Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_004_I08 (885 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P07688|CATB_BOVIN Cathepsin B precursor [Contains: Cathe... 329 7e-90 sp|P00787|CATB_RAT Cathepsin B precursor (Cathepsin B1) (RS... 321 1e-87 sp|P10605|CATB_MOUSE Cathepsin B precursor (Cathepsin B1) [... 321 1e-87 sp|P07858|CATB_HUMAN Cathepsin B precursor (Cathepsin B1) (... 317 4e-86 sp|P43233|CATB_CHICK Cathepsin B precursor (Cathepsin B1) [... 307 2e-83 sp|P43157|CYSP_SCHJA Cathepsin B-like cysteine proteinase p... 296 4e-80 sp|P25792|CYSP_SCHMA Cathepsin B-like cysteine proteinase p... 278 1e-74 sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6... 242 1e-63 sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precu... 229 8e-60 sp|P43509|CPR5_CAEEL Cathepsin B-like cysteine proteinase 5... 227 3e-59
>sp|P07688|CATB_BOVIN Cathepsin B precursor [Contains: Cathepsin B light chain; Cathepsin B heavy chain] Length = 335 Score = 329 bits (843), Expect = 7e-90 Identities = 157/263 (59%), Positives = 189/263 (71%), Gaps = 1/263 (0%) Frame = +2 Query: 77 PLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLG-VMKDPNNFKLPKRKPLLNRVRL 253 PLS +L+N+VN TTWKAG +S ++K+ G ++ P KLP+R V L Sbjct: 25 PLSDELVNFVNK-QNTTWKAGHNFYNVDLSYVKKLCGAILGGP---KLPQRDAFAADVVL 80 Query: 254 PTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAEDLLT 433 P +FDAR QWP C +I EIRDQ +CGSCWAFGAVEAI+DR CIHSNG +SAED+LT Sbjct: 81 PESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDMLT 140 Query: 434 CCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTG 613 CCG CGDGCNGGFPSGAW++W GLV+GG Y +H+GC+ Y+ P C HHV G P CTG Sbjct: 141 CCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCTG 200 Query: 614 EFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYADFP 793 E TPKC K C+ GYS +Y EDK +G SSYSV +N++ IM EI NGPVE AFSVY+DF Sbjct: 201 EGDTPKCNKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDFL 260 Query: 794 SYKSGVYQHVSRGMLGGHAIRFL 862 YKSGVYQHVS ++GGHAIR L Sbjct: 261 LYKSGVYQHVSGEIMGGHAIRIL 283
>sp|P00787|CATB_RAT Cathepsin B precursor (Cathepsin B1) (RSG-2) [Contains: Cathepsin B light chain; Cathepsin B heavy chain] Length = 339 Score = 321 bits (823), Expect = 1e-87 Identities = 150/267 (56%), Positives = 188/267 (70%), Gaps = 1/267 (0%) Frame = +2 Query: 65 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLG-VMKDPNNFKLPKRKPLLN 241 P PLS D+INY+N TTW+AG IS ++K+ G V+ PN LP+R Sbjct: 21 PSSHPLSDDMINYINK-QNTTWQAGRNFYNVDISYLKKLCGTVLGGPN---LPERVGFSE 76 Query: 242 RVRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAE 421 + LP +FDAR QW C +I +IRDQ +CGSCWAFGAVEA++DR CIH+NG +SAE Sbjct: 77 DINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAE 136 Query: 422 DLLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYP 601 DLLTCCG +CGDGCNGG+PSGAW++W GLV+GG Y +H+GC Y P C HHV G P Sbjct: 137 DLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRP 196 Query: 602 NCTGEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVY 781 CTGE TPKC K C+AGYS +Y EDK YG +SYSV +++ IM EI NGPVE AF+V+ Sbjct: 197 PCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVF 256 Query: 782 ADFPSYKSGVYQHVSRGMLGGHAIRFL 862 +DF +YKSGVY+H + ++GGHAIR L Sbjct: 257 SDFLTYKSGVYKHEAGDVMGGHAIRIL 283
