Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_O03
(804 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9U7E0|ATRX_CAEEL Transcriptional regulator ATRX homolog... 45 2e-04
sp|O01761|UNC89_CAEEL Muscle M-line assembly protein unc-89... 40 0.006
sp|Q14978|NOLC1_HUMAN Nucleolar phosphoprotein p130 (Nucleo... 39 0.022
sp|P32257|GAL11_KLULA Transcription regulatory protein GAL11 37 0.048
sp|P19246|NFH_MOUSE Neurofilament triplet H protein (200 kD... 35 0.24
sp|Q9NR30|DDX21_HUMAN Nucleolar RNA helicase II (Nucleolar ... 34 0.41
sp|Q95208|ICAL_SHEEP Calpastatin (Calpain inhibitor) 34 0.41
sp|P15205|MAP1B_RAT Microtubule-associated protein 1B (MAP ... 34 0.53
sp|P14873|MAP1B_MOUSE Microtubule-associated protein 1B (MA... 34 0.53
sp|Q9Y6V0|PCLO_HUMAN Piccolo protein (Aczonin) 33 0.70
>sp|Q9U7E0|ATRX_CAEEL Transcriptional regulator ATRX homolog (X-linked nuclear protein 1)
Length = 1359
Score = 45.1 bits (105), Expect = 2e-04
Identities = 44/187 (23%), Positives = 75/187 (40%), Gaps = 1/187 (0%)
Frame = +3
Query: 15 SKPKKQTKTQSFEEPSLEDQDPPPENIKKPKKQHSKASRPTEVLSDDGINPQPDYSKPLK 194
+K K K E S ED+ P ++ KK K+ +K+ +E + + SK +
Sbjct: 171 NKEKSVKKRAETSEESDEDEKPSKKS-KKGLKKKAKSESESESEDEKEVKKSKKKSKKVV 229
Query: 195 KQPSRTRSKXXXXXXXXXXXYSKPLKKQNSKPSRSIEELSDGEN-PQPIYAXXXXXXXXX 371
K+ S + + SK +++S+ +S EE + E+ P+P
Sbjct: 230 KKESESEDEAPEKKKTEKRKRSKTSSEESSESEKSDEEEEEKESSPKP----KKKKPLAV 285
Query: 372 XXRPNDDLSDEGFVPTIPQVRLSAKVDSSLSFPDPPMDSSHSEELDPPPKASKKKGNHKP 551
+D+ S+E V +PQ + V D S SE D K SKKK +
Sbjct: 286 KKLSSDEESEESDVEVLPQKKKRGAVTLISDSEDEKDQKSESEASDVEEKVSKKKAKKQE 345
Query: 552 NPASSAN 572
+ S ++
Sbjct: 346 SSESGSD 352
Score = 33.5 bits (75), Expect = 0.70
Identities = 35/171 (20%), Positives = 55/171 (32%)
Frame = +3
Query: 24 KKQTKTQSFEEPSLEDQDPPPENIKKPKKQHSKASRPTEVLSDDGINPQPDYSKPLKKQP 203
KK+ + S ED+D E +K KK+ K + T S + + K K +
Sbjct: 114 KKEKSKKKRTTSSSEDEDSDEEREQKSKKKSKKTKKQTSSESSEESEEERKVKKSKKNKE 173
Query: 204 SRTRSKXXXXXXXXXXXYSKPLKKQNSKPSRSIEELSDGENPQPIYAXXXXXXXXXXXRP 383
+ + KP KK + + S+ E+ +
Sbjct: 174 KSVKKRAETSEESDED--EKPSKKSKKGLKKKAKSESESESEDEKEVKKSKKKSKKVVKK 231
Query: 384 NDDLSDEGFVPTIPQVRLSAKVDSSLSFPDPPMDSSHSEELDPPPKASKKK 536
+ DE + R +K S S D EE + PK KKK
Sbjct: 232 ESESEDEAPEKKKTEKRKRSKTSSEESSESEKSD-EEEEEKESSPKPKKKK 281
