Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_N13
(830 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O01393|UNC9_CAEEL Innexin unc-9 (Uncoordinated protein 9) 155 2e-37
sp|Q03412|UNC7_CAEEL Innexin unc-7 (Uncoordinated protein 7) 139 7e-33
sp|Q23157|INX11_CAEEL Innexin-11 130 6e-30
sp|Q19746|INX3_CAEEL Innexin-3 128 2e-29
sp|O01634|INX12_CAEEL Innexin-12 122 2e-27
sp|Q23027|INX5_CAEEL Innexin-5 115 1e-25
sp|Q22549|INX10_CAEEL Innexin-10 108 1e-23
sp|O61788|INX17_CAEEL Innexin-17 (Gap junction innexin) 103 8e-22
sp|Q27295|EAT5_CAEEL Innexin eat-5 97 4e-20
sp|Q21123|INX7_CAEEL Innexin-7 93 8e-19
>sp|O01393|UNC9_CAEEL Innexin unc-9 (Uncoordinated protein 9)
Length = 386
Score = 155 bits (391), Expect = 2e-37
Identities = 73/183 (39%), Positives = 114/183 (62%)
Frame = -1
Query: 827 YILMKFLYGINVIGQLFLMKKFLGFNSSMSSFGYTILSNIADGKEWHQTGIFPRVTYCYI 648
YI +K LY +N++GQ+FL+ FLG S +G +L+++ +G+EW ++G FPRVT C
Sbjct: 199 YISVKILYTVNIVGQIFLLNTFLGNRSKW--YGLQVLNDLMNGREWEESGHFPRVTLCDF 256
Query: 647 GEIKHLGASNKYVGQCALPINMLNEKIYVFLWFWVFIVGIITAISIPMWFFRIAILSRRS 468
E+K LG +++ QC L INM NEKI++FLWFW F++ T S+ W + + SR+
Sbjct: 257 -EVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQL 315
Query: 467 KFIKKFLMMHQSYNRSEKQLINSFIREFLRHDGVFLIRMICINAGDIVTADIVNRLWEIY 288
F+ K+L + Y + Q + F+ FLR DGVFL+RM+ +AG++ ++ LW Y
Sbjct: 316 NFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNY 375
Query: 287 KEN 279
+N
Sbjct: 376 CDN 378
>sp|Q03412|UNC7_CAEEL Innexin unc-7 (Uncoordinated protein 7)
Length = 522
Score = 139 bits (351), Expect = 7e-33
Identities = 69/181 (38%), Positives = 111/181 (61%), Gaps = 3/181 (1%)
Frame = -1
Query: 827 YILMKFLYGINVIGQLFLMKKFLGFNSSMSSFGYTILSNIADGKEWHQTGIFPRVTYCYI 648
YI +K LY NV+ Q FL+ LG N ++G+++L ++ EW QTG+FPRVT C
Sbjct: 322 YIGIKVLYSANVLLQFFLLNHLLGSNDL--AYGFSLLKDLMHAIEWEQTGMFPRVTLCDF 379
Query: 647 GEIKHLGASNKYVGQCALPINMLNEKIYVFLWFWVFIVGIITAISIPMWFFRIAILSRRS 468
E++ LG +++ QC L INM NEKI++FLWFW GI+T + W + I S+
Sbjct: 380 -EVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGM 438
Query: 467 KFIKKFLMM---HQSYNRSEKQLINSFIREFLRHDGVFLIRMICINAGDIVTADIVNRLW 297
F++K+L + H + ++ + F FLR DGVF++RMI +AG++++++++ LW
Sbjct: 439 SFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALW 498
Query: 296 E 294
+
Sbjct: 499 Q 499
>sp|Q23157|INX11_CAEEL Innexin-11
