Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_G02
(890 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O15126|SCAM1_HUMAN Secretory carrier-associated membrane... 130 4e-30
sp|Q8K021|SCAM1_MOUSE Secretory carrier-associated membrane... 130 4e-30
sp|P56603|SCAM1_RAT Secretory carrier-associated membrane p... 130 4e-30
sp|O77735|SCAM1_PIG Secretory carrier-associated membrane p... 130 5e-30
sp|O15127|SCAM2_HUMAN Secretory carrier-associated membrane... 120 5e-27
sp|Q58DR5|SCAM3_BOVIN Secretory carrier-associated membrane... 118 2e-26
sp|Q9ERN0|SCAM2_MOUSE Secretory carrier-associated membrane... 117 4e-26
sp|Q9JKD3|SCAM5_MOUSE Secretory carrier-associated membrane... 117 4e-26
sp|Q9JKE3|SCAM5_RAT Secretory carrier-associated membrane p... 117 4e-26
sp|Q8TAC9|SCAM5_HUMAN Secretory carrier-associated membrane... 115 2e-25
>sp|O15126|SCAM1_HUMAN Secretory carrier-associated membrane protein 1 (Secretory carrier
membrane protein 1)
Length = 338
Score = 130 bits (328), Expect = 4e-30
Identities = 67/199 (33%), Positives = 100/199 (50%)
Frame = +3
Query: 171 GSIKNFPPLPSWFPMKPCFYQEIDVEIPAEYRQIVRTGFYIWMAYSVVMLVNIIGTLSYM 350
G N+PPLPS FP+ PCFYQ+ V+IP E+++ V+ +Y+WM ++V + +NI G L++
Sbjct: 115 GRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQKTVKLMYYLWMFHAVTLFLNIFGCLAWF 174
Query: 351 ITQDVXXXXXXXXXXXXXXXXXXVPASYICWFRSLYKAXXXXXXXXXXXXXXXXXAXXXX 530
V P S++CW+R LY A
Sbjct: 175 C---VDSARAVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAV 231
Query: 531 XXXXXXXXXXXXSCGWINSLAELKTSVGVGAFMCIIAGCYTVVLITGSILIFKVHRIYRS 710
+CGWI+SL L ++ VG M IIA +T + ++ KVH +YR+
Sbjct: 232 HVLQAAGFHNWGNCGWISSLTGLNQNIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRT 291
Query: 711 TGASFEKAKAEFSRDLVSN 767
TGASFEKA+ EF+ ++SN
Sbjct: 292 TGASFEKAQQEFATGVMSN 310
>sp|Q8K021|SCAM1_MOUSE Secretory carrier-associated membrane protein 1 (Secretory carrier
membrane protein 1)
Length = 338
Score = 130 bits (328), Expect = 4e-30
Identities = 67/199 (33%), Positives = 100/199 (50%)
Frame = +3
Query: 171 GSIKNFPPLPSWFPMKPCFYQEIDVEIPAEYRQIVRTGFYIWMAYSVVMLVNIIGTLSYM 350
G N+PPLPS FP+ PCFYQ+ V+IP E+++ V+ +Y+WM ++V + +NI G L++
Sbjct: 115 GRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQKTVKLMYYLWMFHAVTLFLNIFGCLAWF 174
Query: 351 ITQDVXXXXXXXXXXXXXXXXXXVPASYICWFRSLYKAXXXXXXXXXXXXXXXXXAXXXX 530
V P S++CW+R LY A
Sbjct: 175 C---VDSSRAVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAV 231
Query: 531 XXXXXXXXXXXXSCGWINSLAELKTSVGVGAFMCIIAGCYTVVLITGSILIFKVHRIYRS 710
+CGWI+SL L ++ VG M IIA +T + ++ KVH +YR+
