Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_A08
(587 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine ... 238 8e-63
sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine ... 237 2e-62
sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine ... 233 2e-61
sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine ca... 230 2e-60
sp|Q27257|DIF1_CAEEL Protein dif-1 217 2e-56
sp|Q9VQG4|COLT_DROME Congested-like trachea protein 198 7e-51
sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine ... 122 9e-28
sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1... 114 1e-25
sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1... 113 4e-25
sp|Q12289|CRC1_YEAST Mitochondrial carnitine carrier 105 6e-23
>sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 238 bits (607), Expect = 8e-63
Identities = 116/176 (65%), Positives = 136/176 (77%)
Frame = +1
Query: 1 GVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRD 180
GVFTT IMTPGERIKCLLQ+Q +S E KY G D +KLY+E GIR IYKGT TL+RD
Sbjct: 121 GVFTTGIMTPGERIKCLLQIQASSGES-KYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRD 179
Query: 181 IPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQT 360
+PA+G YFM+YEWLK I TPEG S LS R L AGGIAG+ NW V IPPD LKSR QT
Sbjct: 180 VPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQT 239
Query: 361 APEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLN 528
AP GKYP+G R V RE++ +EG+ LY+G + V+IRAFPANAACFLG+EV++K LN
Sbjct: 240 APPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFLN 295
Score = 66.6 bits (161), Expect = 4e-11
Identities = 40/95 (42%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 262 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEG 426
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREG 67
Query: 427 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 531
I GLYRG++ +I P A CF G+ + KL K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK 102
Score = 61.2 bits (147), Expect = 2e-09
Identities = 50/174 (28%), Positives = 78/174 (44%), Gaps = 5/174 (2%)
Frame = +1
Query: 1 GVFTTAIMTPGERIKCLLQVQGASK--EPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLL 174
GV + P + +K LQ Q S +PP Y G D RK GI +Y+G AA ++
Sbjct: 21 GVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYRGMAAPII 80
Query: 175 RDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRL 354
P F + K++ D LS + AG ++G+ + P + +K L
Sbjct: 81 GVTPMFAVCFFGFGLGKKLQQKHPEDV--LSYPQLFAAGMLSGVFTTGIMTPGERIKCLL 138
Query: 355 Q---TAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYE 507
Q ++ E KY G +++ GI G+Y+G L+R PA+ F+ YE
Sbjct: 139 QIQASSGESKYT-GTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYE 191
>sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 237 bits (604), Expect = 2e-62
Identities = 114/176 (64%), Positives = 136/176 (77%)
Frame = +1
Query: 1 GVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRD 180
G+FTT IMTPGERIKCLLQ+Q +S E KY G D +KLY+E GIR IYKGT TL+RD
Sbjct: 121 GIFTTGIMTPGERIKCLLQIQASSGET-KYTGTLDCAKKLYQEFGIRGIYKGTVVTLMRD 179
Query: 181 IPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQT 360
+PA+G YFM+YEW+K I TPEG S LS R L AGGIAG+ NW V IPPD LKSR QT
Sbjct: 180 VPASGMYFMTYEWVKNIFTPEGKRVSELSVPRVLVAGGIAGIFNWAVAIPPDVLKSRFQT 239
Query: 361 APEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLN 528
AP GKYP+G R V RE++ +EG+ LY+G + V+IRAFPANAACFLG+EV++K LN
Sbjct: 240 APPGKYPNGFRDVLRELIPDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFLN 295
Score = 65.5 bits (158), Expect = 1e-10
Identities = 40/95 (42%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 262 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEG 426
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREG 67
Query: 427 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 531
I GLYRG++ +I P A CF G+ + KL K
Sbjct: 68 IRGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK 102
