Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_K16
(585 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q62422|OSTF1_MOUSE Osteoclast-stimulating factor 1 (SH3 ... 172 6e-43
sp|Q92882|OSTF1_HUMAN Osteoclast-stimulating factor 1 166 3e-41
sp|Q6UB98|ANR12_HUMAN Ankyrin repeat domain protein 12 (Ank... 88 2e-17
sp|Q6UB99|ANR11_HUMAN Ankyrin repeat domain protein 11 (Ank... 85 2e-16
sp|Q9H2K2|TNKS2_HUMAN Tankyrase 2 (TANK2) (Tankyrase II) (T... 77 2e-14
sp|O95271|TNKS1_HUMAN Tankyrase 1 (TANK1) (Tankyrase I) (TN... 76 5e-14
sp|Q80YE7|DAPK1_MOUSE Death-associated protein kinase 1 (DA... 76 5e-14
sp|P16157|ANK1_HUMAN Ankyrin-1 (Erythrocyte ankyrin) (Ankyr... 75 2e-13
sp|P53355|DAPK1_HUMAN Death-associated protein kinase 1 (DA... 72 1e-12
sp|Q02357|ANK1_MOUSE Ankyrin-1 (Erythrocyte ankyrin) 72 1e-12
>sp|Q62422|OSTF1_MOUSE Osteoclast-stimulating factor 1 (SH3 domain protein 3)
Length = 215
Score = 172 bits (436), Expect = 6e-43
Identities = 86/179 (48%), Positives = 119/179 (66%), Gaps = 6/179 (3%)
Frame = +3
Query: 3 LLYIFDMISSPDWWRARANGKEGLVPSNYVSQQTESIENPMHEAAKRGNLEFLLECLSNK 182
++YI DM S WW+ G+ GL+PSNYV++Q ESI+NP+HEAAKRGNL +L ECL N+
Sbjct: 38 IIYITDM-SDTSWWKGTCKGRTGLIPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNR 96
Query: 183 VSVNGLDNAGCTPLHWAAFGGHYDCAKLLI-DTKCQVDIKNKLGETPLHNASLKGHAVLV 359
V VNGLD AG T L+WA GGH D ++L +++ +NKLG+T LH A+ KG+A +V
Sbjct: 97 VGVNGLDKAGSTALYWACHGGHKDIVEVLFTQPNVELNQQNKLGDTALHAAAWKGYADIV 156
Query: 360 ELLLKSGANANALNNDKETPYKLARNPECAALLRSAD-----SNFKPNFENYVDEEDSD 521
+LLL GA + NN+K+ +A N CA+LL+ + N E+Y+D+EDSD
Sbjct: 157 QLLLAKGARTDLRNNEKKLALDMATNAACASLLKKKQQGTDGARTLSNAEDYLDDEDSD 215
>sp|Q92882|OSTF1_HUMAN Osteoclast-stimulating factor 1
Length = 214
Score = 166 bits (421), Expect = 3e-41
Identities = 83/178 (46%), Positives = 118/178 (66%), Gaps = 5/178 (2%)
Frame = +3
Query: 3 LLYIFDMISSPDWWRARANGKEGLVPSNYVSQQTESIENPMHEAAKRGNLEFLLECLSNK 182
++YI DM S +WW+ + G+ GL+PSNYV++Q ESI+NP+HEAAKRGNL +L ECL N+
Sbjct: 38 IIYITDM-SDTNWWKGTSKGRTGLIPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNR 96
Query: 183 VSVNGLDNAGCTPLHWAAFGGHYDCAKLLI-DTKCQVDIKNKLGETPLHNASLKGHAVLV 359
V VNGLD AG T L+WA GGH D ++L +++ +NKLG+T A+ KG+A +V
Sbjct: 97 VGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIELNQQNKLGDTAFDAAAWKGYADIV 156
Query: 360 ELLLKSGANANALNNDKETPYKLARNPECAALLRSADS----NFKPNFENYVDEEDSD 521
+LLL GA + N +K+ + +A N CA+LL+ N E+Y+D+EDSD
Sbjct: 157 QLLLAKGARTDLRNIEKKLAFDMATNAACASLLKKKQGTDAVRTLSNAEDYLDDEDSD 214
>sp|Q6UB98|ANR12_HUMAN Ankyrin repeat domain protein 12 (Ankyrin repeat-containing
cofactor 2) (GAC-1 protein)
Length = 2062
Score = 87.8 bits (216), Expect = 2e-17
Identities = 52/143 (36%), Positives = 80/143 (55%)
Frame = +3
Query: 90 VSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLL 269
V+++ E E P+H AA RG+++ + E +S +VN D AG TPLH A G+YD AK+L
Sbjct: 178 VNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKIL 237
Query: 270 IDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLARNPECA 449
I V+ + +TPLH+++ GH +V+LLL+ G N N E P +A E
Sbjct: 238 IAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELE 297
Query: 450 ALLRSADSNFKPNFENYVDEEDS 518
LL+ + + E+Y D E++
Sbjct: 298 LLLK-REVPLSDDDESYTDSEEA 319
Score = 37.7 bits (86), Expect = 0.021
Identities = 21/53 (39%), Positives = 31/53 (58%)
Frame = +3
Query: 279 KCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLARN 437
K +V+ +N+ GETPLH A+++G V+ L+ GAN N + TP A N
Sbjct: 175 KDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACN 227
>sp|Q6UB99|ANR11_HUMAN Ankyrin repeat domain protein 11 (Ankyrin repeat-containing
cofactor 1)
Length = 2664
Score = 84.7 bits (208), Expect = 2e-16
Identities = 49/123 (39%), Positives = 68/123 (55%)
Frame = +3
Query: 90 VSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLL 269
V+++ E E +H AA RG+ + E +S VN D AG T LH A G+YD AK L
Sbjct: 162 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQL 221
Query: 270 IDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLARNPECA 449
+ +V+ K +TPLH+A+ GH +V+LLL+ G N N ETP K+A +P
Sbjct: 222 LAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMV 281
Query: 450 ALL 458
LL
Sbjct: 282 NLL 284
Score = 45.8 bits (107), Expect = 8e-05
Identities = 31/86 (36%), Positives = 41/86 (47%)
Frame = +3
Query: 180 KVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIKNKLGETPLHNASLKGHAVLV 359
K VN + G T LH AA G K LI V++K+ G T LH A +G+ +
Sbjct: 159 KDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVA 218
Query: 360 ELLLKSGANANALNNDKETPYKLARN 437
+ LL +GA N D +TP A N
Sbjct: 219 KQLLAAGAEVNTKGLDDDTPLHDAAN 244
Score = 35.4 bits (80), Expect = 0.11
Identities = 16/39 (41%), Positives = 27/39 (69%)
Frame = +3
Query: 276 TKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANAN 392
TK +V+ +N+ GET LH A+++G A ++ L+ GA+ N
Sbjct: 158 TKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVN 196
>sp|Q9H2K2|TNKS2_HUMAN Tankyrase 2 (TANK2) (Tankyrase II) (TNKS-2) (TRF1-interacting
ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like
protein) (Tankyrase-related protein)
Length = 1166
Score = 77.4 bits (189), Expect = 2e-14
Identities = 55/149 (36%), Positives = 70/149 (46%), Gaps = 7/149 (4%)
Frame = +3
