Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_K13
(736 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P51893|SAHHA_XENLA Adenosylhomocysteinase A (S-adenosyl-... 326 4e-89
sp|O93477|SAHHB_XENLA Adenosylhomocysteinase B (S-adenosyl-... 325 6e-89
sp|P50247|SAHH_MOUSE Adenosylhomocysteinase (S-adenosyl-L-h... 322 8e-88
sp|P10760|SAHH_RAT Adenosylhomocysteinase (S-adenosyl-L-hom... 320 2e-87
sp|P27604|SAHH_CAEEL Adenosylhomocysteinase (S-adenosyl-L-h... 318 9e-87
sp|P23526|SAHH_HUMAN Adenosylhomocysteinase (S-adenosyl-L-h... 315 8e-86
sp|Q710C4|SAHH_PIG Adenosylhomocysteinase (S-adenosyl-L-hom... 314 2e-85
sp|Q27580|SAHH_DROME Adenosylhomocysteinase (S-adenosyl-L-h... 312 7e-85
sp|O76757|SAHH_ANOGA Adenosylhomocysteinase (S-adenosyl-L-h... 304 1e-82
sp|O13639|SAHH_SCHPO Adenosylhomocysteinase (S-adenosyl-L-h... 300 3e-81
>sp|P51893|SAHHA_XENLA Adenosylhomocysteinase A (S-adenosyl-L-homocysteine hydrolase A)
(AdoHcyase A)
Length = 433
Score = 326 bits (835), Expect = 4e-89
Identities = 156/202 (77%), Positives = 175/202 (86%)
Frame = +2
Query: 2 ALRAYGCRVLVSEIDPINALQAAMEGYEVTTVEEAVKKARIFVTATGCKDIIVGRHFEQM 181
ALRA+G RV+++EIDPINALQAAMEGYEVTT++EA K+ IFVT TGC DI+ GRHFE M
Sbjct: 232 ALRAFGARVIITEIDPINALQAAMEGYEVTTMDEASKEGNIFVTTTGCADIVEGRHFENM 291
Query: 182 LDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCA 361
DDSIVCNIGHFDIE++ KWL EN K IKPQVDRY LKNGRHIILLAEGRLVNLGCA
Sbjct: 292 KDDSIVCNIGHFDIELDVKWLNENAVKKVNIKPQVDRYLLKNGRHIILLAEGRLVNLGCA 351
Query: 362 HGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLT 541
GHPSFVMSNSFTNQV+AQIELWT TD+Y VGVYFLPKKLDE VA AHL+ LGVKLTKLT
Sbjct: 352 MGHPSFVMSNSFTNQVMAQIELWTNTDKYPVGVYFLPKKLDEAVAAAHLDKLGVKLTKLT 411
Query: 542 PEQSEYLSVPIQGPYKPDHYRY 607
+Q++YL + +GP+KPDHYRY
Sbjct: 412 DKQAKYLGLDKEGPFKPDHYRY 433
>sp|O93477|SAHHB_XENLA Adenosylhomocysteinase B (S-adenosyl-L-homocysteine hydrolase B)
(AdoHcyase B)
Length = 433
Score = 325 bits (834), Expect = 6e-89
Identities = 155/202 (76%), Positives = 175/202 (86%)
Frame = +2
Query: 2 ALRAYGCRVLVSEIDPINALQAAMEGYEVTTVEEAVKKARIFVTATGCKDIIVGRHFEQM 181
ALRA+G RVL++EIDPINALQAAMEGYEVTT++EA K+ IFVT TGC DI+ GRHFE M
Sbjct: 232 ALRAFGARVLITEIDPINALQAAMEGYEVTTMDEASKEGNIFVTTTGCADIVEGRHFENM 291
Query: 182 LDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCA 361
DDSIVCNIGHFD+E++ KWL +N K IKPQVDRY LKNGRHIILLAEGRLVNLGCA
Sbjct: 292 KDDSIVCNIGHFDVELDVKWLNDNAAKKINIKPQVDRYLLKNGRHIILLAEGRLVNLGCA 351
Query: 362 HGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLT 541
GHPSFVMSNSFTNQV+AQIELWT TD+Y VGVYFLPKKLDE VA AHL+ LGVKLTKLT
Sbjct: 352 MGHPSFVMSNSFTNQVMAQIELWTNTDKYPVGVYFLPKKLDEAVAAAHLDKLGVKLTKLT 411