Sbjct: 232 HVLQAAGFHNWGNCGWISSLTGLNKNIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRT 291
Query: 711 TGASFEKAKAEFSRDLVSN 767
TGASFEKA+ EF+ ++SN
Sbjct: 292 TGASFEKAQQEFATGVMSN 310
>sp|P56603|SCAM1_RAT Secretory carrier-associated membrane protein 1 (Secretory carrier
membrane protein 1) (SCAMP 37)
Length = 338
Score = 130 bits (328), Expect = 4e-30
Identities = 67/199 (33%), Positives = 100/199 (50%)
Frame = +3
Query: 171 GSIKNFPPLPSWFPMKPCFYQEIDVEIPAEYRQIVRTGFYIWMAYSVVMLVNIIGTLSYM 350
G N+PPLPS FP+ PCFYQ+ V+IP E+++ V+ +Y+WM ++V + +NI G L++
Sbjct: 115 GRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQKTVKLMYYLWMFHAVTLFLNIFGCLAWF 174
Query: 351 ITQDVXXXXXXXXXXXXXXXXXXVPASYICWFRSLYKAXXXXXXXXXXXXXXXXXAXXXX 530
V P S++CW+R LY A
Sbjct: 175 C---VDSSRAVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAV 231
Query: 531 XXXXXXXXXXXXSCGWINSLAELKTSVGVGAFMCIIAGCYTVVLITGSILIFKVHRIYRS 710
+CGWI+SL L ++ VG M IIA +T + ++ KVH +YR+
Sbjct: 232 HVLQAAGFHNWGNCGWISSLTGLNKNIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRT 291
Query: 711 TGASFEKAKAEFSRDLVSN 767
TGASFEKA+ EF+ ++SN
Sbjct: 292 TGASFEKAQQEFATGVMSN 310
>sp|O77735|SCAM1_PIG Secretory carrier-associated membrane protein 1 (Secretory carrier
membrane protein 1)
Length = 338
Score = 130 bits (327), Expect = 5e-30
Identities = 67/199 (33%), Positives = 99/199 (49%)
Frame = +3
Query: 171 GSIKNFPPLPSWFPMKPCFYQEIDVEIPAEYRQIVRTGFYIWMAYSVVMLVNIIGTLSYM 350
G N+PPLP FP+ PCFYQ+ V+IP E+++ V+ +Y+WM ++V + +NI G L++
Sbjct: 115 GRKNNWPPLPGNFPVGPCFYQDFSVDIPVEFQKTVKIMYYLWMFHAVTLFLNIFGCLAWF 174
Query: 351 ITQDVXXXXXXXXXXXXXXXXXXVPASYICWFRSLYKAXXXXXXXXXXXXXXXXXAXXXX 530
V P S++CW+R LY A
Sbjct: 175 C---VDPSRGVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAV 231
Query: 531 XXXXXXXXXXXXSCGWINSLAELKTSVGVGAFMCIIAGCYTVVLITGSILIFKVHRIYRS 710
+CGWI+SL L S+ VG M IIA +T + ++ KVH +YR+
Sbjct: 232 HVLQAAGFHNWGNCGWISSLTGLNQSIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRT 291
Query: 711 TGASFEKAKAEFSRDLVSN 767
TGASFEKA+ EF+ ++SN
Sbjct: 292 TGASFEKAQQEFATGVMSN 310
>sp|O15127|SCAM2_HUMAN Secretory carrier-associated membrane protein 2 (Secretory carrier
membrane protein 2)
Length = 329
Score = 120 bits (301), Expect = 5e-27
Identities = 59/196 (30%), Positives = 98/196 (50%), Gaps = 1/196 (0%)
Frame = +3
Query: 183 NFPPLPSWFPMKPCFYQEIDVEIPAEYRQIVRTGFYIWMAYSVVMLVNIIGTLSYMITQD 362
N+PPLPSW P+KPCFYQ+ EIPA+Y++I + +Y+WM +SV + +N++ L++
Sbjct: 119 NWPPLPSWCPVKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFSGNS 178
Query: 363 VXXXXXXXXXXXXXXXXXXVPASYICWFRSLYKAXXXXXXXXXXXXXXXXXAXXXXXXXX 542
P +++CW+R +YKA
