Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_003_J05 (372 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P59999|ARPC4_MOUSE Actin-related protein 2/3 complex sub... 153 1e-37 sp|P58798|ARPC4_CAEEL Probable actin-related protein 2/3 co... 140 7e-34 sp|Q92352|ARPC4_SCHPO Probable ARP2/3 complex 20 kDa subuni... 129 2e-30 sp|P33204|ARPC4_YEAST ARP2/3 complex 20 kDa subunit (p20-ARC) 120 7e-28 sp|P09838|TDT_MOUSE DNA nucleotidylexotransferase (Terminal... 30 2.3 sp|O55111|DSG2_MOUSE Desmoglein-2 precursor 29 2.9 sp|P25655|NOT1_YEAST General negative regulator of transcri... 29 2.9 sp|O75691|DRIM_HUMAN Down-regulated in metastasis protein (... 28 6.6
>sp|P59999|ARPC4_MOUSE Actin-related protein 2/3 complex subunit 4 (ARP2/3 complex 20 kDa subunit) (p20-ARC) sp|P59998|ARPC4_HUMAN Actin-related protein 2/3 complex subunit 4 (ARP2/3 complex 20 kDa subunit) (p20-ARC) Length = 168 Score = 153 bits (386), Expect = 1e-37 Identities = 75/91 (82%), Positives = 82/91 (90%) Frame = +2 Query: 2 QSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIG 181 Q+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I Sbjct: 78 QADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIH 137 Query: 182 FMEDIDKEISEMRLAVNARARQCAEEFLKAF 274 FME+IDKEISEM+L+VNARAR AEEFLK F Sbjct: 138 FMEEIDKEISEMKLSVNARARIVAEEFLKNF 168
>sp|P58798|ARPC4_CAEEL Probable actin-related protein 2/3 complex subunit 4 (ARP2/3 complex 20 kDa subunit) (p20-ARC) Length = 169 Score = 140 bits (354), Expect = 7e-34 Identities = 67/92 (72%), Positives = 79/92 (85%) Frame = +2 Query: 2 QSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIG 181 QSDEIEK+LCHKFTRFM RA+ F +LRRKP+ GYDISFLIT HTE M KHKLVDF++ Sbjct: 78 QSDEIEKILCHKFTRFMCQRADNFFVLRRKPLPGYDISFLITASHTEAMFKHKLVDFLLH 137 Query: 182 FMEDIDKEISEMRLAVNARARQCAEEFLKAFD 277 FM++IDKEISEM+L++NARAR AEEFLK F+ Sbjct: 138 FMQEIDKEISEMKLSLNARARVSAEEFLKRFN 169
>sp|Q92352|ARPC4_SCHPO Probable ARP2/3 complex 20 kDa subunit (p20-ARC) Length = 168 Score = 129 bits (325), Expect = 2e-30 Identities = 64/91 (70%), Positives = 74/91 (81%) Frame = +2 Query: 2 QSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIG 181 Q DEIE++L KF +F+M RAE F ILRRKPVQGYDISFLITN HTE+MLKHKLVDFII Sbjct: 78 QVDEIERILVRKFMQFLMGRAESFFILRRKPVQGYDISFLITNYHTEEMLKHKLVDFIIE 137 Query: 182 FMEDIDKEISEMRLAVNARARQCAEEFLKAF 274 FME++D EISEM+L +N RAR AE +L F Sbjct: 138 FMEEVDAEISEMKLFLNGRARLVAETYLSCF 168
>sp|P33204|ARPC4_YEAST ARP2/3 complex 20 kDa subunit (p20-ARC) Length = 171 Score = 120 bits (302), Expect = 7e-28 Identities = 61/91 (67%), Positives = 71/91 (78%) Frame = +2 Query: 2 QSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIG 181 Q+DEIE++L HKFTRF+ RAE F ILRR P+ GY ISFLITN HTE M KLVDFII Sbjct: 79 QADEIEQILVHKFTRFLEQRAEAFYILRRVPIPGYSISFLITNKHTESMKTGKLVDFIIE 138 Query: 182 FMEDIDKEISEMRLAVNARARQCAEEFLKAF 274 FMED+DKEISE++L +NARAR AE +L F Sbjct: 139 FMEDVDKEISEIKLFLNARARFVAEAYLDEF 169
>sp|P09838|TDT_MOUSE DNA nucleotidylexotransferase (Terminal addition enzyme) (Terminal deoxynucleotidyltransferase) (TDT) (Terminal transferase) Length = 530 Score = 29.6 bits (65), Expect = 2.3 Identities = 15/34 (44%), Positives = 20/34 (58%), Gaps = 4/34 (11%) Frame = +2 Query: 83 RRKPVQGYDISFLITNVHT----EQMLKHKLVDF 172 RR + G+D+ FLIT+ EQ L HK+ DF Sbjct: 335 RRGKMTGHDVDFLITSPEATEDEEQQLLHKVTDF 368
>sp|O55111|DSG2_MOUSE Desmoglein-2 precursor Length = 1122 Score = 29.3 bits (64), Expect = 2.9 Identities = 13/23 (56%), Positives = 16/23 (69%) Frame = -2 Query: 371 LAKINSKLLENKSINLLYKVTGK 303 +AKI+S L E K I + YK TGK Sbjct: 75 IAKIHSDLAEEKGIKITYKYTGK 97
>sp|P25655|NOT1_YEAST General negative regulator of transcription subunit 1 Length = 2108 Score = 29.3 bits (64), Expect = 2.9 Identities = 16/50 (32%), Positives = 31/50 (62%) Frame = -2 Query: 371 LAKINSKLLENKSINLLYKVTGKISIIINIPNRMPSGIPQHIVELEHSLP 222 L + SK + +++++YK G + +I+ I N MPS + ++ EL ++LP Sbjct: 1789 LDQYTSKHAVSDAVSVVYK--GTLRVILGISNDMPSFLIENHYELMNNLP 1836
>sp|O75691|DRIM_HUMAN Down-regulated in metastasis protein (Key-1A6 protein) (Novel nucleolar protein 73) (NNP73) Length = 2785 Score = 28.1 bits (61), Expect = 6.6 Identities = 14/55 (25%), Positives = 30/55 (54%), Gaps = 4/55 (7%) Frame = +2 Query: 8 DEIEKLLCHKFTRFMMMRAEEF----VILRRKPVQGYDISFLITNVHTEQMLKHK 160 + ++ + H+ R + A++ V+L K +Q Y + + +T + E+MLKH+ Sbjct: 1576 ENMKHIQIHRRARALKKLAKQLMEGKVVLSSKSLQNYIMPYAMTPIFDEKMLKHE 1630
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 37,064,281 Number of Sequences: 369166 Number of extensions: 626179 Number of successful extensions: 1580 Number of sequences better than 10.0: 8 Number of HSP's better than 10.0 without gapping: 1564 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1580 length of database: 68,354,980 effective HSP length: 90 effective length of database: 51,728,830 effective search space used: 1707051390 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)