Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_L04
(591 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9GP32|ALF_ECHMU Fructose-bisphosphate aldolase 250 2e-66
sp|P53442|ALF_SCHMA Fructose-bisphosphate aldolase 248 6e-66
sp|P53445|ALF1_LAMJA Fructose-bisphosphate aldolase, muscle... 207 2e-53
sp|P53448|ALDOC_CARAU Fructose-bisphosphate aldolase C (Bra... 207 2e-53
sp|P00883|ALDOA_RABIT Fructose-bisphosphate aldolase A (Mus... 205 6e-53
sp|P05064|ALDOA_MOUSE Fructose-bisphosphate aldolase A (Mus... 205 8e-53
sp|P05065|ALDOA_RAT Fructose-bisphosphate aldolase A (Muscl... 204 1e-52
sp|P04075|ALDOA_HUMAN Fructose-bisphosphate aldolase A (Mus... 204 2e-52
sp|P09117|ALDOC_RAT Fructose-bisphosphate aldolase C (Brain... 202 7e-52
sp|P46563|ALF2_CAEEL Fructose-bisphosphate aldolase 2 (Aldo... 201 9e-52
>sp|Q9GP32|ALF_ECHMU Fructose-bisphosphate aldolase
Length = 363
Score = 250 bits (638), Expect = 2e-66
Identities = 124/159 (77%), Positives = 137/159 (86%)
Frame = +2
Query: 2 VTEEVLSYVYKGLADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPA 181
VTE+VLS+VYK LADHHVYLEGTLLKPNMVT GQSCT KY++E NA ATV+ALQRTVP A
Sbjct: 205 VTEQVLSFVYKALADHHVYLEGTLLKPNMVTCGQSCTKKYSVEDNARATVEALQRTVPVA 264
Query: 182 VAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAA 361
V GV FLSGGQSE DAT NLNAINKY G+KPW L+FSFGRALQAS + AW+GK ENVKA
Sbjct: 265 VPGVVFLSGGQSELDATRNLNAINKYPGKKPWALSFSFGRALQASAIAAWQGKPENVKAG 324
Query: 362 QDQLLHLASANGAAAVGKFDGNLKTAAGGKSLFVANHAY 478
Q + L LA ANGAA++GKF+G LKTAAG KSLFVANHAY
Sbjct: 325 QAEFLQLAKANGAASLGKFEGELKTAAGQKSLFVANHAY 363
>sp|P53442|ALF_SCHMA Fructose-bisphosphate aldolase
Length = 363
Score = 248 bits (634), Expect = 6e-66
Identities = 124/159 (77%), Positives = 136/159 (85%)
Frame = +2
Query: 2 VTEEVLSYVYKGLADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPA 181
VTE+VL++VYK LADHHVYLEGTLLKPNMVTAGQ+C YT ++NA ATV+ALQRTVPPA
Sbjct: 205 VTEQVLAFVYKALADHHVYLEGTLLKPNMVTAGQACKKAYTPQENALATVRALQRTVPPA 264
Query: 182 VAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAA 361
V G+TFLSGGQSE DAT NLN INK G KPW LTFSFGRALQASVL WKGKKENV AA
Sbjct: 265 VPGITFLSGGQSELDATKNLNEINKIPGPKPWALTFSFGRALQASVLATWKGKKENVHAA 324
Query: 362 QDQLLHLASANGAAAVGKFDGNLKTAAGGKSLFVANHAY 478
Q++LL LA ANGAAAVGKF+GN+ T G KSLFVANHAY
Sbjct: 325 QEELLKLAKANGAAAVGKFEGNMGTTLGDKSLFVANHAY 363
>sp|P53445|ALF1_LAMJA Fructose-bisphosphate aldolase, muscle type
Length = 363
Score = 207 bits (527), Expect = 2e-53
Identities = 105/159 (66%), Positives = 124/159 (77%)
Frame = +2
Query: 2 VTEEVLSYVYKGLADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPA 181
+TE+VL+ YK L+DHHVYLEGTLLKPNMVT G + EQ A AT+ AL+RTVPPA
Sbjct: 205 ITEKVLAATYKALSDHHVYLEGTLLKPNMVTVGTAAPASTRPEQVAMATLTALRRTVPPA 264
Query: 182 VAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAA 361
V G+TFLSGGQSE DA+I+LNAINK H KPW LTFS+GRALQASVL+AW GKKEN+KAA
Sbjct: 265 VPGITFLSGGQSEEDASIHLNAINKLHLIKPWALTFSYGRALQASVLKAWGGKKENLKAA 324
Query: 362 QDQLLHLASANGAAAVGKFDGNLKTAAGGKSLFVANHAY 478
QD+L+ A NG A+ G++ AA G+SLFVANHAY
