Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_C20
(762 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q26648|TKB1_STRPU Tektin-B1 169 8e-42
sp|Q9UIF3|TEKT2_HUMAN Tektin-2 (Testicular tektin) (Tektin-... 139 6e-33
sp|Q6AYM2|TEKT2_RAT Tektin-2 (Testicular tektin) (Tektin-t) 137 3e-32
sp|Q922G7|TEKT2_MOUSE Tektin-2 (Testicular tektin) (Tektin-t) 135 9e-32
sp|Q9BXF9|TEKT3_HUMAN Tektin-3 76 9e-14
sp|Q6X6Z7|TEKT3_MOUSE Tektin-3 72 1e-12
sp|Q99JD2|TEKT1_RAT Tektin-1 68 3e-11
sp|Q969V4|TEKT1_HUMAN Tektin-1 67 4e-11
sp|Q9DAJ2|TEKT1_MOUSE Tektin-1 67 7e-11
sp|Q99323|MYSN_DROME Myosin heavy chain, non-muscle (Zipper... 42 0.002
>sp|Q26648|TKB1_STRPU Tektin-B1
Length = 400
Score = 169 bits (428), Expect = 8e-42
Identities = 97/225 (43%), Positives = 133/225 (59%)
Frame = +2
Query: 44 EPIYTKKPKMSTDPQEWEDFCRYRINRAKTEMVKGQRTREDLHYTAHKVDDMLDHQSQRT 223
+P T+ PK ST PQ WEDF RY +RA EM QR RE +H T + D+ L+ Q Q T
Sbjct: 175 QPNSTRTPKGSTTPQTWEDFSRYNKDRADAEMRSSQRLREAIHSTVAQTDNDLEAQRQAT 234
Query: 224 EYALRKRIHELEQAVSELEYQXXXXXXXXXXXXDDIKALEEAARAKIPSAKLTQTRLENR 403
E+ALRKRIHE+++A E E+Q +I+ LE+A + K KL TRLENR
Sbjct: 235 EFALRKRIHEMKRAKDEDEWQKKNTEEEIAKQERNIRELEQAIKDKENPLKLAMTRLENR 294
Query: 404 LERPRMEQCRDAAQEGLVDEVSQLADSKETLEERLANARNALDGVDKKLAEINDNLNGKK 583
RP +E CRD AQ GLV+EV ++ DS + LE++L +A NA D +K+L IN +L K
Sbjct: 295 TYRPNVELCRDNAQYGLVNEVHEIQDSIKALEKKLQDAHNARDACEKQLYRINKDLELKN 354
Query: 584 HALLLDKMSLDYRVRLKTVPMTRTPCNMIPYGIMREKSVVVR*IL 718
++L LD + R +L T P+T+T N+ + RE R +L
Sbjct: 355 NSLDLDNKCMQVREKLTTGPVTQTMNNLSTFKTDRELYTAQRSLL 399
>sp|Q9UIF3|TEKT2_HUMAN Tektin-2 (Testicular tektin) (Tektin-t) (Testicular tektin B1-like
protein) (Tektin-B1) (TEKTB1)
Length = 430
Score = 139 bits (351), Expect = 6e-33
Identities = 84/207 (40%), Positives = 121/207 (58%)
Frame = +2
Query: 32 SYYVEPIYTKKPKMSTDPQEWEDFCRYRINRAKTEMVKGQRTREDLHYTAHKVDDMLDHQ 211
S V+P T+ P ST Q+W+DF R+ +RA+ EM RE T + ++ L+ Q
Sbjct: 200 SLKVDP--TRVPDGSTTLQQWDDFSRFNKDRAEAEMKAATELREATALTIAETNNELEAQ 257
Query: 212 SQRTEYALRKRIHELEQAVSELEYQXXXXXXXXXXXXDDIKALEEAARAKIPSAKLTQTR 391
TE+A RKR+ E+E+ SEL++Q +DI+ LEE R K+ S KL+ TR
Sbjct: 258 RVATEFAFRKRLREMEKVYSELKWQEKNTLEEIAELQEDIRHLEEDLRTKLLSLKLSHTR 317
Query: 392 LENRLERPRMEQCRDAAQEGLVDEVSQLADSKETLEERLANARNALDGVDKKLAEINDNL 571
LE R RP +E CRD AQ GL DEV QL + L+++LA A++ALD + K LA + ++
Sbjct: 318 LEARTYRPNVELCRDQAQYGLTDEVHQLEATIAALKQKLAQAQDALDALCKHLARLQADI 377
Query: 572 NGKKHALLLDKMSLDYRVRLKTVPMTR 652
K +++LLD +D R +L TVP R
Sbjct: 378 ACKANSMLLDTKCMDTRRKL-TVPAER 403
>sp|Q6AYM2|TEKT2_RAT Tektin-2 (Testicular tektin) (Tektin-t)
Length = 430
Score = 137 bits (345), Expect = 3e-32
Identities = 79/196 (40%), Positives = 112/196 (57%)
