Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_K21
(558 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P61962|WDR68_HUMAN WD-repeat protein 68 (WD-repeat prote... 270 1e-72
sp|Q9XGN1|TTG1_ARATH TRANSPARENT TESTA GLABRA 1 protein (TT... 179 5e-45
sp|O22469|MSI3_ARATH WD-40 repeat protein MSI3 50 5e-06
sp|Q8CFJ9|WDR24_MOUSE WD-repeat protein 24 49 8e-06
sp|Q96S15|WDR24_HUMAN WD-repeat protein 24 48 2e-05
sp|P90916|LIN53_CAEEL Trp-Asp repeats containing protein li... 47 4e-05
sp|O22468|MSI2_ARATH WD-40 repeat protein MSI2 46 7e-05
sp|Q8TEQ6|GEMI5_HUMAN Gem-associated protein 5 (Gemin5) 45 2e-04
sp|Q04225|RRB1_YEAST Ribosome assembly protein RRB1 44 4e-04
sp|O17468|HIRA_DROME HIRA protein homolog (dHIRA) 44 4e-04
>sp|P61962|WDR68_HUMAN WD-repeat protein 68 (WD-repeat protein An11 homolog)
sp|P61963|WDR68_MOUSE WD-repeat protein 68 (WD-repeat protein An11 homolog)
Length = 342
Score = 270 bits (691), Expect = 1e-72
Identities = 122/158 (77%), Positives = 137/158 (86%)
Frame = +3
Query: 6 AGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNS 185
AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP LLRL WNKQD NYLAT ++
Sbjct: 185 AGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDG 244
Query: 186 PEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIE 365
E+++LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI MPRAIE
Sbjct: 245 MEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIE 304
Query: 366 DPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 479
DPILAYTA GEIN +QW+S QPDWI+ICY + LEILRV
Sbjct: 305 DPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 342
>sp|Q9XGN1|TTG1_ARATH TRANSPARENT TESTA GLABRA 1 protein (TTG1 protein)
Length = 341
Score = 179 bits (453), Expect = 5e-45
Identities = 87/161 (54%), Positives = 112/161 (69%), Gaps = 3/161 (1%)
Frame = +3
Query: 6 AGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSA-LLRLAWNKQDANYLATFTLN 182
A G +FASV AD SVR+FDLR EHSTIIYE P LLRLAWNKQD Y+AT ++
Sbjct: 182 AWGEARVFASVSADGSVRIFDLRDKEHSTIIYESPQPDTPLLRLAWNKQDLRYMATILMD 241
Query: 183 SPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNM--PR 356
S ++++LD+R P PVA L H+ VN +AWAP S H+CSG +D QALIW++ + P
Sbjct: 242 SNKVVILDIRSPTMPVAELERHQASVNAIAWAPQSCKHICSGGDDTQALIWELPTVAGPN 301
Query: 357 AIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 479
I DP+ Y+A EINQ+QWSS QPDWI I + + +++LRV
Sbjct: 302 GI-DPMSVYSAGSEINQLQWSSSQPDWIGIAFANKMQLLRV 341
>sp|O22469|MSI3_ARATH WD-40 repeat protein MSI3
Length = 424
Score = 49.7 bits (117), Expect = 5e-06
Identities = 44/166 (26%), Positives = 80/166 (48%), Gaps = 16/166 (9%)
Frame = +3
Query: 21 DIFASVGADASVRMFDLR--HLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEI 194
+IF S G D + ++DLR ++H ++E + L++N + LAT + +S +
Sbjct: 232 NIFGSAGDDCQLVIWDLRTNQMQHQVKVHE----REINYLSFNPFNEWVLATASSDST-V 286
Query: 195 IVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDIT-------NMP 353
+ D+R P+ L+ H G V V W P+ L S ED + ++WDI +
Sbjct: 287 ALFDLRKLTAPLHVLSKHEGEVFQVEWDPNHETVLASSGEDRRLMVWDINRVGDEQLEIE 346
Query: 354 RAIED--PILAYTAAG---EINQIQWSSLQPDWI--SICYTSALEI 470
ED P L ++ G +I+ W+ +P W+ S+ ++L++
Sbjct: 347 LDAEDGPPELLFSHGGHKAKISDFAWNKDEP-WVISSVAEDNSLQV 391
Score = 33.9 bits (76), Expect = 0.28
Identities = 14/42 (33%), Positives = 23/42 (54%)
Frame = +3