Score = 63.2 bits (152), Expect = 5e-10
Identities = 51/174 (29%), Positives = 79/174 (45%), Gaps = 5/174 (2%)
Frame = +1
Query: 1 GVFTTAIMTPGERIKCLLQVQGASK--EPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLL 174
GV + P + +K LQ Q S +PP Y G D RK GIR +Y+G AA ++
Sbjct: 21 GVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGIRGLYRGMAAPII 80
Query: 175 RDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRL 354
P F + K++ D LS + AG ++G+ + P + +K L
Sbjct: 81 GVTPMFAVCFFGFGLGKKLQQKHPEDV--LSYPQLFAAGMLSGIFTTGIMTPGERIKCLL 138
Query: 355 Q---TAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYE 507
Q ++ E KY G +++ GI G+Y+G L+R PA+ F+ YE
Sbjct: 139 QIQASSGETKYT-GTLDCAKKLYQEFGIRGIYKGTVVTLMRDVPASGMYFMTYE 191
>sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC) (mCAC)
Length = 301
Score = 233 bits (595), Expect = 2e-61
Identities = 112/176 (63%), Positives = 133/176 (75%)
Frame = +1
Query: 1 GVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRD 180
GVFTT IMTPGERIKCLLQ+Q +S E KY G D +KLY+E GIR YKGT TL+RD
Sbjct: 121 GVFTTGIMTPGERIKCLLQIQASSGEN-KYSGTLDCAKKLYQEFGIRGFYKGTVLTLMRD 179
Query: 181 IPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQT 360
+PA+G YFM+YEWLK + TPEG S LS R L AGG AG+ NW V IPPD LKSR QT
Sbjct: 180 VPASGMYFMTYEWLKNLFTPEGKSVSDLSVPRILVAGGFAGIFNWAVAIPPDVLKSRFQT 239
Query: 361 APEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLN 528
AP GKYP+G R V RE++ EG+ LY+G + V+IRAFPANAACFLG+E+++K LN
Sbjct: 240 APPGKYPNGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFEIAMKFLN 295
Score = 69.7 bits (169), Expect = 5e-12
Identities = 41/95 (43%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 262 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYP--HGLRSVFREMMANEG 426
+SP + L AGG GMC V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREG 67
Query: 427 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 531
I GLYRG++ +I P A CF G+ + KL K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK 102
Score = 61.6 bits (148), Expect = 1e-09
Identities = 47/165 (28%), Positives = 75/165 (45%), Gaps = 5/165 (3%)
Frame = +1
Query: 28 PGERIKCLLQVQ--GASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTY 201
P + +K LQ Q S +PP Y G D RK GI +Y+G AA ++ P
Sbjct: 30 PLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREGITGLYRGMAAPIIGVTPMFAVC 89
Query: 202 FMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQ---TAPEG 372
F + K++ + + LS + AG ++G+ + P + +K LQ ++ E
Sbjct: 90 FFGFGLGKKL--QQKSPEDELSYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQASSGEN 147
Query: 373 KYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYE 507
KY G +++ GI G Y+G L+R PA+ F+ YE
Sbjct: 148 KY-SGTLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASGMYFMTYE 191
>sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 230 bits (586), Expect = 2e-60
Identities = 110/176 (62%), Positives = 132/176 (75%)
Frame = +1
Query: 1 GVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRD 180
GVFTT IMTPGERIKCLLQ+Q AS KY G D +KLY+E GIR YKGTA TL+RD
Sbjct: 121 GVFTTGIMTPGERIKCLLQIQ-ASSGKNKYSGTLDCAKKLYQEFGIRGFYKGTALTLMRD 179
Query: 181 IPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQT 360
+PA+G YFM+YEWLK + TP+G LS R L AGG G+ NW+V IPPD LKSR QT
Sbjct: 180 VPASGMYFMTYEWLKNLFTPQGKSVHDLSVPRVLVAGGFRGIFNWVVAIPPDVLKSRFQT 239
Query: 361 APEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLN 528
AP GKYP+G R V RE++ EG+ LY+G + V+IRAFPANAACFLG+E+ +K+LN
Sbjct: 240 APPGKYPNGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFEIPMKILN 295
Score = 65.5 bits (158), Expect = 1e-10
Identities = 39/95 (41%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +1
Query: 262 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEG 426
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREG 67
Query: 427 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 531
