Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_D07
(887 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P18899|DDR48_YEAST Stress protein DDR48 (DNA damage-resp... 42 0.002
sp|P13824|ARP2_PLAFA Clustered-asparagine-rich protein (CARP) 40 0.007
sp|Q15056|IF4H_HUMAN Eukaryotic translation initiation fact... 40 0.011
sp|Q9WUK2|IF4H_MOUSE Eukaryotic translation initiation fact... 39 0.019
sp|Q88VK7|IF2_LACPL Translation initiation factor IF-2 39 0.025
sp|O43952|TGP1_TETTH G-quartet DNA binding protein TGP1 39 0.025
sp|P14196|AAC2_DICDI AAC-rich mRNA clone AAC11 protein 38 0.033
sp|P38922|HRB1_YEAST Protein HRB1 (Protein TOM34) 37 0.056
sp|Q69154|IE63_MCMVS Transcriptional regulator IE63 homolog... 37 0.056
sp|O74786|SEC9_SCHPO Protein transport protein sec9 37 0.074
>sp|P18899|DDR48_YEAST Stress protein DDR48 (DNA damage-responsive protein 48) (DDRP 48)
(YP 75) (Flocculent-specific protein)
Length = 430
Score = 42.0 bits (97), Expect = 0.002
Identities = 26/104 (25%), Positives = 48/104 (46%)
Frame = +1
Query: 10 HEGFAQNTNDTHYEMINRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTRN 189
++ + N ND+ Y N +Y ++ +S+ G+N +NN+ Y + YG+ N
Sbjct: 101 NDSYGSNNNDS-YGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNNDSYGSNN 159
Query: 190 RGNYSANRGNYCQESRLRNDSERSVGSSNGAKSNSLQEMGYSNS 321
+Y +N + S N ++ S GS+N S + Y +S
Sbjct: 160 NDSYGSNNDDSYGSS---NKNKSSYGSNNDDSYGSNNDDSYGSS 200
Score = 37.4 bits (85), Expect = 0.056
Identities = 25/93 (26%), Positives = 47/93 (50%)
Frame = +1
Query: 13 EGFAQNTNDTHYEMINRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTRNR 192
+ + N ND+ Y N +Y ++ +S+ G+N +NN+ Y + YG+ N+
Sbjct: 221 DSYGSNNNDS-YGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNDDSYGSSNK 279
Query: 193 GNYSANRGNYCQESRLRNDSERSVGSSNGAKSN 291
N S+ + +S ++++ S GSSN KS+
Sbjct: 280 -NKSSYGSSSNDDSYGSSNNDDSYGSSNKKKSS 311
Score = 36.2 bits (82), Expect = 0.13
Identities = 23/88 (26%), Positives = 40/88 (45%)
Frame = +1
Query: 28 NTNDTHYEMINRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTRNRGNYSA 207
++N+ Y N +Y ++ +S+ G+N +NN+ Y + YG+ NR S
Sbjct: 340 SSNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNNDDSYGSSNRNKNSY 399
Query: 208 NRGNYCQESRLRNDSERSVGSSNGAKSN 291
NY ++++ S GSSN N
Sbjct: 400 GSSNYGS-----SNNDDSYGSSNRGGRN 422
Score = 33.1 bits (74), Expect = 1.1
Identities = 23/105 (21%), Positives = 40/105 (38%), Gaps = 5/105 (4%)
Frame = +1
Query: 22 AQNTNDTHYEMINRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTRNRGNY 201
