Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_J19
(719 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O01393|UNC9_CAEEL Innexin unc-9 (Uncoordinated protein 9) 150 4e-36
sp|Q03412|UNC7_CAEEL Innexin unc-7 (Uncoordinated protein 7) 137 3e-32
sp|Q23157|INX11_CAEEL Innexin-11 121 2e-27
sp|Q22549|INX10_CAEEL Innexin-10 119 8e-27
sp|Q23027|INX5_CAEEL Innexin-5 118 2e-26
sp|Q19746|INX3_CAEEL Innexin-3 117 2e-26
sp|O01634|INX12_CAEEL Innexin-12 112 8e-25
sp|O61788|INX17_CAEEL Innexin-17 (Gap junction innexin) 105 1e-22
sp|Q27295|EAT5_CAEEL Innexin eat-5 101 2e-21
sp|Q21123|INX7_CAEEL Innexin-7 97 6e-20
>sp|O01393|UNC9_CAEEL Innexin unc-9 (Uncoordinated protein 9)
Length = 386
Score = 150 bits (378), Expect = 4e-36
Identities = 70/171 (40%), Positives = 112/171 (65%)
Frame = +1
Query: 1 INVIGQLYLMKSFLGFDSSITYFGYTVLENMLNGREWHQTGIFPRVSYCYNADIRHLGST 180
+N++GQ++L+ +FLG S ++G VL +++NGREW ++G FPRV+ C + +++ LG+
Sbjct: 208 VNIVGQIFLLNTFLGNRSK--WYGLQVLNDLMNGREWEESGHFPRVTLC-DFEVKVLGNV 264
Query: 181 NTYVSQCTLPINMLNEKIYVFLWFWILLVGIITLISIFLWLIRMVFLSKRSDFIKKLLKM 360
+ + QC L INM NEKI++FLWFW L+ TL S+F W+ V S++ +F+ K L
Sbjct: 265 HRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTG 324
Query: 361 HQSYKRTDQLLVNQFIKEYLRHDGVFLIRMIYINAGDIVTAEILGTLWEIY 513
+ YK D + +F+ +LR DGVFL+RM+ +AG++ E+ TLW Y
Sbjct: 325 IEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNY 375
>sp|Q03412|UNC7_CAEEL Innexin unc-7 (Uncoordinated protein 7)
Length = 522
Score = 137 bits (345), Expect = 3e-32
Identities = 64/171 (37%), Positives = 113/171 (66%), Gaps = 3/171 (1%)
Frame = +1
Query: 4 NVIGQLYLMKSFLGFDSSITYFGYTVLENMLNGREWHQTGIFPRVSYCYNADIRHLGSTN 183
NV+ Q +L+ LG S+ +G+++L+++++ EW QTG+FPRV+ C + ++R LG+ +
Sbjct: 332 NVLLQFFLLNHLLG--SNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLC-DFEVRVLGNIH 388
Query: 184 TYVSQCTLPINMLNEKIYVFLWFWILLVGIITLISIFLWLIRMVFLSKRSDFIKKLLKM- 360
+ QC L INM NEKI++FLWFW L GI+T+ + W++ M S+ F++K L++
Sbjct: 389 RHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVL 448
Query: 361 --HQSYKRTDQLLVNQFIKEYLRHDGVFLIRMIYINAGDIVTAEILGTLWE 507
H + D + + +F +LR DGVF++RMI +AG+++++E++ LW+
Sbjct: 449 PDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQ 499