I GLYRG++ +I P A CF G+ + +L K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKRLQQK 102
Score = 60.1 bits (144), Expect = 4e-09
Identities = 48/173 (27%), Positives = 77/173 (44%), Gaps = 4/173 (2%)
Frame = +1
Query: 1 GVFTTAIMTPGERIKCLLQVQGASK--EPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLL 174
GV + P + +K LQ Q S +PP Y G D RK GI +Y+G AA ++
Sbjct: 21 GVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREGITGLYRGMAAPII 80
Query: 175 RDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRL 354
P F + K + + + L+ + AG ++G+ + P + +K L
Sbjct: 81 GVTPMFAVCFFGFGLGKRL--QQKSPEDELTYPQLFTAGMLSGVFTTGIMTPGERIKCLL 138
Query: 355 Q-TAPEGKYPH-GLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYE 507
Q A GK + G +++ GI G Y+G + L+R PA+ F+ YE
Sbjct: 139 QIQASSGKNKYSGTLDCAKKLYQEFGIRGFYKGTALTLMRDVPASGMYFMTYE 191
>sp|Q27257|DIF1_CAEEL Protein dif-1
Length = 312
Score = 217 bits (553), Expect = 2e-56
Identities = 108/174 (62%), Positives = 132/174 (75%), Gaps = 2/174 (1%)
Frame = +1
Query: 1 GVFTTAIMTPGERIKCLLQVQ--GASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLL 174
GVFTT +M PGERIKCLLQVQ G++ Y GP DV++KLYK+GGI SIY+GT ATLL
Sbjct: 115 GVFTTIVMVPGERIKCLLQVQQAGSAGSGVHYDGPLDVVKKLYKQGGISSIYRGTGATLL 174
Query: 175 RDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRL 354
RDIPA+ Y YE+LK+ + EG ++ LSPG TL AGG+AG+ NW VCIP D LKSRL
Sbjct: 175 RDIPASAAYLSVYEYLKKKFSGEGAQRT-LSPGATLMAGGLAGIANWGVCIPADVLKSRL 233
Query: 355 QTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSL 516
QTAPEGKYP G+R V RE++ EG L++G PV++RAFPANAACF G E++L
Sbjct: 234 QTAPEGKYPDGIRGVLREVLREEGPRALFKGFWPVMLRAFPANAACFFGLELTL 287
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Frame = +1
Query: 286 AGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYPH--GLRSVFREMMANEGIVGLYRGV 450
AGG+ G C +V P DT+K R+QT P G+ P G + ++ EG LY+G+
Sbjct: 10 AGGVGGSCTVIVGHPFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFALYKGM 69
Query: 451 SPVLIRAFPANAACFLGYEV 510
+ L+ P A F G V
Sbjct: 70 AAPLVGVSPLFAVFFGGCAV 89
>sp|Q9VQG4|COLT_DROME Congested-like trachea protein
Length = 306
Score = 198 bits (504), Expect = 7e-51
Identities = 94/178 (52%), Positives = 128/178 (71%)
Frame = +1
Query: 1 GVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRD 180
G+F+T IM PGERIK LLQ Q KY G D KLYKEGG+RS++KG+ AT+LRD
Sbjct: 126 GLFSTLIMAPGERIKVLLQTQQGQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRD 185
Query: 181 IPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQT 360
+PA G YF+ YE L+++ + + +S T+FAGG+AGM W++ +P D LKSRLQ+
Sbjct: 186 LPANGLYFLVYEALQDVAKSKS-ETGQISTASTIFAGGVAGMAYWILGMPADVLKSRLQS 244
Query: 361 APEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNKV 534
APEG Y HG+RSVF++++ +G + LYRGV+P+++RAFPANAACF G E++ K N V
Sbjct: 245 APEGTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRAFPANAACFFGIELANKFFNIV 302
Score = 65.1 bits (157), Expect = 1e-10
Identities = 49/166 (29%), Positives = 77/166 (46%), Gaps = 6/166 (3%)
Frame = +1
Query: 28 PGERIKCLLQV--QGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTY 201
P + IK LQ + A E P Y+G D K K G+R +YKG +A L P
Sbjct: 35 PLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGVAPIFAMC 94
Query: 202 FMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQT----APE 369
F Y K + + G+ + L+ + AG +G+ + L+ P + +K LQT E
Sbjct: 95 FAGYALGKRL--QQRGEDAKLTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQTQQGQGGE 152
Query: 370 GKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYE 507
KY +G+ ++ G+ +++G ++R PAN FL YE
Sbjct: 153 RKY-NGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYE 197
Score = 60.1 bits (144), Expect = 4e-09
Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 5/91 (5%)
Frame = +1
Query: 265 SPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEGI 429
+P ++ GG G+CN L P DT+K RLQT P G+ P G + + NEG+
Sbjct: 14 NPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGV 73