Query: 542 PEQSEYLSVPIQGPYKPDHYRY 607
+Q++YL + +GP+KPDHYRY
Sbjct: 412 DKQAKYLGLDKEGPFKPDHYRY 433
>sp|P50247|SAHH_MOUSE Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase) (Liver copper binding protein) (CUBP)
Length = 432
Score = 322 bits (824), Expect = 8e-88
Identities = 153/202 (75%), Positives = 174/202 (86%)
Frame = +2
Query: 2 ALRAYGCRVLVSEIDPINALQAAMEGYEVTTVEEAVKKARIFVTATGCKDIIVGRHFEQM 181
ALR +G RV+++EIDPINALQAAMEGYEVTT++EA K+ IFVT TGC DII+GRHFEQM
Sbjct: 231 ALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQM 290
Query: 182 LDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCA 361
DD+IVCNIGHFD+E++ KWL EN K IKPQVDRY LKNGR IILLAEGRLVNLGCA
Sbjct: 291 KDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYWLKNGRRIILLAEGRLVNLGCA 350
Query: 362 HGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLT 541
GHPSFVMSNSFTNQV+AQIELWT D+Y VGV+FLPKKLDE VA+AHL L VKLTKLT
Sbjct: 351 MGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLT 410
Query: 542 PEQSEYLSVPIQGPYKPDHYRY 607
+Q++YL +PI GP+KPDHYRY
Sbjct: 411 EKQAQYLGMPINGPFKPDHYRY 432
>sp|P10760|SAHH_RAT Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 320 bits (820), Expect = 2e-87
Identities = 152/202 (75%), Positives = 173/202 (85%)
Frame = +2
Query: 2 ALRAYGCRVLVSEIDPINALQAAMEGYEVTTVEEAVKKARIFVTATGCKDIIVGRHFEQM 181
ALR +G RV+++EIDPINALQAAMEGYEVTT++EA K+ IFVT TGC DII+GRHFEQM
Sbjct: 231 ALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQM 290
Query: 182 LDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCA 361
DD+IVCNIGHFD+E++ KWL EN K IKPQVDRY LKNG IILLAEGRLVNLGCA
Sbjct: 291 KDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCA 350
Query: 362 HGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLT 541
GHPSFVMSNSFTNQV+AQIELWT D+Y VGV+FLPKKLDE VA+AHL L VKLTKLT
Sbjct: 351 MGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLT 410
Query: 542 PEQSEYLSVPIQGPYKPDHYRY 607
+Q++YL +PI GP+KPDHYRY
Sbjct: 411 EKQAQYLGMPINGPFKPDHYRY 432
>sp|P27604|SAHH_CAEEL Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase) (Dumpy-14 protein)
Length = 437
Score = 318 bits (815), Expect = 9e-87
Identities = 151/205 (73%), Positives = 173/205 (84%), Gaps = 3/205 (1%)
Frame = +2
Query: 2 ALRAYGCRVLVSEIDPINALQAAMEGYEVTTVEEAVKKARIFVTATGCKDIIVGRHFEQM 181
+L+A+G RV+V+EIDPINALQAAMEGYEVTT+EEA KA I VT TGCKDI+ G+HFE +
Sbjct: 233 SLKAFGSRVIVTEIDPINALQAAMEGYEVTTLEEAAPKANIIVTTTGCKDIVTGKHFELL 292
Query: 182 LDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCA 361
+D+IVCN+GHFD E++ KWL N KDTIKPQVDRYTLKNGRH+ILLAEGRLVNLGCA
Sbjct: 293 PNDAIVCNVGHFDCEIDVKWLNTNATKKDTIKPQVDRYTLKNGRHVILLAEGRLVNLGCA 352
