Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_D16
(543 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P18489|SYB_DROME Synaptobrevin 78 2e-14
sp|P47193|VAMP2_XENLA Vesicle-associated membrane protein 2... 74 2e-13
sp|P63026|VAMP2_BOVIN Vesicle-associated membrane protein 2... 74 3e-13
sp|P63045|VAMP2_RAT Vesicle-associated membrane protein 2 (... 74 3e-13
sp|P47194|SYB_LOLPE Synaptobrevin 73 4e-13
sp|Q15836|VAM3_HUMAN Vesicle-associated membrane protein 3 ... 72 9e-13
sp|P63025|VAMP3_RAT Vesicle-associated membrane protein 3 (... 72 9e-13
sp|Q62442|VAMP1_MOUSE Vesicle-associated membrane protein 1... 72 1e-12
sp|P23763|VAM1_HUMAN Vesicle-associated membrane protein 1 ... 70 3e-12
sp|P13701|SYB_TORCA Synaptobrevin (Synaptic vesicle-associa... 70 3e-12
>sp|P18489|SYB_DROME Synaptobrevin
Length = 152
Score = 77.8 bits (190), Expect = 2e-14
Identities = 40/87 (45%), Positives = 55/87 (63%)
Frame = +1
Query: 121 NQFNTYSQYHAVNVKGEDTQKTKLQKTQEEVDVVVQQMKENVHKVLIRDSKLHDLHIRAD 300
N + Y+Q+ ++ + + KLQ+TQ +VD VV M+ NV KVL RD KL +L RAD
Sbjct: 25 NANDNYNQFGDHQIRNNNAAQKKLQQTQAKVDEVVGIMRVNVEKVLERDQKLSELGERAD 84
Query: 301 ELTEGANQFXXXXRKVKRKFWWQNKKM 381
+L +GA+QF K+KRK WW N KM
Sbjct: 85 QLEQGASQFEQQAGKLKRKQWWANMKM 111
>sp|P47193|VAMP2_XENLA Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
(SYBII)
Length = 114
Score = 74.3 bits (181), Expect = 2e-13
Identities = 37/69 (53%), Positives = 47/69 (68%)
Frame = +1
Query: 175 TQKTKLQKTQEEVDVVVQQMKENVHKVLIRDSKLHDLHIRADELTEGANQFXXXXRKVKR 354
T +LQ+TQ +VD VV M+ NV KVL RD+KL +L RAD L GA+QF K+KR
Sbjct: 25 TSNRRLQQTQAQVDEVVDIMRVNVDKVLERDTKLSELDDRADALQAGASQFETSAAKLKR 84
Query: 355 KFWWQNKKM 381
K+WW+N KM
Sbjct: 85 KYWWKNMKM 93
>sp|P63026|VAMP2_BOVIN Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
sp|P63027|VAM2_HUMAN Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin 2)
Length = 116
Score = 73.6 bits (179), Expect = 3e-13
Identities = 37/69 (53%), Positives = 46/69 (66%)
Frame = +1
Query: 175 TQKTKLQKTQEEVDVVVQQMKENVHKVLIRDSKLHDLHIRADELTEGANQFXXXXRKVKR 354
T +LQ+TQ +VD VV M+ NV KVL RD KL +L RAD L GA+QF K+KR
Sbjct: 27 TSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKR 86
Query: 355 KFWWQNKKM 381
K+WW+N KM
Sbjct: 87 KYWWKNLKM 95
>sp|P63045|VAMP2_RAT Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
sp|P63044|VAMP2_MOUSE Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Length = 116
Score = 73.6 bits (179), Expect = 3e-13
Identities = 37/69 (53%), Positives = 46/69 (66%)
Frame = +1
Query: 175 TQKTKLQKTQEEVDVVVQQMKENVHKVLIRDSKLHDLHIRADELTEGANQFXXXXRKVKR 354
T +LQ+TQ +VD VV M+ NV KVL RD KL +L RAD L GA+QF K+KR
Sbjct: 27 TSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKR 86
Query: 355 KFWWQNKKM 381
K+WW+N KM
Sbjct: 87 KYWWKNLKM 95
>sp|P47194|SYB_LOLPE Synaptobrevin
Length = 125
Score = 73.2 bits (178), Expect = 4e-13
Identities = 37/68 (54%), Positives = 47/68 (69%)
Frame = +1
Query: 178 QKTKLQKTQEEVDVVVQQMKENVHKVLIRDSKLHDLHIRADELTEGANQFXXXXRKVKRK 357
