Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_K22
(780 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NRA2|S17A5_HUMAN Sialin (Solute carrier family 17 memb... 158 2e-38
sp|Q9V7S5|PICO_DROME Putative inorganic phosphate cotranspo... 158 2e-38
sp|Q9MZD1|S17A5_SHEEP Sialin (Solute carrier family 17 memb... 154 3e-37
sp|Q8BN82|S17A5_MOUSE Sialin (Solute carrier family 17 memb... 153 6e-37
sp|O61369|PICO_DROAN Putative inorganic phosphate cotranspo... 152 1e-36
sp|Q03567|YLD2_CAEEL Hypothetical protein C38C10.2 in chrom... 142 1e-33
sp|P34644|YOQ6_CAEEL Hypothetical protein ZK512.6 in chromo... 99 1e-20
sp|Q28722|NPT1_RABIT Renal sodium-dependent phosphate trans... 96 1e-19
sp|O00624|NPT3_HUMAN Sodium-dependent phosphate transport p... 94 3e-19
sp|Q10046|YRT3_CAEEL Hypothetical protein T07A5.3 in chromo... 89 1e-17
>sp|Q9NRA2|S17A5_HUMAN Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid
cotransporter) (AST) (Membrane glycoprotein HP59)
Length = 495
Score = 158 bits (399), Expect = 2e-38
Identities = 91/230 (39%), Positives = 120/230 (52%), Gaps = 4/230 (1%)
Frame = +1
Query: 100 CIPTRYVISIWGFLGFAVVYVLRVNLSVAILAMVNSSALNEKGVNFTPECPVS----KSL 267
C RY ++I F GF +VY LRVNLSVA++ MV+S+ E + CP K
Sbjct: 35 CCSARYNLAILAFFGFFIVYALRVNLSVALVDMVDSNTTLEDN-RTSKACPEHSAPIKVH 93
Query: 268 TNKTGNGEFVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXX 447
N+TG ++ W E QG ILG+FF+GYI Q+P G +A KIGGK G G+
Sbjct: 94 HNQTGK-KYQWDAETQGWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGILGTAVLTLF 152
Query: 448 XXXAARAGYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXX 627
AA G G LI LR LEG GE +T+PAMH M WAP +E + + I Y+G+
Sbjct: 153 TPIAADLGVGPLIVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLSISYAGAQLGTVI 212
Query: 628 XXXXXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRIS 777
W VFY G +G+ WF++W ++ TP H RIS
Sbjct: 213 SLPLSGIIC---YYMNWTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKRIS 259
>sp|Q9V7S5|PICO_DROME Putative inorganic phosphate cotransporter
Length = 529
Score = 158 bits (399), Expect = 2e-38
Identities = 85/229 (37%), Positives = 118/229 (51%), Gaps = 2/229 (0%)
Frame = +1
Query: 100 CIPTRYVISIWGFLGFAVVYVLRVNLSVAILAMVNSSALNE-KGVNFTPECPVSKSLTNK 276
C TRY ++ FLG A YV+R N+SVAI+AMVN +A+ + + EC +
Sbjct: 36 CFATRYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDD 95
Query: 277 TGNGEFVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXX 456
+ +GEF WS +QG IL +FF+GY+ Q+P G +A K G F G G+
Sbjct: 96 SQDGEFAWSSALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPV 155
Query: 457 AARAGYGW-LIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXX 633
AAR G W L A+R ++G GE P H ML W P E + +G VY+G+
Sbjct: 156 AARGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISM 215
Query: 634 XXXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISE 780
+ GGWPS+FY+ GIVG +W I + + P+ HP I E