Frame = +2
Query: 56 TKKPKMSTDPQEWEDFCRYRINRAKTEMVKGQRTREDLHYTAHKVDDMLDHQSQRTEYAL 235
T+ PK ST QEW+DF R+ NRA TEM RE + + ++ L+ Q TE+
Sbjct: 206 TRVPKDSTTLQEWDDFTRFNKNRADTEMKASIELRETIALAIAQTNNELEAQRVATEFTF 265
Query: 236 RKRIHELEQAVSELEYQXXXXXXXXXXXXDDIKALEEAARAKIPSAKLTQTRLENRLERP 415
RKR+ E+E SEL++Q DI+ LEE R K+ + KL TRLE+R RP
Sbjct: 266 RKRLREMESLYSELKWQEKNTLEEIAELQADIRRLEEDLRRKMMNLKLAHTRLESRTYRP 325
Query: 416 RMEQCRDAAQEGLVDEVSQLADSKETLEERLANARNALDGVDKKLAEINDNLNGKKHALL 595
+E CRD Q GL+DEV QL + ++++LA ++ALD + K LA I ++ K + +L
Sbjct: 326 NVELCRDQTQYGLIDEVHQLEATISIMKQKLAQTQDALDALFKHLARIQADIACKTNTML 385
Query: 596 LDKMSLDYRVRLKTVP 643
LD +D R +L TVP
Sbjct: 386 LDTKCMDIRRKL-TVP 400
>sp|Q922G7|TEKT2_MOUSE Tektin-2 (Testicular tektin) (Tektin-t)
Length = 430
Score = 135 bits (341), Expect = 9e-32
Identities = 79/196 (40%), Positives = 112/196 (57%)
Frame = +2
Query: 56 TKKPKMSTDPQEWEDFCRYRINRAKTEMVKGQRTREDLHYTAHKVDDMLDHQSQRTEYAL 235
T+ PK ST Q+W++F R+ NRA+ EM RE + + ++ LD Q TE+
Sbjct: 206 TRIPKDSTTLQQWDEFTRFNKNRAEAEMKASIELREAIALAIAQTNNELDAQRVATEFTF 265
Query: 236 RKRIHELEQAVSELEYQXXXXXXXXXXXXDDIKALEEAARAKIPSAKLTQTRLENRLERP 415
RKR+ E+E SEL++Q DI+ LEE R K+ + KL TRLE+R R
Sbjct: 266 RKRLREMESFYSELKWQEKNTLEEIAELQGDIRRLEEDLRRKMMNLKLAHTRLESRTYRS 325
Query: 416 RMEQCRDAAQEGLVDEVSQLADSKETLEERLANARNALDGVDKKLAEINDNLNGKKHALL 595
+E CRD Q GL+DEV QL + T++++LA +NALD + K LA I ++ K + LL
Sbjct: 326 NVELCRDQTQYGLIDEVHQLEATINTMKQKLAQTQNALDALFKHLARIQADIACKTNTLL 385
Query: 596 LDKMSLDYRVRLKTVP 643
LD +D R +L TVP
Sbjct: 386 LDTKCMDTRRKL-TVP 400
>sp|Q9BXF9|TEKT3_HUMAN Tektin-3
Length = 490
Score = 76.3 bits (186), Expect = 9e-14
Identities = 46/174 (26%), Positives = 87/174 (50%)
Frame = +2
Query: 83 PQEWEDFCRYRINRAKTEMVKGQRTREDLHYTAHKVDDMLDHQSQRTEYALRKRIHELEQ 262
P+ W F I R+++E + R+D+ + + +Q + + RI E
Sbjct: 297 PESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETAD 356
Query: 263 AVSELEYQXXXXXXXXXXXXDDIKALEEAARAKIPSAKLTQTRLENRLERPRMEQCRDAA 442
A ++++ I+++++A + K K+ QTRL+ R RP +E CRD A
Sbjct: 357 AKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMA 416
Query: 443 QEGLVDEVSQLADSKETLEERLANARNALDGVDKKLAEINDNLNGKKHALLLDK 604
Q LV+EV ++ D+ +TL++RL +A + L + A + +L K ++L +D+
Sbjct: 417 QLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQ 470
>sp|Q6X6Z7|TEKT3_MOUSE Tektin-3
Length = 490
Score = 72.4 bits (176), Expect = 1e-12
Identities = 44/174 (25%), Positives = 84/174 (48%)
Frame = +2
Query: 83 PQEWEDFCRYRINRAKTEMVKGQRTREDLHYTAHKVDDMLDHQSQRTEYALRKRIHELEQ 262
P+ W F + R+++E + RE+ + + +Q + A RI E
Sbjct: 297 PETWAKFTDDNVLRSQSERAASAKLREETENLLIVTANEMWNQFNKVNLAFTNRIAETVD 356
