Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_I03
(677 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8TBG9|SYNPR_HUMAN Synaptoporin 101 2e-21
sp|Q8BGN8|SYNPR_MOUSE Synaptoporin 101 2e-21
sp|P22831|SYNPR_RAT Synaptoporin 101 2e-21
sp|P08247|SYPH_HUMAN Synaptophysin (Major synaptic vesicle ... 99 1e-20
sp|P07825|SYPH_RAT Synaptophysin (Major synaptic vesicle pr... 99 1e-20
sp|Q62277|SYPH_MOUSE Synaptophysin (Major synaptic vesicle ... 99 1e-20
sp|P20488|SYPH_BOVIN Synaptophysin (Major synaptic vesicle ... 97 5e-20
sp|Q5VXT5|SYPL2_HUMAN Synaptophysin-like protein 2 89 1e-17
sp|O89104|SYPL2_MOUSE Synaptophysin-like protein 2 (Mitsugu... 88 2e-17
sp|O62646|SYPL2_RABIT Synaptophysin-like protein 2 (Mitsugu... 87 3e-17
>sp|Q8TBG9|SYNPR_HUMAN Synaptoporin
Length = 265
Score = 101 bits (252), Expect = 2e-21
Identities = 47/107 (43%), Positives = 68/107 (63%), Gaps = 2/107 (1%)
Frame = +2
Query: 5 ILYVFFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILDIEY 184
++Y+FF +N+R P IDFI+T V + LW + S AWA G+S +K+ TDP +++L +
Sbjct: 98 VVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSA 157
Query: 185 CK--SATCTASVNGSYGGLNASLIAGFANIALWAANLWFLFKETLWY 319
CK S C A + LN S++ GF N LWA N+WF+FKET W+
Sbjct: 158 CKQPSNKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWH 204
>sp|Q8BGN8|SYNPR_MOUSE Synaptoporin
Length = 265
Score = 101 bits (252), Expect = 2e-21
Identities = 47/107 (43%), Positives = 68/107 (63%), Gaps = 2/107 (1%)
Frame = +2
Query: 5 ILYVFFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILDIEY 184
++Y+FF +N+R P IDFI+T V + LW + S AWA G+S +K+ TDP +++L +
Sbjct: 98 VVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSA 157
Query: 185 CK--SATCTASVNGSYGGLNASLIAGFANIALWAANLWFLFKETLWY 319
CK S C A + LN S++ GF N LWA N+WF+FKET W+
Sbjct: 158 CKQPSNKCMAVHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWH 204
>sp|P22831|SYNPR_RAT Synaptoporin
Length = 265
Score = 101 bits (252), Expect = 2e-21
Identities = 47/107 (43%), Positives = 68/107 (63%), Gaps = 2/107 (1%)
Frame = +2
Query: 5 ILYVFFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILDIEY 184
++Y+FF +N+R P IDFI+T V + LW + S AWA G+S +K+ TDP +++L +
Sbjct: 98 VVYIFFQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSA 157
Query: 185 CK--SATCTASVNGSYGGLNASLIAGFANIALWAANLWFLFKETLWY 319
CK S C A + LN S++ GF N LWA N+WF+FKET W+
Sbjct: 158 CKQPSNKCMAVHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWH 204
>sp|P08247|SYPH_HUMAN Synaptophysin (Major synaptic vesicle protein p38)
Length = 313
Score = 99.0 bits (245), Expect = 1e-20
Identities = 45/104 (43%), Positives = 63/104 (60%), Gaps = 2/104 (1%)
Frame = +2
Query: 11 YVFFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILDIEYCK 190
Y+F +N++ P +DF+ TAV A +W + S AWA G+S +KM TDP II ++ C+
Sbjct: 125 YIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPVCR 184
Query: 191 SA--TCTASVNGSYGGLNASLIAGFANIALWAANLWFLFKETLW 316
TC + GLN S++ GF N+ LW NLWF+FKET W
Sbjct: 185 QTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGW 228
>sp|P07825|SYPH_RAT Synaptophysin (Major synaptic vesicle protein p38)
Length = 307
Score = 98.6 bits (244), Expect = 1e-20
Identities = 45/104 (43%), Positives = 63/104 (60%), Gaps = 2/104 (1%)
Frame = +2
Query: 11 YVFFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILDIEYCK 190
Y+F +N++ P +DF+ TAV A +W + S AWA G+S +KM TDP II ++ C+
Sbjct: 120 YIFLQNKYRENNKGPMMDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPMCR 179
Query: 191 SA--TCTASVNGSYGGLNASLIAGFANIALWAANLWFLFKETLW 316
TC + GLN S++ GF N+ LW NLWF+FKET W
