Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_003_N08 (351 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9GKQ8|DSG1_CANFA Desmoglein-1 precursor (Desmosomal gly... 30 2.2 sp|Q12816|TROP_HUMAN Trophinin (MAGE-D3 antigen) 29 3.8 sp|Q8Z3Z9|KDUI_SALTI 4-deoxy-L-threo-5-hexosulose-uronate k... 28 5.0 sp|P46842|APA_MYCLE Alanine and proline-rich secreted prote... 28 5.0 sp|O76819|HMDH_AGRIP 3-hydroxy-3-methylglutaryl-coenzyme A ... 28 5.0 sp|Q8ZM98|KDUI_SALTY 4-deoxy-L-threo-5-hexosulose-uronate k... 28 5.0 sp|P36269|GGT5_HUMAN Gamma-glutamyltransferase 5 precursor ... 28 6.5 sp|P37232|PPARA_XENLA Peroxisome proliferator-activated rec... 28 6.5 sp|P0A554|DXS_MYCTU 1-deoxy-D-xylulose-5-phosphate synthase... 28 8.5 sp|Q6NRG6|SAS6_XENLA Spindle assembly abnormal protein 6 ho... 28 8.5
>sp|Q9GKQ8|DSG1_CANFA Desmoglein-1 precursor (Desmosomal glycoprotein 1) (DG1) (DGI) Length = 1054 Score = 29.6 bits (65), Expect = 2.2 Identities = 23/75 (30%), Positives = 32/75 (42%) Frame = +3 Query: 30 VESIGDITDISQEIGDLGTVLDGASRILSLVGGRGVGLAPAEHGHASHSDASFDPKFAQK 209 V S I+ IS +G V G + SL GG G+ + H +S D F+Q Sbjct: 972 VVSGSGISGISGLVGSAMGVSGGGMAMNSLGGGGGLSSSMGGTATIGHVRSSSDHHFSQT 1031 Query: 210 VGFGPNSHARSNFAE 254 +G S ARS + Sbjct: 1032 LGSASPSTARSRITK 1046
>sp|Q12816|TROP_HUMAN Trophinin (MAGE-D3 antigen) Length = 1387 Score = 28.9 bits (63), Expect = 3.8 Identities = 20/59 (33%), Positives = 30/59 (50%) Frame = +3 Query: 72 GDLGTVLDGASRILSLVGGRGVGLAPAEHGHASHSDASFDPKFAQKVGFGPNSHARSNF 248 G LGT S + + G G GL+ ++ G S +ASFD + +GFG S+ + F Sbjct: 1247 GGLGTNASFGSTLGTSAGFSG-GLSTSD-GFGSRPNASFDRGLSTIIGFGSGSNTSTGF 1303
>sp|Q8Z3Z9|KDUI_SALTI 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase (5-keto-4-deoxyuronate isomerase) (DKI isomerase) Length = 278 Score = 28.5 bits (62), Expect = 5.0 Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 21/114 (18%) Frame = +3 Query: 3 IFLVSQFLFVES------IGDITDISQEI---GDLGTVLDGASRILSL-------VGGRG 134 IF+ ++ V S +G I +S + G++G L G SR+L +GG G Sbjct: 29 IFVADEYTMVYSHIDRIIVGGIMPVSHPVEIGGEVGKQL-GVSRLLDRRELGVINIGGAG 87 Query: 135 VGLAPAEHGHASHSDASFDPKFAQKVGFGPNSHARS-----NFAEVQRGHATRK 281 + + H DA + K A+++ F N +R N A + T+K Sbjct: 88 AIIVDGQRHDIGHRDALYIGKGAKELVFVSNEASRPAKFYYNCAPAHTAYPTKK 141
>sp|P46842|APA_MYCLE Alanine and proline-rich secreted protein apa precursor (Antigen 43L) (Fibronectin attachment protein) (FAP-L) Length = 287 Score = 28.5 bits (62), Expect = 5.0 Identities = 12/36 (33%), Positives = 22/36 (61%), Gaps = 4/36 (11%) Frame = -3 Query: 160 PCSAGANPTPLPPTSDKILDAPSRTV----PKSPIS 65 P +A A+P PLPP++ +P++ + P +P+S Sbjct: 34 PAAANADPAPLPPSTATAAPSPAQEIITPLPGAPVS 69
>sp|O76819|HMDH_AGRIP 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) Length = 833 Score = 28.5 bits (62), Expect = 5.0 Identities = 14/35 (40%), Positives = 21/35 (60%), Gaps = 2/35 (5%) Frame = +3 Query: 60 SQEIGDLG--TVLDGASRILSLVGGRGVGLAPAEH 158 S E+G +G T+L G L ++G +G G PAE+ Sbjct: 743 SLEVGTVGGGTILTGQGACLDILGVKGAGARPAEN 777