Query: 263 AVSELEYQXXXXXXXXXXXXDDIKALEEAARAKIPSAKLTQTRLENRLERPRMEQCRDAA 442
A +++ I+++++A + K K+ QTRL+ R RP +E CRD A
Sbjct: 357 AKNKIHTHLTKTLQEIFQIEMTIESIKKAIKEKSAFLKVAQTRLDERTRRPNVELCRDMA 416
Query: 443 QEGLVDEVSQLADSKETLEERLANARNALDGVDKKLAEINDNLNGKKHALLLDK 604
Q LV+EV ++ ++ +TL++RL ++ + L + A + +L K + L +D+
Sbjct: 417 QLRLVNEVYEVDETIQTLQQRLRDSEDTLQSLAHTKATLEHDLAVKANTLYIDQ 470
>sp|Q99JD2|TEKT1_RAT Tektin-1
Length = 418
Score = 67.8 bits (164), Expect = 3e-11
Identities = 46/190 (24%), Positives = 86/190 (45%)
Frame = +2
Query: 38 YVEPIYTKKPKMSTDPQEWEDFCRYRINRAKTEMVKGQRTREDLHYTAHKVDDMLDHQSQ 217
Y E + +P S ++W DF + +A ++ + + + + L Q +
Sbjct: 200 YSENVVRIEPN-SVSLEDWLDFSNTNMQKADKQLNNSMALKTLVDQILSQTANDLRRQCE 258
Query: 218 RTEYALRKRIHELEQAVSELEYQXXXXXXXXXXXXDDIKALEEAARAKIPSAKLTQTRLE 397
+ A + E + A ++L +I+ LE A + AK+ TRLE
Sbjct: 259 VVDTAFVNGLKETKDARNKLADHLAKVMDEIASQEKNIEVLENAITQQEGPAKVAHTRLE 318
Query: 398 NRLERPRMEQCRDAAQEGLVDEVSQLADSKETLEERLANARNALDGVDKKLAEINDNLNG 577
NR RP +E CRD AQ L+ EV ++ + LEE LA A+ L + ++ + + +
Sbjct: 319 NRTYRPNVELCRDVAQYRLIREVQEIKHNVARLEETLAQAQIQLKALFRRQLALQEEIQV 378
Query: 578 KKHALLLDKM 607
K++ + +D++
Sbjct: 379 KENTIYIDQV 388
>sp|Q969V4|TEKT1_HUMAN Tektin-1
Length = 418
Score = 67.4 bits (163), Expect = 4e-11
Identities = 54/202 (26%), Positives = 95/202 (47%), Gaps = 11/202 (5%)
Frame = +2
Query: 74 STDPQEWEDFCRYRINRAKTE-----MVKG------QRTREDLHYTAHKVDDMLDHQSQR 220
S ++W DF + +A + M+K +T DL VD + +
Sbjct: 211 SVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKD 270
Query: 221 TEYALRKRIHELEQAVSELEYQXXXXXXXXXXXXDDIKALEEAARAKIPSAKLTQTRLEN 400
T+ A K L + + E+ Q +I ALE+A + AK+ TRLE
Sbjct: 271 TKDARDKLADHLAKVMEEIASQEK-----------NITALEKAILDQEGPAKVAHTRLET 319
Query: 401 RLERPRMEQCRDAAQEGLVDEVSQLADSKETLEERLANARNALDGVDKKLAEINDNLNGK 580
R RP +E CRD AQ L+ EV ++ + L+E LA A+ L G+ ++ + + + K
Sbjct: 320 RTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVK 379
Query: 581 KHALLLDKMSLDYRVRLKTVPM 646
++ + +D++ L ++R K++P+
Sbjct: 380 ENTIYIDEV-LCMQMR-KSIPL 399
>sp|Q9DAJ2|TEKT1_MOUSE Tektin-1
Length = 418
Score = 66.6 bits (161), Expect = 7e-11
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 11/189 (5%)
Frame = +2
Query: 74 STDPQEWEDFCRYRINRAKTEMVKG-----------QRTREDLHYTAHKVDDMLDHQSQR 220
S ++W DF + +A ++ +T DL VD+ + +
Sbjct: 211 SVSLEDWLDFSNANVEKADKQLNNSTALKTLVDQILSQTANDLRRQCEVVDEAFINGLKE 270
Query: 221 TEYALRKRIHELEQAVSELEYQXXXXXXXXXXXXDDIKALEEAARAKIPSAKLTQTRLEN 400
T+ A K L + + E+ Q +I ALE A + AK+ TRLE
Sbjct: 271 TKDARNKLADHLAKVMEEIASQEK-----------NIMALENAITQQEGPAKVAHTRLET 319
Query: 401 RLERPRMEQCRDAAQEGLVDEVSQLADSKETLEERLANARNALDGVDKKLAEINDNLNGK 580
R RP +E CRD AQ L+ E+ ++ + L+E LA A+ L + ++ + + + K