>sp|P10605|CATB_MOUSE Cathepsin B precursor (Cathepsin B1) [Contains: Cathepsin B light chain; Cathepsin B heavy chain] Length = 339 Score = 321 bits (823), Expect = 1e-87 Identities = 153/267 (57%), Positives = 188/267 (70%), Gaps = 1/267 (0%) Frame = +2 Query: 65 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLG-VMKDPNNFKLPKRKPLLN 241 P PLS DLINY+N TTW+AG IS ++K+ G V+ P KLP R Sbjct: 21 PSFHPLSDDLINYINK-QNTTWQAGRNFYNVDISYLKKLCGTVLGGP---KLPGRVAFGE 76 Query: 242 RVRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAE 421 + LP TFDAR QW C +IG+IRDQ +CGSCWAFGAVEAI+DR CIH+NG +SAE Sbjct: 77 DIDLPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAE 136 Query: 422 DLLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYP 601 DLLTCCG +CGDGCNGG+PSGAW +W GLV+GG Y +H+GC Y P C HHV G P Sbjct: 137 DLLTCCGIQCGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCLPYTIPPCEHHVNGSRP 196 Query: 602 NCTGEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVY 781 CTGE TP+C K+C+AGYS +Y EDK +G +SYSV ++ + IM EI NGPVE AF+V+ Sbjct: 197 PCTGEGDTPRCNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVEGAFTVF 256 Query: 782 ADFPSYKSGVYQHVSRGMLGGHAIRFL 862 +DF +YKSGVY+H + M+GGHAIR L Sbjct: 257 SDFLTYKSGVYKHEAGDMMGGHAIRIL 283
>sp|P07858|CATB_HUMAN Cathepsin B precursor (Cathepsin B1) (APP secretase) (APPS) [Contains: Cathepsin B light chain; Cathepsin B heavy chain] Length = 339 Score = 317 bits (811), Expect = 4e-86 Identities = 149/266 (56%), Positives = 187/266 (70%) Frame = +2 Query: 65 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLGVMKDPNNFKLPKRKPLLNR 244 P PLS +L+NYVN TTW+AG +S ++++ G K P+R Sbjct: 21 PSFHPLSDELVNYVNK-RNTTWQAGHNFYNVDMSYLKRLCGTFL--GGPKPPQRVMFTED 77 Query: 245 VRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAED 424 ++LP +FDAR QWP+C +I EIRDQ +CGSCWAFGAVEAI+DR CIH+N + +SAED Sbjct: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 Query: 425 LLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPN 604 LLTCCG CGDGCNGG+P+ AW++W GLV+GG Y +H+GC+ Y+ P C HHV G P Sbjct: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 Query: 605 CTGEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYA 784 CTGE TPKC K C+ GYS TY +DK YG +SYSV ++++ IM EI NGPVE AFSVY+ Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 257 Query: 785 DFPSYKSGVYQHVSRGMLGGHAIRFL 862 DF YKSGVYQHV+ M+GGHAIR L Sbjct: 258 DFLLYKSGVYQHVTGEMMGGHAIRIL 283
>sp|P43233|CATB_CHICK Cathepsin B precursor (Cathepsin B1) [Contains: Cathepsin B light chain; Cathepsin B heavy chain] Length = 340 Score = 307 bits (787), Expect = 2e-83 Identities = 146/268 (54%), Positives = 180/268 (67%), Gaps = 1/268 (0%) Frame = +2 Query: 62 IPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLGVMKDPNNFKLPKRKPLLN 241 IP + PLS DL+N++N + TT +AG +S ++K+ G K P+R Sbjct: 20 IPYYPPLSSDLVNHINKL-NTTGRAGHNFHNTDMSYVKKLCGTFL--GGPKAPERVDFAE 76 Query: 242 RVRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAE 421 + LP TFD R QWP C +I EIRDQ +CGSCWAFGAVEAI+DR C+H+N + +SAE Sbjct: 77 DMDLPDTFDTRKQWPNCPTISEIRDQGSCGSCWAFGAVEAISDRICVHTNAKVSVEVSAE 136 Query: 422 DLLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYP 601 DLL+CCGF CG GCNGG+PSGAW YW GLV+GG Y +H+GC+ Y P C HHV G P Sbjct: 137 DLLSCCGFECGMGCNGGYPSGAWRYWTERGLVSGGLYDSHVGCRAYTIPPCEHHVNGSRP 196 Query: 602 NCTGE-FPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSV 778 CTGE TP+C + C+ GYS +Y EDK YG +SY V +++ IM EI NGPVE AF V Sbjct: 197 PCTGEGGETPRCSRHCEPGYSPSYKEDKHYGITSYGVPRSEKEIMAEIYKNGPVEGAFIV 256 Query: 779 YADFPSYKSGVYQHVSRGMLGGHAIRFL 862 Y DF YKSGVYQHVS +GGHAIR L Sbjct: 257 YEDFLMYKSGVYQHVSGEQVGGHAIRIL 284