Query: 78 PSNYVSQQTESIEN-PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYD 254
P N + T+ + P+H AA NLE L + VN D G PLH AA GH D
Sbjct: 667 PDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVD 726
Query: 255 CAKLLIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLAR 434
A LLI V+ +K TPLH A+ KG L LLL GA+ N + +TP L
Sbjct: 727 VAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVS 786
Query: 435 NPECAALLRSA------DSNFKPNFENYV 503
+ +ALL +A S +KP N V
Sbjct: 787 ADDVSALLTAAMPPSALPSCYKPQVLNGV 815
Score = 64.7 bits (156), Expect = 2e-10
Identities = 36/106 (33%), Positives = 54/106 (50%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H AA + + L + V+ D G PLH A GHY+ A+LL+ V++
Sbjct: 529 PLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVA 588
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLARN 437
+ TPLH A+ KG + +LLL+ GA+ N D TP L ++
Sbjct: 589 DLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKD 634
Score = 58.9 bits (141), Expect = 9e-09
Identities = 41/133 (30%), Positives = 62/133 (46%), Gaps = 1/133 (0%)
Frame = +3
Query: 63 KEGLVPSNYVSQQTESIEN-PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAF 239
K + P S+ T ++ P+H AA G + + L N +V D+ G PLH A
Sbjct: 41 KRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACS 100
Query: 240 GGHYDCAKLLIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETP 419
GH + LL+ + ++ TPLH A++KG + +LL+ GA N D T
Sbjct: 101 FGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTA 160
Query: 420 YKLARNPECAALL 458
LA +P A+L
Sbjct: 161 LDLA-DPSAKAVL 172
Score = 58.2 bits (139), Expect = 2e-08
Identities = 37/111 (33%), Positives = 54/111 (48%), Gaps = 1/111 (0%)
Frame = +3
Query: 90 VSQQTESIENPMHEAAKRGNLEFLLE-CLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKL 266
+S + + EAAK G++E + + C V+ ++ TPLH+AA +
Sbjct: 485 ISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEY 544
Query: 267 LIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETP 419
L+ V K+K G PLHNA GH + ELL+K GA N + K TP
Sbjct: 545 LLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTP 595
Score = 54.3 bits (129), Expect = 2e-07
Identities = 36/98 (36%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Frame = +3
Query: 129 EAAKRGNLEFLLECLSN-KVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIKNK 305
E+A+ GN E ++ L+ V+ + D TPLH AA +LL+ V K+K
Sbjct: 183 ESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDK 242
Query: 306 LGETPLHNASLKGHAVLVELLLKSGANANALNNDKETP 419
PLHNA GH + ELL+K GA NA++ + TP
Sbjct: 243 GDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTP 280
Score = 54.3 bits (129), Expect = 2e-07
Identities = 33/108 (30%), Positives = 50/108 (46%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H AA ++ + L + V+ D PLH A GHY+ +LL+ V+
Sbjct: 214 PLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAM 273
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLARNPE 443
+ TPLH A+ K + LLL GA+ LN ++ LA P+
Sbjct: 274 DLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQ 321
Score = 50.1 bits (118), Expect = 4e-06
Identities = 29/108 (26%), Positives = 55/108 (50%)
Frame = +3
Query: 90 VSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLL 269
++++T+ P+H A+++ + + + + ++ VN LDN G T LH AA+ GH +LL
Sbjct: 393 INEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLL 452
Query: 270 IDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKE 413
+ C +I + G T L + V+ LL+ G + D++
Sbjct: 453 LSYGCDPNIISLQGFTALQMGNEN-----VQQLLQEGISLGNSEADRQ 495
Score = 45.1 bits (105), Expect = 1e-04
Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
Frame = +3
Query: 84 NYVSQQTESIENPMHEAA-----KRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGH 248
N+ QT E +H AA KR + LL L ++N TPLH A+ H
Sbjct: 357 NFKHPQTH--ETALHCAAASPYPKRKQICELL--LRKGANINEKTKEFLTPLHVASEKAH 412
Query: 249 YDCAKLLIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALN 401
D ++++ + +V+ + LG+T LH A+ GH LLL G + N ++
Sbjct: 413 NDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIIS 463
Score = 43.1 bits (100), Expect = 5e-04
Identities = 36/125 (28%), Positives = 47/125 (37%), Gaps = 21/125 (16%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H A G+ E + L + N DN TPLH AA G D +L+ + I+
Sbjct: 94 PLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIR 153
Query: 300 NKLGETPLHNASLKGHAVL---------------------VELLLKSGANANALNNDKET 416
N G T L A AVL + LL N +A + K T
Sbjct: 154 NTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKST 213
Query: 417 PYKLA 431
P LA
Sbjct: 214 PLHLA 218
Score = 38.1 bits (87), Expect = 0.016
Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Frame = +3
Query: 216 TPLHWAA---FGGHYDCAKLLIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGAN 386
T LH AA + +LL+ ++ K K TPLH AS K H +VE+++K A
Sbjct: 366 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 425
Query: 387 ANALNNDKET 416
NAL+N +T
Sbjct: 426 VNALDNLGQT 435
>sp|O95271|TNKS1_HUMAN Tankyrase 1 (TANK1) (Tankyrase I) (TNKS-1) (TRF1-interacting
ankyrin-related ADP-ribose polymerase)
Length = 1327
Score = 76.3 bits (186), Expect = 5e-14
Identities = 51/131 (38%), Positives = 63/131 (48%), Gaps = 1/131 (0%)
Frame = +3
Query: 78 PSNYVSQQTESIEN-PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYD 254
P N + T+ + P+H AA NLE L + VN D G PLH AA GH D