Sbjct: 320 RTHRPNVELCRDIAQYRLIKEIQEINHNVARLKETLAQAQTQLKALYRRQLALQEEIQVK 379
Query: 581 KHALLLDKM 607
++ + +D++
Sbjct: 380 ENTIYIDQV 388
>sp|Q99323|MYSN_DROME Myosin heavy chain, non-muscle (Zipper protein) (Myosin II)
(Non-muscle MHC)
Length = 2057
Score = 42.0 bits (97), Expect = 0.002
Identities = 38/162 (23%), Positives = 72/162 (44%), Gaps = 10/162 (6%)
Frame = +2
Query: 116 INRAKTEMVKGQRTRE----DLHYTAHKVDDMLDHQSQRTEYA------LRKRIHELEQA 265
+ +AKT + K + T E DL V+ +R + A L+ ++ E+E+A
Sbjct: 1299 LRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERA 1358
Query: 266 VSELEYQXXXXXXXXXXXXDDIKALEEAARAKIPSAKLTQTRLENRLERPRMEQCRDAAQ 445
SEL+ + + ++ E A A + SA +++L E ++ + +
Sbjct: 1359 RSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQL---TEAQQLLEEETRQK 1415
Query: 446 EGLVDEVSQLADSKETLEERLANARNALDGVDKKLAEINDNL 571
GL ++ Q+ KE L+E+L A ++KLAE+ +
Sbjct: 1416 LGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQM 1457
Score = 35.8 bits (81), Expect = 0.13
Identities = 39/169 (23%), Positives = 70/169 (41%), Gaps = 2/169 (1%)
Frame = +2
Query: 59 KKPKMSTDPQEWEDFCRYRINRAKTEMVKGQRTREDLHYTAHKVDDMLDHQSQRTEYALR 238
K +++T QE + + AK +R +D+ +V +++ Q+ R + + +
Sbjct: 1449 KLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELIA-QNDRLDKSKK 1507
Query: 239 KRIHELEQAVSELEYQ--XXXXXXXXXXXXDDIKALEEAARAKIPSAKLTQTRLENRLER 412
K ELE A ELE Q D I A E+A +I + T R E
Sbjct: 1508 KIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKET 1567
Query: 413 PRMEQCRDAAQEGLVDEVSQLADSKETLEERLANARNALDGVDKKLAEI 559
+ R+ + D++ L + ++TL+ L + N DK + E+
Sbjct: 1568 KVLSVSREL--DEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHEL 1614
Score = 33.9 bits (76), Expect = 0.49
Identities = 39/136 (28%), Positives = 57/136 (41%), Gaps = 6/136 (4%)
Frame = +2
Query: 161 EDLHYTAHKVDDMLDHQSQRTEYALRKRIHELEQAVSELEYQXXXXXXXXXXXXDDIKAL 340
EDL + + LD + T+ K +HELE+A LE Q DD++
Sbjct: 1584 EDLENKRKTLQNELDDLAN-TQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLT 1642
Query: 341 EEAARAKIPSAKLTQTRLENRLERPRMEQCRD--AAQEGLVDE----VSQLADSKETLEE 502
E+A + RLE ++ R + RD A +EG ++ V QL D + L+E
Sbjct: 1643 EDA-----------KLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDE 1691
Query: 503 RLANARNALDGVDKKL 550
R A KKL
Sbjct: 1692 E-RKQRTAAVASKKKL 1706
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,670,383
Number of Sequences: 369166
Number of extensions: 1118720
Number of successful extensions: 3942
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3786
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3926
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7018522000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)