>sp|P43157|CYSP_SCHJA Cathepsin B-like cysteine proteinase precursor (Antigen Sj31) Length = 342 Score = 296 bits (759), Expect = 4e-80 Identities = 138/267 (51%), Positives = 180/267 (67%), Gaps = 5/267 (1%) Frame = +2 Query: 77 PLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLGVMKDPNNFKLPKRKPLLNR---- 244 PLS ++I+++N WKA + RF S+ D R ++G K+ K R+P ++ Sbjct: 29 PLSDEMISFINEHPDAGWKADKSDRFHSLDDARILMGARKEDAEMKR-NRRPTVDHHDLN 87 Query: 245 VRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAED 424 V +P+ FD+R +WP CKSI +IRDQS CGSCWAFGAVEA+TDR CI S G Q+ +SA D Sbjct: 88 VEIPSQFDSRKKWPHCKSISQIRDQSRCGSCWAFGAVEAMTDRICIQSGGGQSAELSALD 147 Query: 425 LLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPN 604 L++CC CGDGC GGFP AW YWV G+VTGG H GCQ Y FPKC HH G YP Sbjct: 148 LISCCK-DCGDGCQGGFPGVAWDYWVKRGIVTGGSKENHTGCQPYPFPKCEHHTKGKYPA 206 Query: 605 C-TGEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVY 781 C T + TP+CK+ CQ GY Y +DK YG SY+V +N++ I ++I+ GPVEAAF VY Sbjct: 207 CGTKIYKTPQCKQTCQKGYKTPYEQDKHYGDESYNVQNNEKVIQRDIMMYGPVEAAFDVY 266 Query: 782 ADFPSYKSGVYQHVSRGMLGGHAIRFL 862 DF +YKSG+Y+HV+ ++GGHAIR + Sbjct: 267 EDFLNYKSGIYRHVTGSIVGGHAIRII 293
>sp|P25792|CYSP_SCHMA Cathepsin B-like cysteine proteinase precursor (Antigen Sm31) Length = 340 Score = 278 bits (711), Expect = 1e-74 Identities = 131/267 (49%), Positives = 176/267 (65%), Gaps = 5/267 (1%) Frame = +2 Query: 77 PLSFDLINYVNYIAQTTWKAGPTTRFQSISDIRKVLGVMKDPNNFKLPKRKPLLNR---- 244 PLS D+I+Y+N W+A + RF S+ D R +G ++ + + KR+P ++ Sbjct: 28 PLSDDIISYINEHPNAGWRAEKSNRFHSLDDARIQMGARREEPDLRR-KRRPTVDHNDWN 86 Query: 245 VRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAED 424 V +P+ FD+R +WP CKSI IRDQS CGSCW+FGAVEA++DR CI S G Q +SA D Sbjct: 87 VEIPSNFDSRKKWPGCKSIATIRDQSRCGSCWSFGAVEAMSDRSCIQSGGKQNVELSAVD 146 Query: 425 LLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPN 604 LLTCC CG GC GG AW YWV +G+VT H GC+ Y FPKC HH G YP Sbjct: 147 LLTCCE-SCGLGCEGGILGPAWDYWVKEGIVTASSKENHTGCEPYPFPKCEHHTKGKYPP 205 Query: 605 CTGE-FPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVY 781 C + + TP+CK+ CQ Y Y +DK GKSSY+V ++++AI +EI+ GPVEA+F+VY Sbjct: 206 CGSKIYNTPRCKQTCQRKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEASFTVY 265 Query: 782 ADFPSYKSGVYQHVSRGMLGGHAIRFL 862 DF +YKSG+Y+H++ LGGHAIR + Sbjct: 266 EDFLNYKSGIYKHITGEALGGHAIRII 292
>sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6 precursor (Cysteine protease-related 6) Length = 379 Score = 242 bits (617), Expect = 1e-63 Identities = 128/270 (47%), Positives = 170/270 (62%), Gaps = 12/270 (4%) Frame = +2 Query: 89 DLINYVNYIAQTTWKAGPTTRFQSI-SDIRKVLGVMKDPNNFKLP-KRKPLLNRVR---- 250 DLI+YVN Q W A RF S+ + K + N+ +L K K L++ + Sbjct: 45 DLIDYVNE-NQNLWTAKKQRRFSSVYGENDKAKWGLMGVNHVRLSVKGKQHLSKTKDLDL 103 Query: 251 -LPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAEDL 427 +P +FD+R WPKC SI IRDQS+CGSCWAFGAVEA++DR CI S+G +SA+DL Sbjct: 104 DIPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDL 163 Query: 428 LTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHV----IGP 595 L+CC CG GCNGG P AW YWV DG+VTG Y A+ GC+ Y FP C HH P Sbjct: 164 LSCCK-SCGFGCNGGDPLAAWRYWVKDGIVTGSNYTANNGCKPYPFPPCEHHSKKTHFDP 222 Query: 596 YPNCTGEFPTPKCKKACQAGYS-KTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAF 772 P+ +PTPKC+K C + Y+ KTY+EDK +G S+Y V + +AI +E++T+GP+E AF Sbjct: 223 CPH--DLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAF 280 Query: 773 SVYADFPSYKSGVYQHVSRGMLGGHAIRFL 862 VY DF +Y GVY H + GGHA++ + Sbjct: 281 EVYEDFLNYDGGVYVHTGGKLGGGHAVKLI 310
>sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precursor Length = 329 Score = 229 bits (584), Expect = 8e-60 Identities = 109/204 (53%), Positives = 136/204 (66%) Frame = +2 Query: 251 LPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAEDLL 430 +P TFD+R QW +CKSI IRDQ+ CGSCWAFGA E I+DR CI + G Q P IS +DLL Sbjct: 85 VPATFDSRTQWSECKSIKLIRDQATCGSCWAFGAAEMISDRTCIETKGAQQPIISPDDLL 144 Query: 431 TCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCT 610 +CCG CG+GC GG+P A +W + G+VTGG+Y GC+ Y C+ NC Sbjct: 145 SCCGSSCGNGCEGGYPIQALRWWDSKGVVTGGDYHG-AGCKPYPIAPCTS------GNCP 197 Query: 611 GEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYADF 790 E TP C +CQ+GYS YA+DK +G S+Y+V N +I EI NGPVEAAFSVY DF Sbjct: 198 -ESKTPSCSMSCQSGYSTAYAKDKHFGVSAYAVPKNAASIQAEIYANGPVEAAFSVYEDF 256 Query: 791 PSYKSGVYQHVSRGMLGGHAIRFL 862 YKSGVY+H + LGGHAI+ + Sbjct: 257 YKYKSGVYKHTAGKYLGGHAIKII 280
>sp|P43509|CPR5_CAEEL Cathepsin B-like cysteine proteinase 5 precursor (Cysteine protease-related 5) Length = 344 Score = 227 bits (579), Expect = 3e-59 Identities = 120/266 (45%), Positives = 155/266 (58%), Gaps = 9/266 (3%) Frame = +2 Query: 92 LINYVNYIAQTTWKAGPTTRFQSISDIRKVLGVMKDPNNFKLPKRKPLLNRV---RLPTT 262 LI+YVN AQ W AG + K+ + D K + ++ +P Sbjct: 32 LIDYVNS-AQKLWTAG-----HQVIPKEKITKKLMDVKYLVPHKDEDIVATEVSDAIPDH 85 Query: 263 FDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAEDLLTCCG 442 FDAR QWP C SI IRDQS+CGSCWAF A EAI+DR CI SNG +S+EDLL+CC Sbjct: 86 FDARDQWPNCMSINNIRDQSDCGSCWAFAAAEAISDRTCIASNGAVNTLLSSEDLLSCCT 145 Query: 443 --FRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIG-PYPNCTG 613 F CG+GC GG+P AW +WV GLVTGG Y GC+ Y+ C V G +P C Sbjct: 146 GMFSCGNGCEGGYPIQAWKWWVKHGLVTGGSYETQFGCKPYSIAPCGETVNGVKWPACPE 205 Query: 614 EF-PTPKCKKACQA--GYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYA 784 + PTPKC +C + Y+ Y +DK +G ++Y+V + I EILTNGP+E AF+VY Sbjct: 206 DTEPTPKCVDSCTSKNNYATPYLQDKHFGSTAYAVGKKVEQIQTEILTNGPIEVAFTVYE 265 Query: 785 DFPSYKSGVYQHVSRGMLGGHAIRFL 862 DF Y +GVY H + LGGHA++ L Sbjct: 266 DFYQYTTGVYVHTAGASLGGHAVKIL 291
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 110,447,287 Number of Sequences: 369166 Number of extensions: 2459432 Number of successful extensions: 7436 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 6838 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7260 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 8838279920 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)