Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_K06
(856 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P24643|CALX_CANFA Calnexin precursor (pp90) 379 e-105
sp|P35565|CALX_RAT Calnexin precursor 379 e-105
sp|P35564|CALX_MOUSE Calnexin precursor 379 e-105
sp|Q5R440|CALX_PONPY Calnexin precursor 376 e-104
sp|P27824|CALX_HUMAN Calnexin precursor (Major histocompati... 375 e-104
sp|P52194|CLGN_MOUSE Calmegin precursor (MEG 1 antigen) (Ca... 338 1e-92
sp|O14967|CLGN_HUMAN Calmegin precursor 333 4e-91
sp|Q38798|CALX2_ARATH Calnexin homolog 2 precursor 281 1e-75
sp|P29402|CALX1_ARATH Calnexin homolog 1 precursor 279 8e-75
sp|Q39817|CALX_SOYBN Calnexin homolog precursor 277 3e-74
>sp|P24643|CALX_CANFA Calnexin precursor (pp90)
Length = 593
Score = 379 bits (973), Expect = e-105
Identities = 167/272 (61%), Positives = 210/272 (77%)
Frame = +3
Query: 3 IYEEKHAKKSSSDLDRHFTDKKTHLYTLVVNSDNTFEIFVDQTLVNSGSLLKDFEPSVNP 182
+YEEKHAK+ +DL +FTDKKTHLYTL++N DN+FEI VDQ++VNSG+LL D P VNP
Sbjct: 214 VYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSIVNSGNLLNDMTPPVNP 273
Query: 183 PKEIDDPNDVKPEDWDDTPKISDPDAVKPGDWDDSAPEYIEDEKAVKPDGWLENEPLTVP 362
+EI+DP D KPEDWD+ PKI DPDAVKP DW++ AP I DE+A KPDGWL++EP VP
Sbjct: 274 SREIEDPEDQKPEDWDERPKIPDPDAVKPDDWNEDAPAKIPDEEATKPDGWLDDEPEYVP 333
Query: 363 DEKSEKPKDWDDEMDGEWEAPRIDNPLCKDAPGCGPWKSPKIKNPNYKGVWTAPMIDNPK 542
D +EKP+DWD++MDGEWEAP+I NP C+ APGCG W+ P I NPNYKG W PMIDNP
Sbjct: 334 DPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPN 393
Query: 543 YKGVWKARRIPNADYFEDAQPYKMTPIGAIGLELWSMSDEIVFDNFIIVDNKKAADDFAA 722
Y+G+WK R+IPN D+FED +P+KMTP AIGLELWSM+ +I FDNFI+ +++ DD+A
Sbjct: 394 YQGIWKPRKIPNPDFFEDLEPFKMTPFSAIGLELWSMTSDIFFDNFIVCGDRRVVDDWAN 453
Query: 723 ETWVVKKDAERRADPNSQSVVDAIREATSERP 818
+ W +KK A+ A+P VV + EA ERP
Sbjct: 454 DGWGLKKAADGAAEP---GVVGQMIEAAEERP 482
>sp|P35565|CALX_RAT Calnexin precursor
Length = 591
Score = 379 bits (972), Expect = e-105
Identities = 166/272 (61%), Positives = 211/272 (77%)
Frame = +3
Query: 3 IYEEKHAKKSSSDLDRHFTDKKTHLYTLVVNSDNTFEIFVDQTLVNSGSLLKDFEPSVNP 182
+YEEKHAK+ +DL +FTDKKTHLYTL++N DN+FEI VDQ++VNSG+LL D P VNP
Sbjct: 214 VYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNP 273
Query: 183 PKEIDDPNDVKPEDWDDTPKISDPDAVKPGDWDDSAPEYIEDEKAVKPDGWLENEPLTVP 362
+EI+DP D KPEDWD+ PKI+DPDAVKP DWD+ AP I DE+A KP+GWL++EP +P
Sbjct: 274 SREIEDPEDRKPEDWDERPKIADPDAVKPDDWDEDAPSKIPDEEATKPEGWLDDEPEYIP 333
Query: 363 DEKSEKPKDWDDEMDGEWEAPRIDNPLCKDAPGCGPWKSPKIKNPNYKGVWTAPMIDNPK 542
