Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_P03
(865 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8MJG1|PSIP1_BOVIN PC4 and SFRS1 interacting protein (Le... 53 1e-06
sp|Q99JF8|PSIP1_MOUSE PC4 and SFRS1 interacting protein (Le... 50 6e-06
sp|O75475|PSIP1_HUMAN PC4 and SFRS1 interacting protein (Le... 50 1e-05
sp|Q66T72|PSIP1_FELCA PC4 and SFRS1 interacting protein (Le... 49 1e-05
sp|Q812D1|PSIP1_RAT PC4 and SFRS1 interacting protein (Lens... 49 2e-05
sp|Q86SQ4|GP126_HUMAN Probable G-protein coupled receptor 1... 36 0.16
sp|Q6YQC6|TIG_ONYPE Trigger factor (TF) 35 0.21
sp|Q07896|NOC3_YEAST Nucleolar complex-associated protein 3 35 0.35
sp|Q90339|MYSS_CYPCA Myosin heavy chain, fast skeletal muscle 34 0.46
sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac muscle bet... 34 0.60
>sp|Q8MJG1|PSIP1_BOVIN PC4 and SFRS1 interacting protein (Lens epithelium-derived growth
factor)
Length = 483
Score = 53.1 bits (126), Expect = 1e-06
Identities = 40/166 (24%), Positives = 80/166 (48%), Gaps = 6/166 (3%)
Frame = +2
Query: 5 DIRSSLVLGKEDYKTCLERFKSLYEMQIDLLSLVKVWQLMDTVKKCRRYKRNEQIKQEAQ 184
+I++SL + D C+E L +Q+ + K +++ T+KK RR+K ++ I +++
Sbjct: 311 EIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKST 370
Query: 185 SVYKRFIDIYTHASKDEIATA---QTLLAQYRHQNNVQHQNVGVDSTNKSNGLSIPISVA 355
+Y +F +++ D + T ++L Q +H+ + ++ G NK
Sbjct: 371 MLYNKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKE---QTG 427
Query: 356 DMFQNRLSDSHPTKSQPQ---NSNKEESVNVNAVSTVNPATDNLES 484
N SD+ + +QPQ +SN+E N A S P+++ E+
Sbjct: 428 SKTLNGGSDAQDS-NQPQHNGDSNEESKDNHEASSKKKPSSEERET 472
>sp|Q99JF8|PSIP1_MOUSE PC4 and SFRS1 interacting protein (Lens epithelium-derived growth
factor)
Length = 528
Score = 50.4 bits (119), Expect = 6e-06
Identities = 40/180 (22%), Positives = 76/180 (42%), Gaps = 2/180 (1%)
Frame = +2
Query: 5 DIRSSLVLGKEDYKTCLERFKSLYEMQIDLLSLVKVWQLMDTVKKCRRYKRNEQIKQEAQ 184
+I++SL + D C+E L +Q+ + K +++ T+KK RR+K ++ I +++
Sbjct: 356 EIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKST 415
Query: 185 SVYKRFIDIYTHASKDEIATAQTLLAQYRHQNNVQHQNVGVDSTNKSNGLSIPISVADMF 364
+Y +F +++ D + T Q L Q + N D K
Sbjct: 416 MLYNKFKNMFLVGEGDSVIT-QVLNKSLAEQRQHEEANKTKDQGKKG------------- 461
Query: 365 QNRLSDSHP--TKSQPQNSNKEESVNVNAVSTVNPATDNLESSKPRVAPPTEEKMRLLSI 538
N+ + P TKS S+ +ES + N + + + PP EE+ +S+
Sbjct: 462 PNKKLEKEPTGTKSLNGGSDAQESNHPQHNGDSNEDGKDSREASSKTKPPGEEREAEISL 521
>sp|O75475|PSIP1_HUMAN PC4 and SFRS1 interacting protein (Lens epithelium-derived growth
factor) (Transcriptional coactivator p75/p52) (Dense
fine speckles 70 kDa protein) (DFS 70) (CLL-associated
antigen KW-7)
Length = 530
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/166 (22%), Positives = 79/166 (47%), Gaps = 6/166 (3%)
Frame = +2
Query: 5 DIRSSLVLGKEDYKTCLERFKSLYEMQIDLLSLVKVWQLMDTVKKCRRYKRNEQIKQEAQ 184
+I++SL + D C+E L +Q+ + K +++ T+KK RR+K ++ I +++
Sbjct: 358 EIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKST 417
