Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_N06
(784 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P05166|PCCB_HUMAN Propionyl-CoA carboxylase beta chain, ... 389 e-108
sp|P79384|PCCB_PIG Propionyl-CoA carboxylase beta chain, mi... 388 e-108
sp|P07633|PCCB_RAT Propionyl-CoA carboxylase beta chain, mi... 384 e-106
sp|Q99MN9|PCCB_MOUSE Propionyl-CoA carboxylase beta chain, ... 383 e-106
sp|P53003|PCCB_SACER Propionyl-CoA carboxylase beta chain (... 271 1e-72
sp|P96885|PCC5_MYCTU Probable propionyl-CoA carboxylase bet... 264 2e-70
sp|P53002|PCCB_MYCLE Probable propionyl-CoA carboxylase bet... 263 5e-70
sp|P54541|PCCB_BACSU Putative propionyl-CoA carboxylase bet... 253 3e-67
sp|Q8GBW6|12S_PROFR Methylmalonyl-CoA carboxyltransferase 1... 252 7e-67
sp|P63408|PCC6_MYCBO Probable propionyl-CoA carboxylase bet... 189 7e-48
>sp|P05166|PCCB_HUMAN Propionyl-CoA carboxylase beta chain, mitochondrial precursor (PCCase
beta subunit) (Propanoyl-CoA:carbon dioxide ligase beta
subunit)
Length = 539
Score = 389 bits (1000), Expect = e-108
Identities = 185/233 (79%), Positives = 211/233 (90%)
Frame = +2
Query: 2 LESTAAYNMLDVIYGVVDESEFFEIMPTYAKNIIIGFGRMHGRTVGIIGNQPKVAAGCLD 181
LEST AYNM+D+I+ VVDE EFFEIMP YAKNII+GF RM+GRTVGI+GNQPKVA+GCLD
Sbjct: 308 LESTKAYNMVDIIHSVVDEREFFEIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLD 367
Query: 182 INASVKGARFVRFCDAFNIPLLTFVDVPGFLPGTVQEYGGIIRHGAKLLYAYAEATVPKI 361
IN+SVKGARFVRFCDAFNIPL+TFVDVPGFLPGT QEYGGIIRHGAKLLYA+AEATVPK+
Sbjct: 368 INSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKV 427
Query: 362 TIITRKAYGGAYDVMSSKHLRGDINYAWPTAEVAVMGAKGAVQIIFRGSGSEQLTKEAEY 541
T+ITRKAYGGAYDVMSSKHL GD NYAWPTAE+AVMGAKGAV+IIF+G + + +AEY
Sbjct: 428 TVITRKAYGGAYDVMSSKHLCGDTNYAWPTAEIAVMGAKGAVEIIFKGHENVE-AAQAEY 486
Query: 542 VDKFANPFPAAVRGFVDDIIEPRRTRAKICQDLDLLQHKQLINPWKKHGNIPL 700
++KFANPFPAAVRGFVDDII+P TRA+IC DLD+L K++ PW+KH NIPL
Sbjct: 487 IEKFANPFPAAVRGFVDDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL 539
>sp|P79384|PCCB_PIG Propionyl-CoA carboxylase beta chain, mitochondrial precursor (PCCase
beta subunit) (Propanoyl-CoA:carbon dioxide ligase beta
subunit)
Length = 539
Score = 388 bits (997), Expect = e-108
Identities = 184/233 (78%), Positives = 211/233 (90%)
Frame = +2
Query: 2 LESTAAYNMLDVIYGVVDESEFFEIMPTYAKNIIIGFGRMHGRTVGIIGNQPKVAAGCLD 181
LEST AY+M+D+IY +VDE +FFEIMP YAKNII+GF RM+GRTVGI+GNQPKVA+GCLD
Sbjct: 308 LESTRAYDMVDIIYSIVDERDFFEIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLD 367
