Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_J01
(422 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P55809|SCOT_HUMAN Succinyl-CoA:3-ketoacid-coenzyme A tra... 182 3e-46
sp|Q9BYC2|SCOT2_HUMAN Succinyl-CoA:3-ketoacid-coenzyme A tr... 178 4e-45
sp|Q29551|SCOT_PIG Succinyl-CoA:3-ketoacid-coenzyme A trans... 178 4e-45
sp|Q9D0K2|SCOT_MOUSE Succinyl-CoA:3-ketoacid-coenzyme A tra... 178 5e-45
sp|Q09450|SCOT_CAEEL Probable succinyl-CoA:3-ketoacid-coenz... 156 2e-38
sp|O34264|SCOA_XANCP Succinyl-CoA:3-ketoacid-coenzyme A tra... 132 4e-31
sp|P42315|SCOA_BACSU Probable succinyl-CoA:3-ketoacid-coenz... 130 1e-30
sp|Q9ZLE3|SCOA_HELPJ Succinyl-CoA:3-ketoacid-coenzyme A tra... 128 4e-30
sp|P63649|SCOA_MYCBO Probable succinyl-CoA:3-ketoacid-coenz... 126 2e-29
sp|P56006|SCOA_HELPY Succinyl-CoA:3-ketoacid-coenzyme A tra... 126 2e-29
>sp|P55809|SCOT_HUMAN Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial
precursor (Somatic-type succinyl CoA:3-oxoacid
CoA-transferase) (Scot-S)
Length = 520
Score = 182 bits (462), Expect = 3e-46
Identities = 85/139 (61%), Positives = 107/139 (76%)
Frame = +2
Query: 5 PQGTLAERIRAGGAGIPAFYTPTAYGTLIQLGGTPIKYDSKGQVLLTSEPKEDRLINGRN 184
PQGTLAERIRAGGAG+PAFYTPT YGTL+Q GG+PIKY+ G V + S+P+E R NG++
Sbjct: 137 PQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSVAIASKpreVREFNGQH 196
Query: 185 YVMETAIRGNFALIKAWKADKAGNVIFRKTARNFNETMCRAADTTXXXXXXXXXXXXXDP 364
+++E AI G+FAL+KAWKAD+AGNVIFRK+ARNFN MC+AA+TT P
Sbjct: 197 FILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAP 256
Query: 365 DHIHVPGIYVDRVLLGEKY 421
+ IH+P IYV R++ GEKY
Sbjct: 257 EDIHIPQIYVHRLIKGEKY 275
>sp|Q9BYC2|SCOT2_HUMAN Succinyl-CoA:3-ketoacid-coenzyme A transferase 2, mitochondrial
precursor (Testis-specific succinyl CoA:3-oxoacid
CoA-transferase) (SCOT-t)
Length = 517
Score = 178 bits (452), Expect = 4e-45
Identities = 83/139 (59%), Positives = 103/139 (74%)
Frame = +2
Query: 5 PQGTLAERIRAGGAGIPAFYTPTAYGTLIQLGGTPIKYDSKGQVLLTSEPKEDRLINGRN 184
PQGTLAERIRAGGAG+PAFYTPT YGTL+Q GG PI+Y G + L S+P+E R NG +
Sbjct: 137 PQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGAPIRYTPDGHLALMSQpreVREFNGDH 196
Query: 185 YVMETAIRGNFALIKAWKADKAGNVIFRKTARNFNETMCRAADTTXXXXXXXXXXXXXDP 364
+++E AIR +FAL+K WKAD+AGNV+FR++ARNFN MC+AAD T P
Sbjct: 197 FLLERAIRADFALVKGWKADRAGNVVFRRSARNFNVPMCKAADVTAVEVEEIVEVGAFPP 256
Query: 365 DHIHVPGIYVDRVLLGEKY 421
+ IHVP IYVDRV+ G+KY
Sbjct: 257 EDIHVPNIYVDRVIKGQKY 275
>sp|Q29551|SCOT_PIG Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial
precursor (Somatic-type succinyl CoA:3-oxoacid
CoA-transferase) (Scot-S)
Length = 520
Score = 178 bits (452), Expect = 4e-45
Identities = 83/139 (59%), Positives = 106/139 (76%)
Frame = +2
Query: 5 PQGTLAERIRAGGAGIPAFYTPTAYGTLIQLGGTPIKYDSKGQVLLTSEPKEDRLINGRN 184
PQGTLAERIRAGGAG+PAFYT T YGTL+Q GG+PIKY+ G + + S+P+E R NG++
Sbjct: 137 PQGTLAERIRAGGAGVPAFYTSTGYGTLVQEGGSPIKYNKDGSIAIASKpreVREFNGQH 196
Query: 185 YVMETAIRGNFALIKAWKADKAGNVIFRKTARNFNETMCRAADTTXXXXXXXXXXXXXDP 364