>sp|O01761|UNC89_CAEEL Muscle M-line assembly protein unc-89 (Uncoordinated protein 89)
Length = 8081
Score = 40.4 bits (93), Expect = 0.006
Identities = 45/194 (23%), Positives = 69/194 (35%), Gaps = 8/194 (4%)
Frame = +3
Query: 18 KPKKQTKTQ-SFEEPSLEDQDPPPENIKKPKKQHSKASRPTEVLSDDGINPQPDYSKPLK 194
KPK TK + S E+ + ED P + K P+K K + PT+ S + P K
Sbjct: 1630 KPKSPTKKEKSPEKSATEDVKSPTKKEKSPEKVEEKPTSPTKKESSPTKKTDDEVKSPTK 1689
Query: 195 KQ--PSRTRSKXXXXXXXXXXXYSKPLKKQNSKPSRSIEELSDGENPQPIYAXXXXXXXX 368
K+ P K + P KK+ S +EE+ + P A
Sbjct: 1690 KEKSPQTVEEKP-----------ASPTKKEKSPEKSVVEEVKSPKEKSPEKAEEKPKSPT 1738
Query: 369 XXXR-PNDDLSDEGFVPT----IPQVRLSAKVDSSLSFPDPPMDSSHSEELDPPPKASKK 533
+ P ++E PT P+ K S P+ + +E+ P K K
Sbjct: 1739 KKEKSPEKSAAEEVKSPTKKEKSPEKSAEEKPKSPTKKESSPVKMA-DDEVKSPTKKEKS 1797
Query: 534 KGNHKPNPASSANR 575
+ PAS +
Sbjct: 1798 PEKVEEKPASPTKK 1811
Score = 37.0 bits (84), Expect = 0.063
Identities = 38/186 (20%), Positives = 65/186 (34%), Gaps = 3/186 (1%)
Frame = +3
Query: 27 KQTKTQSFEEPSLEDQDPPPENIKKPKKQHSKASRPTEVLSDDGINPQPDYSKPLKKQPS 206
K K +S P+ +++ P E +K P K+ S PT+ + + +K P
Sbjct: 1405 KSPKEKSPASPTKKEKSPAAEEVKSPTKKEKSPSSPTKKEKSPSSPTKKTGDEVKEKSPP 1464
Query: 207 RTRSKXXXXXXXXXXXYSKPLKKQNSKPSRSIEELSDGENPQPIYAXXXXXXXXXXXRPN 386
++ +K S P+KK+ S + +I E+S +
Sbjct: 1465 KSPTKKEKSPEKPEDVKS-PVKKEKSPDATNIVEVSSETTIEKTETTMTTEMTHESEESR 1523
Query: 387 DDLSDEGFVPTIPQVRLSAKVDSSLSFP---DPPMDSSHSEELDPPPKASKKKGNHKPNP 557
+ E + KVD P D + S +EE+ P K K + P
Sbjct: 1524 TSVKKE---------KTPEKVDEKPKSPTKKDKSPEKSITEEIKSPVKKEKSPEKVEEKP 1574
Query: 558 ASSANR 575
AS +
Sbjct: 1575 ASPTKK 1580
Score = 30.8 bits (68), Expect = 4.5
Identities = 26/99 (26%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Frame = +3
Query: 15 SKPKKQTKTQSFEE----PSLEDQDPPP---ENIKKPKKQHSKASRPTEVLSDDGINPQP 173
S KK+ + EE P+ +++ P E +K P K+ S PT+ D+ P
Sbjct: 1790 SPTKKEKSPEKVEEKPASPTKKEKTPEKSAAEELKSPTKKEKSPSSPTKKTGDESKEKSP 1849
Query: 174 DYSKPLKKQPSRTRSKXXXXXXXXXXXYSKPLKKQNSKP 290
+ KP +K S T K P KK++ P
Sbjct: 1850 E--KPEEKPKSPTPKKSPP---------GSPKKKKSKSP 1877
Score = 30.0 bits (66), Expect = 7.7
Identities = 42/219 (19%), Positives = 76/219 (34%), Gaps = 6/219 (2%)
Frame = +3
Query: 24 KKQTKTQSFEEPSLEDQDPPPENIKKPKKQHSKASRPTEVLSDDGINPQPDYSKPLKKQ- 200
K TK + E S+ ++ P+ K P+K K PT+ + D P KK+
Sbjct: 1599 KSPTKKEKSPEKSVVEELKSPKE-KSPEKADDKPKSPTKKEKSPEKSATEDVKSPTKKEK 1657