Query: 430 VGLYRGVSPVLIRAFPANAACFLGYEVSLKL 522
GLY+G+S L P A CF GY + +L
Sbjct: 74 RGLYKGMSAPLTGVAPIFAMCFAGYALGKRL 104
>sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine carrier-like protein (A BOUT
DE SOUFFLE) (Carnitine/acylcarnitine translocase-like
protein) (CAC-like protein)
Length = 300
Score = 122 bits (305), Expect = 9e-28
Identities = 73/183 (39%), Positives = 97/183 (53%), Gaps = 12/183 (6%)
Frame = +1
Query: 1 GVFTTAIMTPGERIKCLLQVQGASKEPP---------KYKGPGDVIRKLYK-EGGIRSIY 150
G + + P E IKC LQ QGA KY GP DV R + + EGG R ++
Sbjct: 115 GFAVSFLACPTELIKCRLQAQGALAGASTTSSVVAAVKYGGPMDVARHVLRSEGGARGLF 174
Query: 151 KGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIP 330
KG T R++P T F +YE K L G D S L G + AGG+AG W + P
Sbjct: 175 KGLFPTFAREVPGNATMFAAYEAFKRFLAG-GSDTSSLGQGSLIMAGGVAGASFWGIVYP 233
Query: 331 PDTLKSRLQTAPEGKYPH--GLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGY 504
D +KS LQ + K P G FR+++ +EG+ GLY+G P + R+ PANAACFL Y
Sbjct: 234 TDVVKSVLQV-DDYKNPRYTGSMDAFRKILKSEGVKGLYKGFGPAMARSVPANAACFLAY 292
Query: 505 EVS 513
E++
Sbjct: 293 EMT 295
Score = 53.9 bits (128), Expect = 3e-07
Identities = 50/182 (27%), Positives = 73/182 (40%), Gaps = 16/182 (8%)
Frame = +1
Query: 28 PGERIKCLLQVQG--ASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTY 201
P + IK LQ Q A + P+Y G D +++ G + +YKG A L
Sbjct: 24 PFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGTKGLYKGMGAPLATVAAFNAVL 83
Query: 202 FMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQT------- 360
F ++ +L E G +S + AG AG + P + +K RLQ
Sbjct: 84 FTVRGQMEGLLRSEAGVPLTIS--QQFVAGAGAGFAVSFLACPTELIKCRLQAQGALAGA 141
Query: 361 ------APEGKYPHGLRSVFREMMANEGIV-GLYRGVSPVLIRAFPANAACFLGYEVSLK 519
KY G V R ++ +EG GL++G+ P R P NA F YE +
Sbjct: 142 STTSSVVAAVKYG-GPMDVARHVLRSEGGARGLFKGLFPTFAREVPGNATMFAAYEAFKR 200
Query: 520 LL 525
L
Sbjct: 201 FL 202
Score = 50.1 bits (118), Expect = 4e-06
Identities = 24/72 (33%), Positives = 38/72 (52%)
Frame = +1
Query: 19 IMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGT 198
I+ P + +K +LQV P+Y G D RK+ K G++ +YKG + R +PA
Sbjct: 230 IVYPTDVVKSVLQVDDYKN--PRYTGSMDAFRKILKSEGVKGLYKGFGPAMARSVPANAA 287
Query: 199 YFMSYEWLKEIL 234
F++YE + L
Sbjct: 288 CFLAYEMTRSSL 299
>sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1 (Solute carrier family 25
member 15)
Length = 301
Score = 114 bits (286), Expect = 1e-25
Identities = 63/177 (35%), Positives = 91/177 (51%), Gaps = 4/177 (2%)
Frame = +1
Query: 7 FTTAIMTPGERIKCLLQ----VQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLL 174
F ++ P E +KC LQ ++ + K V+++++++ G Y G ++TLL
Sbjct: 119 FAALVLCPTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLL 178
Query: 175 RDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRL 354
R++P +F YE L G K L P + +GG G+C WL P D +KSR+
Sbjct: 179 REVPGYFFFFGGYE-LSRSFFASGRSKDELGPVPLMLSGGFGGICLWLAVYPVDCIKSRI 237
Query: 355 QTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLL 525
Q GL F ++ NEGI LY G+ P +IRAFPAN A FL YE S KL+
Sbjct: 238 QVLSMTGKQTGLVRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLM 294
Score = 71.6 bits (174), Expect = 1e-12
Identities = 50/154 (32%), Positives = 74/154 (48%), Gaps = 9/154 (5%)
Frame = +1
Query: 79 PPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGG--D 252
P Y+G D K Y + G R YKGT+ L+ +I FM Y + ++++ G
Sbjct: 41 PDLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVVGLDQ 100
Query: 253 KSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE----GKY---PHGLRSVFREM 411
++ LS + AG A LV P + +K RLQT E GK + + SV +E+
Sbjct: 101 QAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEI 160
Query: 412 MANEGIVGLYRGVSPVLIRAFPANAACFLGYEVS 513
+G +G Y G+S L+R P F GYE+S
Sbjct: 161 FRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELS 194
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/85 (31%), Positives = 39/85 (45%)
Frame = +1
Query: 280 LFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPV 459