+++E AIRG+FAL+KAWKAD+AGNV FRK+ARNFN MC+AA+TT P
Sbjct: 197 FILEEAIRGDFALVKAWKADQAGNVTFRKSARNFNLPMCKAAETTVVEVEEIVDIGSFAP 256
Query: 365 DHIHVPGIYVDRVLLGEKY 421
+ IH+P IYV R++ GEKY
Sbjct: 257 EDIHIPKIYVHRLVKGEKY 275
>sp|Q9D0K2|SCOT_MOUSE Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial
precursor (Somatic-type succinyl CoA:3-oxoacid
CoA-transferase) (Scot-S)
Length = 520
Score = 178 bits (451), Expect = 5e-45
Identities = 84/139 (60%), Positives = 105/139 (75%)
Frame = +2
Query: 5 PQGTLAERIRAGGAGIPAFYTPTAYGTLIQLGGTPIKYDSKGQVLLTSEPKEDRLINGRN 184
PQGTLAERIRAGGAG+PAFYT T YGTL+Q GG+PIKY+ G V + S+P+E R NG++
Sbjct: 137 PQGTLAERIRAGGAGVPAFYTSTGYGTLVQEGGSPIKYNKDGSVAIASKpreVREFNGQH 196
Query: 185 YVMETAIRGNFALIKAWKADKAGNVIFRKTARNFNETMCRAADTTXXXXXXXXXXXXXDP 364
+++E AI G+FAL+KAWKAD+AGNVIFRK+ARNFN MC+AA TT P
Sbjct: 197 FILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAGTTVVEVEEIVDIGSFAP 256
Query: 365 DHIHVPGIYVDRVLLGEKY 421
+ IH+P IYV R++ GEKY
Sbjct: 257 EDIHIPKIYVHRLIKGEKY 275
>sp|Q09450|SCOT_CAEEL Probable succinyl-CoA:3-ketoacid-coenzyme A transferase,
mitochondrial precursor (3-oxoacid CoA-transferase)
Length = 521
Score = 156 bits (394), Expect = 2e-38
Identities = 78/141 (55%), Positives = 94/141 (66%), Gaps = 2/141 (1%)
Frame = +2
Query: 5 PQGTLAERIRAGGAGIPAFYTPTAYGTLIQLGGTPIKYDS--KGQVLLTSEPKEDRLING 178
PQGTLAERIRA GAG+PAFYTPT YGT IQ GG PIKY KG++ + S+ KE R NG
Sbjct: 134 PQGTLAERIRAAGAGVPAFYTPTGYGTQIQEGGAPIKYSKTEKGKIEVASKAKETRQFNG 193
Query: 179 RNYVMETAIRGNFALIKAWKADKAGNVIFRKTARNFNETMCRAADTTXXXXXXXXXXXXX 358
NYVME AI G+FALIKAW+AD GN+ FR A NFN MC+A+ T
Sbjct: 194 INYVMEEAIWGDFALIKAWRADTLGNIQFRHAAGNFNNPMCKASKCTIVEVEEIVEPGVI 253
Query: 359 DPDHIHVPGIYVDRVLLGEKY 421
P+ +H+P IY R++LG+ Y
Sbjct: 254 APNDVHIPSIYCHRLVLGKNY 274
>sp|O34264|SCOA_XANCP Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (Succinyl
CoA:3-oxoacid CoA-transferase) (OXCT A)
Length = 242
Score = 132 bits (331), Expect = 4e-31
Identities = 66/135 (48%), Positives = 84/135 (62%)
Frame = +2
Query: 5 PQGTLAERIRAGGAGIPAFYTPTAYGTLIQLGGTPIKYDSKGQVLLTSEPKEDRLINGRN 184
PQGTLAER+RAGGAGIPAFYT T YGT++ G KE R +G++
Sbjct: 108 PQGTLAERLRAGGAGIPAFYTATGYGTIVAYG------------------KETREFDGKH 149
Query: 185 YVMETAIRGNFALIKAWKADKAGNVIFRKTARNFNETMCRAADTTXXXXXXXXXXXXXDP 364
YV+ETA++ + ALIKAW+AD AGN++FRKTARNFN A DP
Sbjct: 150 YVLETALQADVALIKAWRADTAGNLVFRKTARNFNPACAMAGRVCIAEVEEIVELGAIDP 209
Query: 365 DHIHVPGIYVDRVLL 409
D +H+PGIY+DR++L
Sbjct: 210 DQVHLPGIYIDRLVL 224
>sp|P42315|SCOA_BACSU Probable succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A
(Succinyl CoA:3-oxoacid CoA-transferase) (OXCT A)
Length = 238
Score = 130 bits (326), Expect = 1e-30
Identities = 70/137 (51%), Positives = 78/137 (56%)
Frame = +2
Query: 2 VPQGTLAERIRAGGAGIPAFYTPTAYGTLIQLGGTPIKYDSKGQVLLTSEPKEDRLINGR 181
VPQGTLAERIRAGGAGIP FYT T GT I +E KE + GR
Sbjct: 98 VPQGTLAERIRAGGAGIPGFYTATGVGTSI------------------AEGKEHKTFGGR 139
Query: 182 NYVMETAIRGNFALIKAWKADKAGNVIFRKTARNFNETMCRAADTTXXXXXXXXXXXXXD 361