Query: 219 CTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDIT 344
C P RL H G+AW+ +L SG++D + +WD++
Sbjct: 159 CDPDLRLMGHEQEGYGLAWSSFKEGYLLSGSQDQRICLWDVS 200
Score = 33.1 bits (74), Expect = 0.48
Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Frame = +3
Query: 132 LAWNKQDANYLATFTLNSPEIIVLDMRVPCT-----PVARLNNHRGCVNGVAWAPHSSCH 296
LAW+ YL + + + I + D+ T P+ H+ + VAW +
Sbjct: 175 LAWSSFKEGYLLSGSQDQ-RICLWDVSATATDKVLNPMHVYEGHQSIIEDVAWHMKNENI 233
Query: 297 LCSGAEDCQALIWDI 341
S +DCQ +IWD+
Sbjct: 234 FGSAGDDCQLVIWDL 248
>sp|Q8CFJ9|WDR24_MOUSE WD-repeat protein 24
Length = 790
Score = 48.9 bits (115), Expect = 8e-06
Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Frame = +3
Query: 18 RDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLN-SPEI 194
R A+ G D V+++D+ + I+ +++ R+ W + ++LAT ++ I
Sbjct: 220 RGWLATGGRDKMVKVWDMT-THRAKEIHCVQTIASVARVKWRPECRHHLATCSMMVDHNI 278
Query: 195 IVLDMRVPCTPVARLNNHRGCVNGVAWA-PHSSCHLCSGAED---CQALIWDITNMPRAI 362
V D+R P P A HR G+AW PH L SG++D CQ L D +
Sbjct: 279 YVWDVRRPFVPAAMFEEHRDVTTGIAWRHPHDPSFLLSGSKDSTLCQHLFRDASQPVERA 338
Query: 363 EDPILAYTAAGEI 401
L Y G++
Sbjct: 339 NPEGLCYGLFGDL 351
>sp|Q96S15|WDR24_HUMAN WD-repeat protein 24
Length = 920
Score = 47.8 bits (112), Expect = 2e-05
Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Frame = +3
Query: 18 RDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLN-SPEI 194
R A+ G D V+++D+ + ++ +++ R+ W + ++LAT ++ I
Sbjct: 350 RGWLATGGRDKMVKVWDMT-THRAKEMHCVQTIASVARVKWRPECRHHLATCSMMVDHNI 408
Query: 195 IVLDMRVPCTPVARLNNHRGCVNGVAWA-PHSSCHLCSGAED---CQALIWDITNMPRAI 362
V D+R P P A HR G+AW PH L SG++D CQ L D +
Sbjct: 409 YVWDVRRPFVPAAMFEEHRDVTTGIAWRHPHDPSFLLSGSKDSSLCQHLFRDASQPVERA 468
Query: 363 EDPILAYTAAGEI 401
L Y G++
Sbjct: 469 NPEGLCYGLFGDL 481
>sp|P90916|LIN53_CAEEL Trp-Asp repeats containing protein lin-53 (Abnormal cell lineage
protein 53)
Length = 385
Score = 46.6 bits (109), Expect = 4e-05
Identities = 42/162 (25%), Positives = 76/162 (46%), Gaps = 10/162 (6%)
Frame = +3
Query: 24 IFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVL 203
+F SVG D + ++D+R I D + + + LA+N LAT + + + +
Sbjct: 205 VFGSVGDDKKLLIWDVRTSTPGHCI--DAHSAEVNCLAFNPYSEFILATGSADKT-VALW 261
Query: 204 DMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNM--PRAIED--- 368
D+R + +HR + V W+PH+ L S D + +WD++ + ++ ED
Sbjct: 262 DLRNLRMKLHSFESHRDEIFQVQWSPHNETILASSGTDKRLHVWDLSKIGEDQSAEDAED 321
Query: 369 --PILAYTAAG---EINQIQWSSLQPDWISICYTSALEILRV 479
P L + G +I+ W+ +P W+ +C S IL+V
Sbjct: 322 GPPELLFIHGGHTAKISDFSWNPNEP-WV-VCSVSEDNILQV 361
>sp|O22468|MSI2_ARATH WD-40 repeat protein MSI2
Length = 415
Score = 45.8 bits (107), Expect = 7e-05
Identities = 40/166 (24%), Positives = 80/166 (48%), Gaps = 16/166 (9%)
Frame = +3
Query: 21 DIFASVGADASVRMFDLR--HLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEI 194
++F S G D + ++D R ++H ++E + L++N + LAT + +S +
Sbjct: 231 NLFGSAGEDGRLVIWDTRTNQMQHQVKVHE----REVNYLSFNPFNEWVLATASSDST-V 285
Query: 195 IVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRA----- 359
+ D+R P+ +++H G V V W P+ L S ED + ++WD+ +
Sbjct: 286 ALFDLRKLNAPLHVMSSHEGEVFQVEWDPNHETVLASSGEDRRLMVWDLNRVGEEQLEIE 345
Query: 360 --IED--PILAYTAAG---EINQIQWSSLQPDWI--SICYTSALEI 470
ED P L ++ G +I+ W+ +P W+ S+ ++L++
Sbjct: 346 LDAEDGPPELLFSHGGHKAKISDFAWNKNEP-WVIASVAEDNSLQV 390