Sbjct: 325 QDELMRRAKINGQASKGEYKPTGTGAAAGESLFVANHAY 363
>sp|P53448|ALDOC_CARAU Fructose-bisphosphate aldolase C (Brain-type aldolase)
Length = 363
Score = 207 bits (527), Expect = 2e-53
Identities = 105/159 (66%), Positives = 124/159 (77%)
Frame = +2
Query: 2 VTEEVLSYVYKGLADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPA 181
VTE+VL+ YK L+DHHVYLEGTLLKPNMVTAG SC TK++ ++ A ATV AL+RTVPPA
Sbjct: 205 VTEKVLAACYKALSDHHVYLEGTLLKPNMVTAGHSCPTKFSNQEIAMATVTALRRTVPPA 264
Query: 182 VAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAA 361
V GVTFLSGGQSE +A+INLNAIN KPW LTFS+GRALQAS L AW+G KEN KAA
Sbjct: 265 VTGVTFLSGGQSEEEASINLNAINNCPLTKPWALTFSYGRALQASALSAWRGVKENEKAA 324
Query: 362 QDQLLHLASANGAAAVGKFDGNLKTAAGGKSLFVANHAY 478
++ L A ANG AA GK+ + + G+SL+VANHAY
Sbjct: 325 TEEFLKRAEANGLAAQGKYVSSGMDGSAGQSLYVANHAY 363
>sp|P00883|ALDOA_RABIT Fructose-bisphosphate aldolase A (Muscle-type aldolase)
Length = 364
Score = 205 bits (522), Expect = 6e-53
Identities = 105/160 (65%), Positives = 127/160 (79%), Gaps = 1/160 (0%)
Frame = +2
Query: 2 VTEEVLSYVYKGLADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPA 181
VTE+VL+ VYK L+DHH+YLEGTLLKPNMVT G +CT KY+ E+ A ATV AL+RTVPPA
Sbjct: 205 VTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKYSHEEIAMATVTALRRTVPPA 264
Query: 182 VAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAA 361
V GVTFLSGGQSE +A+INLNAINK KPW LTFS+GRALQAS L+AW GKKEN+KAA
Sbjct: 265 VTGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAA 324
Query: 362 QDQLLHLASANGAAAVGKFDGNLKT-AAGGKSLFVANHAY 478
Q++ + A AN A GK+ + + AA +SLF++NHAY
Sbjct: 325 QEEYVKRALANSLACQGKYTPSGQAGAAASESLFISNHAY 364
>sp|P05064|ALDOA_MOUSE Fructose-bisphosphate aldolase A (Muscle-type aldolase) (Aldolase
1)
Length = 364
Score = 205 bits (521), Expect = 8e-53
Identities = 105/160 (65%), Positives = 128/160 (80%), Gaps = 1/160 (0%)
Frame = +2
Query: 2 VTEEVLSYVYKGLADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPA 181
VTE+VL+ VYK L+DHHVYLEGTLLKPNMVT G +CT K++ E+ A ATV AL+RTVPPA
Sbjct: 205 VTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACTQKFSNEEIAMATVTALRRTVPPA 264
Query: 182 VAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAA 361
V GVTFLSGGQSE +A+INLNAINK KPW LTFS+GRALQAS L+AW GKKEN+KAA
Sbjct: 265 VTGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAA 324
Query: 362 QDQLLHLASANGAAAVGKFDGNLKT-AAGGKSLFVANHAY 478
Q++ + A AN A GK+ + ++ AA +SLF++NHAY
Sbjct: 325 QEEYIKRALANSLACQGKYTPSGQSGAAASESLFISNHAY 364
>sp|P05065|ALDOA_RAT Fructose-bisphosphate aldolase A (Muscle-type aldolase)
Length = 364
Score = 204 bits (520), Expect = 1e-52
Identities = 105/160 (65%), Positives = 128/160 (80%), Gaps = 1/160 (0%)
Frame = +2
Query: 2 VTEEVLSYVYKGLADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPA 181
VTE+VL+ VYK L+DHHVYLEGTLLKPNMVT G +CT K++ E+ A ATV AL+RTVPPA
Sbjct: 205 VTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACTQKFSNEEIAMATVTALRRTVPPA 264
Query: 182 VAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAA 361