D +EKP+DWD++MDGEWEAP+I NP C+ APGCG W+ P I NPNYKG W PMIDNP
Sbjct: 334 DPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPN 393
Query: 543 YKGVWKARRIPNADYFEDAQPYKMTPIGAIGLELWSMSDEIVFDNFIIVDNKKAADDFAA 722
Y+G+WK R+IPN D+FED +P++MTP AIGLELWSM+ +I FDNFII +++ DD+A
Sbjct: 394 YQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIISGDRRVVDDWAN 453
Query: 723 ETWVVKKDAERRADPNSQSVVDAIREATSERP 818
+ W +KK A+ A+P VV + EA ERP
Sbjct: 454 DGWGLKKAADGAAEP---GVVGQMLEAAEERP 482
>sp|P35564|CALX_MOUSE Calnexin precursor
Length = 591
Score = 379 bits (972), Expect = e-105
Identities = 167/272 (61%), Positives = 211/272 (77%)
Frame = +3
Query: 3 IYEEKHAKKSSSDLDRHFTDKKTHLYTLVVNSDNTFEIFVDQTLVNSGSLLKDFEPSVNP 182
+YEEKHAK+ +DL +FTDKKTHLYTL++N DN+FEI VDQ++VNSG+LL D P VNP
Sbjct: 214 VYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNP 273
Query: 183 PKEIDDPNDVKPEDWDDTPKISDPDAVKPGDWDDSAPEYIEDEKAVKPDGWLENEPLTVP 362
+EI+DP D KPEDWD+ PKI+DPDAVKP DWD+ AP I DE+A KP+GWL++EP +P
Sbjct: 274 SREIEDPEDRKPEDWDERPKIADPDAVKPDDWDEDAPSKIPDEEATKPEGWLDDEPEYIP 333
Query: 363 DEKSEKPKDWDDEMDGEWEAPRIDNPLCKDAPGCGPWKSPKIKNPNYKGVWTAPMIDNPK 542
D +EKP+DWD++MDGEWEAP+I NP C+ APGCG W+ P I NPNYKG W PMIDNP
Sbjct: 334 DPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPN 393
Query: 543 YKGVWKARRIPNADYFEDAQPYKMTPIGAIGLELWSMSDEIVFDNFIIVDNKKAADDFAA 722
Y+G+WK R+IPN D+FED +P+KMTP AIGLELWSM+ +I FDNFII +++ DD+A
Sbjct: 394 YQGIWKPRKIPNPDFFEDLEPFKMTPFSAIGLELWSMTSDIFFDNFIISGDRRVVDDWAN 453
Query: 723 ETWVVKKDAERRADPNSQSVVDAIREATSERP 818
+ W +KK A+ A+P VV + EA ERP
Sbjct: 454 DGWGLKKAADGAAEP---GVVLQMLEAAEERP 482
>sp|Q5R440|CALX_PONPY Calnexin precursor
Length = 592
Score = 376 bits (965), Expect = e-104
Identities = 167/272 (61%), Positives = 210/272 (77%)
Frame = +3
Query: 3 IYEEKHAKKSSSDLDRHFTDKKTHLYTLVVNSDNTFEIFVDQTLVNSGSLLKDFEPSVNP 182
IYEEKHAK+ +DL +FTDKKTHLYTL++N DN+FEI VDQ++VNSG+LL D P VNP
Sbjct: 213 IYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNP 272
Query: 183 PKEIDDPNDVKPEDWDDTPKISDPDAVKPGDWDDSAPEYIEDEKAVKPDGWLENEPLTVP 362
+EI+DP D KPEDWD+ PKI DP+AVKP DWD+ AP I DE+A KP+GWL++EP VP
Sbjct: 273 SREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVP 332
Query: 363 DEKSEKPKDWDDEMDGEWEAPRIDNPLCKDAPGCGPWKSPKIKNPNYKGVWTAPMIDNPK 542
D +EKP+DWD++MDGEWEAP+I NP C+ APGCG W+ P I NPNYKG W PMIDNP
Sbjct: 333 DPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPS 392
Query: 543 YKGVWKARRIPNADYFEDAQPYKMTPIGAIGLELWSMSDEIVFDNFIIVDNKKAADDFAA 722
