Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_I02
(858 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8BRX9|MARH3_MOUSE Membrane-associated RING finger prote... 85 3e-16
sp|Q86UD3|MARH3_HUMAN Membrane-associated RING finger prote... 85 3e-16
sp|Q5XIE5|MARH3_RAT Membrane-associated RING finger protein... 85 3e-16
sp|Q99M02|MARH2_MOUSE Membrane-associated RING finger prote... 81 4e-15
sp|Q9P0N8|MARH2_HUMAN Membrane-associated RING finger prote... 80 6e-15
sp|P90489|MIR2_HHV8 Modulator of immune recognition 2 (MIR2... 54 7e-07
sp|Q9P2E8|MARH4_HUMAN Membrane-associated RING finger prote... 53 1e-06
sp|Q80TE3|MARH4_MOUSE Membrane-associated RING finger prote... 53 1e-06
sp|P40318|SSM4_YEAST Protein SSM4 47 5e-05
sp|P32225|VC07_SWPVK Hypothetical protein C7 46 2e-04
>sp|Q8BRX9|MARH3_MOUSE Membrane-associated RING finger protein 3 (Membrane-associated
RING-CH protein III) (MARCH-III)
Length = 218
Score = 84.7 bits (208), Expect = 3e-16
Identities = 35/102 (34%), Positives = 59/102 (57%), Gaps = 3/102 (2%)
Frame = -2
Query: 494 CRICLDNDKENEKLMSPCRCKGTVGLMHSTCLQQWIKISGKEQCEICKCNYDMRKRRADL 315
CRIC + + E L+SPC C GT+G +H +CL+ W+ S CE+C + + ++ L
Sbjct: 71 CRICHEGSSQ-EDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPL 129
Query: 314 NMWIKH---LFRQKTFIGDLFCFLFLVPCTTIAVFFCFKAAM 198
W+++ ++T GD+ CFLF+ P TI+ + C + A+
Sbjct: 130 VEWLRNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAV 171
>sp|Q86UD3|MARH3_HUMAN Membrane-associated RING finger protein 3 (Membrane-associated
RING-CH protein III) (MARCH-III) (RING finger protein
173)
Length = 253
Score = 84.7 bits (208), Expect = 3e-16
Identities = 35/102 (34%), Positives = 59/102 (57%), Gaps = 3/102 (2%)
Frame = -2
Query: 494 CRICLDNDKENEKLMSPCRCKGTVGLMHSTCLQQWIKISGKEQCEICKCNYDMRKRRADL 315
CRIC + + E L+SPC C GT+G +H +CL+ W+ S CE+C + + ++ L
Sbjct: 71 CRICHEGSSQ-EDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPL 129
Query: 314 NMWIKH---LFRQKTFIGDLFCFLFLVPCTTIAVFFCFKAAM 198
W+++ ++T GD+ CFLF+ P TI+ + C + A+
Sbjct: 130 VEWLRNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAV 171
>sp|Q5XIE5|MARH3_RAT Membrane-associated RING finger protein 3 (Membrane-associated
RING-CH protein III) (MARCH-III)
Length = 253
Score = 84.7 bits (208), Expect = 3e-16
Identities = 35/102 (34%), Positives = 59/102 (57%), Gaps = 3/102 (2%)
Frame = -2
Query: 494 CRICLDNDKENEKLMSPCRCKGTVGLMHSTCLQQWIKISGKEQCEICKCNYDMRKRRADL 315
CRIC + + E L+SPC C GT+G +H +CL+ W+ S CE+C + + ++ L
Sbjct: 71 CRICHEGSSQ-EDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPL 129
Query: 314 NMWIKH---LFRQKTFIGDLFCFLFLVPCTTIAVFFCFKAAM 198
W+++ ++T GD+ CFLF+ P TI+ + C + A+
Sbjct: 130 VEWLRNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAV 171
>sp|Q99M02|MARH2_MOUSE Membrane-associated RING finger protein 2 (Membrane-associated
RING-CH protein II) (MARCH-II)
Length = 246
Score = 80.9 bits (198), Expect = 4e-15
Identities = 39/116 (33%), Positives = 60/116 (51%), Gaps = 3/116 (2%)
Frame = -2
Query: 539 SNVIVGNTSRISMLKCRICLDNDKENEKLMSPCRCKGTVGLMHSTCLQQWIKISGKEQCE 360
S VI S+ CRIC + E L+SPC C GT+G +H +CL++W+ S CE
Sbjct: 49 STVIRALDSQSDCPFCRICHEG-ANGENLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCE 107
Query: 359 ICKCNYDMRKRRADLNMWIKH---LFRQKTFIGDLFCFLFLVPCTTIAVFFCFKAA 201
+C + + KR L W+K ++T D+ CF+F+ P I+ + C + A
