Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_A07
(777 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q90705|EF2_CHICK Elongation factor 2 (EF-2) 390 e-108
sp|P13639|EF2_HUMAN Elongation factor 2 (EF-2) 388 e-107
sp|P58252|EF2_MOUSE Elongation factor 2 (EF-2) 387 e-107
sp|P05086|EF2_MESAU Elongation factor 2 (EF-2) 387 e-107
sp|P05197|EF2_RAT Elongation factor 2 (EF-2) 387 e-107
sp|P09445|EF2_CRIGR Elongation factor 2 (EF-2) 380 e-105
sp|P29691|EF2_CAEEL Elongation factor 2 (EF-2) 376 e-104
sp|P13060|EF2_DROME Elongation factor 2 (EF-2) 371 e-102
sp|Q6BJ25|EF2_DEBHA Elongation factor 2 (EF-2) 328 1e-89
sp|O13430|EF2_CANAL Elongation factor 2 (EF-2) 322 5e-88
>sp|Q90705|EF2_CHICK Elongation factor 2 (EF-2)
Length = 858
Score = 390 bits (1002), Expect = e-108
Identities = 177/246 (71%), Positives = 207/246 (84%)
Frame = +1
Query: 10 LSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYL 189
L+ DID G+++AR E+K+R RYL E Y+WDVTE+RKIWCFGPDG GPN++ D++KGVQYL
Sbjct: 613 LAEDIDKGEVSARQELKQRARYLAEKYEWDVTEARKIWCFGPDGTGPNILTDITKGVQYL 672
Query: 190 NEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTARRCFYAS 369
NEIKDSVVA F WATK+GVLCEENMRGVRF++HDVTLHADAIHRGGGQIIPTARRC YA
Sbjct: 673 NEIKDSVVAGFQWATKEGVLCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYAC 732
Query: 370 VLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNE 549
VLTA P L+EP+Y EIQ PE +GGIY LN++RG +F E QVAGTP +VVKAYLPVNE
Sbjct: 733 VLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNE 792
Query: 550 SFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLD 729
SF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P D S+P V +TRKRKGL E +P LD
Sbjct: 793 SFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDSASRPSQVVAETRKRKGLKEGIPALD 852
Query: 730 KFLDKL 747
FLDKL
Sbjct: 853 NFLDKL 858
>sp|P13639|EF2_HUMAN Elongation factor 2 (EF-2)
Length = 858
Score = 388 bits (996), Expect = e-107
Identities = 176/246 (71%), Positives = 206/246 (83%)
Frame = +1
Query: 10 LSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYL 189
L+ DID G+++AR E+K+R RYL E Y+WDV E+RKIWCFGPDG GPN++ D++KGVQYL
Sbjct: 613 LAEDIDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYL 672
Query: 190 NEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTARRCFYAS 369
NEIKDSVVA F WATK+G LCEENMRGVRF++HDVTLHADAIHRGGGQIIPTARRC YAS
Sbjct: 673 NEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYAS 732
Query: 370 VLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNE 549
VLTA P L+EP+Y EIQ PE +GGIY LN++RG +F E QVAGTP +VVKAYLPVNE
Sbjct: 733 VLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNE 792
Query: 550 SFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLD 729
SF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P D S+P V +TRKRKGL E +P LD
Sbjct: 793 SFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALD 852
Query: 730 KFLDKL 747
FLDKL
Sbjct: 853 NFLDKL 858
>sp|P58252|EF2_MOUSE Elongation factor 2 (EF-2)
Length = 858
Score = 387 bits (993), Expect = e-107
Identities = 176/246 (71%), Positives = 205/246 (83%)
Frame = +1
Query: 10 LSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYL 189
L+ DID G+++AR E+K R RYL E Y+WDV E+RKIWCFGPDG GPN++ D++KGVQYL
Sbjct: 613 LAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYL 672
Query: 190 NEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTARRCFYAS 369
NEIKDSVVA F WATK+G LCEENMRGVRF++HDVTLHADAIHRGGGQIIPTARRC YAS
Sbjct: 673 NEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYAS 732
Query: 370 VLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNE 549
VLTA P L+EP+Y EIQ PE +GGIY LN++RG +F E QVAGTP +VVKAYLPVNE
Sbjct: 733 VLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNE 792
Query: 550 SFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLD 729
SF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P D S+P V +TRKRKGL E +P LD
Sbjct: 793 SFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALD 852
Query: 730 KFLDKL 747
FLDKL
Sbjct: 853 NFLDKL 858
>sp|P05086|EF2_MESAU Elongation factor 2 (EF-2)