Sbjct: 216 PLSGLLAEYGFDGGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDE 264
>sp|Q9MZD1|S17A5_SHEEP Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid
cotransporter) (Membrane glycoprotein SP55)
Length = 495
Score = 154 bits (388), Expect = 3e-37
Identities = 89/229 (38%), Positives = 117/229 (51%), Gaps = 3/229 (1%)
Frame = +1
Query: 100 CIPTRYVISIWGFLGFAVVYVLRVNLSVAILAMVNSSAL---NEKGVNFTPECPVSKSLT 270
C RY ++ F GF V+Y LRVNLSVA++ MV+S+ N K L
Sbjct: 35 CCSARYNLAFLSFFGFFVLYSLRVNLSVALVDMVDSNTTAKDNRTSYECAEHSAPIKVLH 94
Query: 271 NKTGNGEFVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXX 450
N+TG ++ W E QG ILG+FF+GYI Q+P G +A + GGK G G+
Sbjct: 95 NQTGK-KYRWDAETQGWILGSFFYGYIITQIPGGYVASRSGGKLLLGFGIFATAIFTLFT 153
Query: 451 XXAARAGYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXX 630
AA G G L+ALR LEG GE +TYPAMH M WAP +E + + I Y+G+
Sbjct: 154 PLAADFGVGALVALRALEGLGEGVTYPAMHAMWSSWAPPLERSKLLSISYAGAQLGTVVS 213
Query: 631 XXXXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRIS 777
W VFY GIVG++WFI+W + TP H I+
Sbjct: 214 LPLSGVIC---YYMNWTYVFYFFGIVGIIWFILWICLVSDTPETHKTIT 259
>sp|Q8BN82|S17A5_MOUSE Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid
cotransporter)
Length = 495
Score = 153 bits (386), Expect = 6e-37
Identities = 88/229 (38%), Positives = 118/229 (51%), Gaps = 3/229 (1%)
Frame = +1
Query: 100 CIPTRYVISIWGFLGFAVVYVLRVNLSVAILAMVNSSAL---NEKGVNFTPECPVSKSLT 270
C RY ++I F GF V+Y LRVNLSVA++ MV+S+ N K
Sbjct: 35 CCSARYNLAILAFCGFFVLYALRVNLSVALVDMVDSNTTLTDNRTSKECAEHSAPIKVHH 94
Query: 271 NKTGNGEFVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXX 450
N TG ++ W E QG ILG+FF+GYI Q+P G IA ++GGK G+G+
Sbjct: 95 NHTGK-KYKWDAETQGWILGSFFYGYIVTQIPGGYIASRVGGKLLLGLGILGTSVFTLFT 153
Query: 451 XXAARAGYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXX 630
AA G L+ LR LEG GE +T+PAMH M WAP +E + + I Y+G+
Sbjct: 154 PLAADLGVVTLVVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLTISYAGAQLGTVIS 213
Query: 631 XXXXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRIS 777
W VFY+ GIVG++WFI+W ++ TP H IS
Sbjct: 214 LPLSGIIC---YYMNWTYVFYLFGIVGIVWFILWMWIVSDTPETHKTIS 259
>sp|O61369|PICO_DROAN Putative inorganic phosphate cotransporter
Length = 483
Score = 152 bits (383), Expect = 1e-36
Identities = 81/216 (37%), Positives = 112/216 (51%), Gaps = 1/216 (0%)
Frame = +1
Query: 136 FLGFAVVYVLRVNLSVAILAMVNSSALNEKGVNFTPECPVSKSLTNKTGNGEFVWSQEIQ 315
FLG A YV+R N+SVAI+AMVN +A+ + EC + + +GEF W+ +Q
Sbjct: 3 FLGMANAYVMRTNMSVAIVAMVNHTAIKSGEEEYDDECGDRDIPIDDSQDGEFPWNAALQ 62
Query: 316 GIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXXAARAGYGW-LIAL 492
G IL +FF+GY+ Q+P G +A K G F G G+ AAR G W L A+
Sbjct: 63 GYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAAREGGVWGLCAV 122
Query: 493 RVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXXXXDANVMG 672
R ++G GE P H ML W P E + +G VY+G+ + G