Sbjct: 825 PENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVD 884
Query: 255 CAKLLIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLAR 434
A LLI V+ +K TPLH A+ KG L LLL GA+ N + +TP LA
Sbjct: 885 IAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT 944
Query: 435 NPECAALLRSA 467
+ ALL A
Sbjct: 945 ADDIRALLIDA 955
Score = 65.9 bits (159), Expect = 7e-11
Identities = 37/105 (35%), Positives = 53/105 (50%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H AA + + L + V+ D G PLH A GHY+ A+LL+ V++
Sbjct: 687 PLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVA 746
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLAR 434
+ TPLH A+ KG + +LLLK GA+ N D TP L +
Sbjct: 747 DLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVK 791
Score = 63.5 bits (153), Expect = 4e-10
Identities = 48/151 (31%), Positives = 72/151 (47%), Gaps = 10/151 (6%)
Frame = +3
Query: 99 QTESIENPMHEAAKRGNLEFLLE-CLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLID 275
+T ++ + EA+K G+LE + + C S V+ L+ TPLH+AA + L+
Sbjct: 646 RTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLH 705
Query: 276 TKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA----RNPE 443
V K+K G PLHNA GH + ELL++ GA+ N + K TP A +
Sbjct: 706 HGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEI 765
Query: 444 CAALLRSADSNFKPNFE-----NYVDEEDSD 521
C LL+ K N + + V E D+D
Sbjct: 766 CKLLLKHGADPTKKNRDGNTPLDLVKEGDTD 796
Score = 59.7 bits (143), Expect = 5e-09
Identities = 40/98 (40%), Positives = 52/98 (53%), Gaps = 1/98 (1%)
Frame = +3
Query: 129 EAAKRGNLEFLLECLSN-KVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIKNK 305
EAA+ GN E L+ L+ V+ + D TPLH AA +LL+ V K+K
Sbjct: 341 EAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDK 400
Query: 306 LGETPLHNASLKGHAVLVELLLKSGANANALNNDKETP 419
G PLHNA GH + ELLLK GA NA++ + TP
Sbjct: 401 GGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTP 438
Score = 58.5 bits (140), Expect = 1e-08
Identities = 36/114 (31%), Positives = 58/114 (50%)
Frame = +3
Query: 117 NPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDI 296
+P+H AA G + + L +V+ D+ G PLH A GH + LL+ +
Sbjct: 218 SPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNA 277
Query: 297 KNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLARNPECAALL 458
++ TPLH A++KG + +LL+ GA+ N N D ++ LA +P A+L
Sbjct: 278 RDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA-DPSAKAVL 330
Score = 55.1 bits (131), Expect = 1e-07
Identities = 33/108 (30%), Positives = 50/108 (46%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H AA + + L + V+ D G PLH A GHY+ +LL+ V+
Sbjct: 372 PLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAM 431
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLARNPE 443
+ TPLH A+ K + LLL GA+ +N ++ +A PE
Sbjct: 432 DLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPE 479
Score = 53.5 bits (127), Expect = 4e-07
Identities = 44/152 (28%), Positives = 69/152 (45%), Gaps = 12/152 (7%)
Frame = +3
Query: 63 KEGLVPSNYVSQQTESIENPMH------EAAKRGNLEFLLE-CLSNKVSVNGLDNAGCTP 221
++G P + V + I++ + +AAK+G L + + C ++ TP
Sbjct: 781 RDGNTPLDLVKEGDTDIQDLLKGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTP 840
Query: 222 LHWAAFGGHYDCAKLLIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALN 401
LH AA + + A+ L++ V+ ++K G PLHNA+ GH + LL+K NA +
Sbjct: 841 LHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATD 900
Query: 402 NDKETPYKLA----RNPECAALL-RSADSNFK 482
TP A R CA LL AD K
Sbjct: 901 KWAFTPLHEAAQKGRTQLCALLLAHGADPTMK 932
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 5/107 (4%)
Frame = +3
Query: 96 QQTESIENPMHEAA-----KRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCA 260
+Q +S E +H A KR + LL L +VN + TPLH AA H D
Sbjct: 517 KQPQSHETALHCAVASLHPKRKQVTELL--LRKGANVNEKNKDFMTPLHVAAERAHNDVM 574
Query: 261 KLLIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALN 401
++L +++ + LG+T LH A+L GH LLL G++ + ++
Sbjct: 575 EVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIIS 621
Score = 37.0 bits (84), Expect = 0.036
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Frame = +3
Query: 216 TPLHWAAFGGH---YDCAKLLIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGAN 386
T LH A H +LL+ V+ KNK TPLH A+ + H ++E+L K GA
Sbjct: 524 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK 583
Query: 387 ANALNNDKET 416
NAL+ +T
Sbjct: 584 MNALDTLGQT 593
Score = 33.1 bits (74), Expect = 0.52
Identities = 37/161 (22%), Positives = 51/161 (31%), Gaps = 57/161 (35%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H A G+ E L + VN +D TPLH AA + LL+ +
Sbjct: 405 PLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLV 464
Query: 300 NKLGETPLHNA-----------SLKGHAVL------------------------------ 356
N G++ + A KGH++L
Sbjct: 465 NCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHET 524
Query: 357 ----------------VELLLKSGANANALNNDKETPYKLA 431
ELLL+ GAN N N D TP +A
Sbjct: 525 ALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVA 565
>sp|Q80YE7|DAPK1_MOUSE Death-associated protein kinase 1 (DAP kinase 1)
Length = 1442
Score = 76.3 bits (186), Expect = 5e-14
Identities = 42/121 (34%), Positives = 66/121 (54%)
Frame = +3
Query: 69 GLVPSNYVSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGH 248