Length = 465
Score = 130 bits (326), Expect = 6e-30
Identities = 69/210 (32%), Positives = 111/210 (52%), Gaps = 6/210 (2%)
Frame = -1
Query: 827 YILMKFLYGINVIGQLFLMKKFLGFNSSMSSFGYTILSNIADGKEWHQTGIFPRVTYCYI 648
Y+ K LY +NV QL+LM FLG N +G+ ++ +I G+ W ++G FPR C
Sbjct: 202 YLFTKVLYFLNVFAQLYLMNYFLGTNRH-HWYGFGVVQDIVQGEPWERSGYFPRAAVCDF 260
Query: 647 GEIKHLGASNKYVGQCALPINMLNEKIYVFLWFWVFIVGIITAISIPMWFFRIAILSRRS 468
E++ + +Y QC L IN+ NEKI+V LWFW I+ + + +S+ WF +
Sbjct: 261 -EVRQVANIQRYSVQCVLVINIFNEKIFVLLWFWYVILLLSSTVSLVQWFIVLVFPCFSK 319
Query: 467 KFIKKFLMM------HQSYNRSEKQLINSFIREFLRHDGVFLIRMICINAGDIVTADIVN 306
F+K+ L + +Q +R E ++ F+ ++L DGVF++RM+ +AG I D+V
Sbjct: 320 WFVKQHLALSTLQNFNQRNSRREDSDVSKFVTQYLHKDGVFVLRMVSSHAGIIFATDLVQ 379
Query: 305 RLWEIYKENYKHMDFLNFSAYPKSMDVTTG 216
L+E Y K+ D ++TG
Sbjct: 380 ALYEAYDFQDKNKDVQGSPVSDDLQTISTG 409
>sp|Q19746|INX3_CAEEL Innexin-3
Length = 420
Score = 128 bits (322), Expect = 2e-29
Identities = 69/186 (37%), Positives = 107/186 (57%)
Frame = -1
Query: 827 YILMKFLYGINVIGQLFLMKKFLGFNSSMSSFGYTILSNIADGKEWHQTGIFPRVTYCYI 648
YI +K +Y NV Q ++ KFLG + + +G+ +++ G+EW +G+FPRVT C
Sbjct: 195 YICIKLMYLANVFVQFIILNKFLGNETFL--WGFHTFADLYAGREWQDSGVFPRVTLCDF 252
Query: 647 GEIKHLGASNKYVGQCALPINMLNEKIYVFLWFWVFIVGIITAISIPMWFFRIAILSRRS 468
++ L ++Y QC L INM NEKIY+F+WFW V I T I+ +R++ S R
Sbjct: 253 S-VRKLANVHRYTVQCVLMINMFNEKIYLFIWFWFVFVLITTFINTLCTIYRLSFDSSRH 311
Query: 467 KFIKKFLMMHQSYNRSEKQLINSFIREFLRHDGVFLIRMICINAGDIVTADIVNRLWEIY 288
+I+ L + + EK +I SF L+ DGV L+R I +AG +VT +I L++ +
Sbjct: 312 NYIRSLLSGPVNNFKDEKAMIASFANNGLKQDGVLLMRFIDDHAGAMVTKEICEELFKKH 371
Query: 287 KENYKH 270
EN +H
Sbjct: 372 GENLQH 377
>sp|O01634|INX12_CAEEL Innexin-12
Length = 408
Score = 122 bits (305), Expect = 2e-27
Identities = 63/178 (35%), Positives = 104/178 (58%)
Frame = -1
Query: 830 SYILMKFLYGINVIGQLFLMKKFLGFNSSMSSFGYTILSNIADGKEWHQTGIFPRVTYCY 651
SY+ MK L+ INV+ Q L+K+ LG +S +G + S++ G EW +TG FPRVT C
Sbjct: 200 SYLFMKALFLINVLFQFVLLKRMLGVDSYF--WGAEVTSDLWSGNEWPETGNFPRVTMCE 257
Query: 650 IGEIKHLGASNKYVGQCALPINMLNEKIYVFLWFWVFIVGIITAISIPMWFFRIAILSRR 471
E+++L +K+ QC L INM NEKI+V LW+W+ + ++T + WF+R + S
Sbjct: 258 Y-EVRNLDNIHKHSVQCVLMINMFNEKIFVALWWWLCFLTVVTITNTIYWFWRASGTSVS 316
Query: 470 SKFIKKFLMMHQSYNRSEKQLINSFIREFLRHDGVFLIRMICINAGDIVTADIVNRLW 297
FI+ ++ ++ + + F+ EFL D VF++R+I +N G +++ +W