Sbjct: 179 ---SKGVDFGLSILWFLIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYIIQ 235
Query: 543 XXXXXXXXSCGWINSLAELKT-SVGVGAFMCIIAGCYTVVLITGSILIFKVHRIYRSTGA 719
GWI +L+ L S+ + M ++AG +T+ + L+ +VH +YR TGA
Sbjct: 236 LVGIPGLGDSGWIAALSTLDNHSLAISVIMMVVAGFFTLCAVLSVFLLQRVHSLYRRTGA 295
Query: 720 SFEKAKAEFSRDLVSN 767
SF++A+ EFS+ + S+
Sbjct: 296 SFQQAQEEFSQGIFSS 311
>sp|Q58DR5|SCAM3_BOVIN Secretory carrier-associated membrane protein 3 (Secretory carrier
membrane protein 3)
Length = 347
Score = 118 bits (296), Expect = 2e-26
Identities = 58/195 (29%), Positives = 98/195 (50%)
Frame = +3
Query: 183 NFPPLPSWFPMKPCFYQEIDVEIPAEYRQIVRTGFYIWMAYSVVMLVNIIGTLSYMITQD 362
N+PPLPS+ P++PCF+Q+I +EIP E+++ V T +Y+WM ++ +L+N + L+
Sbjct: 134 NWPPLPSFCPVQPCFFQDISMEIPQEFQKTVSTMYYLWMCSTLALLLNFLACLASFC--- 190
Query: 363 VXXXXXXXXXXXXXXXXXXVPASYICWFRSLYKAXXXXXXXXXXXXXXXXXAXXXXXXXX 542
V P S++CW+R +YKA
Sbjct: 191 VETSNGSGFGLSILWILLFTPCSFVCWYRPMYKAFRSDSSSNFFVFFFIFFVQDVLFVLQ 250
Query: 543 XXXXXXXXSCGWINSLAELKTSVGVGAFMCIIAGCYTVVLITGSILIFKVHRIYRSTGAS 722
GWI++L LK + V M ++A +T + + G +++ ++H +YR TGAS
Sbjct: 251 AIGIPGWGFSGWISALVVLKVNTAVAVLMLLVALFFTGIAVLGIVMLKRIHSLYRRTGAS 310
Query: 723 FEKAKAEFSRDLVSN 767
F+KA+ EF+ + SN
Sbjct: 311 FQKAQQEFAAGVFSN 325
>sp|Q9ERN0|SCAM2_MOUSE Secretory carrier-associated membrane protein 2 (Secretory carrier
membrane protein 2)
Length = 329
Score = 117 bits (293), Expect = 4e-26
Identities = 60/196 (30%), Positives = 99/196 (50%), Gaps = 1/196 (0%)
Frame = +3
Query: 183 NFPPLPSWFPMKPCFYQEIDVEIPAEYRQIVRTGFYIWMAYSVVMLVNIIGTLSYMITQD 362
N+PPLPSW P+KPCFYQ+ EIPA+Y++I + +Y+WM +SV + +N++ L++ T D
Sbjct: 119 NWPPLPSWCPVKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAW-FTSD 177
Query: 363 VXXXXXXXXXXXXXXXXXXVPASYICWFRSLYKAXXXXXXXXXXXXXXXXXAXXXXXXXX 542
P +++CW+R +YKA
Sbjct: 178 A--ANGTAFGLSILWFLIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYFIQ 235
Query: 543 XXXXXXXXSCGWINSLAELKTS-VGVGAFMCIIAGCYTVVLITGSILIFKVHRIYRSTGA 719
+ GW+ +L+ +K + V M ++AG +T+ L+ +VH YR TGA
Sbjct: 236 LIGLPNLGTSGWLAALSTMKNGPLAVTIIMMVVAGFFTLCAGLSLFLLQRVHAFYRRTGA 295
Query: 720 SFEKAKAEFSRDLVSN 767
SF++A+ EFS+ + S+
Sbjct: 296 SFQQAQEEFSQGIFSS 311
>sp|Q9JKD3|SCAM5_MOUSE Secretory carrier-associated membrane protein 5 (Secretory carrier
membrane protein 5)
Length = 235
Score = 117 bits (293), Expect = 4e-26
Identities = 58/191 (30%), Positives = 91/191 (47%)
Frame = +3
Query: 177 IKNFPPLPSWFPMKPCFYQEIDVEIPAEYRQIVRTGFYIWMAYSVVMLVNIIGTLSYMIT 356
+ NFPPLP + P+KPCFYQ+ + +IP ++ + + +Y+WM SV + VN++G L+++I
Sbjct: 5 VNNFPPLPKFIPLKPCFYQDFEADIPPQHLSLTKRLYYLWMLNSVTLAVNLVGCLAWLI- 63