G + S V+Q + P+ AA GN++ L + ++ D G ++WA+ GH
Sbjct: 365 GSLSSYDVNQPNKHGTPPLLIAAGCGNIQMLQLLIKRGSRIDVQDKGGSNAIYWASRHGH 424
Query: 249 YDCAKLLIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKL 428
D K L + KC +D+K+K GET LH A+ GHA +V+LL G+N + + ++ETP
Sbjct: 425 VDTLKFLNENKCPLDVKDKSGETALHVAARYGHADVVQLLCSFGSNPDFQDKEEETPLHC 484
Query: 429 A 431
A
Sbjct: 485 A 485
Score = 70.5 bits (171), Expect = 3e-12
Identities = 42/109 (38%), Positives = 61/109 (55%)
Frame = +3
Query: 105 ESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKC 284
+S E +H AA+ G+ + + S + + D TPLH AA+ G+Y AK L + C
Sbjct: 443 KSGETALHVAARYGHADVVQLLCSFGSNPDFQDKEEETPLHCAAWHGYYSVAKALCEVGC 502
Query: 285 QVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
V+IKN+ GETPL AS +G+ +VE L + GA+ NA + D LA
Sbjct: 503 NVNIKNREGETPLLTASARGYHDIVECLAEHGADLNASDKDGHIALHLA 551
Score = 63.2 bits (152), Expect = 5e-10
Identities = 38/104 (36%), Positives = 51/104 (49%)
Frame = +3
Query: 123 MHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIKN 302
+H A +R +E + L + V+ D G TPLH A G L + C +DI N
Sbjct: 548 LHLAVRRCQMEVIKTLLGHGSFVDFQDRHGNTPLHVACKDGSAPIVVALCEASCNLDISN 607
Query: 303 KLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLAR 434
K G TPLH A+ G +V L GAN AL +D +T LA+
Sbjct: 608 KYGRTPLHLAANNGILDVVRYLCLMGANVEALTSDGKTAEDLAK 651
Score = 60.8 bits (146), Expect = 2e-09
Identities = 36/110 (32%), Positives = 57/110 (51%)
Frame = +3
Query: 90 VSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLL 269
+ Q + N ++ A++ G+++ L NK ++ D +G T LH AA GH D +LL
Sbjct: 405 IDVQDKGGSNAIYWASRHGHVDTLKFLNENKCPLDVKDKSGETALHVAARYGHADVVQLL 464
Query: 270 IDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETP 419
D ++K ETPLH A+ G+ + + L + G N N N + ETP
Sbjct: 465 CSFGSNPDFQDKEEETPLHCAAWHGYYSVAKALCEVGCNVNIKNREGETP 514
Score = 48.9 bits (115), Expect = 9e-06
Identities = 35/109 (32%), Positives = 51/109 (46%), Gaps = 1/109 (0%)
Frame = +3
Query: 114 ENPMHEAAKRGNLEFLLECLSNK-VSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQV 290
E P+ A+ RG + ++ECL+ +N D G LH A + K L+ V
Sbjct: 512 ETPLLTASARGYHD-IVECLAEHGADLNASDKDGHIALHLAVRRCQMEVIKTLLGHGSFV 570
Query: 291 DIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLARN 437
D +++ G TPLH A G A +V L ++ N + N TP LA N
Sbjct: 571 DFQDRHGNTPLHVACKDGSAPIVVALCEASCNLDISNKYGRTPLHLAAN 619
Score = 33.1 bits (74), Expect = 0.52
Identities = 24/97 (24%), Positives = 40/97 (41%)
Frame = +3
Query: 84 NYVSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAK 263
++V Q P+H A K G+ ++ +++ + G TPLH AA G D +
Sbjct: 568 SFVDFQDRHGNTPLHVACKDGSAPIVVALCEASCNLDISNKYGRTPLHLAANNGILDVVR 627
Query: 264 LLIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLK 374
L V+ G+T A + H + LL +
Sbjct: 628 YLCLMGANVEALTSDGKTAEDLAKAEQHEHVAGLLAR 664
>sp|P16157|ANK1_HUMAN Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin R)
Length = 1881
Score = 74.7 bits (182), Expect = 2e-13
Identities = 38/105 (36%), Positives = 61/105 (58%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H A+ G++ + + V V+ G TPLH A+ G+ K L+ + V+ K
Sbjct: 671 PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAK 730
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLAR 434
KLG +PLH A+ +GH +V LLLK+GA+ N +++D TP +A+
Sbjct: 731 TKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAK 775
Score = 71.6 bits (174), Expect = 1e-12
Identities = 43/110 (39%), Positives = 59/110 (53%)
Frame = +3
Query: 102 TESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTK 281
TES P+H A+ G+L + L S N + TPLH AA GH + AK L+ K
Sbjct: 401 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 460
Query: 282 CQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
+V+ K K +TPLH A+ GH +V+LLL++ AN N TP +A
Sbjct: 461 AKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIA 510
Score = 67.4 bits (163), Expect = 2e-11
Identities = 35/104 (33%), Positives = 54/104 (51%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H A K+ ++ + L S++ + +G TPLH A+F GH K L+ ++
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 433
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
N ETPLH A+ GH + + LL++ A NA D +TP A
Sbjct: 434 NVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCA 477
Score = 67.4 bits (163), Expect = 2e-11
Identities = 38/107 (35%), Positives = 53/107 (49%)
Frame = +3
Query: 111 IENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQV 290
+E P+H AA+ G+ E L NK VN TPLH AA GH + KLL++
Sbjct: 437 VETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANP 496
Query: 291 DIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
++ G TPLH A+ +GH V LL+ A+ + TP +A
Sbjct: 497 NLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVA 543
Score = 65.5 bits (158), Expect = 9e-11
Identities = 40/103 (38%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Frame = +3
Query: 93 SQQTESIEN--PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKL 266
S ES++ P+H AA+ G+ E + LS + + N + +G TPLH A GH A +
Sbjct: 627 SANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADV 686
Query: 267 LIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANA 395
LI VD ++G TPLH AS G+ LV+ LL+ A+ NA
Sbjct: 687 LIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNA 729
Score = 65.1 bits (157), Expect = 1e-10