+ N ND++ N + + + S N Y + N + Y + YG+ N +Y
Sbjct: 140 SSNNNDSYGS--NNNDSYGSNNNDSYGSNNDDSYGSSNKNKSSYGSNNDDSYGSNNDDSY 197
Query: 202 SANRGNYCQESRLRNDS-----ERSVGSSNGAKSNSLQEMGYSNS 321
++ NDS + S GS+N S + Y +S
Sbjct: 198 GSSNKKKSSYGSSNNDSYGSNNDDSYGSNNNDSYGSNNDDSYGSS 242
Score = 32.3 bits (72), Expect = 1.8
Identities = 22/97 (22%), Positives = 40/97 (41%)
Frame = +1
Query: 28 NTNDTHYEMINRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTRNRGNYSA 207
+ ND Y N +Y ++ +S+ G++ NN+ Y + YG+ N +Y +
Sbjct: 183 SNNDDSYGSNNDDSYGSSNKKKSSYGSS---------NNDSYGSNNDDSYGSNNNDSYGS 233
Query: 208 NRGNYCQESRLRNDSERSVGSSNGAKSNSLQEMGYSN 318
N + S + S S + SN+ G +N
Sbjct: 234 NNDDSYGSSNKKKSSYGSNNDDSYGSSNNNDSYGSNN 270
Score = 30.8 bits (68), Expect = 5.3
Identities = 27/123 (21%), Positives = 47/123 (38%), Gaps = 20/123 (16%)
Frame = +1
Query: 13 EGFAQNTNDTHYEMINRGNYFAARGGRSNRGT-----------NQHQYKTDKHNNNQYND 159
+ + + N+ Y N +Y ++ +S+ G+ N Y + + Y
Sbjct: 255 DSYGSSNNNDSYGSNNDDSYGSSNKNKSSYGSSSNDDSYGSSNNDDSYGSSNKKKSSYGS 314
Query: 160 AFRNYYGTRNRGNYSANRGNYCQESRLRNDS-----ERSVGSSNGAK----SNSLQEMGY 312
+ YG+ N +Y ++ NDS + S GSSN K SN+ G
Sbjct: 315 NNDDSYGSNNDDSYGSSNKKKSSYGSSNNDSYGSNNDDSYGSSNKKKSSYGSNNDDSYGS 374
Query: 313 SNS 321
SN+
Sbjct: 375 SNN 377
>sp|P13824|ARP2_PLAFA Clustered-asparagine-rich protein (CARP)
Length = 443
Score = 40.4 bits (93), Expect = 0.007
Identities = 23/98 (23%), Positives = 47/98 (47%)
Frame = +1
Query: 28 NTNDTHYEMINRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTRNRGNYSA 207
N ++T ++ N N ++G +N G+N + + + NNN N F N + N N
Sbjct: 117 NNSNTFFQKNNMNNTNFSQGS-TNYGSN-YNSENFQGNNNMNNYNFYNNNSSNNNNNNQT 174
Query: 208 NRGNYCQESRLRNDSERSVGSSNGAKSNSLQEMGYSNS 321
N N ++N + + ++N + +N + M ++N+
Sbjct: 175 NTQNNFMNRNMKNKNMNNNNNNNNSNNNMMMNMNFNNN 212
Score = 30.0 bits (66), Expect = 9.0
Identities = 23/107 (21%), Positives = 42/107 (39%), Gaps = 8/107 (7%)
Frame = +1
Query: 25 QNTNDTHYEMINRGNYFAARGGRSNRGTNQHQYKT----DKHNNNQYNDAFRNY---YGT 183
+N DT E N FA N N + T + NN ++ NY Y +
Sbjct: 87 KNLIDTSGEERNIDAKFAVPNVSINNNNNNNNSNTFFQKNNMNNTNFSQGSTNYGSNYNS 146
Query: 184 RN-RGNYSANRGNYCQESRLRNDSERSVGSSNGAKSNSLQEMGYSNS 321
N +GN + N N+ + N++ + N + +++ +N+
Sbjct: 147 ENFQGNNNMNNYNFYNNNSSNNNNNNQTNTQNNFMNRNMKNKNMNNN 193
>sp|Q15056|IF4H_HUMAN Eukaryotic translation initiation factor 4H (eIF-4H)
(Williams-Beuren syndrome chromosome region 1 protein)
Length = 248
Score = 39.7 bits (91), Expect = 0.011
Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 2/138 (1%)
Frame = +1
Query: 58 NRGNYFAARGGRSNRGT-NQHQYKTDKHNNNQYNDAFRN-YYGTRNRGNYSANRGNYCQE 231
++G + +GG +RG + + + + + +N FR+ + G R R
Sbjct: 122 DKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPMG 181
Query: 232 SRLRNDSERSVGSSNGAKSNSLQEMGYSNSATAQKDRPKLRLLPRSIDAPLNEQIHSERT 411
SR R D GS+ + + +E + RP+L+L PR++ PLN+ +
Sbjct: 182 SRFR-DGPPLRGSNMDFREPTEEE---------RAQRPRLQLKPRTVATPLNQV--ANPN 229
Query: 412 AAIFGKGKpreASPVREK 465
+AIFG +pre +E+
Sbjct: 230 SAIFGGARpreEVVQKEQ 247
>sp|Q9WUK2|IF4H_MOUSE Eukaryotic translation initiation factor 4H (eIF-4H)
(Williams-Beuren syndrome chromosome region 1 protein
homolog)
Length = 248
Score = 38.9 bits (89), Expect = 0.019
Identities = 34/138 (24%), Positives = 62/138 (44%), Gaps = 2/138 (1%)
Frame = +1
Query: 58 NRGNYFAARGGRSNRGTN-QHQYKTDKHNNNQYNDAFRN-YYGTRNRGNYSANRGNYCQE 231
++G + +GG +RG + + + + +N +R+ + G R R
Sbjct: 122 DKGGFGFRKGGPDDRGMGGSRESRGGWDSRDDFNSGYRDDFLGGRGGSRPGDRRAGPPMG 181
Query: 232 SRLRNDSERSVGSSNGAKSNSLQEMGYSNSATAQKDRPKLRLLPRSIDAPLNEQIHSERT 411
SR R D GS+ + + +E + RP+L+L PR++ PLN+ +
Sbjct: 182 SRFR-DGPPLRGSNMDFREPTEEE---------RAQRPRLQLKPRTVATPLNQV--ANPN 229
Query: 412 AAIFGKGKpreASPVREK 465
+AIFG +pre +E+
Sbjct: 230 SAIFGGARpreEVVQKEQ 247
>sp|Q88VK7|IF2_LACPL Translation initiation factor IF-2
Length = 858
Score = 38.5 bits (88), Expect = 0.025
Identities = 27/94 (28%), Positives = 41/94 (43%)
Frame = +1
Query: 7 RHEGFAQNTNDTHYEMINRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTR 186
RH+ N+ N + G RSN G N +T+ +N N+ +A R+ R
Sbjct: 87 RHQQSGDYLNNNRNNNQNNSQSRNSNGNRSNNGGN----RTNSNNGNRSANASRS-NSAR 141
Query: 187 NRGNYSANRGNYCQESRLRNDSERSVGSSNGAKS 288
N G + NR N + N++ RS S+N S
Sbjct: 142 NNGGSNTNRSNNNNNNNRSNNNNRSNTSNNRTNS 175
Score = 38.5 bits (88), Expect = 0.025
Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 12/100 (12%)
Frame = +1
Query: 58 NRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRN---YYGTRNRGNYSANRGNYCQ 228
N GN +A RSN N T++ NNN N+ N + NR N + NR N
Sbjct: 126 NNGNR-SANASRSNSARNNGGSNTNRSNNNNNNNRSNNNNRSNTSNNRTNSTGNRTNNGG 184
Query: 229 ESR---------LRNDSERSVGSSNGAKSNSLQEMGYSNS 321
++R N+S RS GS+N +++ S + G NS
Sbjct: 185 QNRNNNRTTTNNNNNNSNRSNGSNNSSRNGSGRFGGSLNS 224
Score = 37.7 bits (86), Expect = 0.043
Identities = 25/80 (31%), Positives = 37/80 (46%)
Frame = +1
Query: 82 RGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTRNRGNYSANRGNYCQESRLRNDSERS 261