Query: 357 QDVXXXXXXXXXXXXXXXXXXVPASYICWFRSLYKAXXXXXXXXXXXXXXXXXAXXXXXX 536
P SY+CWFR +YKA A
Sbjct: 64 ---GGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI 120
Query: 537 XXXXXXXXXXSCGWINSLAELKTSVGVGAFMCIIAGCYTVVLITGSILIFKVHRIYRSTG 716
CGWI +++ T++G M I +TVV + I + VH+ YR +G
Sbjct: 121 IQAVGIPGWGVCGWIATISFFGTNIGSAVVMLIPTVMFTVVAVFSFIALSMVHKFYRGSG 180
Query: 717 ASFEKAKAEFS 749
SF KA+ E++
Sbjct: 181 GSFSKAQEEWT 191
>sp|Q9JKE3|SCAM5_RAT Secretory carrier-associated membrane protein 5 (Secretory carrier
membrane protein 5)
Length = 235
Score = 117 bits (293), Expect = 4e-26
Identities = 58/191 (30%), Positives = 91/191 (47%)
Frame = +3
Query: 177 IKNFPPLPSWFPMKPCFYQEIDVEIPAEYRQIVRTGFYIWMAYSVVMLVNIIGTLSYMIT 356
+ NFPPLP + P+KPCFYQ+ + +IP ++ + + +Y+WM SV + VN++G L+++I
Sbjct: 5 VNNFPPLPKFIPLKPCFYQDFEADIPPQHLSLTKRLYYLWMLNSVTLAVNLVGCLAWLI- 63
Query: 357 QDVXXXXXXXXXXXXXXXXXXVPASYICWFRSLYKAXXXXXXXXXXXXXXXXXAXXXXXX 536
P SY+CWFR +YKA A
Sbjct: 64 ---GGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI 120
Query: 537 XXXXXXXXXXSCGWINSLAELKTSVGVGAFMCIIAGCYTVVLITGSILIFKVHRIYRSTG 716
CGWI +++ T++G M I +TVV + I + VH+ YR +G
Sbjct: 121 IQAVGIPGWGVCGWIATISFFGTNIGSAVVMLIPTVMFTVVAVFSFIALSMVHKFYRGSG 180
Query: 717 ASFEKAKAEFS 749
SF KA+ E++
Sbjct: 181 GSFSKAQEEWT 191
>sp|Q8TAC9|SCAM5_HUMAN Secretory carrier-associated membrane protein 5 (Secretory carrier
membrane protein 5)
Length = 235
Score = 115 bits (288), Expect = 2e-25
Identities = 57/191 (29%), Positives = 91/191 (47%)
Frame = +3
Query: 177 IKNFPPLPSWFPMKPCFYQEIDVEIPAEYRQIVRTGFYIWMAYSVVMLVNIIGTLSYMIT 356
+ NFPPLP + P+KPCFYQ+ + +IP ++ + + +Y+WM SV + VN++G L+++I
Sbjct: 5 VNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLAWLI- 63
Query: 357 QDVXXXXXXXXXXXXXXXXXXVPASYICWFRSLYKAXXXXXXXXXXXXXXXXXAXXXXXX 536
P SY+CWFR +YKA A
Sbjct: 64 ---GGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISI 120
Query: 537 XXXXXXXXXXSCGWINSLAELKTSVGVGAFMCIIAGCYTVVLITGSILIFKVHRIYRSTG 716
CGWI +++ T++G M I +TV+ + I + VH+ YR +G
Sbjct: 121 IQAVGIPGWGVCGWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSG 180
Query: 717 ASFEKAKAEFS 749
SF KA+ E++
Sbjct: 181 GSFSKAQEEWT 191
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,334,248
Number of Sequences: 369166
Number of extensions: 1403022
Number of successful extensions: 3506
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3397
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3476
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8934348180
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)