>sp|Q23157|INX11_CAEEL Innexin-11
Length = 465
Score = 121 bits (303), Expect = 2e-27
Identities = 61/177 (34%), Positives = 105/177 (59%), Gaps = 6/177 (3%)
Frame = +1
Query: 1 INVIGQLYLMKSFLGFDSSITYFGYTVLENMLNGREWHQTGIFPRVSYCYNADIRHLGST 180
+NV QLYLM FLG + ++G+ V+++++ G W ++G FPR + C + ++R + +
Sbjct: 211 LNVFAQLYLMNYFLGTNRH-HWYGFGVVQDIVQGEPWERSGYFPRAAVC-DFEVRQVANI 268
Query: 181 NTYVSQCTLPINMLNEKIYVFLWFWILLVGIITLISIFLWLIRMVFLSKRSDFIKK---- 348
Y QC L IN+ NEKI+V LWFW +++ + + +S+ W I +VF F+K+
Sbjct: 269 QRYSVQCVLVINIFNEKIFVLLWFWYVILLLSSTVSLVQWFIVLVFPCFSKWFVKQHLAL 328
Query: 349 --LLKMHQSYKRTDQLLVNQFIKEYLRHDGVFLIRMIYINAGDIVTAEILGTLWEIY 513
L +Q R + V++F+ +YL DGVF++RM+ +AG I +++ L+E Y
Sbjct: 329 STLQNFNQRNSRREDSDVSKFVTQYLHKDGVFVLRMVSSHAGIIFATDLVQALYEAY 385
>sp|Q22549|INX10_CAEEL Innexin-10
Length = 559
Score = 119 bits (298), Expect = 8e-27
Identities = 67/171 (39%), Positives = 98/171 (57%), Gaps = 4/171 (2%)
Frame = +1
Query: 4 NVIGQLYLMKSFLGFDSSITYFGYTVLENMLNGREWHQTGIFPRVSYCYNADIRHLGSTN 183
NV QL M FL D ++G L ++LNG W Q+G+FPRVS C + D+R +G+
Sbjct: 209 NVCLQLMFMNRFLETDK-YKWYGMGALVDLLNGTTWEQSGMFPRVSLC-DFDVRVMGNMQ 266
Query: 184 TYVSQCTLPINMLNEKIYVFLWFWILLVGIITLISIFLWLIRMVFLSKRSDFIKKLLKM- 360
+ QC L IN+ NEKI++ LWFW L + + T S F WL+ ++ FI + L+M
Sbjct: 267 EHTIQCVLVINIFNEKIFILLWFWYLALLVFTFGSFFYWLLVSLWRHLNVRFIIRHLEMS 326
Query: 361 ---HQSYKRTDQLLVNQFIKEYLRHDGVFLIRMIYINAGDIVTAEILGTLW 504
S + Q VN+FI YL+ DGVF+IRM+ + +G I +++ LW
Sbjct: 327 DIAFDSSEDGAQEKVNRFISNYLKSDGVFVIRMMTLQSGVIFGTDLVQELW 377
>sp|Q23027|INX5_CAEEL Innexin-5
Length = 447
Score = 118 bits (295), Expect = 2e-26
Identities = 59/176 (33%), Positives = 104/176 (59%), Gaps = 3/176 (1%)
Frame = +1
Query: 4 NVIGQLYLMKSFLGFDSSITYFGYTVLENMLNGREWHQTGIFPRVSYCYNADIRHLGSTN 183
N++ Q +++ FL ++ +G+ ++++ GREW TGIFPRV+ C + I L S +
Sbjct: 210 NIVLQFWILTYFL--ETKSWMWGWQTFQDLMAGREWETTGIFPRVTMC-DFSIMDLTSVH 266
Query: 184 TYVSQCTLPINMLNEKIYVFLWFWILLVGIITLISIFLWLIRMVFLSKRSDFIKKLLKM- 360
+ QC + INML EK+YVF WFW+L VG++T+ S+ W + + S +FI L+
Sbjct: 267 DHSIQCVIVINMLAEKVYVFFWFWLLFVGLLTVCSLAYWAVIYMLQSVGRNFIYSYLQQT 326
Query: 361 --HQSYKRTDQLLVNQFIKEYLRHDGVFLIRMIYINAGDIVTAEILGTLWEIYKEK 522