Score = 36.6 bits (83), Expect = 0.043
Identities = 15/46 (32%), Positives = 26/46 (56%)
Frame = +3
Query: 219 CTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPR 356
C P RL H G++W+P +L SG++D + +WD++ P+
Sbjct: 158 CDPDLRLVGHDKEGYGLSWSPFKEGYLLSGSQDQKICLWDVSATPQ 203
Score = 28.9 bits (63), Expect = 9.0
Identities = 28/122 (22%), Positives = 52/122 (42%), Gaps = 16/122 (13%)
Frame = +3
Query: 24 IFASVGADASVRMFDLRHLE--------HSTIIYE---DPNKSALLRLAWNKQDANYLAT 170
+ A+ +D++V +FDLR L H +++ DPN +L + + L
Sbjct: 275 VLATASSDSTVALFDLRKLNAPLHVMSSHEGEVFQVEWDPNHETVLA---SSGEDRRLMV 331
Query: 171 FTLN--SPEIIVLDMRVPCTPVARLNNHRGC---VNGVAWAPHSSCHLCSGAEDCQALIW 335
+ LN E + +++ P L +H G ++ AW + + S AED +W
Sbjct: 332 WDLNRVGEEQLEIELDAEDGPPELLFSHGGHKAKISDFAWNKNEPWVIASVAEDNSLQVW 391
Query: 336 DI 341
+
Sbjct: 392 QM 393
>sp|Q8TEQ6|GEMI5_HUMAN Gem-associated protein 5 (Gemin5)
Length = 1508
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 17/156 (10%)
Frame = +3
Query: 24 IFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQ-----DANYLATFTLNSP 188
I A D S+ +F + +L+ I + + + ++W+ + + +YL N+
Sbjct: 550 IMALGNEDGSIEIFQIPNLKLICTIQQ--HHKLVNTISWHHEHGSQPELSYLMASGSNNA 607
Query: 189 EIIVLDMRV--------PCT---PVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIW 335
I V +++ P T P L+ H + VAW+PH L S + D A +W
Sbjct: 608 VIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVW 667
Query: 336 DITNMPRAIEDPILAYTA-AGEINQIQWSSLQPDWI 440
D E+P+ + G + + WS L PD I
Sbjct: 668 DALR-----EEPLCNFRGHQGRLLCVAWSPLDPDCI 698
>sp|Q04225|RRB1_YEAST Ribosome assembly protein RRB1
Length = 511
Score = 43.5 bits (101), Expect = 4e-04
Identities = 28/114 (24%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Frame = +3
Query: 24 IFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVL 203
+FA+ G D +R++D R +H I + + + ++W+ + LA+ N V
Sbjct: 336 VFATAGCDGYIRIWDTRSKKHKPAISVKASNTDVNVISWSDKIGYLLASGDDNGTWG-VW 394
Query: 204 DMRV-------PCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDIT 344
D+R PVA+ + H+G + +A+ P + G+ED +WD++
Sbjct: 395 DLRQFTPSNADAVQPVAQYDFHKGAITSIAFNPLDESIVAVGSEDNTVTLWDLS 448
>sp|O17468|HIRA_DROME HIRA protein homolog (dHIRA)
Length = 1047
Score = 43.5 bits (101), Expect = 4e-04
Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 2/101 (1%)
Frame = +3
Query: 123 LLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLC 302
+L LAW+ D YLA+ ++++ +I+ D + VA L H G V GV+W P L
Sbjct: 132 VLDLAWSPNDV-YLASCSIDNT-VIIWDAQAFPHSVATLKGHTGLVKGVSWDPLGR-FLA 188
Query: 303 SGAEDCQALIWDITN--MPRAIEDPILAYTAAGEINQIQWS 419
S ++D IW+ N + I +P I ++ WS
Sbjct: 189 SQSDDRSIKIWNTMNWSLSHTITEPFEECGGTTHILRLSWS 229
Score = 29.6 bits (65), Expect = 5.3
Identities = 12/36 (33%), Positives = 22/36 (61%)
Frame = +3
Query: 228 VARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIW 335
+ +++ H CVN V W+ + +L SG++D +IW
Sbjct: 63 LCQMDQHLACVNCVRWSQNGQ-NLASGSDDKLIMIW 97
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,168,102
Number of Sequences: 369166
Number of extensions: 1219361
Number of successful extensions: 2994
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2791
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2971
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3980545740
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)