L AG G L P DT+K ++QT P+ GL + + G G Y+G SP
Sbjct: 13 LTAGAAGGTACVLTGQPFDTMKVKMQTFPD--LYRGLTDCCLKTYSQVGFRGFYKGTSPA 70
Query: 460 LIRAFPANAACFLGYEVSLKLLNKV 534
LI N+ F+ Y +++ KV
Sbjct: 71 LIANIAENSVLFMCYGFCQQVVRKV 95
>sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1 (Solute carrier family 25,
member 15)
Length = 301
Score = 113 bits (282), Expect = 4e-25
Identities = 63/177 (35%), Positives = 89/177 (50%), Gaps = 4/177 (2%)
Frame = +1
Query: 7 FTTAIMTPGERIKCLLQ----VQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLL 174
F ++ P E +KC LQ ++ + K VI+ + ++ G Y G ++TLL
Sbjct: 119 FAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLL 178
Query: 175 RDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRL 354
R++P +F YE L G K L P + +GG+ G+C WL P D +KSR+
Sbjct: 179 REVPGYFFFFGGYE-LSRSFFASGRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRI 237
Query: 355 QTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLL 525
Q G F ++ NEGI LY G+ P +IRAFPAN A FL YE S KL+
Sbjct: 238 QVLSMSGKQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLM 294
Score = 73.2 bits (178), Expect = 5e-13
Identities = 48/154 (31%), Positives = 73/154 (47%), Gaps = 9/154 (5%)
Frame = +1
Query: 79 PPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGG--D 252
P Y+G D K Y + G R YKGT+ L+ +I FM Y + ++++ G
Sbjct: 41 PDLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDK 100
Query: 253 KSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE-------GKYPHGLRSVFREM 411
++ LS + AG A LV P + +K RLQT E K + + SV + +
Sbjct: 101 QAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSI 160
Query: 412 MANEGIVGLYRGVSPVLIRAFPANAACFLGYEVS 513
+ +G +G Y G+S L+R P F GYE+S
Sbjct: 161 LRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELS 194
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/85 (31%), Positives = 39/85 (45%)
Frame = +1
Query: 280 LFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPV 459
L AG G L P DT+K ++QT P+ GL + + G G Y+G SP
Sbjct: 13 LTAGAAGGTACVLTGQPFDTMKVKMQTFPD--LYRGLTDCCLKTYSQVGFRGFYKGTSPA 70
Query: 460 LIRAFPANAACFLGYEVSLKLLNKV 534
LI N+ F+ Y +++ KV
Sbjct: 71 LIANIAENSVLFMCYGFCQQVVRKV 95
>sp|Q12289|CRC1_YEAST Mitochondrial carnitine carrier
Length = 327
Score = 105 bits (263), Expect = 6e-23
Identities = 68/181 (37%), Positives = 95/181 (52%), Gaps = 7/181 (3%)
Frame = +1
Query: 10 TTAIMTPGERIKCLLQVQGASKEPPKYKGPG-DVIRKLYKEGGIRSIYKGTAATLLRDIP 186
TT + P ER+K +LQ KG + + KEGGI S++KG+ ATL RD P
Sbjct: 155 TTLVTAPTERVKVVLQTSS--------KGSFIQAAKTIVKEGGIASLFKGSLATLARDGP 206
Query: 187 ATGTYFMSYEWLKEILT-----PEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSR 351
+ YF SYE K L + G ++ AGGIAGM WL P DT+K++
Sbjct: 207 GSALYFASYEISKNYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAVFPIDTIKTK 266
Query: 352 LQTAPEGKYPHGLRSVFREM-MANEGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLN 528
LQ + + + S +E+ + GI G + G+ P L+R+FPANAA FLG E++ L
Sbjct: 267 LQASSTRQ---NMLSATKEIYLQRGGIKGFFPGLGPALLRSFPANAATFLGVEMTHSLFK 323
Query: 529 K 531
K
Sbjct: 324 K 324
Score = 47.4 bits (111), Expect = 3e-05
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 7/91 (7%)
Frame = +1
Query: 274 RTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREM-------MANEGIV 432
++ AGG+ G+C P D +K R Q H + ++ +E + +
Sbjct: 37 KSFVAGGVGGVCAVFTGHPFDLIKVRCQNGQANSTVHAITNIIKEAKTQVKGTLFTNSVK 96
Query: 433 GLYRGVSPVLIRAFPANAACFLGYEVSLKLL 525
G Y+GV P L+ P A F GY+V KL+
Sbjct: 97 GFYKGVIPPLLGVTPIFAVSFWGYDVGKKLV 127
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,533,726
Number of Sequences: 369166
Number of extensions: 1591155
Number of successful extensions: 4814
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4148
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4535
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4406202450
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)