Query: 182 INASVKGARFVRFCDAFNIPLLTFVDVPGFLPGTVQEYGGIIRHGAKLLYAYAEATVPKI 361
IN+SVKGARFVRFCDAFNIPL+TFVDVPGFLPGT QEYGGIIRHGAKLLYA+AEATVPKI
Sbjct: 368 INSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKI 427
Query: 362 TIITRKAYGGAYDVMSSKHLRGDINYAWPTAEVAVMGAKGAVQIIFRGSGSEQLTKEAEY 541
T+ITRKAYGGAYDVMSSKHL GD NYAWPTAE+AVMGAKGAV+IIF+G + + +AEY
Sbjct: 428 TVITRKAYGGAYDVMSSKHLCGDTNYAWPTAEIAVMGAKGAVEIIFKGHENVE-AAQAEY 486
Query: 542 VDKFANPFPAAVRGFVDDIIEPRRTRAKICQDLDLLQHKQLINPWKKHGNIPL 700
++KFANPFPAAVRGFVDDII+P TRA+IC DLD+L K++ PW+KH NIPL
Sbjct: 487 IEKFANPFPAAVRGFVDDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL 539
>sp|P07633|PCCB_RAT Propionyl-CoA carboxylase beta chain, mitochondrial precursor (PCCase
beta subunit) (Propanoyl-CoA:carbon dioxide ligase beta
subunit)
Length = 541
Score = 384 bits (985), Expect = e-106
Identities = 182/233 (78%), Positives = 209/233 (89%)
Frame = +2
Query: 2 LESTAAYNMLDVIYGVVDESEFFEIMPTYAKNIIIGFGRMHGRTVGIIGNQPKVAAGCLD 181
LES+ AYNMLD+I+ V+DE EFFEIMP YAKNI+IGF RM+GRTVGI+GNQP VA+GCLD
Sbjct: 310 LESSKAYNMLDIIHAVIDEREFFEIMPNYAKNIVIGFARMNGRTVGIVGNQPNVASGCLD 369
Query: 182 INASVKGARFVRFCDAFNIPLLTFVDVPGFLPGTVQEYGGIIRHGAKLLYAYAEATVPKI 361
IN+SVKGARFVRFCDAF+IPL+TFVDVPGFLPGT QEYGGIIRHGAKLLYA+AEATVPKI
Sbjct: 370 INSSVKGARFVRFCDAFSIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKI 429
Query: 362 TIITRKAYGGAYDVMSSKHLRGDINYAWPTAEVAVMGAKGAVQIIFRGSGSEQLTKEAEY 541
T+ITRKAYGGAYDVMSSKHL GD NYAWPTAE+AVMGAKGAV+IIF+G + +AEY
Sbjct: 430 TVITRKAYGGAYDVMSSKHLLGDTNYAWPTAEIAVMGAKGAVEIIFKGHEDVE-AAQAEY 488
Query: 542 VDKFANPFPAAVRGFVDDIIEPRRTRAKICQDLDLLQHKQLINPWKKHGNIPL 700
V+KFANPFPAAVRGFVDDII+P TRA+IC DL++L K++ PW+KH N+PL
Sbjct: 489 VEKFANPFPAAVRGFVDDIIQPSSTRARICCDLEVLASKKVHRPWRKHANVPL 541
>sp|Q99MN9|PCCB_MOUSE Propionyl-CoA carboxylase beta chain, mitochondrial precursor (PCCase
beta subunit) (Propanoyl-CoA:carbon dioxide ligase beta
subunit)
Length = 541
Score = 383 bits (984), Expect = e-106
Identities = 182/233 (78%), Positives = 209/233 (89%)
Frame = +2
Query: 2 LESTAAYNMLDVIYGVVDESEFFEIMPTYAKNIIIGFGRMHGRTVGIIGNQPKVAAGCLD 181
LES+ AYNMLD+I+ V+DE EFFEIMP+YA NI++GF RM+GRTVGI+GNQP VA+GCLD
Sbjct: 310 LESSKAYNMLDIIHAVIDEREFFEIMPSYALNIVVGFARMNGRTVGIVGNQPNVASGCLD 369
Query: 182 INASVKGARFVRFCDAFNIPLLTFVDVPGFLPGTVQEYGGIIRHGAKLLYAYAEATVPKI 361
IN+SVKGARFVRFCDAFNIPL+TFVDVPGFLPGT QEYGGIIRHGAKLLYA+AEATVPKI
Sbjct: 370 INSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKI 429