Query: 362 HGHPSFVMSNSFTNQVLAQIELWTK---TDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLT 532
GHPSFVMSNSFTNQVLAQ+ELWTK +YK+G+Y LPK LDEEVA HL LGVKLT
Sbjct: 353 TGHPSFVMSNSFTNQVLAQVELWTKFGTPQEYKLGLYVLPKTLDEEVAYLHLAQLGVKLT 412
Query: 533 KLTPEQSEYLSVPIQGPYKPDHYRY 607
KL+ EQ+ YL VP+ GPYKPDHYRY
Sbjct: 413 KLSDEQASYLGVPVAGPYKPDHYRY 437
>sp|P23526|SAHH_HUMAN Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 315 bits (807), Expect = 8e-86
Identities = 150/202 (74%), Positives = 172/202 (85%)
Frame = +2
Query: 2 ALRAYGCRVLVSEIDPINALQAAMEGYEVTTVEEAVKKARIFVTATGCKDIIVGRHFEQM 181
ALR +G RV+++EIDPINALQAAMEGYEVTT++EA ++ IFVT TGC DII+GRHFEQM
Sbjct: 231 ALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQM 290
Query: 182 LDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCA 361
DD+IVCNIGHFD+E++ KWL EN K IKPQVDRY LKNGR IILLAEGRLVNLGCA
Sbjct: 291 KDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCA 350
Query: 362 HGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLT 541
GHPSFVMSNSFTNQV+AQIELWT D+Y VGV+FLPKKLDE VA+AHL L VKLTKLT
Sbjct: 351 MGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLT 410
Query: 542 PEQSEYLSVPIQGPYKPDHYRY 607
+Q++YL + GP+KPDHYRY
Sbjct: 411 EKQAQYLGMSCDGPFKPDHYRY 432
>sp|Q710C4|SAHH_PIG Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 314 bits (804), Expect = 2e-85
Identities = 150/202 (74%), Positives = 172/202 (85%)
Frame = +2
Query: 2 ALRAYGCRVLVSEIDPINALQAAMEGYEVTTVEEAVKKARIFVTATGCKDIIVGRHFEQM 181
ALR +G RV+++EIDPINALQAAMEGYEVTT++EA ++ IFVT TGC DII+GRHFEQM
Sbjct: 231 ALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQM 290
Query: 182 LDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCA 361
DD+IVCNIGHFD+E++ KWL EN K IKPQVDRY LKNG IILLAEGRLVNLGCA
Sbjct: 291 KDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCA 350
Query: 362 HGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLT 541
GHPSFVMSNSFTNQVLAQIELWT D+Y VGV+FLPKKLDE VA+AHL L VKLTKLT
Sbjct: 351 MGHPSFVMSNSFTNQVLAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLT 410
Query: 542 PEQSEYLSVPIQGPYKPDHYRY 607
+Q++YL + +GP+KPDHYRY
Sbjct: 411 EKQAQYLGMSREGPFKPDHYRY 432
>sp|Q27580|SAHH_DROME Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 312 bits (799), Expect = 7e-85
Identities = 149/202 (73%), Positives = 172/202 (85%)
Frame = +2
Query: 2 ALRAYGCRVLVSEIDPINALQAAMEGYEVTTVEEAVKKARIFVTATGCKDIIVGRHFEQM 181
AL+ +G RV+V+E+DPINALQAAMEGYEVTT+EEA K+A IFVT TGC+DII H +QM
Sbjct: 231 ALKGFGGRVIVTEVDPINALQAAMEGYEVTTMEEASKEASIFVTTTGCRDIITSVHLQQM 290
Query: 182 LDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCA 361
DD+IVCNIGHFDIE++ WL N K K +KPQVDRYT+++G+HIILLAEGRLVNLGCA