Sbjct: 180 QTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGW 223
>sp|Q62277|SYPH_MOUSE Synaptophysin (Major synaptic vesicle protein p38) (BM89 antigen)
Length = 314
Score = 98.6 bits (244), Expect = 1e-20
Identities = 45/104 (43%), Positives = 63/104 (60%), Gaps = 2/104 (1%)
Frame = +2
Query: 11 YVFFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILDIEYCK 190
Y+F +N++ P +DF+ TAV A +W + S AWA G+S +KM TDP II ++ C+
Sbjct: 126 YIFLQNKYRENNKGPMMDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPMCR 185
Query: 191 SA--TCTASVNGSYGGLNASLIAGFANIALWAANLWFLFKETLW 316
TC + GLN S++ GF N+ LW NLWF+FKET W
Sbjct: 186 QTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGW 229
>sp|P20488|SYPH_BOVIN Synaptophysin (Major synaptic vesicle protein p38)
Length = 313
Score = 96.7 bits (239), Expect = 5e-20
Identities = 45/104 (43%), Positives = 61/104 (58%), Gaps = 2/104 (1%)
Frame = +2
Query: 11 YVFFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILDIEYCK 190
Y+F +N++ P +DF+ TAV A +W + S AWA G+S +KM TDP II + C
Sbjct: 125 YIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKGMHVCH 184
Query: 191 SA--TCTASVNGSYGGLNASLIAGFANIALWAANLWFLFKETLW 316
TC + GLN S++ GF N+ LW NLWF+FKET W
Sbjct: 185 QPGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGW 228
>sp|Q5VXT5|SYPL2_HUMAN Synaptophysin-like protein 2
Length = 272
Score = 89.0 bits (219), Expect = 1e-17
Identities = 39/116 (33%), Positives = 62/116 (53%), Gaps = 2/116 (1%)
Frame = +2
Query: 2 IILYVFFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILDIE 181
+++Y+ F + +N R P +DF +T W + + AW G++ +K T P+ + +
Sbjct: 133 LVIYLRFHNLYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMS 192
Query: 182 YC--KSATCTASVNGSYGGLNASLIAGFANIALWAANLWFLFKETLWYERRNPSDQ 343
C + A C+A S G N S++ GF N LWA N WF+FKET W+ + DQ
Sbjct: 193 VCHGEEAVCSAGATPSMGLANISVLFGFINFFLWAGNCWFVFKETPWHGQGQGQDQ 248
>sp|O89104|SYPL2_MOUSE Synaptophysin-like protein 2 (Mitsugumin-29) (Mg29)
Length = 264
Score = 87.8 bits (216), Expect = 2e-17
Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 2/122 (1%)
Frame = +2
Query: 2 IILYVFFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILDIE 181
+++Y+ F ++ +N R P +DF +T W + + AW G++ +K T P+ + +
Sbjct: 133 LVIYLRFHKLYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMS 192
Query: 182 YC--KSATCTASVNGSYGGLNASLIAGFANIALWAANLWFLFKETLWYERRNPSDQIIGN 355
C + A C+A S G N S++ GF N LWA N WF+FKET W+ + Q
Sbjct: 193 VCHGEEAVCSAGATPSMGLANLSVLFGFINFFLWAGNCWFVFKETPWHGQGQDQGQGPSQ 252
Query: 356 ES 361
ES
Sbjct: 253 ES 254
>sp|O62646|SYPL2_RABIT Synaptophysin-like protein 2 (Mitsugumin-29)
Length = 264
Score = 87.4 bits (215), Expect = 3e-17
Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 2/122 (1%)
Frame = +2
Query: 2 IILYVFFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILDIE 181
+++Y+ F ++ +N R P +DF +T W + + AW G++ +K T P+ + +
Sbjct: 133 LVVYLRFHKLYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMS 192
Query: 182 YC--KSATCTASVNGSYGGLNASLIAGFANIALWAANLWFLFKETLWYERRNPSDQIIGN 355
C + A C+A S G N S++ GF N LWA N WF+FKET W+ + Q
Sbjct: 193 VCHGEEAVCSAGATPSMGLANISVLFGFINFFLWAGNCWFVFKETPWHGQGQDQGQGPSQ 252
Query: 356 ES 361
ES
Sbjct: 253 ES 254
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,845,187
Number of Sequences: 369166
Number of extensions: 1445633
Number of successful extensions: 3243
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3157
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3229
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5733423530
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)