Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_C12
(222 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BUN8|DERL1_HUMAN Derlin-1 (Degradation in endoplasmic ... 63 2e-10
sp|Q5R9W3|DERL1_PONPY Derlin-1 (Degradation in endoplasmic ... 63 2e-10
sp|Q71SS4|DERL1_BOVIN Derlin-1 (Degradation in endoplasmic ... 62 4e-10
sp|Q99J56|DERL1_MOUSE Derlin-1 (Degradation in endoplasmic ... 62 5e-10
sp|Q93561|DERL1_CAEEL Derlin-1 (DER1-like protein 1) (cDerl... 50 1e-06
sp|Q12743|DFM1_YEAST DER1-like family member protein 1 34 0.090
sp|Q9VQ57|DERL1_DROME Derlin-1 (DER1-like protein 1) 33 0.15
sp|P38307|DER1_YEAST Degradation in the endoplasmic reticul... 32 0.45
sp|Q5JEX8|HAM1_PYRKO HAM1 protein homolog 29 2.9
sp|O67292|CDSA_AQUAE Phosphatidate cytidylyltransferase (CD... 29 3.8
>sp|Q9BUN8|DERL1_HUMAN Derlin-1 (Degradation in endoplasmic reticulum protein 1)
(Der1-like protein 1) (DERtrin-1)
Length = 251
Score = 62.8 bits (151), Expect = 2e-10
Identities = 24/50 (48%), Positives = 37/50 (74%)
Frame = +3
Query: 39 NDIGDWYRSIPIVSKYWFSGSIIFPLIGKLGLVDPYKMVLMWAPFIEKFQ 188
+DIGDW+RSIP +++YWF+ ++ PL+GKLGL+ P + L F+ +FQ
Sbjct: 2 SDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQ 51
>sp|Q5R9W3|DERL1_PONPY Derlin-1 (Degradation in endoplasmic reticulum protein 1)
(Der1-like protein 1)
Length = 251
Score = 62.8 bits (151), Expect = 2e-10
Identities = 24/50 (48%), Positives = 37/50 (74%)
Frame = +3
Query: 39 NDIGDWYRSIPIVSKYWFSGSIIFPLIGKLGLVDPYKMVLMWAPFIEKFQ 188
+DIGDW+RSIP +++YWF+ ++ PL+GKLGL+ P + L F+ +FQ
Sbjct: 2 SDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQ 51
>sp|Q71SS4|DERL1_BOVIN Derlin-1 (Degradation in endoplasmic reticulum protein 1)
(Der1-like protein 1)
Length = 251
Score = 62.0 bits (149), Expect = 4e-10
Identities = 24/50 (48%), Positives = 36/50 (72%)
Frame = +3
Query: 39 NDIGDWYRSIPIVSKYWFSGSIIFPLIGKLGLVDPYKMVLMWAPFIEKFQ 188
+DIGDW+RSIP +++YWF+ ++ PL+GKLGL+ P L F+ +FQ
Sbjct: 2 SDIGDWFRSIPTITRYWFAATVAVPLVGKLGLISPAYFFLWPEAFLYRFQ 51
>sp|Q99J56|DERL1_MOUSE Derlin-1 (Degradation in endoplasmic reticulum protein 1)
(Der1-like protein 1)
Length = 251
Score = 61.6 bits (148), Expect = 5e-10
Identities = 24/50 (48%), Positives = 36/50 (72%)
Frame = +3
Query: 39 NDIGDWYRSIPIVSKYWFSGSIIFPLIGKLGLVDPYKMVLMWAPFIEKFQ 188
+DIGDW+RSIP +++YWF+ ++ PLIGKLG++ P L F+ +FQ
Sbjct: 2 SDIGDWFRSIPAITRYWFAATVAVPLIGKLGIISPAYFFLWPEAFLYRFQ 51
>sp|Q93561|DERL1_CAEEL Derlin-1 (DER1-like protein 1) (cDerlin-1)
Length = 245
Score = 50.4 bits (119), Expect = 1e-06