Sbjct: 108 LCHTEFAVEKRPRPLTEWLKDPGPRTEKRTLCCDMVCFVFITPLAAISGWLCLRGA 163
>sp|Q9P0N8|MARH2_HUMAN Membrane-associated RING finger protein 2 (Membrane-associated
RING-CH protein II) (MARCH-II) (RING finger protein 172)
Length = 246
Score = 80.5 bits (197), Expect = 6e-15
Identities = 36/101 (35%), Positives = 55/101 (54%), Gaps = 3/101 (2%)
Frame = -2
Query: 494 CRICLDNDKENEKLMSPCRCKGTVGLMHSTCLQQWIKISGKEQCEICKCNYDMRKRRADL 315
CRIC + E L+SPC C GT+G +H +CL++W+ S CE+C + + KR L
Sbjct: 64 CRICHEG-ANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPRPL 122
Query: 314 NMWIKH---LFRQKTFIGDLFCFLFLVPCTTIAVFFCFKAA 201
W+K ++T D+ CFLF+ P I+ + C + A
Sbjct: 123 TEWLKDPGPRTEKRTLCCDMVCFLFITPLAAISGWLCLRGA 163
>sp|P90489|MIR2_HHV8 Modulator of immune recognition 2 (MIR2) (IE1A protein) (ORF K5)
Length = 256
Score = 53.5 bits (127), Expect = 7e-07
Identities = 31/108 (28%), Positives = 55/108 (50%), Gaps = 2/108 (1%)
Frame = -2
Query: 494 CRICLDNDKENEKLMSPCRCKGTVGLMHSTCLQQWIKISGKEQCEICKCNYDMRKR-RAD 318
C IC ++ + + PC C G + ++H CL W+ +S C++C+ Y R + R+
Sbjct: 15 CWIC--REEVGNEGIHPCACTGELDVVHPQCLSTWLTVSRNTACQMCRVIYRTRTQWRSR 72
Query: 317 LNMWIKHLFRQKTFIGDLFCFLFLVPCTTIAVFFC-FKAAMFLFSPTG 177
LN+W + RQ+ F +LF + +V + V C + + L +P G
Sbjct: 73 LNLW-PEMERQEIF--ELFLLMSVVVAGLVGVALCTWTLLVILTAPAG 117
>sp|Q9P2E8|MARH4_HUMAN Membrane-associated RING finger protein 4 (Membrane-associated
RING-CH protein IV) (MARCH-IV) (RING finger protein 174)
Length = 410
Score = 52.8 bits (125), Expect = 1e-06
Identities = 23/51 (45%), Positives = 29/51 (56%)
Frame = -2
Query: 494 CRICLDNDKENEKLMSPCRCKGTVGLMHSTCLQQWIKISGKEQCEICKCNY 342
CRIC ++ E L+SPCRC G+V H CL +WI G CE+C Y
Sbjct: 163 CRICFQGPEQGE-LLSPCRCDGSVKCTHQPCLIKWISERGCWSCELCYYKY 212
>sp|Q80TE3|MARH4_MOUSE Membrane-associated RING finger protein 4 (Membrane-associated
RING-CH protein IV) (MARCH-IV)
Length = 408
Score = 52.8 bits (125), Expect = 1e-06
Identities = 23/51 (45%), Positives = 29/51 (56%)
Frame = -2
Query: 494 CRICLDNDKENEKLMSPCRCKGTVGLMHSTCLQQWIKISGKEQCEICKCNY 342
CRIC ++ E L+SPCRC G+V H CL +WI G CE+C Y
Sbjct: 162 CRICFQGPEQGE-LLSPCRCDGSVKCTHQPCLIKWISERGCWSCELCYYKY 211
>sp|P40318|SSM4_YEAST Protein SSM4
Length = 1319
Score = 47.4 bits (111), Expect = 5e-05
Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 8/55 (14%)
Frame = -2
Query: 494 CRICLDNDKENEKLMSPCRCKGTVGLMHSTCLQQWI--------KISGKEQCEIC 354
CRIC E+ L PC+C+G++ MH +CL +W+ K +C+IC
Sbjct: 39 CRICRGEATEDNPLFHPCKCRGSIKYMHESCLLEWVASKNIDISKPGADVKCDIC 93
>sp|P32225|VC07_SWPVK Hypothetical protein C7
Length = 155
Score = 45.8 bits (107), Expect = 2e-04
Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Frame = -2
Query: 494 CRICLDNDKENEKLMSPCRCKGTVGLMHSTCLQQWIKISGKEQCEICKCNYDMRKRRADL 315
C IC D D EK + C CK ++H C+++WI+ S + C++C Y++ R
Sbjct: 5 CWICKD-DYSIEK--NYCNCKNEYKVVHDECMKKWIQYSRERSCKLCNKEYNIISVRKPF 61
Query: 314 NMW---IKHLFRQKTFIGDLFCFLFLV 243
+ W IK + LF F++
Sbjct: 62 SQWVFSIKDCKKSAILYATLFLCTFII 88
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,644,550
Number of Sequences: 369166
Number of extensions: 1927878
Number of successful extensions: 5043
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4747
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5028
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8486520240
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)