Query: 201 -PSRTRSKXXXXXXXXXXXYSKPLKKQNSKPSRSIEELSD----GENPQPIYAXXXXXXX 365
P + K + P KK++S ++ +E+ ++PQ +
Sbjct: 1658 SPEKVEEKP-----------TSPTKKESSPTKKTDDEVKSPTKKEKSPQTV-EEKPASPT 1705
Query: 366 XXXXRPNDDLSDEGFVPTIPQVRLSAKVDSSLSFPDPPMDSSHSEELDPPPKASKKKGNH 545
P + +E P + + S + + + S +EE+ P K K
Sbjct: 1706 KKEKSPEKSVVEEVKSPKEKSPEKAEEKPKSPTKKEKSPEKSAAEEVKSPTKKEK----- 1760
Query: 546 KPNPASSANRXXXXXXXXXXXXXXXXXXQIRSNTSSERS 662
+P SA +++S T E+S
Sbjct: 1761 --SPEKSAEEKPKSPTKKESSPVKMADDEVKSPTKKEKS 1797
>sp|Q14978|NOLC1_HUMAN Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa
nucleolar phosphoprotein) (Nopp140) (Nucleolar and
coiled-body phosphoprotein 1)
Length = 699
Score = 38.5 bits (88), Expect = 0.022
Identities = 49/208 (23%), Positives = 70/208 (33%), Gaps = 19/208 (9%)
Frame = +3
Query: 3 QAGYSKPKKQTKTQSFEEPSLEDQDP------------------PPENIKK-PKKQHSKA 125
+A + PKK + S + S ED+ P PP+ + PK + KA
Sbjct: 155 KAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKA 214
Query: 126 SRPTEVLSDDGINPQPDYSKPLKKQPSRTRSKXXXXXXXXXXXYSKPLKKQNSKPSRSIE 305
+ + S + + K P +T K + P +K +S S +
Sbjct: 215 ASSSSSSSSSSSSDDSEEEKAAAT-PKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSD 273
Query: 306 ELSDGENPQPIYAXXXXXXXXXXXRPNDDLSDEGFVPTIPQVRLSAKVDSSLSFPDPPMD 485
E + E +P+ G P V V+SS D D
Sbjct: 274 E--EEEQKKPMKNKPGPYSYAPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDES-D 330
Query: 486 SSHSEELDPPPKASKKKGNHKPNPASSA 569
SS EE PP KA K KP PA A
Sbjct: 331 SSSEEEKKPPTKAVVSKATTKPPPAKKA 358
>sp|P32257|GAL11_KLULA Transcription regulatory protein GAL11
Length = 1034
Score = 37.4 bits (85), Expect = 0.048
Identities = 18/47 (38%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Frame = +3
Query: 6 AGYSKPKKQTKTQSFEEPSLEDQDPPPENIKKPKKQHSKAS--RPTE 140
AG KP+ Q Q+ ++P ++ Q PP ++ ++Q SK S RPTE
Sbjct: 454 AGVMKPQPQQTPQNIQQPMMQQQSSPPPQQQQQQQQQSKISVPRPTE 500
>sp|P19246|NFH_MOUSE Neurofilament triplet H protein (200 kDa neurofilament protein)
(Neurofilament heavy polypeptide) (NF-H)
Length = 1087
Score = 35.0 bits (79), Expect = 0.24
Identities = 25/104 (24%), Positives = 42/104 (40%)
Frame = +3
Query: 21 PKKQTKTQSFEEPSLEDQDPPPENIKKPKKQHSKASRPTEVLSDDGINPQPDYSKPLKKQ 200
P+ QT Q EE ++ PPE +K P K+ +K+ E + + + P+ K K
Sbjct: 832 PEAQTPVQ--EEATVPTDIRPPEQVKSPAKEKAKSPEKEEAKTSEKVAPK----KEEVKS 885