Query: 362 TIITRKAYGGAYDVMSSKHLRGDINYAWPTAEVAVMGAKGAVQIIFRGSGSEQLTKEAEY 541
T+ITRKAYGGAYDVMSSKHL GD NYAWPTAE+AVMGAKGAV+IIF+G + +AEY
Sbjct: 430 TVITRKAYGGAYDVMSSKHLLGDTNYAWPTAEIAVMGAKGAVEIIFKGHQDVE-AAQAEY 488
Query: 542 VDKFANPFPAAVRGFVDDIIEPRRTRAKICQDLDLLQHKQLINPWKKHGNIPL 700
V+KFANPFPAAVRGFVDDII+P TRA+IC DL++L K++ PW+KH NIPL
Sbjct: 489 VEKFANPFPAAVRGFVDDIIQPSSTRARICCDLEVLASKKVHRPWRKHANIPL 541
>sp|P53003|PCCB_SACER Propionyl-CoA carboxylase beta chain (PCCase) (Propanoyl-CoA:carbon
dioxide ligase)
Length = 546
Score = 271 bits (693), Expect = 1e-72
Identities = 136/238 (57%), Positives = 168/238 (70%), Gaps = 11/238 (4%)
Frame = +2
Query: 20 YNMLDVIYGVVDESEFFEIMPTYAKNIIIGFGRMHGRTVGIIGNQPKVAAGCLDINASVK 199
Y+M +VI +VDE EF E+ +A N++ GFGR+ G +VG++ NQP AG LDI+AS K
Sbjct: 309 YDMREVITRLVDEGEFLEVSALFAPNMLCGFGRIEGASVGVVANQPMQLAGTLDIDASEK 368
Query: 200 GARFVRFCDAFNIPLLTFVDVPGFLPGTVQEYGGIIRHGAKLLYAYAEATVPKITIITRK 379
ARFVRFCDAFNIP+LT VDVPGFLPGT Q++ IIR GAKLLYAYAEATVP +T+ITRK
Sbjct: 369 AARFVRFCDAFNIPVLTLVDVPGFLPGTGQDWNAIIRRGAKLLYAYAEATVPLVTVITRK 428
Query: 380 AYGGAYDVMSSKHLRGDINYAWPTAEVAVMGAKGAVQIIFRGSGSEQLTK---------- 529
AYGGAYDVM SKHL DIN AWPTA++AVMGA+GA I++R +E +
Sbjct: 429 AYGGAYDVMGSKHLGADINLAWPTAQIAVMGAQGAANILYRRQLAEAAERGEDVEALRAR 488
Query: 530 -EAEYVDKFANPFPAAVRGFVDDIIEPRRTRAKICQDLDLLQHKQLINPWKKHGNIPL 700
+ EY D NP+ AA RG+VD +I P TR + + L +L K+ P KKHGNIPL
Sbjct: 489 LQQEYEDTLCNPYVAAERGYVDSVIPPSHTRGHVARALRMLADKREALPAKKHGNIPL 546
>sp|P96885|PCC5_MYCTU Probable propionyl-CoA carboxylase beta chain 5 (PCCase)
(Propanoyl-CoA:carbon dioxide ligase)
Length = 548
Score = 264 bits (674), Expect = 2e-70
Identities = 139/238 (58%), Positives = 166/238 (69%), Gaps = 11/238 (4%)
Frame = +2
Query: 20 YNMLDVIYGVVDESEFFEIMPTYAKNIIIGFGRMHGRTVGIIGNQPKVAAGCLDINASVK 199
Y+M +VI ++D+ EF EI YA+NI++GFGR+ GR VGI+ NQP AGCLDINAS K
Sbjct: 312 YDMHEVITRLLDD-EFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEK 370
Query: 200 GARFVRFCDAFNIPLLTFVDVPGFLPGTVQEYGGIIRHGAKLLYAYAEATVPKITIITRK 379
ARFVR CD FNIP++ VDVPGFLPGT QEY GIIR GAKLLYAY EATVPKIT+ITRK
Sbjct: 371 AARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRK 430
Query: 380 AYGGAYDVMSSKHLRGDINYAWPTAEVAVMGAKGAVQIIFRGSGSE-----------QLT 526
AYGGAY VM SK + D+N AWPTA++AVMGA GAV ++R +E +L
Sbjct: 431 AYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLR 490
Query: 527 KEAEYVDKFANPFPAAVRGFVDDIIEPRRTRAKICQDLDLLQHKQLINPWKKHGNIPL 700