Q+ + + F+ + L DGVF+ R++ N+GD+ T+ +LG ++ +Y+ +
Sbjct: 327 PEFQTEQERGSFVPANFVDKCLTPDGVFISRLVQQNSGDLFTSIMLGEMFSLYRAR 382
>sp|Q19746|INX3_CAEEL Innexin-3
Length = 420
Score = 117 bits (294), Expect = 2e-26
Identities = 62/172 (36%), Positives = 100/172 (58%)
Frame = +1
Query: 4 NVIGQLYLMKSFLGFDSSITYFGYTVLENMLNGREWHQTGIFPRVSYCYNADIRHLGSTN 183
NV Q ++ FLG ++ + +G+ ++ GREW +G+FPRV+ C + +R L + +
Sbjct: 205 NVFVQFIILNKFLGNETFL--WGFHTFADLYAGREWQDSGVFPRVTLC-DFSVRKLANVH 261
Query: 184 TYVSQCTLPINMLNEKIYVFLWFWILLVGIITLISIFLWLIRMVFLSKRSDFIKKLLKMH 363
Y QC L INM NEKIY+F+WFW + V I T I+ + R+ F S R ++I+ LL
Sbjct: 262 RYTVQCVLMINMFNEKIYLFIWFWFVFVLITTFINTLCTIYRLSFDSSRHNYIRSLLSGP 321
Query: 364 QSYKRTDQLLVNQFIKEYLRHDGVFLIRMIYINAGDIVTAEILGTLWEIYKE 519
+ + ++ ++ F L+ DGV L+R I +AG +VT EI L++ + E
Sbjct: 322 VNNFKDEKAMIASFANNGLKQDGVLLMRFIDDHAGAMVTKEICEELFKKHGE 373
>sp|O01634|INX12_CAEEL Innexin-12
Length = 408
Score = 112 bits (281), Expect = 8e-25
Identities = 57/168 (33%), Positives = 97/168 (57%)
Frame = +1
Query: 1 INVIGQLYLMKSFLGFDSSITYFGYTVLENMLNGREWHQTGIFPRVSYCYNADIRHLGST 180
INV+ Q L+K LG DS ++G V ++ +G EW +TG FPRV+ C ++R+L +
Sbjct: 210 INVLFQFVLLKRMLGVDSY--FWGAEVTSDLWSGNEWPETGNFPRVTMC-EYEVRNLDNI 266
Query: 181 NTYVSQCTLPINMLNEKIYVFLWFWILLVGIITLISIFLWLIRMVFLSKRSDFIKKLLKM 360
+ + QC L INM NEKI+V LW+W+ + ++T+ + W R S +FI+ ++
Sbjct: 267 HKHSVQCVLMINMFNEKIFVALWWWLCFLTVVTITNTIYWFWRASGTSVSKNFIRPYVED 326
Query: 361 HQSYKRTDQLLVNQFIKEYLRHDGVFLIRMIYINAGDIVTAEILGTLW 504
+ ++ + QF+ E+L D VF++R+I +N G E++ +W
Sbjct: 327 IDPKVKNNRGKLQQFVSEFLSPDTVFILRLIELNNGKTPVVELIRDMW 374
>sp|O61788|INX17_CAEEL Innexin-17 (Gap junction innexin)
Length = 362
Score = 105 bits (262), Expect = 1e-22
Identities = 54/170 (31%), Positives = 98/170 (57%), Gaps = 3/170 (1%)
Frame = +1
Query: 19 LYLMKSFLGFDSSI-TYFGYTVLENMLNGREWHQTGIFPRVSYCYNADIRHLGSTNTYVS 195
+++ FL + + +G+T+ +++L GR+W ++G FPRV++C + +R LG N +
Sbjct: 195 IFISMGFLDYFMGLGPMYGWTITKDILQGRQWQESGSFPRVTFC-DFQVRELGYVNNWSL 253
Query: 196 QCTLPINMLNEKIYVFLWFWILLVGIITLISIFLWLIRMVFLSKRSDFIKKLLKM--HQS 369
QC L +NM NEK+++ LW+W L+ I+++ IF L R + + FI ++L +
Sbjct: 254 QCVLMVNMFNEKLFIALWWWYALLAILSIFDIFRVLFRFT-IHHQISFITRILACTGDSA 312