Query: 201 PSRTRSKXXXXXXXXXXXYSKPLKKQNSKPSRSIEELSDGENPQ 332
P + K + P K +K S+ E + P+
Sbjct: 886 PVKEEVKAKEPPKKVEEEKTLPTPKTEAKESKKDEAPKEAPKPK 929
>sp|Q9NR30|DDX21_HUMAN Nucleolar RNA helicase II (Nucleolar RNA helicase Gu) (RH II/Gu)
(Gu-alpha) (DEAD-box protein 21)
Length = 783
Score = 34.3 bits (77), Expect = 0.41
Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
Frame = +3
Query: 15 SKPKKQTKTQSFEEPSLEDQDPP-PENIKKPKKQHSKASRPTEVLSDDGINPQPD 176
SK KK TK EEPS E+ D P P+ +KK K+ + + + L + +P+PD
Sbjct: 109 SKTKKVTKN---EEPSEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPD 160
>sp|Q95208|ICAL_SHEEP Calpastatin (Calpain inhibitor)
Length = 723
Score = 34.3 bits (77), Expect = 0.41
Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Frame = +3
Query: 12 YSKPKKQTKTQSFE-EPSLEDQDPPPENIKKPKKQHSKASRPTEVLSDDGINPQPDYSKP 188
+S KK+ K Q+ + EP + Q P + + K Q K TE S QP
Sbjct: 19 HSPNKKRHKKQAVKTEPEKKSQSTKPSVVHEKKTQEVKPKEHTEPKS------QP----- 67
Query: 189 LKKQPSRTRSKXXXXXXXXXXXYSKPLKKQNSKP-SRSIEELSDG 320
K PS TRSK +P ++++KP ++S +E+S G
Sbjct: 68 --KHPSDTRSKHAPKEKAVSKSSEQPPSEKSTKPKTKSQDEISGG 110
>sp|P15205|MAP1B_RAT Microtubule-associated protein 1B (MAP 1B) (Neuraxin) [Contains: MAP1
light chain LC1]
Length = 2459
Score = 33.9 bits (76), Expect = 0.53
Identities = 30/118 (25%), Positives = 46/118 (38%), Gaps = 9/118 (7%)
Frame = +3
Query: 18 KPKKQTKTQSFEEPSLEDQDPPPENIKKPKKQHSKASRPTEVLSD-DGINPQPDYSKPLK 194
KPKK+ + + P +D+ P E KK K+ K E+ + P D K +K
Sbjct: 652 KPKKEVAKKEDKTPLKKDEKPKKEEAKKEIKKEIKKEEKKELKKEVKKETPLKDAKKEVK 711
Query: 195 KQPSRTRSKXXXXXXXXXXXYSKPLKK-----QNSKPSRSIEELSDGENP---QPIYA 344
K + K SK +KK KP+ +++ E P +PI A
Sbjct: 712 KDEKKEVKKEEKEPKKEIKKISKDIKKSTPLSDTKKPAALKPKVAKKEEPTKKEPIAA 769
Score = 32.0 bits (71), Expect = 2.0
Identities = 20/100 (20%), Positives = 49/100 (49%)
Frame = +3
Query: 15 SKPKKQTKTQSFEEPSLEDQDPPPENIKKPKKQHSKASRPTEVLSDDGINPQPDYSKPLK 194
+KP+++ + + +E + ++ P + +KPKK+ +K E+ ++ + + K +K
Sbjct: 643 TKPEEKKEEKPKKEVAKKEDKTPLKKDEKPKKEEAKKEIKKEIKKEE----KKELKKEVK 698
Query: 195 KQPSRTRSKXXXXXXXXXXXYSKPLKKQNSKPSRSIEELS 314
K+ +K K +KK+ +P + I+++S
Sbjct: 699 KETPLKDAKKEVKKDE-----KKEVKKEEKEPKKEIKKIS 733
>sp|P14873|MAP1B_MOUSE Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X))
[Contains: MAP1 light chain LC1]