V GVTFLSGGQSE +A+INLNAINK KPW LTFS+GRALQAS L+AW GKKEN+KAA
Sbjct: 265 VPGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAA 324
Query: 362 QDQLLHLASANGAAAVGKFDGNLKT-AAGGKSLFVANHAY 478
Q++ + A AN A GK+ + ++ AA +SLF++NHAY
Sbjct: 325 QEEYIKRALANSLACQGKYTPSGQSGAAASESLFISNHAY 364
>sp|P04075|ALDOA_HUMAN Fructose-bisphosphate aldolase A (Muscle-type aldolase) (Lung
cancer antigen NY-LU-1)
Length = 364
Score = 204 bits (518), Expect = 2e-52
Identities = 104/160 (65%), Positives = 127/160 (79%), Gaps = 1/160 (0%)
Frame = +2
Query: 2 VTEEVLSYVYKGLADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPA 181
VTE+VL+ VYK L+DHH+YLEGTLLKPNMVT G +CT K++ E+ A ATV AL+RTVPPA
Sbjct: 205 VTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPA 264
Query: 182 VAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAA 361
V G+TFLSGGQSE +A+INLNAINK KPW LTFS+GRALQAS L+AW GKKEN+KAA
Sbjct: 265 VTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAA 324
Query: 362 QDQLLHLASANGAAAVGKFDGNLKT-AAGGKSLFVANHAY 478
Q++ + A AN A GK+ + + AA +SLFV+NHAY
Sbjct: 325 QEEYVKRALANSLACQGKYTPSGQAGAAASESLFVSNHAY 364
>sp|P09117|ALDOC_RAT Fructose-bisphosphate aldolase C (Brain-type aldolase)
Length = 363
Score = 202 bits (513), Expect = 7e-52
Identities = 99/159 (62%), Positives = 124/159 (77%)
Frame = +2
Query: 2 VTEEVLSYVYKGLADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPA 181
VTE+VL+ VYK L+DHHVYLEGTLLKPNMVT G +C KY+ E+ A ATV AL+RTVPPA
Sbjct: 205 VTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACPIKYSPEEIAMATVTALRRTVPPA 264
Query: 182 VAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAA 361
V GVTFLSGGQSE +A++NLNAIN+ +PW LTFS+GRALQAS L AW+G+++N AA
Sbjct: 265 VPGVTFLSGGQSEEEASLNLNAINRCSLPRPWALTFSYGRALQASALSAWRGQRDNAGAA 324
Query: 362 QDQLLHLASANGAAAVGKFDGNLKTAAGGKSLFVANHAY 478
++ + A NG AA GK++G+ A +SL+VANHAY
Sbjct: 325 TEEFIKRAEMNGLAAQGKYEGSGDGGAAAQSLYVANHAY 363
>sp|P46563|ALF2_CAEEL Fructose-bisphosphate aldolase 2 (Aldolase CE-2) (CE2)
Length = 366
Score = 201 bits (512), Expect = 9e-52
Identities = 104/159 (65%), Positives = 120/159 (75%)
Frame = +2
Query: 2 VTEEVLSYVYKGLADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPA 181
VTE+VL++VYK LADHHVYLEGTLLKPNMVT GQS +K + E ATV AL+R VP A
Sbjct: 208 VTEQVLAFVYKALADHHVYLEGTLLKPNMVTPGQSSASKASHEAIGLATVTALRRGVPAA 267
Query: 182 VAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAA 361
V G+TFLSGGQSE DAT NLNAIN KPW LTFS+GRALQASVL+AW GK EN+ AA
Sbjct: 268 VPGITFLSGGQSELDATANLNAINSVQLGKPWKLTFSYGRALQASVLKAWGGKDENIAAA 327
Query: 362 QDQLLHLASANGAAAVGKFDGNLKTAAGGKSLFVANHAY 478
Q LLH + ANG A++GK+ G A +SLFVA H+Y
Sbjct: 328 QKTLLHRSKANGDASLGKYAGEDAAGAAAESLFVAKHSY 366
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,452,391
Number of Sequences: 369166
Number of extensions: 1528287
Number of successful extensions: 4028
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3890
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3995
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4455160255
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)