>sp|Q8ZM98|KDUI_SALTY 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase (5-keto-4-deoxyuronate isomerase) (DKI isomerase) Length = 278 Score = 28.5 bits (62), Expect = 5.0 Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 21/114 (18%) Frame = +3 Query: 3 IFLVSQFLFVES------IGDITDISQEI---GDLGTVLDGASRILSL-------VGGRG 134 IF+ ++ V S +G I +S + G++G L G SR+L +GG G Sbjct: 29 IFVADEYTMVYSHIDRIIVGGIMPVSHPVEIGGEVGKQL-GVSRLLDRRELGVINIGGAG 87 Query: 135 VGLAPAEHGHASHSDASFDPKFAQKVGFGPNSHARS-----NFAEVQRGHATRK 281 + + H DA + K A+++ F N +R N A + T+K Sbjct: 88 AIIVDGQRHDIGHRDALYIGKGAKELVFVSNEASRPAKFYYNCAPAHTAYPTKK 141
>sp|P36269|GGT5_HUMAN Gamma-glutamyltransferase 5 precursor (Gamma-glutamyltranspeptidase 5) (Gamma-glutamyltransferase-like activity 1) (GGT-rel) [Contains: Gamma-glutamyltransferase 5 heavy chain; Gamma-glutamyltransferase 5 light chain] Length = 586 Score = 28.1 bits (61), Expect = 6.5 Identities = 15/45 (33%), Positives = 21/45 (46%) Frame = -3 Query: 157 CSAGANPTPLPPTSDKILDAPSRTVPKSPIS*LISVMSPMLSTNR 23 C G+ TP P + D++ AP R P P S M P + N+ Sbjct: 435 CPWGSGTTPSPVSGDRVGGAPGRCWPPVPGERSPSSMVPSILINK 479
>sp|P37232|PPARA_XENLA Peroxisome proliferator-activated receptor alpha (PPAR-alpha) Length = 474 Score = 28.1 bits (61), Expect = 6.5 Identities = 14/26 (53%), Positives = 18/26 (69%) Frame = +3 Query: 27 FVESIGDITDISQEIGDLGTVLDGAS 104 F++ I DI DI+Q IGD G+ GAS Sbjct: 31 FLQDIVDIQDITQTIGDDGSTPFGAS 56
>sp|P0A554|DXS_MYCTU 1-deoxy-D-xylulose-5-phosphate synthase (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS) sp|P0A555|DXS_MYCBO 1-deoxy-D-xylulose-5-phosphate synthase (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS) Length = 638 Score = 27.7 bits (60), Expect = 8.5 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Frame = +3 Query: 96 GASRILSLVGGRGVGLAPAEHGHAS--HSDASFDPKFAQ--KVGFGPNSHARSNFAEVQR 263 GA I+ +V +G+G PAE A HS DP Q KV GP A F++ Sbjct: 269 GAPVIVHVVTRKGMGYPPAEADQAEQMHSTVPIDPATGQATKVA-GPGWTA--TFSDALI 325 Query: 264 GHATRKR 284 G+A ++R Sbjct: 326 GYAQKRR 332
>sp|Q6NRG6|SAS6_XENLA Spindle assembly abnormal protein 6 homolog Length = 668 Score = 27.7 bits (60), Expect = 8.5 Identities = 17/45 (37%), Positives = 21/45 (46%) Frame = -3 Query: 226 LGPNPTF*ANLGSNEASE*LA*PCSAGANPTPLPPTSDKILDAPS 92 L P F AN+ N++ L CS P P P TS IL + S Sbjct: 567 LNPQAAFKANVRFNQSPTAL---CSPAVEPRPAPSTSTPILPSTS 608
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 35,500,412 Number of Sequences: 369166 Number of extensions: 635171 Number of successful extensions: 2212 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2135 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2212 length of database: 68,354,980 effective HSP length: 84 effective length of database: 52,837,240 effective search space used: 1690791680 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)