Identities = 38/114 (33%), Positives = 64/114 (56%)
Frame = +3
Query: 90 VSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLL 269
+ +T++ +P+H AA+ +L+ + L ++ + TPLH AA GH+ AK+L
Sbjct: 298 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVL 357
Query: 270 IDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
+D + + + G TPLH A K H ++ELLLK+GA+ +A+ TP +A
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVA 411
Score = 63.9 bits (154), Expect = 3e-10
Identities = 36/104 (34%), Positives = 52/104 (50%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H AAK+ +E L S N G TPLH AA GH + LL+ + ++
Sbjct: 605 PLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLG 664
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
NK G TPLH + +GH + ++L+K G +A TP +A
Sbjct: 665 NKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVA 708
Score = 63.5 bits (153), Expect = 4e-10
Identities = 33/105 (31%), Positives = 59/105 (56%)
Frame = +3
Query: 117 NPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDI 296
N +H A+K G+++ ++E L ++ + G T LH AA G + + L++ V+
Sbjct: 47 NGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNA 106
Query: 297 KNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
+++ G TPL+ A+ + H +V+ LL++GAN N D TP +A
Sbjct: 107 QSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 151
Score = 62.8 bits (151), Expect = 6e-10
Identities = 42/121 (34%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H AA NL L+ SVN G TPLH A+ G+ +LL+D Q++ K
Sbjct: 209 PLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 268
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLAR---NPECAALLRSAD 470
K TPLH A+ GH + E+LL GA A + +P +A + +C LL D
Sbjct: 269 TKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYD 328
Query: 471 S 473
+
Sbjct: 329 A 329
Score = 62.4 bits (150), Expect = 8e-10
Identities = 38/114 (33%), Positives = 57/114 (50%)
Frame = +3
Query: 90 VSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLL 269
V+ + + + P+H AA+ G+ + L N + N AG TPLH AA GH + L
Sbjct: 463 VNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLAL 522
Query: 270 IDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
++ + K G TPLH A+ G + ELLL+ A+ NA + TP +A
Sbjct: 523 LEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVA 576
Score = 61.2 bits (147), Expect = 2e-09
Identities = 38/104 (36%), Positives = 49/104 (47%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H AA G+ L N G TPLH A H +LL+ T +D
Sbjct: 341 PLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAV 400
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
+ G TPLH AS GH +V+ LL+ GA+ N N ETP +A
Sbjct: 401 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMA 444
Score = 59.3 bits (142), Expect = 7e-09
Identities = 34/114 (29%), Positives = 56/114 (49%)
Frame = +3
Query: 90 VSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLL 269
+ +T+ P+H AA+ G++ L + + G +P+H AA G H DC +LL
Sbjct: 265 IETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 324
Query: 270 IDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
+ ++D TPLH A+ GH + ++LL GA N+ + TP +A
Sbjct: 325 LQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIA 378
Score = 58.2 bits (139), Expect = 2e-08
Identities = 35/103 (33%), Positives = 52/103 (50%)
Frame = +3
Query: 123 MHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIKN 302
+H AA+ + L N + + L G TPLH AA + + A+LL++ V+
Sbjct: 177 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 236
Query: 303 KLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
+ G TPLH AS +G+ ++V LLL GA D+ TP A
Sbjct: 237 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCA 279
Score = 57.4 bits (137), Expect = 3e-08
Identities = 33/104 (31%), Positives = 51/104 (49%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H A++RGN+ + L + TPLH AA GH +++L+D + K
Sbjct: 242 PLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 301
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
K G +P+H A+ H V LLL+ A + + D TP +A
Sbjct: 302 TKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVA 345
Score = 56.2 bits (134), Expect = 6e-08
Identities = 35/100 (35%), Positives = 50/100 (50%)
Frame = +3
Query: 132 AAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIKNKLG 311
AA+ GNL+ L+ L N V +N + G LH A+ GH L+ + ++ K G
Sbjct: 19 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG 78
Query: 312 ETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
T LH A+L G +V L+ GAN NA + TP +A
Sbjct: 79 NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMA 118
Score = 56.2 bits (134), Expect = 6e-08
Identities = 38/121 (31%), Positives = 59/121 (48%)
Frame = +3
Query: 102 TESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTK 281
T + P+H AA+ G++E +L L + S + G TPLH AA G A+LL++
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 559
Query: 282 CQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLARNPECAALLR 461
+ K G TPLH A + +V+LLL G + ++ + TP +A + R
Sbjct: 560 AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVAR 619
Query: 462 S 464
S
Sbjct: 620 S 620
Score = 54.7 bits (130), Expect = 2e-07
Identities = 36/103 (34%), Positives = 49/103 (47%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H A NL+ + L S + G TPLH AA + A+ L+ + +