Sbjct: 123 RFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGFDG 182
Query: 673 GWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISE 780
GWPS+FY+ GIVG +W I + Y P+ HP+I E
Sbjct: 183 GWPSIFYVFGIVGTVWSIAFLIFVYEDPSTHPKIDE 218
>sp|Q03567|YLD2_CAEEL Hypothetical protein C38C10.2 in chromosome III
Length = 493
Score = 142 bits (358), Expect = 1e-33
Identities = 78/227 (34%), Positives = 115/227 (50%), Gaps = 4/227 (1%)
Frame = +1
Query: 109 TRYVISIWGFLGFAVVYVLRVNLSVAILAMVNSSALNEKGVNFTPECPVSKSLTNKTGN- 285
TR+ +S+ F G V Y++R N+S A++ MVN + + GV C K +T N
Sbjct: 14 TRFALSLVMFFGCLVTYMMRTNMSFAVVCMVNENK-TDTGVEKVSRC--GKEMTPVESNS 70
Query: 286 ---GEFVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXX 456
GEF W ++ G++L +FF+GYI Q+ G +A + GGK + +
Sbjct: 71 SVIGEFDWDKQTTGMVLSSFFYGYIGSQIIGGHLASRYGGKRVVFVTILGSALLTLLNPV 130
Query: 457 AARAGYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXX 636
AAR L LR G + T+PAMHTM W P +E + + G+ Y+G+
Sbjct: 131 AARTSEYALAILRAAIGFLQGATFPAMHTMWSVWGPPLELSVLTGVTYAGAQIGNVIVLP 190
Query: 637 XXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRIS 777
+ GGWPS+FYI G+ GVLW +W +V+ PA HPRI+
Sbjct: 191 LSGFLCEYGFDGGWPSIFYIIGVFGVLWTAVWWYVSSDKPATHPRIT 237
>sp|P34644|YOQ6_CAEEL Hypothetical protein ZK512.6 in chromosome III
Length = 576
Score = 99.4 bits (246), Expect = 1e-20
Identities = 60/233 (25%), Positives = 103/233 (44%), Gaps = 1/233 (0%)
Frame = +1
Query: 85 WYNRCCIPTRYVISIWGFLGFAVVYVLRVNLSVAILAMVNSSALNEKGVNFTPECPVSKS 264
W +C R++++I +GF + + +R N A M N+T
Sbjct: 62 WIGKC--RKRWLLAILANMGFMISFGIRCNFGAAKTHMYK---------NYTDPY----- 105
Query: 265 LTNKTGNGEFVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXX 444
K EF W+ + ++ ++F+GY+ Q+PAG +A K FG G+
Sbjct: 106 --GKVHMHEFNWTIDELSVMESSYFYGYLVTQIPAGFLAAKFPPNKLFGFGIGVGAFLNI 163
Query: 445 XXXXAARAGYGWLIA-LRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXX 621
+ +L+A +++ +G + + YPAMH + YWAP ME + + ++GS+
Sbjct: 164 LLPYGFKVKSDYLVAFIQITQGLVQGVCYPAMHGVWRYWAPPMERSKLATTAFTGSYAGA 223
Query: 622 XXXXXXXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISE 780
W + FY+ G+ GV+W I+W V + PA HP IS+
Sbjct: 224 VLGLPLSAFLVS---YVSWAAPFYLYGVCGVIWAILWFCVTFEKPAFHPTISQ 273
>sp|Q28722|NPT1_RABIT Renal sodium-dependent phosphate transport protein 1
(Sodium/phosphate cotransporter 1) (Na(+)/PI
cotransporter 1) (Renal sodium-phosphate transport
protein 1) (Renal Na(+)-dependent phosphate
cotransporter 1) (Solute carrier family 18 member 1)
(NAPI-1)
Length = 465
Score = 95.9 bits (237), Expect = 1e-19
Identities = 64/227 (28%), Positives = 100/227 (44%)
Frame = +1
Query: 97 CCIPTRYVISIWGFLGFAVVYVLRVNLSVAILAMVNSSALNEKGVNFTPECPVSKSLTNK 276
C RYV++++ V+ R+ LS+ ++AMVN++ L+ +P K L N
Sbjct: 12 CFCSFRYVLALFMHFCNIVIIAQRMCLSLTMVAMVNNTNLHG-----SPNTSAEKRLDN- 65
Query: 277 TGNGEFVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXX 456
T N + WS ++QGII + F+G +Q+P G I+ K G +