Q +LQ+TQ +V+ VV M+ NV KVL RDSK+ +L RAD L GA+QF K+KRK
Sbjct: 37 QSKRLQQTQAQVEEVVDIMRVNVDKVLERDSKISELDDRADALQAGASQFEASAGKLKRK 96
Query: 358 FWWQNKKM 381
FWW+N KM
Sbjct: 97 FWWKNCKM 104
>sp|Q15836|VAM3_HUMAN Vesicle-associated membrane protein 3 (VAMP-3) (Synaptobrevin 3)
(Cellubrevin) (CEB)
Length = 100
Score = 72.0 bits (175), Expect = 9e-13
Identities = 36/65 (55%), Positives = 45/65 (69%)
Frame = +1
Query: 187 KLQKTQEEVDVVVQQMKENVHKVLIRDSKLHDLHIRADELTEGANQFXXXXRKVKRKFWW 366
+LQ+TQ +VD VV M+ NV KVL RD KL +L RAD L GA+QF K+KRK+WW
Sbjct: 14 RLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWW 73
Query: 367 QNKKM 381
+N KM
Sbjct: 74 KNCKM 78
>sp|P63025|VAMP3_RAT Vesicle-associated membrane protein 3 (VAMP-3) (Synaptobrevin-3)
(Cellubrevin) (CEB)
sp|P63024|VAMP3_MOUSE Vesicle-associated membrane protein 3 (VAMP-3) (Synaptobrevin-3)
(Cellubrevin) (CEB)
Length = 103
Score = 72.0 bits (175), Expect = 9e-13
Identities = 36/65 (55%), Positives = 45/65 (69%)
Frame = +1
Query: 187 KLQKTQEEVDVVVQQMKENVHKVLIRDSKLHDLHIRADELTEGANQFXXXXRKVKRKFWW 366
+LQ+TQ +VD VV M+ NV KVL RD KL +L RAD L GA+QF K+KRK+WW
Sbjct: 18 RLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWW 77
Query: 367 QNKKM 381
+N KM
Sbjct: 78 KNCKM 82
>sp|Q62442|VAMP1_MOUSE Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin-1)
Length = 118
Score = 71.6 bits (174), Expect = 1e-12
Identities = 36/69 (52%), Positives = 46/69 (66%)
Frame = +1
Query: 175 TQKTKLQKTQEEVDVVVQQMKENVHKVLIRDSKLHDLHIRADELTEGANQFXXXXRKVKR 354
T +LQ+TQ +V+ VV M+ NV KVL RD KL +L RAD L GA+QF K+KR
Sbjct: 29 TSNRRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKR 88
Query: 355 KFWWQNKKM 381
K+WW+N KM
Sbjct: 89 KYWWKNCKM 97
>sp|P23763|VAM1_HUMAN Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin 1)
Length = 118
Score = 70.1 bits (170), Expect = 3e-12
Identities = 35/69 (50%), Positives = 46/69 (66%)
Frame = +1
Query: 175 TQKTKLQKTQEEVDVVVQQMKENVHKVLIRDSKLHDLHIRADELTEGANQFXXXXRKVKR 354
T +LQ+TQ +V+ VV ++ NV KVL RD KL +L RAD L GA+QF K+KR
Sbjct: 29 TSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKR 88
Query: 355 KFWWQNKKM 381
K+WW+N KM
Sbjct: 89 KYWWKNCKM 97
>sp|P13701|SYB_TORCA Synaptobrevin (Synaptic vesicle-associated integral membrane
protein) (VAMP-1)
Length = 120
Score = 70.1 bits (170), Expect = 3e-12
Identities = 35/69 (50%), Positives = 46/69 (66%)
Frame = +1
Query: 175 TQKTKLQKTQEEVDVVVQQMKENVHKVLIRDSKLHDLHIRADELTEGANQFXXXXRKVKR 354
T +LQ+TQ +V+ VV ++ NV KVL RD KL +L RAD L GA+QF K+KR
Sbjct: 31 TSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKR 90
Query: 355 KFWWQNKKM 381
K+WW+N KM
Sbjct: 91 KYWWKNCKM 99
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,451,516
Number of Sequences: 369166
Number of extensions: 665793
Number of successful extensions: 2982
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2944
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2980
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3734833040
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)