Query: 185 SVYKRFIDIYTHASKDEIATA---QTLLAQYRHQNNVQHQNVGVDSTNKSNGLSIPISVA 355
+Y +F +++ D + T ++L Q +H+ + ++ G NK
Sbjct: 418 MLYNKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKE---QTG 474
Query: 356 DMFQNRLSDSHPTKSQPQN---SNKEESVNVNAVSTVNPATDNLES 484
N SD+ +QPQ+ SN++ N A + P+++ E+
Sbjct: 475 SKTLNGGSDAQ-DGNQPQHNGESNEDSKDNHEASTKKKPSSEERET 519
>sp|Q66T72|PSIP1_FELCA PC4 and SFRS1 interacting protein (Lens epithelium-derived growth
factor) (Transcription coactivator p75) (LEDGF/p75)
Length = 530
Score = 49.3 bits (116), Expect = 1e-05
Identities = 36/165 (21%), Positives = 73/165 (44%), Gaps = 19/165 (11%)
Frame = +2
Query: 5 DIRSSLVLGKEDYKTCLERFKSLYEMQIDLLSLVKVWQLMDTVKKCRRYKRNEQIKQEAQ 184
+I++SL + D C+E L +Q+ + K +++ T+KK RR+K ++ I +++
Sbjct: 358 EIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQIIMEKST 417
Query: 185 SVYKRFIDIYTHASKDEIATA---QTLLAQYRHQNNVQHQNVGVDSTNK----------- 322
+Y +F +++ D + T ++L Q +H+ + ++ G NK
Sbjct: 418 MLYNKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLDKEQTGSKT 477
Query: 323 -SNGLSIPISVADMFQNRLS----DSHPTKSQPQNSNKEESVNVN 442
+ G P S S D H S+ + SN+E ++
Sbjct: 478 LNGGSDAPDSNQAQHNGDSSEESKDKHEASSKKKPSNEERETEIS 522
>sp|Q812D1|PSIP1_RAT PC4 and SFRS1 interacting protein (Lens epithelium-derived growth
factor)
Length = 528
Score = 48.5 bits (114), Expect = 2e-05
Identities = 26/109 (23%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Frame = +2
Query: 5 DIRSSLVLGKEDYKTCLERFKSLYEMQIDLLSLVKVWQLMDTVKKCRRYKRNEQIKQEAQ 184
+I++SL + D C+E L +Q+ + K +++ T+KK RR+K ++ I +++
Sbjct: 356 EIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKST 415
Query: 185 SVYKRFIDIYTHASKDEIATA---QTLLAQYRHQNNVQHQNVGVDSTNK 322
+Y +F +++ D + T ++L Q +H+ + ++ G NK
Sbjct: 416 MLYNKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNK 464
>sp|Q86SQ4|GP126_HUMAN Probable G-protein coupled receptor 126 precursor
Length = 1221
Score = 35.8 bits (81), Expect = 0.16
Identities = 32/94 (34%), Positives = 51/94 (54%), Gaps = 4/94 (4%)
Frame = +2
Query: 416 NKEESVNVNAVST-VNPATDNLESSKPRVAPPTEEKMRLLSIDLEAKVSDILNKIEKNVD 592
NKEES+++ ST +N ++ L SS + + E ++ +ID A D+ + N+
Sbjct: 618 NKEESIDITLGSTLMNIFSNILSSSDSDLLESSSEALK--TIDELAFKIDLNSTSHVNIT 675
Query: 593 VMN-QKSLSHLLPSTD--ENFSITLPSQWKSVNE 685
N S+S LLP T+ NFSI LPS +S ++
Sbjct: 676 TRNLALSVSSLLPGTNAISNFSIGLPSNNESYSQ 709
>sp|Q6YQC6|TIG_ONYPE Trigger factor (TF)
Length = 430
Score = 35.4 bits (80), Expect = 0.21
Identities = 32/139 (23%), Positives = 55/139 (39%), Gaps = 11/139 (7%)
Frame = +2
Query: 242 TAQTLLAQYRHQNNVQHQNVGVDSTNKSNGLSIPISVADMFQNRLSDSHPTKSQPQNSNK 421
T QTLLAQ +H+ + ++ K++ L IP + Q RL + + QN
Sbjct: 275 TKQTLLAQKKHKEKENVEKQVIEQLVKNSELEIPQEIVSQEQIRLQKEFEAQLKQQNLTL 334
Query: 422 EESVNVNAVST-------VNPATDNLESSKPRVAPPTEEKMRLLSIDLEAKVSDILNKIE 580
E+ + A N+E +EK+ + +E K ++ N +
Sbjct: 335 EQYKQYLGIDDEKMEKEFSQQAQKNIEYQLIMEQVAAQEKLTISQEKIEQKYQNLSNHYK 394
Query: 581 KNVDVMNQ----KSLSHLL 625
V+ + Q K+L H L
Sbjct: 395 VPVNQIKQNLPEKNLKHSL 413
>sp|Q07896|NOC3_YEAST Nucleolar complex-associated protein 3