+ EY D NP+ AA RG+VD +I P TR I L LL+ K P KKHGN+PL
Sbjct: 491 LQQEYEDTLVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL 548
>sp|P53002|PCCB_MYCLE Probable propionyl-CoA carboxylase beta chain 5 (PCCase)
(Propanoyl-CoA:carbon dioxide ligase)
Length = 549
Score = 263 bits (671), Expect = 5e-70
Identities = 135/238 (56%), Positives = 164/238 (68%), Gaps = 11/238 (4%)
Frame = +2
Query: 20 YNMLDVIYGVVDESEFFEIMPTYAKNIIIGFGRMHGRTVGIIGNQPKVAAGCLDINASVK 199
Y+M +V+ ++DE EF E+ YA NI++G GR+ R VGI+ NQP AGCLDINAS K
Sbjct: 312 YDMHEVVTRLLDEEEFLEVQAGYATNIVVGLGRIDDRPVGIVANQPIQFAGCLDINASEK 371
Query: 200 GARFVRFCDAFNIPLLTFVDVPGFLPGTVQEYGGIIRHGAKLLYAYAEATVPKITIITRK 379
ARFVR CD FNIP++ VDVPGFLPGT QEY GIIR GAKLL+AY EATVPKIT+ITRK
Sbjct: 372 AARFVRVCDCFNIPIVMLVDVPGFLPGTEQEYDGIIRRGAKLLFAYGEATVPKITVITRK 431
Query: 380 AYGGAYDVMSSKHLRGDINYAWPTAEVAVMGAKGAVQIIFRGSGSE-----------QLT 526
AYGGAY VM SK++ D+N AWPTA++AVMGA GAV ++R ++ +L
Sbjct: 432 AYGGAYCVMGSKNMGCDVNLAWPTAQIAVMGASGAVGFVYRKELAQAAKNGANVDELRLQ 491
Query: 527 KEAEYVDKFANPFPAAVRGFVDDIIEPRRTRAKICQDLDLLQHKQLINPWKKHGNIPL 700
+ EY D NP+ AA RG+VD +I P TR I L LL+ K P KKHGNIPL
Sbjct: 492 LQQEYEDTLVNPYIAAERGYVDAVIPPSHTRGYIATALHLLERKIAHLPPKKHGNIPL 549
>sp|P54541|PCCB_BACSU Putative propionyl-CoA carboxylase beta chain (PCCase)
(Propanoyl-CoA:carbon dioxide ligase)
Length = 506
Score = 253 bits (647), Expect = 3e-67
Identities = 130/239 (54%), Positives = 165/239 (69%), Gaps = 7/239 (2%)
Frame = +2
Query: 5 ESTAAYNMLDVIYGVVDESEFFEIMPTYAKNIIIGFGRMHGRTVGIIGNQPKVAAGCLDI 184
++T Y++ VI + D FFEI P +AKNI+IGF R+ + +GI+ +QPK AG L I
Sbjct: 268 DTTKPYDVRKVIRELADPQSFFEIQPFFAKNIVIGFARLGEKAIGIVASQPKHLAGSLTI 327
Query: 185 NASVKGARFVRFCDAFNIPLLTFVDVPGFLPGTVQEYGGIIRHGAKLLYAYAEATVPKIT 364
+A+ K ARF+RFCDAF+IPLLT DVPGFLPG QE+ GIIRHGAKLL+AYAEATVPK+T
Sbjct: 328 DAADKAARFIRFCDAFDIPLLTVEDVPGFLPGIQQEHNGIIRHGAKLLFAYAEATVPKVT 387
Query: 365 IITRKAYGGAYDVMSSKHLRGDINYAWPTAEVAVMGAKGAVQIIF----RGSGSEQLTKE 532
+I RKAYGGAY M+SK + D+ +AWP AE+AVMG +GA I++ + S Q TK
Sbjct: 388 LIIRKAYGGAYVAMNSKAIGADLVFAWPNAEIAVMGPEGAASILYEKEIKASADPQKTKR 447
Query: 533 ---AEYVDKFANPFPAAVRGFVDDIIEPRRTRAKICQDLDLLQHKQLINPWKKHGNIPL 700
AEY + A P+ AA G VDDII P +R ++ Q +L HK P KKHGNIPL
Sbjct: 448 EKTAEYKKQNAGPYKAAACGMVDDIILPEESRGRLIQAFHMLTHKTEERPKKKHGNIPL 506
>sp|Q8GBW6|12S_PROFR Methylmalonyl-CoA carboxyltransferase 12S subunit (Transcarboxylase
12S subunit)
Length = 611
Score = 252 bits (644), Expect = 7e-67
Identities = 125/240 (52%), Positives = 163/240 (67%), Gaps = 7/240 (2%)