Sbjct: 317 KNFIRPYVEDIDPKVKNNRGKLQQFVSEFLSPDTVFILRLIELNNGKTPVVELIRDMW 374
>sp|Q23027|INX5_CAEEL Innexin-5
Length = 447
Score = 115 bits (289), Expect = 1e-25
Identities = 61/184 (33%), Positives = 104/184 (56%), Gaps = 3/184 (1%)
Frame = -1
Query: 827 YILMKFLYGINVIGQLFLMKKFLGFNSSMSSFGYTILSNIADGKEWHQTGIFPRVTYCYI 648
Y+L+K LY N++ Q +++ FL S M +G+ ++ G+EW TGIFPRVT C
Sbjct: 200 YLLVKILYLANIVLQFWILTYFLETKSWM--WGWQTFQDLMAGREWETTGIFPRVTMCDF 257
Query: 647 GEIKHLGASNKYVGQCALPINMLNEKIYVFLWFWVFIVGIITAISIPMWFFRIAILSRRS 468
I L + + + QC + INML EK+YVF WFW+ VG++T S+ W + S
Sbjct: 258 S-IMDLTSVHDHSIQCVIVINMLAEKVYVFFWFWLLFVGLLTVCSLAYWAVIYMLQSVGR 316
Query: 467 KFIKKFLMMHQSYNRSEKQ---LINSFIREFLRHDGVFLIRMICINAGDIVTADIVNRLW 297
FI +L + +++ + +F+ + L DGVF+ R++ N+GD+ T+ ++ ++
Sbjct: 317 NFIYSYLQQTPEFQTEQERGSFVPANFVDKCLTPDGVFISRLVQQNSGDLFTSIMLGEMF 376
Query: 296 EIYK 285
+Y+
Sbjct: 377 SLYR 380
>sp|Q22549|INX10_CAEEL Innexin-10
Length = 559
Score = 108 bits (271), Expect = 1e-23
Identities = 62/181 (34%), Positives = 97/181 (53%), Gaps = 4/181 (2%)
Frame = -1
Query: 827 YILMKFLYGINVIGQLFLMKKFLGFNSSMSSFGYTILSNIADGKEWHQTGIFPRVTYCYI 648
Y+ KF Y NV QL M +FL +G L ++ +G W Q+G+FPRV+ C
Sbjct: 199 YLCTKFFYLANVCLQLMFMNRFLE-TDKYKWYGMGALVDLLNGTTWEQSGMFPRVSLCDF 257
Query: 647 GEIKHLGASNKYVGQCALPINMLNEKIYVFLWFWVFIVGIITAISIPMWFFRIAILSRRS 468
+++ +G ++ QC L IN+ NEKI++ LWFW + + T S W
Sbjct: 258 -DVRVMGNMQEHTIQCVLVINIFNEKIFILLWFWYLALLVFTFGSFFYWLLVSLWRHLNV 316
Query: 467 KFIKKFLMMHQ-SYNRSE---KQLINSFIREFLRHDGVFLIRMICINAGDIVTADIVNRL 300
+FI + L M +++ SE ++ +N FI +L+ DGVF+IRM+ + +G I D+V L
Sbjct: 317 RFIIRHLEMSDIAFDSSEDGAQEKVNRFISNYLKSDGVFVIRMMTLQSGVIFGTDLVQEL 376
Query: 299 W 297
W
Sbjct: 377 W 377
>sp|O61788|INX17_CAEEL Innexin-17 (Gap junction innexin)
Length = 362
Score = 103 bits (256), Expect = 8e-22
Identities = 59/179 (32%), Positives = 94/179 (52%)
Frame = -1
Query: 815 KFLYGINVIGQLFLMKKFLGFNSSMSSFGYTILSNIADGKEWHQTGIFPRVTYCYIGEIK 636
KFL I + + + F+G +G+TI +I G++W ++G FPRVT+C +++
Sbjct: 188 KFLATILIFISMGFLDYFMGLGPM---YGWTITKDILQGRQWQESGSFPRVTFCDF-QVR 243
Query: 635 HLGASNKYVGQCALPINMLNEKIYVFLWFWVFIVGIITAISIPMWFFRIAILSRRSKFIK 456
LG N + QC L +NM NEK+++ LW+W ++ I++ I FR I + FI
Sbjct: 244 ELGYVNNWSLQCVLMVNMFNEKLFIALWWWYALLAILSIFDIFRVLFRFTI-HHQISFIT 302