Sbjct: 572 PLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAE 631
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKL 428
+ G TPLH A+ +GHA +V LLL AN N N TP L
Sbjct: 632 SVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHL 674
Score = 52.4 bits (124), Expect = 8e-07
Identities = 40/122 (32%), Positives = 52/122 (42%), Gaps = 3/122 (2%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H AAK G + L N G TPLH A + D KLL+
Sbjct: 539 PLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 598
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLAR---NPECAALLRSAD 470
G TPLH A+ + + LL+ G +ANA + TP LA + E ALL S
Sbjct: 599 AWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQ 658
Query: 471 SN 476
+N
Sbjct: 659 AN 660
Score = 46.6 bits (109), Expect = 5e-05
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 9/121 (7%)
Frame = +3
Query: 102 TESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTK 281
T+ +H AA G E + E ++ +VN G TPL+ AA H + K L++
Sbjct: 75 TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG 134
Query: 282 CQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANAN---------ALNNDKETPYKLAR 434
++ + G TPL A +GH +V L+ G A N+D T L +
Sbjct: 135 ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQ 194
Query: 435 N 437
N
Sbjct: 195 N 195
Score = 46.6 bits (109), Expect = 5e-05
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 23/129 (17%)
Frame = +3
Query: 51 RANG----KEGLVPSNYVSQQ-------------------TESIENPMHEAAKRGNLEFL 161
+ANG K GL P + V+Q+ T P+H A+ GN++ +
Sbjct: 658 QANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLV 717
Query: 162 LECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIKNKLGETPLHNASLK 341
L ++ VN G +PLH AA GH D LL+ + + G TPL A
Sbjct: 718 KFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRL 777
Query: 342 GHAVLVELL 368
G+ + ++L
Sbjct: 778 GYISVTDVL 786
Score = 41.2 bits (95), Expect = 0.002
Identities = 40/137 (29%), Positives = 59/137 (43%), Gaps = 5/137 (3%)
Frame = +3
Query: 90 VSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLL 269
V+ Q++ P++ AA+ +LE + L N + N G TPL A GH + L
Sbjct: 104 VNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHL 163
Query: 270 IDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA---RNP 440
I+ K K+ LH A+ +LL++ N + L+ TP +A N
Sbjct: 164 IN----YGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENL 219
Query: 441 ECAALL--RSADSNFKP 485
A LL R A NF P
Sbjct: 220 NVAQLLLNRGASVNFTP 236
>sp|P53355|DAPK1_HUMAN Death-associated protein kinase 1 (DAP kinase 1)
Length = 1432
Score = 72.0 bits (175), Expect = 1e-12
Identities = 43/120 (35%), Positives = 64/120 (53%), Gaps = 3/120 (2%)
Frame = +3
Query: 81 SNY-VSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDC 257
SNY V+Q + P+ AA GN++ L + ++ D G ++WAA GH D
Sbjct: 368 SNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDT 427
Query: 258 AKLLIDTKCQVDIKNKLGETPLHNASLKGHA--VLVELLLKSGANANALNNDKETPYKLA 431
K L + KC +D+K+K GE LH A+ GHA V++L G+N N + ++ETP A
Sbjct: 428 LKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQVQVLCSFGSNPNIQDKEEETPLHCA 487
Score = 67.0 bits (162), Expect = 3e-11
Identities = 43/111 (38%), Positives = 61/111 (54%), Gaps = 2/111 (1%)
Frame = +3
Query: 105 ESIENPMHEAAKRGNLEF--LLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDT 278
+S E +H AA+ G+ + + S + N D TPLH AA+ G+Y AK L +
Sbjct: 443 KSGEMALHVAARYGHADVAQVQVLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEA 502
Query: 279 KCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
C V+IKN+ GETPL AS +G+ +VE L + GA+ NA + D LA
Sbjct: 503 GCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLA 553
Score = 65.5 bits (158), Expect = 9e-11
Identities = 39/107 (36%), Positives = 53/107 (49%)
Frame = +3
Query: 123 MHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIKN 302
+H A +R +E + LS V+ D G TPLH A G+ L + C +DI N
Sbjct: 550 LHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISN 609
Query: 303 KLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLARNPE 443
K G TPLH A+ G +V L GA+ AL D +T LAR+ +
Sbjct: 610 KYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQ 656
Score = 52.4 bits (124), Expect = 8e-07
Identities = 35/109 (32%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Frame = +3
Query: 114 ENPMHEAAKRGNLEFLLECLSNK-VSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQV 290
E P+ A+ RG + ++ECL+ +N D G LH A + K L+ C V
Sbjct: 514 ETPLLTASARGYHD-IVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFV 572
Query: 291 DIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLARN 437
D +++ G TPLH A G+ +V L ++ N + N TP LA N
Sbjct: 573 DYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAAN 621
Score = 35.4 bits (80), Expect = 0.11
Identities = 25/96 (26%), Positives = 40/96 (41%)
Frame = +3
Query: 87 YVSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKL 266
+V Q P+H A K GN+ ++ +++ + G TPLH AA G D +
Sbjct: 571 FVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRY 630
Query: 267 LIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLK 374
L V+ G+T A + H + LL +
Sbjct: 631 LCLMGASVEALTTDGKTAEDLARSEQHEHVAGLLAR 666
>sp|Q02357|ANK1_MOUSE Ankyrin-1 (Erythrocyte ankyrin)
Length = 1862
Score = 71.6 bits (174), Expect = 1e-12