Identities = 21/50 (42%), Positives = 31/50 (62%)
Frame = +3
Query: 42 DIGDWYRSIPIVSKYWFSGSIIFPLIGKLGLVDPYKMVLMWAPFIEKFQF 191
D+ ++ IPIV++YWF S I PL+G+ G ++ M L W + KFQF
Sbjct: 2 DLENFLLGIPIVTRYWFLASTIIPLLGRFGFINVQWMFLQWDLVVNKFQF 51
>sp|Q12743|DFM1_YEAST DER1-like family member protein 1
Length = 341
Score = 34.3 bits (77), Expect = 0.090
Identities = 14/57 (24%), Positives = 36/57 (63%)
Frame = +3
Query: 51 DWYRSIPIVSKYWFSGSIIFPLIGKLGLVDPYKMVLMWAPFIEKFQFGDQLLHYCII 221
+++ +IP +++ F+ +I+ ++G+L L++P+ + +W +K Q +LL C++
Sbjct: 25 EFWLNIPPITRTLFTLAIVMTIVGRLNLINPWYFIYVWNLTFKKVQIW-RLLTSCVM 80
>sp|Q9VQ57|DERL1_DROME Derlin-1 (DER1-like protein 1)
Length = 245
Score = 33.5 bits (75), Expect = 0.15
Identities = 12/49 (24%), Positives = 27/49 (55%)
Frame = +3
Query: 42 DIGDWYRSIPIVSKYWFSGSIIFPLIGKLGLVDPYKMVLMWAPFIEKFQ 188
D G WYRS+P ++YW + +++ ++ + ++ + + L + K Q
Sbjct: 2 DAGVWYRSLPRFTRYWLTATVVLSMLCRFDVIPLHWLHLDRSAVFSKLQ 50
>sp|P38307|DER1_YEAST Degradation in the endoplasmic reticulum protein 1
Length = 211
Score = 32.0 bits (71), Expect = 0.45
Identities = 17/52 (32%), Positives = 29/52 (55%)
Frame = +3
Query: 39 NDIGDWYRSIPIVSKYWFSGSIIFPLIGKLGLVDPYKMVLMWAPFIEKFQFG 194
N +GD IP+V++ W G ++ + L +VDP K+V + +K Q+G
Sbjct: 7 NLLGD----IPLVTRLWTIGCLVLSGLTSLRIVDPGKVVYSYDLVFKKGQYG 54
>sp|Q5JEX8|HAM1_PYRKO HAM1 protein homolog
Length = 184
Score = 29.3 bits (64), Expect = 2.9
Identities = 9/20 (45%), Positives = 17/20 (85%)
Frame = -3
Query: 88 QYFETIGIDLYQSPISFPDI 29
+YFE +G+++YQ +S+P+I
Sbjct: 18 KYFEPLGVEVYQLKVSYPEI 37
>sp|O67292|CDSA_AQUAE Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase)
(CDP-diglyceride pyrophosphorylase) (CDP-diacylglycerol
synthase) (CDS) (CTP:phosphatidate cytidylyltransferase)
(CDP-DAG synthase) (CDP-DG synthetase)
Length = 259
Score = 28.9 bits (63), Expect = 3.8
Identities = 13/32 (40%), Positives = 20/32 (62%)
Frame = +3
Query: 54 WYRSIPIVSKYWFSGSIIFPLIGKLGLVDPYK 149
+Y S ++ Y+F+ ++FPLIG L L YK
Sbjct: 65 FYFSPLVLLTYYFADPLVFPLIGLLSLYFAYK 96
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,366,078
Number of Sequences: 369166
Number of extensions: 448195
Number of successful extensions: 1119
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1109
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1119
length of database: 68,354,980
effective HSP length: 45
effective length of database: 60,041,905
effective search space used: 1681173340
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)