Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_M07
(838 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UHB6|EPLIN_HUMAN Epithelial protein lost in neoplasm 86 1e-16
sp|Q9ERG0|EPLIN_MOUSE Epithelial protein lost in neoplasm (... 86 1e-16
sp|P29675|SF3_HELAN Pollen-specific protein SF3 69 2e-11
sp|Q14847|LASP1_HUMAN LIM and SH3 domain protein 1 (LASP-1)... 63 9e-10
sp|Q99MZ8|LASP1_RAT LIM and SH3 domain protein 1 (LASP-1) 63 9e-10
sp|Q61792|LASP1_MOUSE LIM and SH3 domain protein 1 (LASP-1)... 63 1e-09
sp|O94851|MICA2_HUMAN Protein MICAL-2 62 2e-09
sp|P36201|CRIP2_RAT Cysteine-rich protein 2 (CRP2) (Protein... 62 2e-09
sp|Q9DCT8|CRIP2_MOUSE Cysteine-rich protein 2 (CRP2) (Heart... 62 2e-09
sp|P34416|LASP1_CAEEL LIM and SH3 domain protein F42H10.3 62 3e-09
>sp|Q9UHB6|EPLIN_HUMAN Epithelial protein lost in neoplasm
Length = 759
Score = 86.3 bits (212), Expect = 1e-16
Identities = 34/65 (52%), Positives = 45/65 (69%)
Frame = +3
Query: 570 CCICNKKVYPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHYVELFKKR 749
C C K VYPME+L N ++FH +CFRC+ C N LS G ++ HG+ YC PH+ +LFK +
Sbjct: 390 CVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFKSK 449
Query: 750 GRYDE 764
G YDE
Sbjct: 450 GNYDE 454
>sp|Q9ERG0|EPLIN_MOUSE Epithelial protein lost in neoplasm (mEPLIN)
Length = 753
Score = 86.3 bits (212), Expect = 1e-16
Identities = 34/65 (52%), Positives = 45/65 (69%)
Frame = +3
Query: 570 CCICNKKVYPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHYVELFKKR 749
C C K VYPME+L N ++FH +CFRC+ C N LS G ++ HG+ YC PH+ +LFK +
Sbjct: 388 CVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFKSK 447
Query: 750 GRYDE 764
G YDE
Sbjct: 448 GNYDE 452
>sp|P29675|SF3_HELAN Pollen-specific protein SF3
Length = 219
Score = 68.6 bits (166), Expect = 2e-11
Identities = 28/72 (38%), Positives = 41/72 (56%)
Frame = +3
Query: 558 TNGDCCICNKKVYPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHYVEL 737
T C +C K VY ++KL N +++HK CFRC C + L NF+ G YC H+ +L
Sbjct: 7 TTQKCTVCEKTVYLVDKLVANQRVYHKACFRCHHCNSTLKLSNFNSFDGVVYCRHHFDQL 66
Query: 738 FKKRGRYDEIDD 773
FK+ G ++ D
Sbjct: 67 FKRTGSLEKSFD 78
Score = 64.7 bits (156), Expect = 3e-10
Identities = 24/71 (33%), Positives = 42/71 (59%)
Frame = +3
Query: 558 TNGDCCICNKKVYPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHYVEL 737
T C C K VYP+E++ + +H+ CF+C +S N+ + G+ YC H+++L
Sbjct: 106 TRDKCNACAKIVYPIERVKVDGTAYHRACFKCCHGGCTISPSNYIAHEGRLYCKHHHIQL 165
Query: 738 FKKRGRYDEID 770
FKK+G Y +++
Sbjct: 166 FKKKGNYSQLE 176
>sp|Q14847|LASP1_HUMAN LIM and SH3 domain protein 1 (LASP-1) (MLN 50)
Length = 261
Score = 63.2 bits (152), Expect = 9e-10
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +3
Query: 561 NGDCCICNKKVYPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHY 728
N +C C K VYP EK++ DK +HK CF C CK L+ N+ KPYC HY
Sbjct: 2 NPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHY 57
>sp|Q99MZ8|LASP1_RAT LIM and SH3 domain protein 1 (LASP-1)
Length = 263
Score = 63.2 bits (152), Expect = 9e-10
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +3
Query: 561 NGDCCICNKKVYPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHY 728
N +C C K VYP EK++ DK +HK CF C CK L+ N+ KPYC HY
Sbjct: 2 NPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHY 57
>sp|Q61792|LASP1_MOUSE LIM and SH3 domain protein 1 (LASP-1) (MLN 50)
Length = 263
Score = 62.8 bits (151), Expect = 1e-09