Length = 663
Score = 34.7 bits (78), Expect = 0.35
Identities = 28/126 (22%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Frame = +2
Query: 308 DSTNKSNGLSIPISVADMFQNRLSDSHPTKSQPQNSNKEESVNVNAVSTVNPATDNLESS 487
D++N GL PI V + +L H + +P++ ++E+ + ++ + E+
Sbjct: 68 DTSNLVEGL--PIKVNGKVERKL---HKAQEKPKDDDEEDEDSNDSSEDDEGPNEEQEAE 122
Query: 488 KPRVAPPTEEKMRLLSIDLEAKVSDILNKIEKNVDVMNQ--KSLSHLLPSTDENFSITLP 661
P TEEK+ L D+ V+ ++ + E+N + + K + P+T + + L
Sbjct: 123 AKEDEPDTEEKILQLKEDIADLVTKVMEEPEENTAALGRLCKMVESKNPNTCKFSMLALV 182
Query: 662 SQWKSV 679
+KS+
Sbjct: 183 PVFKSI 188
>sp|Q90339|MYSS_CYPCA Myosin heavy chain, fast skeletal muscle
Length = 1935
Score = 34.3 bits (77), Expect = 0.46
Identities = 44/228 (19%), Positives = 103/228 (45%), Gaps = 20/228 (8%)
Frame = +2
Query: 32 KEDYKTCLERFKSLYEMQIDLLSL--VKVWQLMDTVKKCRRYKRNEQIKQEAQSV---YK 196
++++ +ER +S+Y +Q ++ S VK W M K + ++ + ++E ++ Y+
Sbjct: 799 RKEFVKMMERRESIYSIQYNIRSFMNVKHWPWMKLYFKIKPLLKSAETEKEMAAMKENYE 858
Query: 197 RFIDIYTHASKDEIATAQTLLAQYRHQNNVQHQNVGVDSTNKSNGLSIPISVADMFQNRL 376
+ + T A + + +++ + +N++Q Q V +S N S+ + ++++
Sbjct: 859 KMKEDLTKALAKKKELEEKMVSLLQEKNDLQLQ-VTAESENLSDAEE---RCEGLIKSKI 914
Query: 377 SDSHPTKSQPQNSNKEESVNV----------NAVSTVNPATDNLESSKPRVAP---PTEE 517
K + EE +N + S + D+LE + +V TE
Sbjct: 915 QLEAKLKETNERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 974
Query: 518 KMRLLSIDLEAKVSDI--LNKIEKNVDVMNQKSLSHLLPSTDENFSIT 655
K++ L+ ++ ++ I L K +K + +Q++L L D+ ++T
Sbjct: 975 KVKNLTEEMASQDESIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLT 1022
>sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta)
Length = 1935
Score = 33.9 bits (76), Expect = 0.60
Identities = 49/239 (20%), Positives = 104/239 (43%), Gaps = 21/239 (8%)
Frame = +2
Query: 2 VDIRSSLVLGKEDYKTCLERFKSLYEMQIDLLSL--VKVWQLMDTVKKCRRYKRNEQIKQ 175
+ +S VL + +YK LER SL +Q ++ + VK W M K + ++ + ++
Sbjct: 788 IQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREK 847
Query: 176 EAQSVYKRFIDIYTHASKDEI---ATAQTLLAQYRHQNNVQHQNVGVDSTNKSNGLSIPI 346
E S+ + F + K E + +++ + +N++Q Q V + N ++
Sbjct: 848 EMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQ-VQAEQDNLADAEE--- 903
Query: 347 SVADMFQNRLSDSHPTKSQPQNSNKEESVNV----------NAVSTVNPATDNLESSKPR 496
+ +N++ K + EE +N + S + D+LE + +
Sbjct: 904 RCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK 963
Query: 497 VAP---PTEEKMRLLSIDLEAKVSDILNKIEKNVDVM---NQKSLSHLLPSTDENFSIT 655
V TE K++ L+ ++ A + +I+ K+ K + +Q++L L D+ ++T
Sbjct: 964 VEKEKHATENKVKNLTEEM-AGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLT 1021
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,161,032
Number of Sequences: 369166
Number of extensions: 1876525
Number of successful extensions: 5766
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5525
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5759
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8582957970
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)