Y+G+WK R+IPN D+FED +P++MTP AIGLELWSM+ +I FDNFII +++ DD+A
Sbjct: 393 YQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDWAN 452
Query: 723 ETWVVKKDAERRADPNSQSVVDAIREATSERP 818
+ W +KK A+ A+P VV + EA ERP
Sbjct: 453 DGWGLKKAADGAAEP---GVVGQMIEAAEERP 481
>sp|P27824|CALX_HUMAN Calnexin precursor (Major histocompatibility complex class I
antigen-binding protein p88) (p90) (IP90)
Length = 592
Score = 375 bits (964), Expect = e-104
Identities = 167/272 (61%), Positives = 210/272 (77%)
Frame = +3
Query: 3 IYEEKHAKKSSSDLDRHFTDKKTHLYTLVVNSDNTFEIFVDQTLVNSGSLLKDFEPSVNP 182
IYEEKHAK+ +DL +FTDKKTHLYTL++N DN+FEI VDQ++VNSG+LL D P VNP
Sbjct: 213 IYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNP 272
Query: 183 PKEIDDPNDVKPEDWDDTPKISDPDAVKPGDWDDSAPEYIEDEKAVKPDGWLENEPLTVP 362
+EI+DP D KPEDWD+ PKI DP+AVKP DWD+ AP I DE+A KP+GWL++EP VP
Sbjct: 273 SREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVP 332
Query: 363 DEKSEKPKDWDDEMDGEWEAPRIDNPLCKDAPGCGPWKSPKIKNPNYKGVWTAPMIDNPK 542
D +EKP+DWD++MDGEWEAP+I NP C+ APGCG W+ P I NPNYKG W PMIDNP
Sbjct: 333 DPDAEKPEDWDEDMDGEWEAPQIANPRCESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPS 392
Query: 543 YKGVWKARRIPNADYFEDAQPYKMTPIGAIGLELWSMSDEIVFDNFIIVDNKKAADDFAA 722
Y+G+WK R+IPN D+FED +P++MTP AIGLELWSM+ +I FDNFII +++ DD+A
Sbjct: 393 YQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDWAN 452
Query: 723 ETWVVKKDAERRADPNSQSVVDAIREATSERP 818
+ W +KK A+ A+P VV + EA ERP
Sbjct: 453 DGWGLKKAADGAAEP---GVVGQMIEAAEERP 481
>sp|P52194|CLGN_MOUSE Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6)
Length = 611
Score = 338 bits (866), Expect = 1e-92
Identities = 152/272 (55%), Positives = 193/272 (70%)
Frame = +3
Query: 3 IYEEKHAKKSSSDLDRHFTDKKTHLYTLVVNSDNTFEIFVDQTLVNSGSLLKDFEPSVNP 182
++EEKHAK DL FTD+KTHLYTLV+N D+TFE+ +DQ +VN G+LL D P +NP
Sbjct: 204 VFEEKHAKPPDVDLKEFFTDRKTHLYTLVMNPDDTFEVLIDQKVVNQGTLLDDVVPPINP 263
Query: 183 PKEIDDPNDVKPEDWDDTPKISDPDAVKPGDWDDSAPEYIEDEKAVKPDGWLENEPLTVP 362
P+EIDDP+D KPE+WDD KI DP AVKP DWD++ P IED AVKPDGWL++EP +P
Sbjct: 264 preIDDPSDKKPEEWDDRAKIPDPTAVKPEDWDENEPAQIEDSSAVKPDGWLDDEPKFIP 323
Query: 363 DEKSEKPKDWDDEMDGEWEAPRIDNPLCKDAPGCGPWKSPKIKNPNYKGVWTAPMIDNPK 542
+ K+EKP+DW D+MDGEWEAP I NP C+ GCG WK P I NP YKG+W PMI+NP
Sbjct: 324 NPKAEKPEDWSDDMDGEWEAPHIPNPACQ--IGCGEWKPPMIDNPKYKGIWRPPMINNPN 381
Query: 543 YKGVWKARRIPNADYFEDAQPYKMTPIGAIGLELWSMSDEIVFDNFIIVDNKKAADDFAA 722
Y+G+W ++IPN DYFED P+ +T A+GLELWSM+ +I FDNFII K+ AD +A
Sbjct: 382 YQGLWSPQKIPNPDYFEDDHPFLLTSFSALGLELWSMTPDIYFDNFIICSEKEVADQWAT 441