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +3
Query: 561 NGDCCICNKKVYPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHY 728
N +C C K VYP EK++ DK +HK CF C CK L+ N+ KPYC HY
Sbjct: 2 NPNCARCGKIVYPTEKVNCLDKYWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHY 57
>sp|O94851|MICA2_HUMAN Protein MICAL-2
Length = 1124
Score = 62.4 bits (150), Expect = 2e-09
Identities = 33/85 (38%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Frame = +3
Query: 552 NLTNGDCC-ICNKKVYPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSF--NHGKPYCTP 722
NL D C C K+VY ME+LS FH+ CFRC+ C L ++F + GK YC P
Sbjct: 995 NLGGSDTCYFCKKRVYVMERLSAEGHFFHRECFRCSICATTLRLAAYTFDCDEGKFYCKP 1054
Query: 723 HYVEL---FKKRGRYDEIDDNIENE 788
H++ K+R R E+ E E
Sbjct: 1055 HFIHCKTNSKQRKRRAELKQQREEE 1079
>sp|P36201|CRIP2_RAT Cysteine-rich protein 2 (CRP2) (Protein ESP1)
Length = 208
Score = 62.0 bits (149), Expect = 2e-09
Identities = 33/93 (35%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Frame = +3
Query: 477 KQKVTYSPTKGKDVKSLSSTYGHEGNLTNGDCCICNKKVYPMEKLSTNDKIFHKTCFRCT 656
+++ T P KG S +T+ E N+ C CNK+VY EK+++ K +H+ C RC
Sbjct: 99 EERKTSGPPKGPSKASSVTTFTGEPNM----CPRCNKRVYFAEKVTSLGKDWHRPCLRCE 154
Query: 657 KCKNALSTGNFSFNHGKPYC-TPHYVELFKKRG 752
+C L+ G + + G+PYC P Y LF +G
Sbjct: 155 RCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKG 187
Score = 53.9 bits (128), Expect = 5e-07
Identities = 25/62 (40%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Frame = +3
Query: 570 CCICNKKVYPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYC-TPHYVELFKK 746
C C+K VY EK+S+ K +HK C +C +C L+ G + + GKP+C P Y LF
Sbjct: 5 CPKCDKTVYFAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGP 64
Query: 747 RG 752
+G
Sbjct: 65 KG 66
>sp|Q9DCT8|CRIP2_MOUSE Cysteine-rich protein 2 (CRP2) (Heart LIM protein)
Length = 208
Score = 62.0 bits (149), Expect = 2e-09
Identities = 33/93 (35%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Frame = +3
Query: 477 KQKVTYSPTKGKDVKSLSSTYGHEGNLTNGDCCICNKKVYPMEKLSTNDKIFHKTCFRCT 656
+++ T P KG S +T+ E N+ C CNK+VY EK+++ K +H+ C RC
Sbjct: 99 EERKTSGPPKGPSKASSVTTFTGEPNM----CPRCNKRVYFAEKVTSLGKDWHRPCLRCE 154
Query: 657 KCKNALSTGNFSFNHGKPYC-TPHYVELFKKRG 752
+C L+ G + + G+PYC P Y LF +G
Sbjct: 155 RCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKG 187
Score = 53.9 bits (128), Expect = 5e-07
Identities = 25/62 (40%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Frame = +3
Query: 570 CCICNKKVYPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYC-TPHYVELFKK 746
C C+K VY EK+S+ K +HK C +C +C L+ G + + GKP+C P Y LF
Sbjct: 5 CPKCDKTVYFAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGP 64
Query: 747 RG 752
+G
Sbjct: 65 KG 66
>sp|P34416|LASP1_CAEEL LIM and SH3 domain protein F42H10.3
Length = 335
Score = 61.6 bits (148), Expect = 3e-09
Identities = 24/50 (48%), Positives = 32/50 (64%)
Frame = +3
Query: 579 CNKKVYPMEKLSTNDKIFHKTCFRCTKCKNALSTGNFSFNHGKPYCTPHY 728
C K VYP+E+L DK++HK CF+CT C L+ N+ +PYC PHY
Sbjct: 10 CGKTVYPVEELKCLDKVWHKQCFKCTVCGMTLNMKNYKGYDKRPYCDPHY 59
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,799,889
Number of Sequences: 369166
Number of extensions: 1245996
Number of successful extensions: 7245
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6291
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7085
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8148988185
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)