Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_D24
(460 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q07816|BCLX_CHICK Apoptosis regulator Bcl-X (Bcl-2-like ... 75 5e-14
sp|O77737|BCLX_PIG Apoptosis regulator Bcl-X (Bcl-2-like 1 ... 73 3e-13
sp|P53563|BCLX_RAT Apoptosis regulator Bcl-X (Bcl-2-like 1 ... 72 5e-13
sp|Q64373|BCLX_MOUSE Apoptosis regulator Bcl-X (Bcl-2-like ... 72 5e-13
sp|Q07817|BCLX_HUMAN Apoptosis regulator Bcl-X (Bcl-2-like ... 72 6e-13
sp|Q00709|BCL2_CHICK Apoptosis regulator Bcl-2 70 3e-12
sp|Q91827|AR1_XENLA Apoptosis regulator R1 (XR1) 69 4e-12
sp|P10415|BCL2_HUMAN Apoptosis regulator Bcl-2 67 2e-11
sp|Q91828|AR11_XENLA Apoptosis regulator R11 (XR11) 67 2e-11
sp|Q9JJV8|BCL2_CRIGR Apoptosis regulator Bcl-2 66 4e-11
>sp|Q07816|BCLX_CHICK Apoptosis regulator Bcl-X (Bcl-2-like 1 protein)
Length = 229
Score = 75.5 bits (184), Expect = 5e-14
Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 1/122 (0%)
Frame = +3
Query: 24 NDILNKLTDKSDEFERQYYPRFENRKSLLEKIPERAFLDFIDTLHGIFEDNQINWGRIIG 203
+D+ L D DEFE +Y F + S L P A+ F ++ +F D +NWGRI+
Sbjct: 80 SDVRQALRDAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFHDG-VNWGRIVA 138
Query: 204 YFTFVGSYCTACIEHGMVRIVYNLVEYAIKYMNTNLSGWMSSNGGW-RGLGLALSTESFE 380
+F+F G+ C ++ M +V +V + Y+ +L W+ NGGW R + L + + E
Sbjct: 139 FFSFGGALCVESVDKEMRVLVGRIVSWMTTYLTDHLDPWIQENGGWERFVDLYGNNAAAE 198
Query: 381 LR 386
LR
Sbjct: 199 LR 200
>sp|O77737|BCLX_PIG Apoptosis regulator Bcl-X (Bcl-2-like 1 protein)
Length = 233
Score = 73.2 bits (178), Expect = 3e-13
Identities = 34/100 (34%), Positives = 53/100 (53%)
Frame = +3
Query: 42 LTDKSDEFERQYYPRFENRKSLLEKIPERAFLDFIDTLHGIFEDNQINWGRIIGYFTFVG 221
L + DEFE +Y F + S L P A+ F L+ +F D +NWGRI+ +F+F G
Sbjct: 90 LREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVLNELFRDG-VNWGRIVAFFSFGG 148
Query: 222 SYCTACIEHGMVRIVYNLVEYAIKYMNTNLSGWMSSNGGW 341
+ C ++ M +V + + Y+N +L W+ NGGW
Sbjct: 149 ALCVESVDKEMQVLVSRIATWMATYLNDHLEPWIQENGGW 188
>sp|P53563|BCLX_RAT Apoptosis regulator Bcl-X (Bcl-2-like 1 protein)
Length = 233
Score = 72.4 bits (176), Expect = 5e-13
Identities = 33/100 (33%), Positives = 53/100 (53%)
Frame = +3
Query: 42 LTDKSDEFERQYYPRFENRKSLLEKIPERAFLDFIDTLHGIFEDNQINWGRIIGYFTFVG 221
L + DEFE +Y F + S L P A+ F ++ +F D +NWGRI+ +F+F G
Sbjct: 90 LREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVAFFSFGG 148
Query: 222 SYCTACIEHGMVRIVYNLVEYAIKYMNTNLSGWMSSNGGW 341
+ C ++ M +V + + Y+N +L W+ NGGW
Sbjct: 149 ALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGW 188
>sp|Q64373|BCLX_MOUSE Apoptosis regulator Bcl-X (Bcl-2-like 1 protein)
Length = 233
Score = 72.4 bits (176), Expect = 5e-13
Identities = 33/100 (33%), Positives = 53/100 (53%)
Frame = +3
Query: 42 LTDKSDEFERQYYPRFENRKSLLEKIPERAFLDFIDTLHGIFEDNQINWGRIIGYFTFVG 221
L + DEFE +Y F + S L P A+ F ++ +F D +NWGRI+ +F+F G
Sbjct: 90 LREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVAFFSFGG 148
Query: 222 SYCTACIEHGMVRIVYNLVEYAIKYMNTNLSGWMSSNGGW 341
+ C ++ M +V + + Y+N +L W+ NGGW
Sbjct: 149 ALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGW 188
>sp|Q07817|BCLX_HUMAN Apoptosis regulator Bcl-X (Bcl-2-like 1 protein)
Length = 233
Score = 72.0 bits (175), Expect = 6e-13
Identities = 33/100 (33%), Positives = 53/100 (53%)
Frame = +3
Query: 42 LTDKSDEFERQYYPRFENRKSLLEKIPERAFLDFIDTLHGIFEDNQINWGRIIGYFTFVG 221