YV+E I G+ A++KAWKAD GN+IFRKTARNFN A T D
Sbjct: 140 TYVLERGITGDVAIVKAWKADTMGNLIFRKTARNFNPIAAMAGKITIAEAEEIVEAGELD 199
Query: 362 PDHIHVPGIYVDRVLLG 412
PDHIH PGIYV V+LG
Sbjct: 200 PDHIHTPGIYVQHVVLG 216
>sp|Q9ZLE3|SCOA_HELPJ Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (Succinyl
CoA:3-oxoacid CoA-transferase) (OXCT A)
Length = 232
Score = 128 bits (322), Expect = 4e-30
Identities = 67/139 (48%), Positives = 81/139 (58%)
Frame = +2
Query: 5 PQGTLAERIRAGGAGIPAFYTPTAYGTLIQLGGTPIKYDSKGQVLLTSEPKEDRLINGRN 184
PQGTLAE +RAGGAGIPA+YTPT GTLI G KE R NG+
Sbjct: 99 PQGTLAENLRAGGAGIPAYYTPTGVGTLIAQG------------------KESREFNGKE 140
Query: 185 YVMETAIRGNFALIKAWKADKAGNVIFRKTARNFNETMCRAADTTXXXXXXXXXXXXXDP 364
Y++E AI G++ LIKA+K+D GN++FRKTARNFN AA DP
Sbjct: 141 YILERAITGDYGLIKAYKSDTLGNLVFRKTARNFNPLCAMAAKICVAEVEEIVPAGELDP 200
Query: 365 DHIHVPGIYVDRVLLGEKY 421
D IH+PGIYV + GEK+
Sbjct: 201 DEIHLPGIYVQHIYKGEKF 219
>sp|P63649|SCOA_MYCBO Probable succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A
(Succinyl CoA:3-oxoacid CoA-transferase) (OXCT A)
sp|P63648|SCOA_MYCTU Probable succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A
(Succinyl CoA:3-oxoacid CoA-transferase) (OXCT A)
Length = 248
Score = 126 bits (317), Expect = 2e-29
Identities = 62/134 (46%), Positives = 80/134 (59%)
Frame = +2
Query: 5 PQGTLAERIRAGGAGIPAFYTPTAYGTLIQLGGTPIKYDSKGQVLLTSEPKEDRLINGRN 184
PQGTLAER+RAGG GIPAFYTP GT + GG P +YD+ G V + S KE R +G
Sbjct: 99 PQGTLAERLRAGGMGIPAFYTPAGVGTQVADGGLPWRYDASGGVAVVSPAKETREFDGVT 158
Query: 185 YVMETAIRGNFALIKAWKADKAGNVIFRKTARNFNETMCRAADTTXXXXXXXXXXXXXDP 364
YV+E IR +FAL+ AW+ D+ GN+++R A NFN A T DP
Sbjct: 159 YVLERGIRTDFALVHAWQGDRHGNLMYRHAAANFNPECASAGRITIAEVEHLVEPGEIDP 218
Query: 365 DHIHVPGIYVDRVL 406
+H PG++V RV+
Sbjct: 219 ATVHTPGVFVHRVV 232
>sp|P56006|SCOA_HELPY Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (Succinyl
CoA:3-oxoacid CoA-transferase) (OXCT A)
Length = 232
Score = 126 bits (317), Expect = 2e-29
Identities = 66/139 (47%), Positives = 80/139 (57%)
Frame = +2
Query: 5 PQGTLAERIRAGGAGIPAFYTPTAYGTLIQLGGTPIKYDSKGQVLLTSEPKEDRLINGRN 184
PQGTLAE + AGGAGIPA+YTPT GTLI G KE R NG+
Sbjct: 99 PQGTLAENLHAGGAGIPAYYTPTGVGTLIAQG------------------KESREFNGKE 140
Query: 185 YVMETAIRGNFALIKAWKADKAGNVIFRKTARNFNETMCRAADTTXXXXXXXXXXXXXDP 364
Y++E AI G++ LIKA+K+D GN++FRKTARNFN AA DP
Sbjct: 141 YILERAITGDYGLIKAYKSDTLGNLVFRKTARNFNPLCAMAAKICVAEVEEIVPAGELDP 200
Query: 365 DHIHVPGIYVDRVLLGEKY 421
D IH+PGIYV + GEK+
Sbjct: 201 DEIHLPGIYVQHIYKGEKF 219
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,501,327
Number of Sequences: 369166
Number of extensions: 870307
Number of successful extensions: 2304
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2203
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2291
length of database: 68,354,980
effective HSP length: 99
effective length of database: 50,066,215
effective search space used: 2052714815
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)