Frame = +2
Query: 2 LESTAAYNMLDVIYGVVDESEFFEIMPTYAKNIIIGFGRMHGRTVGIIGNQPKVAAGCLD 181
++ Y++ DVI +VD ++ E+ YA N++ F R++GR+VGI+ NQP V +GCLD
Sbjct: 285 IDGKKGYDVRDVIAKIVDWGDYLEVKAGYATNLVTAFARVNGRSVGIVANQPSVMSGCLD 344
Query: 182 INASVKGARFVRFCDAFNIPLLTFVDVPGFLPGTVQEYGGIIRHGAKLLYAYAEATVPKI 361
INAS K A FV FCD+FNIPL+ VDVPGFLPG QEYGGIIRHGAK+LYAY+EATVPKI
Sbjct: 345 INASDKAAEFVNFCDSFNIPLVQLVDVPGFLPGVQQEYGGIIRHGAKMLYAYSEATVPKI 404
Query: 362 TIITRKAYGGAYDVMSSKHLRGDINYAWPTAEVAVMGAKGAVQIIFR-------GSGSEQ 520
T++ RKAYGG+Y M ++ L D YAWP+AE+AVMGA+GA +IFR + +
Sbjct: 405 TVVLRKAYGGSYLAMCNRDLGADAVYAWPSAEIAVMGAEGAANVIFRKEIKAADDPDAMR 464
Query: 521 LTKEAEYVDKFANPFPAAVRGFVDDIIEPRRTRAKICQDLDLLQHKQLINPWKKHGNIPL 700
K EY + F P+ AA RG VDD+I+P TR KI L++ K+ P KK +PL
Sbjct: 465 AEKIEEYQNAFNTPYVAAARGQVDDVIDPADTRRKIASALEMYATKRQTRPAKKPWKLPL 524
>sp|P63408|PCC6_MYCBO Probable propionyl-CoA carboxylase beta chain 6 (PCCase)
(Propanoyl-CoA:carbon dioxide ligase)
sp|P63407|PCC6_MYCTU Probable propionyl-CoA carboxylase beta chain 6 (PCCase)
(Propanoyl-CoA:carbon dioxide ligase)
Length = 473
Score = 189 bits (480), Expect = 7e-48
Identities = 101/241 (41%), Positives = 150/241 (62%), Gaps = 10/241 (4%)
Frame = +2
Query: 8 STAAYNMLDVIYGVVD-ESEFFEIMPTYAKNIIIGFGRMHGRTVGIIGNQPKVAAGCLDI 184
S AY++ ++ ++D ++ F E +A ++++G GR+ GRTVG++ N P GCL+
Sbjct: 238 SRRAYDVRPIVTAILDADTPFDEFQANWAPSMVVGLGRLSGRTVGVLANNPLRLGGCLNS 297
Query: 185 NASVKGARFVRFCDAFNIPLLTFVDVPGFLPGTVQEYGGIIRHGAKLLYAYAEATVPKIT 364
++ K ARFVR CDAF IPL+ VDVPG+LPG QE+GG++R GAKLL+A+ E TVP++T
Sbjct: 298 ESAEKAARFVRLCDAFGIPLVVVVDVPGYLPGVDQEWGGVVRRGAKLLHAFGECTVPRVT 357
Query: 365 IITRKAYGGAYDVMSSKHLRGDINYAWPTAEVAVMGAKGAVQIIFRGSGSEQLTKEAEYV 544
++TRK YGGAY M+S+ L +AWP AEVAVMGAK AV I+ + + E E +
Sbjct: 358 LVTRKTYGGAYIAMNSRSLNATKVFAWPDAEVAVMGAKAAVGILHKKKLAAAPEHEREAL 417
Query: 545 --------DKFANPFPAAVR-GFVDDIIEPRRTRAKICQDLDLLQHKQLINPWKKHGNIP 697
++ A +A+ G VD+ I+P TR+K+ + L ++ +H NIP
Sbjct: 418 HDQLAAEHERIAGGVDSALDIGVVDEKIDPAHTRSKLTEALAQAPARR-----GRHKNIP 472
Query: 698 L 700
L
Sbjct: 473 L 473
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,982,758
Number of Sequences: 369166
Number of extensions: 2082672
Number of successful extensions: 5762
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5519
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5741
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7357347200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)