Length = 858
Score = 387 bits (993), Expect = e-107
Identities = 176/246 (71%), Positives = 205/246 (83%)
Frame = +1
Query: 10 LSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYL 189
L+ DID G+++AR E+K R RYL E Y+WDV E+RKIWCFGPDG GPN++ D++KGVQYL
Sbjct: 613 LAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYL 672
Query: 190 NEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTARRCFYAS 369
NEIKDSVVA F WATK+G LCEENMRGVRF++HDVTLHADAIHRGGGQIIPTARRC YAS
Sbjct: 673 NEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYAS 732
Query: 370 VLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNE 549
VLTA P L+EP+Y EIQ PE +GGIY LN++RG +F E QVAGTP +VVKAYLPVNE
Sbjct: 733 VLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNE 792
Query: 550 SFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLD 729
SF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P D S+P V +TRKRKGL E +P LD
Sbjct: 793 SFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALD 852
Query: 730 KFLDKL 747
FLDKL
Sbjct: 853 NFLDKL 858
>sp|P05197|EF2_RAT Elongation factor 2 (EF-2)
Length = 858
Score = 387 bits (993), Expect = e-107
Identities = 176/246 (71%), Positives = 205/246 (83%)
Frame = +1
Query: 10 LSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYL 189
L+ DID G+++AR E+K R RYL E Y+WDV E+RKIWCFGPDG GPN++ D++KGVQYL
Sbjct: 613 LAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYL 672
Query: 190 NEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTARRCFYAS 369
NEIKDSVVA F WATK+G LCEENMRGVRF++HDVTLHADAIHRGGGQIIPTARRC YAS
Sbjct: 673 NEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYAS 732
Query: 370 VLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNE 549
VLTA P L+EP+Y EIQ PE +GGIY LN++RG +F E QVAGTP +VVKAYLPVNE
Sbjct: 733 VLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNE 792
Query: 550 SFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLD 729
SF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P D S+P V +TRKRKGL E +P LD
Sbjct: 793 SFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALD 852
Query: 730 KFLDKL 747
FLDKL
Sbjct: 853 NFLDKL 858
>sp|P09445|EF2_CRIGR Elongation factor 2 (EF-2)
Length = 858
Score = 380 bits (976), Expect = e-105
Identities = 174/246 (70%), Positives = 203/246 (82%)
Frame = +1
Query: 10 LSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYL 189
L+ DID G+++AR E+K R RYL E Y+WDV E+RKIWCFGPDG GPN++ D++KGVQYL
Sbjct: 613 LAEDIDKGEVSARQELKARARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYL 672
Query: 190 NEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTARRCFYAS 369
NEIKDSVVA F WATK+G LCEENMRGVRF++HDVTLHADAIHR GGQIIPTARRC YAS
Sbjct: 673 NEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRRGGQIIPTARRCLYAS 732
Query: 370 VLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNE 549
VLTA P L+EP+Y EIQ PE +GGIY LN++RG +F E QVAGTP +VVKAYLPVNE
Sbjct: 733 VLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNE 792
Query: 550 SFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLD 729
SF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P D S+ V +TRKRKGL E +P LD
Sbjct: 793 SFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRGSQVVAETRKRKGLKEGIPALD 852
Query: 730 KFLDKL 747
FLDKL
Sbjct: 853 NFLDKL 858
>sp|P29691|EF2_CAEEL Elongation factor 2 (EF-2)
Length = 852
Score = 376 bits (966), Expect = e-104
Identities = 177/246 (71%), Positives = 204/246 (82%)
Frame = +1
Query: 10 LSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYL 189
L+ DI+ G + AR E K R + L E Y++DVTE+RKIWCFGPDG GPNL++DV+KGVQYL
Sbjct: 607 LADDIEGGTVNARDEFKARAKILAEKYEYDVTEARKIWCFGPDGTGPNLLMDVTKGVQYL 666
Query: 190 NEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTARRCFYAS 369
NEIKDSVVA F WAT++GVL +ENMRGVRFN+HDVTLHADAIHRGGGQIIPTARR FYAS
Sbjct: 667 NEIKDSVVAGFQWATREGVLSDENMRGVRFNVHDVTLHADAIHRGGGQIIPTARRVFYAS 726
Query: 370 VLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNE 549
VLTA P LLEPVY EIQ PE A+GGIY LN+RRG +F E QV GTP +VVKAYLPVNE