Query: 723 ETWVVKKDAERRADPNSQSVVDAIREATSERP 818
+ W +K A+ N V+ + A ERP
Sbjct: 442 DGWELKIMV---ANANEPGVLRQLVIAAEERP 470
>sp|O14967|CLGN_HUMAN Calmegin precursor
Length = 610
Score = 333 bits (854), Expect = 4e-91
Identities = 145/243 (59%), Positives = 181/243 (74%)
Frame = +3
Query: 3 IYEEKHAKKSSSDLDRHFTDKKTHLYTLVVNSDNTFEIFVDQTLVNSGSLLKDFEPSVNP 182
++EEKHAK DL + FTD+KTHLYTLV+N D+TFE+ VDQT+VN GSLL+D P + P
Sbjct: 204 VFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFEVLVDQTVVNKGSLLEDVVPPIKP 263
Query: 183 PKEIDDPNDVKPEDWDDTPKISDPDAVKPGDWDDSAPEYIEDEKAVKPDGWLENEPLTVP 362
PKEI+DPND KPE+WD+ KI DP AVKP DWD+S P IED VKP GWL++EP +P
Sbjct: 264 PKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEPAQIEDSSVVKPAGWLDDEPKFIP 323
Query: 363 DEKSEKPKDWDDEMDGEWEAPRIDNPLCKDAPGCGPWKSPKIKNPNYKGVWTAPMIDNPK 542
D +EKP DW+++ DGEWEAP+I NP C+ GCG WK P I NP YKGVW P++DNP
Sbjct: 324 DPNAEKPDDWNEDTDGEWEAPQILNPACR--IGCGEWKPPMIDNPKYKGVWRPPLVDNPN 381
Query: 543 YKGVWKARRIPNADYFEDAQPYKMTPIGAIGLELWSMSDEIVFDNFIIVDNKKAADDFAA 722
Y+G+W R+IPN DYFED P+ +T A+GLELWSM+ +I FDNFII K+ AD +AA
Sbjct: 382 YQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMTSDIYFDNFIICSEKEVADHWAA 441
Query: 723 ETW 731
+ W
Sbjct: 442 DGW 444
>sp|Q38798|CALX2_ARATH Calnexin homolog 2 precursor
Length = 532
Score = 281 bits (720), Expect = 1e-75
Identities = 133/274 (48%), Positives = 176/274 (64%), Gaps = 13/274 (4%)
Frame = +3
Query: 15 KHAKKSSSDLDRHFT--------DKKTHLYTLVVNSDNTFEIFVDQTLVNSGSLL--KDF 164
KH S + H D +H+YT V+ SDN I VD G+LL +DF
Sbjct: 156 KHKNPKSGEFVEHHLKFPPSVPFDMLSHVYTAVLKSDNEVRILVDGEEKKKGNLLSAEDF 215
Query: 165 EPSVNPPKEIDDPNDVKPEDWDDTPKISDPDAVKPGDWDDSAPEYIEDEKAVKPDGWLEN 344
EP + P K I DP D KPEDWD+ KI DP+AVKP DWD+ AP IEDE+A KP+GWL++
Sbjct: 216 EPPLIPSKTIPDPEDKKPEDWDERAKIPDPNAVKPDDWDEDAPMEIEDEEAEKPEGWLDD 275
Query: 345 EPLTVPDEKSEKPKDWDDEMDGEWEAPRIDNPLCKDAPGCGPWKSPKIKNPNYKGVWTAP 524
EP+ V D ++ KP+DWDDE DGEWEAP++ N C+ APGCG WK P +NP YKG W++P
Sbjct: 276 EPVEVEDPEASKPEDWDDEEDGEWEAPKVSNTKCEAAPGCGEWKRPMKRNPAYKGKWSSP 335
Query: 525 MIDNPKYKGVWKARRIPNADYFEDAQPYKMTPIGAIGLELWSMSDEIVFDNFIIVDNKKA 704
+IDNP YKG+WK R IPN DYFE +P + PI AIG+E+W+M D I+FDN +I ++K
Sbjct: 336 LIDNPAYKGIWKPRDIPNPDYFELERP-NLEPIAAIGIEIWTMQDGILFDNILISKDEKV 394
Query: 705 ADDFAAETWVVKKDAER---RADPNSQSVVDAIR 797
A+ + TW K D E+ +A+ + D ++
Sbjct: 395 AETYRQSTWKPKFDVEKEKQKAEDEAAGEADGLK 428
>sp|P29402|CALX1_ARATH Calnexin homolog 1 precursor
Length = 530
Score = 279 bits (713), Expect = 8e-75