Query: 455 KFLMMHQSYNRSEKQLINSFIREFLRHDGVFLIRMICINAGDIVTADIVNRLWEIYKEN 279
+ L S + + F R+ LR DG+ L ++ NA AD V +WE +KEN
Sbjct: 303 RILACTGDSAISATE-VGEFNRKVLRIDGINLTHLVYANATIFEAADFVRPMWEQFKEN 360
>sp|Q27295|EAT5_CAEEL Innexin eat-5
Length = 423
Score = 97.4 bits (241), Expect = 4e-20
Identities = 61/231 (26%), Positives = 104/231 (45%), Gaps = 14/231 (6%)
Frame = -1
Query: 827 YILMKFLYGINVIGQLFLMKKFLGFNSSMSSFGYTILSNIADGKEWHQTGIFPRVTYCYI 648
Y++ K +Y N Q + KFLG N +G IL +I G +W +G FPR+ C
Sbjct: 194 YLVTKLIYMTNSFLQFYSTNKFLGQNDPY--WGMRILDDILKGTDWEHSGNFPRIAMCDF 251
Query: 647 GEIKHLGASNKYVGQCALPINMLNEKIYVFLWFWVFIVGIITAISIPMWFFRIAILSRRS 468
+++ LG +Y QC L +NM NEKI++FL+ W +V +T + + +
Sbjct: 252 -QVRVLGNLQRYSIQCVLTLNMFNEKIFLFLYIWFLLVFFVTLFDSIFLCYNMFSSHKLV 310
Query: 467 KFIKKFLMMHQSYNRSEKQ--------------LINSFIREFLRHDGVFLIRMICINAGD 330
+F+++FL EK+ L++ F D + L++MI + GD
Sbjct: 311 EFLQQFLDNQDQDENDEKKPEERKVYRKEQHSILLSEFCLHKFTPDIIILLKMINNHTGD 370
Query: 329 IVTADIVNRLWEIYKENYKHMDFLNFSAYPKSMDVTTGLRRNQNISSSDES 177
IV +IV R+W + E + F M+ + +++ + S
Sbjct: 371 IVCTEIVGRMWNEFLERDAKLVLQRFVDNDHHMETKSSSLKSEKLFEEQRS 421
>sp|Q21123|INX7_CAEEL Innexin-7
Length = 556
Score = 93.2 bits (230), Expect = 8e-19
Identities = 56/191 (29%), Positives = 101/191 (52%), Gaps = 9/191 (4%)
Frame = -1
Query: 827 YILMKFLYGINVIGQLFLMKKFLGFNSSMSSFGY----TILSNIADGKE-WHQTGIFPRV 663
Y + K + +NVI Q L+ K++ + +FG+ TI +G E W + G+FPRV
Sbjct: 220 YFVAKVAFLLNVILQSKLLNKYMLPHDRQQNFGFDMWKTIFYGSTNGNETWRENGVFPRV 279
Query: 662 TYCYIGEIKHLGASNKYVGQCALPINMLNEKIYVFLWFWVFIVGIITAISIPMWFFRIAI 483
T C E + +G + QC L +N+ EKI+VFLW W ++ T ++ W F +
Sbjct: 280 TLCDF-ETRDMGNVQMHTVQCVLLLNLFTEKIFVFLWAWYILLTAFTVGNLFSWLFAVFN 338
Query: 482 LSRRSKFIKKFLMMHQS-YNRSE---KQLINSFIREFLRHDGVFLIRMICINAGDIVTAD 315
+ FI L M ++ +++ + ++ + FI +L DG+FL+++I +A + T +
Sbjct: 339 ETYNEHFILNHLEMCETPFDKDDLKNREHVTRFITLYLGTDGLFLLQLIAQHADVVFTTE 398
Query: 314 IVNRLWEIYKE 282
++ L++ Y E
Sbjct: 399 LIAALFKTYIE 409
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,157,410
Number of Sequences: 369166
Number of extensions: 1988158
Number of successful extensions: 4451
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4284
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4416
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8052550455
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)