Sbjct: 291 PDDAIVCNIGHFDIEIDVDWLNANAKEKVNVKPQVDRYTMQSGKHIILLAEGRLVNLGCA 350
Query: 362 HGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLT 541
HGHPSFVMSNSFTNQVLAQIELWTK+D+Y VGV+ LPK LDEEVA HLE LGVKLTKLT
Sbjct: 351 HGHPSFVMSNSFTNQVLAQIELWTKSDKYAVGVHVLPKILDEEVASLHLEKLGVKLTKLT 410
Query: 542 PEQSEYLSVPIQGPYKPDHYRY 607
+Q+ YL V GP+KPDHYRY
Sbjct: 411 EKQATYLGVSQTGPFKPDHYRY 432
>sp|O76757|SAHH_ANOGA Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 432
Score = 304 bits (779), Expect = 1e-82
Identities = 148/202 (73%), Positives = 166/202 (82%)
Frame = +2
Query: 2 ALRAYGCRVLVSEIDPINALQAAMEGYEVTTVEEAVKKARIFVTATGCKDIIVGRHFEQM 181
ALR G RVL++EIDPINALQAAMEG EVTT+EEA K+A+IFVT TGC DII+G HF M
Sbjct: 231 ALRGSGGRVLITEIDPINALQAAMEGKEVTTMEEASKEAQIFVTTTGCTDIIMGEHFLNM 290
Query: 182 LDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCA 361
DDSIVCNIGHFD E+ WL EN K IKPQVDRY L NG HIILLAEGRLVNLGCA
Sbjct: 291 KDDSIVCNIGHFDCEINVTWLQENAVEKVNIKPQVDRYRLANGNHIILLAEGRLVNLGCA 350
Query: 362 HGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLT 541
GH SFVMSNSFTNQVLAQIELWT +QY +GV+ LPKKLD+EVA HL+ LGVKLTKL+
Sbjct: 351 MGHSSFVMSNSFTNQVLAQIELWTNREQYAIGVHVLPKKLDDEVAALHLDKLGVKLTKLS 410
Query: 542 PEQSEYLSVPIQGPYKPDHYRY 607
Q EYL++P++GPYKP+HYRY
Sbjct: 411 ARQPEYLNLPVEGPYKPEHYRY 432
>sp|O13639|SAHH_SCHPO Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase)
(AdoHcyase)
Length = 433
Score = 300 bits (768), Expect = 3e-81
Identities = 143/202 (70%), Positives = 166/202 (82%)
Frame = +2
Query: 2 ALRAYGCRVLVSEIDPINALQAAMEGYEVTTVEEAVKKARIFVTATGCKDIIVGRHFEQM 181
+LR+ G RV+V+E+DPINALQAAM+G+EVTT+EEAVK+ +IFVT TGC+DII G HF +M
Sbjct: 232 SLRSQGARVIVTEVDPINALQAAMDGFEVTTMEEAVKEGQIFVTTTGCRDIIRGEHFNEM 291
Query: 182 LDDSIVCNIGHFDIEVEAKWLYENCKSKDTIKPQVDRYTLKNGRHIILLAEGRLVNLGCA 361
+DSIVCNIGHFD+E++ WL N K IKPQVDRY LKNGRHIILLA+GRLVNLGCA
Sbjct: 292 KEDSIVCNIGHFDVEIDVAWLKANAKDVVNIKPQVDRYELKNGRHIILLADGRLVNLGCA 351
Query: 362 HGHPSFVMSNSFTNQVLAQIELWTKTDQYKVGVYFLPKKLDEEVAQAHLEHLGVKLTKLT 541
GHPSFVMS SFTNQVLAQI LWT Y +GV+ LPKKLDEEVA+ HL LGVKLT LT
Sbjct: 352 TGHPSFVMSCSFTNQVLAQIALWTDNTSYPLGVHMLPKKLDEEVARLHLGKLGVKLTTLT 411
Query: 542 PEQSEYLSVPIQGPYKPDHYRY 607
QS+YL +P+ GPYK DHYRY
Sbjct: 412 SVQSDYLGIPVDGPYKADHYRY 433
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,457,329
Number of Sequences: 369166
Number of extensions: 1775765
Number of successful extensions: 4994
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4740
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4888
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6582889600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)