Sbjct: 66 TKNPVYNWSPDVQGIIFSSIFYGAFLIQIPVGYISGIYSIKKLIGFALFLSSLVSIFIPQ 125
Query: 457 AARAGYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXX 636
AA G W+I RV++G + A H + WAP +E + + SG
Sbjct: 126 AAAVGETWIIVCRVVQGITQGTVTTAQHEIWVKWAPPLERGRLTSMSLSGFLLGPFIVLL 185
Query: 637 XXXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRIS 777
++ GWP VFYI G G ++W + Y P HP +S
Sbjct: 186 VTGIICESL---GWPMVFYIFGACGCAVCLLWFVLYYDDPKDHPCVS 229
>sp|O00624|NPT3_HUMAN Sodium-dependent phosphate transport protein 3 (Sodium/phosphate
cotransporter 3) (Na(+)/PI cotransporter 3) (Solute
carrier family 18 member 2)
Length = 436
Score = 94.4 bits (233), Expect = 3e-19
Identities = 68/226 (30%), Positives = 103/226 (45%), Gaps = 9/226 (3%)
Frame = +1
Query: 127 IWGFLGFAVVYVLRVNLSVAILAMVNSSALNEKGV-NFTPECPVSKSLTNK--------T 279
I F F ++ RV+LS+AI+AMVN++ ++G+ N + E PV+ + N T
Sbjct: 23 IMHFSNFTMI-TQRVSLSIAIIAMVNTT--QQQGLSNASTEGPVADAFNNSSISIKEFDT 79
Query: 280 GNGEFVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXXA 459
+ WS E QGII + +G I +P+G +A G K G G+ A
Sbjct: 80 KASVYQWSPETQGIIFSSINYGIILTLIPSGYLAGIFGAKKMLGAGLLISSLLTLFTPLA 139
Query: 460 ARAGYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXX 639
A G +I +R ++G + + + T+ WAP +E + + I SGS
Sbjct: 140 ADFGVILVIMVRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTTIAGSGSAFGSFIILCV 199
Query: 640 XXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRIS 777
A WP +FYI G G + ++W V Y P HHP IS
Sbjct: 200 GGLISQAL---SWPFIFYIFGSTGCVCCLLWFTVIYDDPMHHPCIS 242
>sp|Q10046|YRT3_CAEEL Hypothetical protein T07A5.3 in chromosome III
Length = 544
Score = 89.0 bits (219), Expect = 1e-17
Identities = 58/226 (25%), Positives = 100/226 (44%), Gaps = 3/226 (1%)
Frame = +1
Query: 112 RYVISIWGFLGFAVVYVLRVNLSVAILAMVNSSALNEKGVNFTPECPVSKSLTNKTGNGE 291
R+ I+I GFA+ + +R N VA MVN NFT + E
Sbjct: 47 RWQIAILAHFGFAISFGIRSNFGVAKNRMVN---------NFT-------DAYGEVHERE 90
Query: 292 FVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXXAARAG 471
F+W+ G++ +FF+GY Q+PAG +A K F +G+ +
Sbjct: 91 FLWTGAEVGMMESSFFYGYAASQIPAGVLAAKFAPNKIFMLGILVASFMNILSAISFNFH 150
Query: 472 YG---WLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXX 642
+++ ++ ++G + YPAMH + +WAP +E + + ++GS
Sbjct: 151 PYTDIFVMVVQAVQGLALGVLYPAMHGVWKFWAPPLERSKLATTAFTGSSVGVMTGLPAS 210
Query: 643 XXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISE 780
W + FY+ G+VG++W +IW +V+ +P H IS+
Sbjct: 211 AYLVSHF---SWSTPFYVFGVVGIIWSLIWMYVSSHSPETHGYISD 253
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,283,912
Number of Sequences: 369166
Number of extensions: 2151681
Number of successful extensions: 6499
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6026
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6445
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7308943600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)