Query: 370 YKRTDQLLVNQFIKEYLRHDGVFLIRMIYINAGDIVTAEILGTLWEIYKE 519
T+ V +F ++ LR DG+ L ++Y NA A+ + +WE +KE
Sbjct: 313 ISATE---VGEFNRKVLRIDGINLTHLVYANATIFEAADFVRPMWEQFKE 359
>sp|Q27295|EAT5_CAEEL Innexin eat-5
Length = 423
Score = 101 bits (251), Expect = 2e-21
Identities = 57/183 (31%), Positives = 91/183 (49%), Gaps = 14/183 (7%)
Frame = +1
Query: 16 QLYLMKSFLGFDSSITYFGYTVLENMLNGREWHQTGIFPRVSYCYNADIRHLGSTNTYVS 195
Q Y FLG + Y+G +L+++L G +W +G FPR++ C + +R LG+ Y
Sbjct: 208 QFYSTNKFLGQNDP--YWGMRILDDILKGTDWEHSGNFPRIAMC-DFQVRVLGNLQRYSI 264
Query: 196 QCTLPINMLNEKIYVFLWFWILLVGIITLISIFLWLIRMVFLSKRSDFIKKLLKMHQS-- 369
QC L +NM NEKI++FL+ W LLV +TL M K +F+++ L
Sbjct: 265 QCVLTLNMFNEKIFLFLYIWFLLVFFVTLFDSIFLCYNMFSSHKLVEFLQQFLDNQDQDE 324
Query: 370 ------------YKRTDQLLVNQFIKEYLRHDGVFLIRMIYINAGDIVTAEILGTLWEIY 513
K +L+++F D + L++MI + GDIV EI+G +W +
Sbjct: 325 NDEKKPEERKVYRKEQHSILLSEFCLHKFTPDIIILLKMINNHTGDIVCTEIVGRMWNEF 384
Query: 514 KEK 522
E+
Sbjct: 385 LER 387
>sp|Q21123|INX7_CAEEL Innexin-7
Length = 556
Score = 96.7 bits (239), Expect = 6e-20
Identities = 59/182 (32%), Positives = 97/182 (53%), Gaps = 9/182 (4%)
Frame = +1
Query: 1 INVIGQLYLMKSFLGFDSSITYFGY----TVLENMLNGRE-WHQTGIFPRVSYCYNADIR 165
+NVI Q L+ ++ FG+ T+ NG E W + G+FPRV+ C + + R
Sbjct: 229 LNVILQSKLLNKYMLPHDRQQNFGFDMWKTIFYGSTNGNETWRENGVFPRVTLC-DFETR 287
Query: 166 HLGSTNTYVSQCTLPINMLNEKIYVFLWFWILLVGIITLISIFLWLIRMVFLSKRSDFIK 345
+G+ + QC L +N+ EKI+VFLW W +L+ T+ ++F WL + + FI
Sbjct: 288 DMGNVQMHTVQCVLLLNLFTEKIFVFLWAWYILLTAFTVGNLFSWLFAVFNETYNEHFIL 347
Query: 346 KLLKMHQSYKRTDQLL----VNQFIKEYLRHDGVFLIRMIYINAGDIVTAEILGTLWEIY 513
L+M ++ D L V +FI YL DG+FL+++I +A + T E++ L++ Y
Sbjct: 348 NHLEMCETPFDKDDLKNREHVTRFITLYLGTDGLFLLQLIAQHADVVFTTELIAALFKTY 407
Query: 514 KE 519
E
Sbjct: 408 IE 409
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,438,306
Number of Sequences: 369166
Number of extensions: 1400802
Number of successful extensions: 3615
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3498
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3581
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6413660220
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)