Identities = 129/251 (51%), Positives = 170/251 (67%), Gaps = 5/251 (1%)
Frame = +3
Query: 60 DKKTHLYTLVVNSDNTFEIFVDQTLVNSGSLL--KDFEPSVNPPKEIDDPNDVKPEDWDD 233
DK +H+YT ++ DN I VD +LL +DFEP++ P K I DP D KPEDWD+
Sbjct: 177 DKLSHVYTAILKPDNEVRILVDGEEKKKANLLSGEDFEPALIPAKTIPDPEDKKPEDWDE 236
Query: 234 TPKISDPDAVKPGDWDDSAPEYIEDEKAVKPDGWLENEPLTVPDEKSEKPKDWDDEMDGE 413
KI DP+AVKP DWD+ AP IEDE+A KP+GWL++EP V D ++ KP+DWDDE DG
Sbjct: 237 RAKIPDPNAVKPEDWDEDAPMEIEDEEAEKPEGWLDDEPEEVDDPEATKPEDWDDEEDGM 296
Query: 414 WEAPRIDNPLCKDAPGCGPWKSPKIKNPNYKGVWTAPMIDNPKYKGVWKARRIPNADYFE 593
WEAP+IDNP C+ APGCG WK P +NP YKG W++P+IDNP YKG+WK R IPN DYFE
Sbjct: 297 WEAPKIDNPKCEAAPGCGEWKRPMKRNPAYKGKWSSPLIDNPAYKGIWKPRDIPNPDYFE 356
Query: 594 DAQPYKMTPIGAIGLELWSMSDEIVFDNFIIVDNKKAADDFAAETWVVKKDAER---RAD 764
+P PI AIG+E+W+M D I+FDN +I ++K A+ + TW K D E+ +A+
Sbjct: 357 LDRP-DYEPIAAIGIEIWTMQDGILFDNILIAKDEKVAETYRQTTWKPKFDVEKEKQKAE 415
Query: 765 PNSQSVVDAIR 797
+ D ++
Sbjct: 416 EEAAGSADGLK 426
>sp|Q39817|CALX_SOYBN Calnexin homolog precursor
Length = 546
Score = 277 bits (708), Expect = 3e-74
Identities = 128/257 (49%), Positives = 167/257 (64%), Gaps = 10/257 (3%)
Frame = +3
Query: 15 KHAKKSSSDLDRHF--------TDKKTHLYTLVVNSDNTFEIFVDQTLVNSGSLL--KDF 164
KH S + H +DK TH+YT ++ DN +I +D + L +DF
Sbjct: 163 KHKNPKSGEYVEHHLKYPPSVPSDKLTHVYTAILKPDNELQILIDGEEKKKANFLSSEDF 222
Query: 165 EPSVNPPKEIDDPNDVKPEDWDDTPKISDPDAVKPGDWDDSAPEYIEDEKAVKPDGWLEN 344
EP + P K I DP+D KPEDWD+ KI DP AVKP DWD+ AP I DE+A KP+GWL++
Sbjct: 223 EPPLIPSKTIPDPDDKKPEDWDERAKIPDPSAVKPDDWDEDAPMEILDEEAEKPEGWLDD 282
Query: 345 EPLTVPDEKSEKPKDWDDEMDGEWEAPRIDNPLCKDAPGCGPWKSPKIKNPNYKGVWTAP 524
EP + D ++ KP+DWDDE DGEWEAP+I+NP C+ APGCG WK P +NP YKG W+AP
Sbjct: 283 EPEEIDDPEATKPEDWDDEEDGEWEAPKIENPKCEAAPGCGEWKRPTKRNPAYKGKWSAP 342
Query: 525 MIDNPKYKGVWKARRIPNADYFEDAQPYKMTPIGAIGLELWSMSDEIVFDNFIIVDNKKA 704
IDNP YKG+WK R IPN +YFE A+P PI AIG+E+W+M D I+FDN +I ++ K
Sbjct: 343 YIDNPSYKGIWKpreIPNPEYFELAKP-DFEPIAAIGIEIWTMQDGILFDNVLIANDDKV 401
Query: 705 ADDFAAETWVVKKDAER 755
A+ + TW K E+
Sbjct: 402 AESYRETTWKPKFTVEK 418
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,995,767
Number of Sequences: 369166
Number of extensions: 2258630
Number of successful extensions: 7256
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6251
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6615
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8438301375
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)