R + ++HQ D NNN+ N+ N + GN S N GN R +S
Sbjct: 77 RTANQQQSNSRHQQSGDYLNNNRNNNQ-NNSQSRNSNGNRSNNGGN-------RTNSNNG 128
Query: 262 VGSSNGAKSNSLQEMGYSNS 321
S+N ++SNS + G SN+
Sbjct: 129 NRSANASRSNSARNNGGSNT 148
Score = 33.5 bits (75), Expect = 0.81
Identities = 28/99 (28%), Positives = 43/99 (43%)
Frame = +1
Query: 25 QNTNDTHYEMINRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTRNRGNYS 204
Q +N H + G+Y +NR NQ+ ++ N N+ N+ N GN S
Sbjct: 82 QQSNSRHQQS---GDYL-----NNNRNNNQNNSQSRNSNGNRSNNGGNR--TNSNNGNRS 131
Query: 205 ANRGNYCQESRLRNDSERSVGSSNGAKSNSLQEMGYSNS 321
AN R++S R+ G SN +SN+ SN+
Sbjct: 132 ANAS--------RSNSARNNGGSNTNRSNNNNNNNRSNN 162
>sp|O43952|TGP1_TETTH G-quartet DNA binding protein TGP1
Length = 725
Score = 38.5 bits (88), Expect = 0.025
Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 18/99 (18%)
Frame = +1
Query: 82 RGGRSNRGTNQHQYKTDKHNNNQYND-------AFRNYYGTRNRG-----------NYSA 207
RG RS+ N++Q DKH+N+Q N + +N +N+ NY
Sbjct: 490 RGNRSHSQNNRNQRNRDKHHNSQNNQPNKYKNTSVQNNNNNKNQQRSQSQNQRPPRNYDN 549
Query: 208 NRGNYCQESRLRNDSERSVGSSNGAKSNSLQEMGYSNSA 324
+G + +R RN++ R+ + NG + N+ NS+
Sbjct: 550 RQGGENRNNRQRNENNRNNFNGNGHRVNNQNNQRNRNSS 588
>sp|P14196|AAC2_DICDI AAC-rich mRNA clone AAC11 protein
Length = 448
Score = 38.1 bits (87), Expect = 0.033
Identities = 25/116 (21%), Positives = 44/116 (37%)
Frame = +1
Query: 28 NTNDTHYEMINRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTRNRGNYSA 207
N N+ N N +N TN + T+ + NN N+ N T N N +
Sbjct: 288 NNNNNSNNNNNSSNNNNNNNNSTNNNTNNNNNNTNNNTNNNNNNINNNNNNTNNNNNNAN 347
Query: 208 NRGNYCQESRLRNDSERSVGSSNGAKSNSLQEMGYSNSATAQKDRPKLRLLPRSID 375
N+ +++ + ++N +N+ SN+ TA P L S++
Sbjct: 348 NQNTNNNNMGNNSNNNNNPNNNNHQNNNNNNTSNNSNTTTATTTAPGGNNLTNSLN 403
Score = 32.0 bits (71), Expect = 2.4
Identities = 21/104 (20%), Positives = 38/104 (36%), Gaps = 3/104 (2%)
Frame = +1
Query: 28 NTNDTHYEMINRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTR---NRGN 198
N N + N N + S+ N + T+ + NN N+ N N N
Sbjct: 277 NNNSNINNINNNNNNNSNNNNNSSNNNNNNNNSTNNNTNNNNNNTNNNTNNNNNNINNNN 336
Query: 199 YSANRGNYCQESRLRNDSERSVGSSNGAKSNSLQEMGYSNSATA 330
+ N N ++ N++ S+N N+ +N+ T+
Sbjct: 337 NNTNNNNNNANNQNTNNNNMGNNSNNNNNPNNNNHQNNNNNNTS 380
Score = 31.6 bits (70), Expect = 3.1
Identities = 19/99 (19%), Positives = 38/99 (38%)
Frame = +1
Query: 28 NTNDTHYEMINRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTRNRGNYSA 207
N+N+ + N N +N N + + +NNN N N N N +