Length = 2464
Score = 33.9 bits (76), Expect = 0.53
Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Frame = +3
Query: 18 KPKKQTKTQSFEEPSLEDQDPPPENIKKPKKQHSKASRPTEVLSD-DGINPQPDYSKPLK 194
KPKK+ + + P +D+ P E +KK K+ K E+ + P D K +K
Sbjct: 653 KPKKEVVKKEDKTPLKKDEKPRKEEVKKEIKKEIKKEERKELKKEVKKETPLKDAKKEVK 712
Query: 195 KQPSRTRSKXXXXXXXXXXXYSKPLKK 275
K+ + K SK +KK
Sbjct: 713 KEEKKEVKKEEKEPKKEIKKISKDIKK 739
>sp|Q9Y6V0|PCLO_HUMAN Piccolo protein (Aczonin)
Length = 5183
Score = 33.5 bits (75), Expect = 0.70
Identities = 42/175 (24%), Positives = 65/175 (37%), Gaps = 2/175 (1%)
Frame = +3
Query: 51 EEPSL-EDQDPPPENIKKPKKQHSKASRPTEVLSDDGINPQPDYSKPLKKQPSRTRSKXX 227
+EPS+ +QD P KPK Q T+++S +PD P K S+ K
Sbjct: 682 KEPSVPSEQDKAPVADDKPK-QPKMVKPTTDLVSSSSATTKPDI--PSSKVQSQAEEKT- 737
Query: 228 XXXXXXXXXYSKPLKKQNSKPSRSIEELSDGENPQPIYAXXXXXXXXXXXRPNDDLSDEG 407
+ PLK ++KPS+S + P A
Sbjct: 738 ----------TPPLKTDSAKPSQSFPPTGEKVTPFDSKA--------------------- 766
Query: 408 FVPTIPQVRLSAKVDSSLSFPDPPMDSSHSEELDPPPKASK-KKGNHKPNPASSA 569
IP+ +K+ +S P P +S +++DP K + KK K +P A
Sbjct: 767 ----IPRPASDSKI---ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 814
Score = 30.0 bits (66), Expect = 7.7
Identities = 45/186 (24%), Positives = 65/186 (34%), Gaps = 7/186 (3%)
Frame = +3
Query: 33 TKTQSFEEPSLEDQDPPPENIKKPKKQHSKASRPTEVLSDDGINPQPDYSKPLKKQPSRT 212
T T + + S + Q P+ PK+ SKA P+P PL KQP+
Sbjct: 613 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKA-------------PEPKKPPPLVKQPTLH 659
Query: 213 RS-KXXXXXXXXXXXYSKPL-KKQNSKPSRSIE-ELSDGENPQPIYAXXXXXXXXXXXRP 383
S SKP K+ S PS + ++D + QP +P
Sbjct: 660 GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP-----------KMVKP 708
Query: 384 NDDLSDEGFVPTIPQVRLSAKVDSSLSFPDPPM--DSSHSEELDPP--PKASKKKGNHKP 551
DL T P + S + PP+ DS+ + PP K + P
Sbjct: 709 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVTPFDSKAIP 768
Query: 552 NPASSA 569
PAS +
Sbjct: 769 RPASDS 774
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,100,101
Number of Sequences: 369166
Number of extensions: 1532288
Number of successful extensions: 5911
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5206
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5813
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7618580670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)