L + DEFE +Y F + S L P A+ F ++ +F D +NWGRI+ +F+F G
Sbjct: 90 LREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVAFFSFGG 148
Query: 222 SYCTACIEHGMVRIVYNLVEYAIKYMNTNLSGWMSSNGGW 341
+ C ++ M +V + + Y+N +L W+ NGGW
Sbjct: 149 ALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGW 188
>sp|Q00709|BCL2_CHICK Apoptosis regulator Bcl-2
Length = 233
Score = 69.7 bits (169), Expect = 3e-12
Identities = 33/100 (33%), Positives = 48/100 (48%)
Frame = +3
Query: 42 LTDKSDEFERQYYPRFENRKSLLEKIPERAFLDFIDTLHGIFEDNQINWGRIIGYFTFVG 221
L DEF R+Y F L P A F+ + +F D +NWGRI+ +F F G
Sbjct: 91 LRQAGDEFSRRYQRDFAQMSGQLHLTPFTAHGRFVAVVEELFRDG-VNWGRIVAFFEFGG 149
Query: 222 SYCTACIEHGMVRIVYNLVEYAIKYMNTNLSGWMSSNGGW 341
C + M +V N+ + +Y+N +L W+ NGGW
Sbjct: 150 VMCVESVNREMSPLVDNIATWMTEYLNRHLHNWIQDNGGW 189
>sp|Q91827|AR1_XENLA Apoptosis regulator R1 (XR1)
Length = 228
Score = 69.3 bits (168), Expect = 4e-12
Identities = 29/97 (29%), Positives = 50/97 (51%)
Frame = +3
Query: 57 DEFERQYYPRFENRKSLLEKIPERAFLDFIDTLHGIFEDNQINWGRIIGYFTFVGSYCTA 236
DEFE ++ F + + P A+ F + +F+ +NWGRI+ +F F + C
Sbjct: 86 DEFEERFRQAFSEISTQIHVTPGTAYARFAEVAGSLFQGG-VNWGRIVAFFVFGAALCAE 144
Query: 237 CIEHGMVRIVYNLVEYAIKYMNTNLSGWMSSNGGWRG 347
+ M ++ + ++ + Y+ TNL W+ SNGGW G
Sbjct: 145 SVNKEMSPLLPRIQDWMVTYLETNLRDWIQSNGGWNG 181
>sp|P10415|BCL2_HUMAN Apoptosis regulator Bcl-2
Length = 239
Score = 66.6 bits (161), Expect = 2e-11
Identities = 35/109 (32%), Positives = 51/109 (46%)
Frame = +3
Query: 15 PVTNDILNKLTDKSDEFERQYYPRFENRKSLLEKIPERAFLDFIDTLHGIFEDNQINWGR 194
PV + L D+F R+Y F S L P A F + +F D +NWGR
Sbjct: 88 PVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDG-VNWGR 146
Query: 195 IIGYFTFVGSYCTACIEHGMVRIVYNLVEYAIKYMNTNLSGWMSSNGGW 341
I+ +F F G C + M +V N+ + +Y+N +L W+ NGGW
Sbjct: 147 IVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGW 195
>sp|Q91828|AR11_XENLA Apoptosis regulator R11 (XR11)
Length = 204
Score = 66.6 bits (161), Expect = 2e-11
Identities = 32/108 (29%), Positives = 53/108 (49%)
Frame = +3
Query: 18 VTNDILNKLTDKSDEFERQYYPRFENRKSLLEKIPERAFLDFIDTLHGIFEDNQINWGRI 197
V ++L L + ++EFE +Y F + S L + A F + +F D NWGRI
Sbjct: 54 VEEEVLQALLEATEEFELRYQRAFSDLTSQLHITQDTAQQSFQQVMGELFRDGT-NWGRI 112
Query: 198 IGYFTFVGSYCTACIEHGMVRIVYNLVEYAIKYMNTNLSGWMSSNGGW 341
+ +F+F + C M ++ +V++ + Y+ L WM NGGW
Sbjct: 113 VAFFSFGRALCVESANKEMTDLLPRIVQWMVNYLEHTLQPWMQENGGW 160
>sp|Q9JJV8|BCL2_CRIGR Apoptosis regulator Bcl-2
Length = 236
Score = 65.9 bits (159), Expect = 4e-11
Identities = 35/109 (32%), Positives = 51/109 (46%)
Frame = +3
Query: 15 PVTNDILNKLTDKSDEFERQYYPRFENRKSLLEKIPERAFLDFIDTLHGIFEDNQINWGR 194
PV + L D+F R+Y F S L P A F + +F D +NWGR
Sbjct: 85 PVPPVVHLTLRRAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDG-VNWGR 143
Query: 195 IIGYFTFVGSYCTACIEHGMVRIVYNLVEYAIKYMNTNLSGWMSSNGGW 341
I+ +F F G C + M +V N+ + +Y+N +L W+ NGGW
Sbjct: 144 IVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGW 192
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,644,497
Number of Sequences: 369166
Number of extensions: 966411
Number of successful extensions: 2496
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2419
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2477
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2534533995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)