Sbjct: 727 VLTAEPRLLEPVYLVEIQCPEAAVGGIYGVLNRRRGHVFEESQVTGTPMFVVKAYLPVNE 786
Query: 550 SFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLD 729
SF FT++LR+ TGGQAFPQCVFDHWQ+ PG+PL+ +KP V DTRKRKGL E VP LD
Sbjct: 787 SFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPLEAGTKPNQIVLDTRKRKGLKEGVPALD 846
Query: 730 KFLDKL 747
+LDK+
Sbjct: 847 NYLDKM 852
>sp|P13060|EF2_DROME Elongation factor 2 (EF-2)
Length = 844
Score = 371 bits (953), Expect = e-102
Identities = 171/246 (69%), Positives = 202/246 (82%)
Frame = +1
Query: 10 LSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQYL 189
L DID G ++A+ E K R RYL E YD+DVTE+RKIWCFGPDG GPN ++D +K VQYL
Sbjct: 599 LPEDIDNGDVSAKDEFKARARYLSEKYDYDVTEARKIWCFGPDGTGPNFILDCTKSVQYL 658
Query: 190 NEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTARRCFYAS 369
NEIKDSVVA F WA+K+G+L +EN+RGVRFNI+DVTLHADAIHRGGGQIIPT RRC YA+
Sbjct: 659 NEIKDSVVAGFQWASKEGILADENLRGVRFNIYDVTLHADAIHRGGGQIIPTTRRCLYAA 718
Query: 370 VLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPVNE 549
+TA P L+EPVY CEIQ PE A+GGIY LN+RRG +F E QV GTP +VVKAYLPVNE
Sbjct: 719 AITAKPRLMEPVYLCEIQCPEVAVGGIYGVLNRRRGHVFEENQVVGTPMFVVKAYLPVNE 778
Query: 550 SFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGITVKDTRKRKGLSEDVPLLD 729
SF FT++LR+ TGGQAFPQCVFDHWQ+ PG+P +P SKP V+DTRKRKGL E +P L
Sbjct: 779 SFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPSEPSSKPYAIVQDTRKRKGLKEGLPDLS 838
Query: 730 KFLDKL 747
++LDKL
Sbjct: 839 QYLDKL 844
>sp|Q6BJ25|EF2_DEBHA Elongation factor 2 (EF-2)
Length = 842
Score = 328 bits (840), Expect = 1e-89
Identities = 159/248 (64%), Positives = 187/248 (75%)
Frame = +1
Query: 4 EELSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQ 183
EE+S DI+ G I R + K R R L + + WDVT++RKIWCFGPDGNGPNLVVD +K VQ
Sbjct: 595 EEVSLDIEKGVINPRDDFKARARILADNHGWDVTDARKIWCFGPDGNGPNLVVDQTKAVQ 654
Query: 184 YLNEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTARRCFY 363
YLNEIKDSVVAAF WATK+G + EN+R VR NI DVTLHADAIHRGGGQIIPT RR Y
Sbjct: 655 YLNEIKDSVVAAFQWATKEGPIFGENVRSVRVNILDVTLHADAIHRGGGQIIPTMRRVTY 714
Query: 364 ASVLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPV 543
AS+L A P + EPV+ EIQ PE A+GGIYS LNK+RG + SE Q GTP + VKAYLPV
Sbjct: 715 ASMLLAEPAIQEPVFLVEIQCPENAIGGIYSVLNKKRGQVISEEQRPGTPLFTVKAYLPV 774
Query: 544 NESFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGITVKDTRKRKGLSEDVPL 723
NESF F+ ELR TGGQAFPQ +FDHW G+P DP SK G VK+ R+R+G+ DVP
Sbjct: 775 NESFGFSGELRQSTGGQAFPQLIFDHWANLNGDPTDPTSKVGTIVKEKRERQGMKPDVPG 834
Query: 724 LDKFLDKL 747
+++ DKL
Sbjct: 835 YEEYYDKL 842
>sp|O13430|EF2_CANAL Elongation factor 2 (EF-2)
Length = 842
Score = 322 bits (826), Expect = 5e-88
Identities = 159/248 (64%), Positives = 183/248 (73%)
Frame = +1
Query: 4 EELSSDIDAGKITARSEIKERGRYLVETYDWDVTESRKIWCFGPDGNGPNLVVDVSKGVQ 183
EE+S DI+ G I R + K R R L + + WDV ++RKIWCFGPDGNGPNLVVD +K VQ
Sbjct: 595 EEVSLDIENGVINPRDDFKARARILADKHGWDVVDARKIWCFGPDGNGPNLVVDQTKAVQ 654
Query: 184 YLNEIKDSVVAAFNWATKDGVLCEENMRGVRFNIHDVTLHADAIHRGGGQIIPTARRCFY 363
YLNEIKDSVVAAF WATK+G + EN R VR NI DVTLHADAIHRGGGQIIPT RR Y
Sbjct: 655 YLNEIKDSVVAAFQWATKEGPIFGENCRSVRVNILDVTLHADAIHRGGGQIIPTMRRVTY 714
Query: 364 ASVLTASPCLLEPVYQCEIQGPETALGGIYSTLNKRRGIIFSEMQVAGTPQYVVKAYLPV 543
AS+L A P + EPV+ EIQ PE A+GGIYS LNK+RG + SE Q GTP + VKAYLPV
Sbjct: 715 ASMLLAEPAIQEPVFLVEIQCPENAIGGIYSVLNKKRGQVISEEQRPGTPLFTVKAYLPV 774
Query: 544 NESFNFTSELRAQTGGQAFPQCVFDHWQLFPGNPLDPLSKPGITVKDTRKRKGLSEDVPL 723
NESF FT ELR TGGQAFPQ +FDHWQ+ G+ D SKPG VK+ R R GL +VP
Sbjct: 775 NESFGFTGELRQATGGQAFPQLIFDHWQVMSGDVTDENSKPGAIVKEKRVRAGLKPEVPE 834
Query: 724 LDKFLDKL 747
++ DKL
Sbjct: 835 YTEYYDKL 842
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,174,611
Number of Sequences: 369166
Number of extensions: 2032717
Number of successful extensions: 5166
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4852
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5024
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7260540000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)