Sbjct: 268 NSNNNNNNNNNNSNINNINNNNNNNSNNNNNSSNNNNNNN--NSTNNNTNNNNNNTNNNT 325
Query: 208 NRGNYCQESRLRNDSERSVGSSNGAKSNSLQEMGYSNSA 324
N N + + N++ + ++N A + + N++
Sbjct: 326 NNNN----NNINNNNNNTNNNNNNANNQNTNNNNMGNNS 360
>sp|P38922|HRB1_YEAST Protein HRB1 (Protein TOM34)
Length = 429
Score = 37.4 bits (85), Expect = 0.056
Identities = 38/140 (27%), Positives = 62/140 (44%), Gaps = 1/140 (0%)
Frame = +1
Query: 37 DTHYEMINRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTRNRGNYSANR- 213
DT+ +RG Y RGGR + Y+ + NN+ N R+ Y R RG R
Sbjct: 28 DTYRGSRDRGEY---RGGR-----ERSDYRERERFNNRDNPRSRDRYDDRRRGRDVTGRY 79
Query: 214 GNYCQESRLRNDSERSVGSSNGAKSNSLQEMGYSNSATAQKDRPKLRLLPRSIDAPLNEQ 393
GN R+D RS S + + +S + G+ +S P LL R +D+ E+
Sbjct: 80 GN------RRDDYPRSFRSRHNTRDDS-RRGGFGSSGARGDYGP---LLARELDSTYEEK 129
Query: 394 IHSERTAAIFGKGKpreASP 453
++ + +IF +++P
Sbjct: 130 VNRNYSNSIFVGNLTYDSTP 149
>sp|Q69154|IE63_MCMVS Transcriptional regulator IE63 homolog (Protein UL69)
Length = 841
Score = 37.4 bits (85), Expect = 0.056
Identities = 38/155 (24%), Positives = 62/155 (40%), Gaps = 2/155 (1%)
Frame = +1
Query: 58 NRGNYFAARGGRSNRGTNQHQYKTDKHNNNQYNDAFRNYYGTRNRGNYSANRGNYCQESR 237
+RG RG S+ +N H++ T + +D+ + G+R R SA G +
Sbjct: 497 SRGGGGDRRGDSSSTSSNHHRHHTRRARTRSTHDSSSS--GSRRRS--SATDGRRSRRGS 552
Query: 238 LRNDSERSVGSSNGAKS-NSLQEMGYSNSATAQKDRPKLRLLPRSIDAPLNEQIHSERTA 414
R +++R + +KS +++ A+ D R +S P S +TA
Sbjct: 553 RRGEAQRESNGHHSSKSPSTVSSTTVHGQNGARGDSAPSRKSQQSQQQPETTSKESSKTA 612
Query: 415 AIFGKGKpreASPV-REKRVSNLSGDSIENRSRPS 516
A+ P SP RE+R S S PS
Sbjct: 613 AMPPPPSPCSPSPASRERRPSKSPSSSPRPHDPPS 647
>sp|O74786|SEC9_SCHPO Protein transport protein sec9
Length = 419
Score = 37.0 bits (84), Expect = 0.074
Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 8/92 (8%)
Frame = +1
Query: 103 GTNQHQYKTDKHNNNQYNDAFRNYYGTRNRGNY--SANRGNYCQESRL-RNDSERSVGSS 273
GT + Y ++ +N+N N++ Y + N GNY S N G+Y + N S + G+
Sbjct: 37 GTTANSYSSNSYNDN--NNSNSTYGSSNNYGNYGSSNNYGSYGASNTYGSNGSSNNYGNY 94
Query: 274 NGAKSNSLQEMGYS-----NSATAQKDRPKLR 354
SN + GYS N A+KD P ++
Sbjct: 95 GATNSNG--DAGYSITPIRNDPYARKDMPPMK 124
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,153,606
Number of Sequences: 369166
Number of extensions: 1727914
Number of successful extensions: 4420
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3887
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4246
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8886314050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)