Identities = 36/105 (34%), Positives = 62/105 (59%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H ++ G++ + + V+V+ G TPLH A+ G+ K L+ + V+ K
Sbjct: 667 PLHLVSQEGHVLVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAK 726
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLAR 434
KLG +PLH A+ +GH +V LLLK+GA+ N ++++ TP +A+
Sbjct: 727 TKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAK 771
Score = 69.3 bits (168), Expect = 7e-12
Identities = 36/104 (34%), Positives = 55/104 (52%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H A K+ ++ + L S++ + +G TPLH A+F GH K L+ ++
Sbjct: 370 PLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVS 429
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
N ETPLH A+ GH + + LL++ A ANA D +TP A
Sbjct: 430 NVKVETPLHMAARAGHTEVAKYLLQNKAKANAKAKDDQTPLHCA 473
Score = 69.3 bits (168), Expect = 7e-12
Identities = 42/110 (38%), Positives = 58/110 (52%)
Frame = +3
Query: 102 TESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTK 281
TES P+H A+ G+L + L S N + TPLH AA GH + AK L+ K
Sbjct: 397 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 456
Query: 282 CQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
+ + K K +TPLH A+ GH +V+LLL++GA+ N TP A
Sbjct: 457 AKANAKAKDDQTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTA 506
Score = 67.4 bits (163), Expect = 2e-11
Identities = 37/104 (35%), Positives = 53/104 (50%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H AAK+ +E L S N G TPLH AA GH + LL+ + ++
Sbjct: 601 PLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLG 660
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
NK G TPLH S +GH ++ ++L+K G +A TP +A
Sbjct: 661 NKSGLTPLHLVSQEGHVLVADVLIKHGVTVDATTRMGYTPLHVA 704
Score = 65.5 bits (158), Expect = 9e-11
Identities = 41/106 (38%), Positives = 54/106 (50%)
Frame = +3
Query: 114 ENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVD 293
+ P+H AA+ G+ + L N S N AG TPLH AA GH D A L++ +
Sbjct: 467 QTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQA 526
Query: 294 IKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
K G TPLH A+ G L ELLL+ A+ NA + TP +A
Sbjct: 527 CMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVA 572
Score = 65.1 bits (157), Expect = 1e-10
Identities = 38/114 (33%), Positives = 64/114 (56%)
Frame = +3
Query: 90 VSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLL 269
+ +T++ +P+H AA+ +L+ + L ++ + TPLH AA GH+ AK+L
Sbjct: 294 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVL 353
Query: 270 IDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
+D + + + G TPLH A K H ++ELLLK+GA+ +A+ TP +A
Sbjct: 354 LDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVA 407
Score = 63.5 bits (153), Expect = 4e-10
Identities = 33/105 (31%), Positives = 59/105 (56%)
Frame = +3
Query: 117 NPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDI 296
N +H A+K G+++ ++E L ++ + G T LH AA G + + L++ V+
Sbjct: 43 NGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNA 102
Query: 297 KNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
+++ G TPL+ A+ + H +V+ LL++GAN N D TP +A
Sbjct: 103 QSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 147
Score = 63.5 bits (153), Expect = 4e-10
Identities = 36/107 (33%), Positives = 50/107 (46%)
Frame = +3
Query: 111 IENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQV 290
+E P+H AA+ G+ E L NK N TPLH AA GH KLL++
Sbjct: 433 VETPLHMAARAGHTEVAKYLLQNKAKANAKAKDDQTPLHCAARIGHTGMVKLLLENGASP 492
Query: 291 DIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
++ G TPLH A+ +GH LL+ A+ + TP +A
Sbjct: 493 NLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVA 539
Score = 62.8 bits (151), Expect = 6e-10
Identities = 39/103 (37%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Frame = +3
Query: 93 SQQTESIEN--PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKL 266
S ES++ P+H AA+ G+ E + LS + + N + +G TPLH + GH A +
Sbjct: 623 SANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVLVADV 682
Query: 267 LIDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANA 395
LI VD ++G TPLH AS G+ LV+ LL+ A+ NA
Sbjct: 683 LIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNA 725
Score = 61.2 bits (147), Expect = 2e-09
Identities = 38/104 (36%), Positives = 49/104 (47%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H AA G+ L N G TPLH A H +LL+ T +D
Sbjct: 337 PLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAV 396
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
+ G TPLH AS GH +V+ LL+ GA+ N N ETP +A
Sbjct: 397 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMA 440
Score = 60.5 bits (145), Expect = 3e-09
Identities = 40/116 (34%), Positives = 57/116 (49%), Gaps = 3/116 (2%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H AA NL L+ SVN G TPLH A+ G+ +LL+D Q++ +
Sbjct: 205 PLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETR 264
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLAR---NPECAALL 458
K TPLH A+ GH + E+LL GA A + +P +A + +C LL
Sbjct: 265 TKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 320
Score = 59.7 bits (143), Expect = 5e-09
Identities = 34/114 (29%), Positives = 56/114 (49%)
Frame = +3
Query: 90 VSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLL 269
+ +T+ P+H AA+ G++ L + + G +P+H AA G H DC +LL
