>sp|Q23121|RSP1_CAEEL Probable splicing factor, arginine/serine-rich 1 (RNA-binding
protein srp-5) (CeSRp75)
Length = 312
Score = 99.0 bits (245), Expect = 1e-20
Identities = 54/140 (38%), Positives = 73/140 (52%), Gaps = 9/140 (6%)
Frame = +3
Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185
R+YIG L R+ E+DI+ FFR YG+IR V LKNG+GFVE DD+RDAEDA+HDL+G +L G
Sbjct: 4 RIYIGRLTSRVSEKDIEHFFRGYGQIRDVLLKNGFGFVEFDDKRDAEDAVHDLNGKELGG 63
Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIR------ 347
ERV ++ ++ P R
Sbjct: 64 ERVILDYSKPRGGGGDRGGFGGGGRGGARVSSYSGGGGGGRDRFDRYDRGPPRRESRYGR 123
Query: 348 ---SEHRIIVDGLSSRVSWQ 398
+ HR++V+ LSSR+SWQ
Sbjct: 124 PYSTRHRVVVENLSSRISWQ 143
>sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Delayed-early protein HRS)
Length = 270
Score = 92.8 bits (229), Expect = 9e-19
Identities = 49/131 (37%), Positives = 72/131 (54%)
Frame = +3
Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185
R++IG L E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365
ERVT+E AR+ + ++ +R+I
Sbjct: 65 ERVTIEHARARS-------------RGGRGRGRYSDRLAVADLGNDRRKCSTCKNRNRLI 111
Query: 366 VDGLSSRVSWQ 398
V+ LSSRVSWQ
Sbjct: 112 VENLSSRVSWQ 122
Score = 57.8 bits (138), Expect = 3e-08
Identities = 26/41 (63%), Positives = 34/41 (82%)
Frame = +2
Query: 644 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSDMKAAIDK 766
DLKD MR+ GEVTFADAH+ + N+GVVEF++ D+K AI+K
Sbjct: 123 DLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEK 163
>sp|Q23120|RSP2_CAEEL Probable splicing factor, arginine/serine-rich 2 (RNA-binding
protein srp-4) (CeSRp40)
Length = 281
Score = 92.8 bits (229), Expect = 9e-19
Identities = 47/131 (35%), Positives = 68/131 (51%)
Frame = +3
Query: 6 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 185
R+YIG LP R +RD++ FFR YG++ V +KNG+GFV+ D+RDA+DA+HDL+G +L G
Sbjct: 3 RVYIGRLPNRASDRDVEHFFRGYGKLSDVIMKNGFGFVDFQDQRDADDAVHDLNGKELCG 62
Query: 186 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 365
ERV +E R +P + R++
Sbjct: 63 ERVILEFPRRKV-------GYNEERSGSGFRGREPTFRKGGERQFSNRYSRPCSTRFRLV 115
Query: 366 VDGLSSRVSWQ 398
+D LS+R SWQ
Sbjct: 116 IDNLSTRYSWQ 126
>sp|Q10021|RSP5_CAEEL Probable splicing factor, arginine/serine-rich 5 (RNA-binding
protein srp-3) (CeSC35-2)
Length = 208
Score = 81.3 bits (199), Expect = 3e-15
Identities = 36/72 (50%), Positives = 51/72 (70%), Gaps = 2/72 (2%)
Frame = +3
Query: 3 PRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLL 182
PRLY+G +P ERD+++F + YG+I ++ +K G+ FV+ +D RDAEDA HDLDG +
Sbjct: 2 PRLYLGKIPYNARERDVERFLKGYGKINNISMKYGFAFVDFEDSRDAEDACHDLDGKTME 61
Query: 183 GE--RVTVEMAR 212
G R+ VEMAR
Sbjct: 62 GSSMRLVVEMAR 73
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,606,006
Number of Sequences: 369166
Number of extensions: 1557898
Number of successful extensions: 3643
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3319
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3564
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7308943600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)