Sbjct: 261 IETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 320
Query: 270 IDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
+ ++D TPLH A+ GH + ++LL GA N+ + TP +A
Sbjct: 321 LQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIA 374
Score = 58.2 bits (139), Expect = 2e-08
Identities = 35/103 (33%), Positives = 52/103 (50%)
Frame = +3
Query: 123 MHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIKN 302
+H AA+ + L N + + L G TPLH AA + + A+LL++ V+
Sbjct: 173 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 232
Query: 303 KLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
+ G TPLH AS +G+ ++V LLL GA D+ TP A
Sbjct: 233 QNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCA 275
Score = 57.8 bits (138), Expect = 2e-08
Identities = 33/104 (31%), Positives = 51/104 (49%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H A++RGN+ + L + TPLH AA GH +++L+D + K
Sbjct: 238 PLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 297
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
K G +P+H A+ H V LLL+ A + + D TP +A
Sbjct: 298 TKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVA 341
Score = 56.2 bits (134), Expect = 6e-08
Identities = 35/100 (35%), Positives = 50/100 (50%)
Frame = +3
Query: 132 AAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIKNKLG 311
AA+ GNL+ L+ L N V +N + G LH A+ GH L+ + ++ K G
Sbjct: 15 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG 74
Query: 312 ETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA 431
T LH A+L G +V L+ GAN NA + TP +A
Sbjct: 75 NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMA 114
Score = 54.3 bits (129), Expect = 2e-07
Identities = 37/121 (30%), Positives = 58/121 (47%)
Frame = +3
Query: 102 TESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTK 281
T + P+H AA+ G+++ L L + S + G TPLH AA G A+LL++
Sbjct: 496 TTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHD 555
Query: 282 CQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLARNPECAALLR 461
+ K G TPLH A + +V+LLL G + ++ + TP +A + R
Sbjct: 556 AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVAR 615
Query: 462 S 464
S
Sbjct: 616 S 616
Score = 53.1 bits (126), Expect = 5e-07
Identities = 35/103 (33%), Positives = 48/103 (46%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H A NL+ + L S + G TPLH AA + A+ L+ + +
Sbjct: 568 PLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAE 627
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKL 428
+ G TPLH A+ +GH +V LLL AN N N TP L
Sbjct: 628 SVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHL 670
Score = 52.8 bits (125), Expect = 6e-07
Identities = 40/122 (32%), Positives = 53/122 (43%), Gaps = 3/122 (2%)
Frame = +3
Query: 120 PMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIK 299
P+H AAK G + L + N G TPLH A + D KLL+
Sbjct: 535 PLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 594
Query: 300 NKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLAR---NPECAALLRSAD 470
G TPLH A+ + + LL+ G +ANA + TP LA + E ALL S
Sbjct: 595 AWNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQ 654
Query: 471 SN 476
+N
Sbjct: 655 AN 656
Score = 48.1 bits (113), Expect = 2e-05
Identities = 37/129 (28%), Positives = 55/129 (42%), Gaps = 23/129 (17%)
Frame = +3
Query: 51 RANG----KEGLVPSNYVSQQ-------------------TESIENPMHEAAKRGNLEFL 161
+ANG K GL P + VSQ+ T P+H A+ GN++ +
Sbjct: 654 QANGNLGNKSGLTPLHLVSQEGHVLVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLV 713
Query: 162 LECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTKCQVDIKNKLGETPLHNASLK 341
L ++ VN G +PLH AA GH D LL+ + + G TPL A
Sbjct: 714 KFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRL 773
Query: 342 GHAVLVELL 368
G+ + ++L
Sbjct: 774 GYISVTDVL 782
Score = 46.6 bits (109), Expect = 5e-05
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 9/121 (7%)
Frame = +3
Query: 102 TESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLLIDTK 281
T+ +H AA G E + E ++ +VN G TPL+ AA H + K L++
Sbjct: 71 TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG 130
Query: 282 CQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANAN---------ALNNDKETPYKLAR 434
++ + G TPL A +GH +V L+ G A N+D T L +
Sbjct: 131 ANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQ 190
Query: 435 N 437
N
Sbjct: 191 N 191
Score = 41.2 bits (95), Expect = 0.002
Identities = 40/137 (29%), Positives = 59/137 (43%), Gaps = 5/137 (3%)
Frame = +3
Query: 90 VSQQTESIENPMHEAAKRGNLEFLLECLSNKVSVNGLDNAGCTPLHWAAFGGHYDCAKLL 269
V+ Q++ P++ AA+ +LE + L N + N G TPL A GH + L
Sbjct: 100 VNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHL 159
Query: 270 IDTKCQVDIKNKLGETPLHNASLKGHAVLVELLLKSGANANALNNDKETPYKLA---RNP 440
I+ K K+ LH A+ +LL++ N + L+ TP +A N
Sbjct: 160 IN----YGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENL 215
Query: 441 ECAALL--RSADSNFKP 485
A LL R A NF P
Sbjct: 216 NVAQLLLNRGASVNFTP 232
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,077,884
Number of Sequences: 369166
Number of extensions: 1307759
Number of successful extensions: 5633
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3886
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5086
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4357244645
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)