Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_F17
(606 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99087|LDLR1_XENLA Low-density lipoprotein receptor 1 pr... 46 6e-05
sp|Q99088|LDLR2_XENLA Low-density lipoprotein receptor 2 pr... 45 1e-04
sp|P98074|ENTK_PIG Enteropeptidase precursor (Enterokinase)... 43 5e-04
sp|P98073|ENTK_HUMAN Enteropeptidase precursor (Enterokinas... 42 0.002
sp|P35953|VLDLR_RABIT Very low-density lipoprotein receptor... 40 0.006
sp|P98165|VLDLR_CHICK Very low-density lipoprotein receptor... 39 0.008
sp|Q9JI18|LRP1B_MOUSE Low-density lipoprotein receptor-rela... 39 0.010
sp|P98072|ENTK_BOVIN Enteropeptidase precursor (Enterokinas... 39 0.013
sp|Q95209|SORL_RABIT Sortilin-related receptor precursor (S... 39 0.013
sp|Q9NZR2|LRP1B_HUMAN Low-density lipoprotein receptor-rela... 39 0.013
>sp|Q99087|LDLR1_XENLA Low-density lipoprotein receptor 1 precursor (LDL receptor 1)
Length = 909
Score = 46.2 bits (108), Expect = 6e-05
Identities = 26/66 (39%), Positives = 37/66 (56%)
Frame = +3
Query: 108 VCPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALCIAKNRPPVVLLEQFLVKWKDS 287
VC + + + C+SG C+S DF+CDE+ DC D DE + C A P + F K K
Sbjct: 108 VCADDQ-FTCRSGKCISLDFVCDEDLDCDDGSDE--SYCPAPTCNPAM----FQCKDKGI 160
Query: 288 LIPKVF 305
IPK++
Sbjct: 161 CIPKLW 166
Score = 34.7 bits (78), Expect = 0.19
Identities = 12/30 (40%), Positives = 16/30 (53%)
Frame = +3
Query: 135 CKSGLCLSFDFICDEEFDCPDKYDEDPALC 224
C G C+ + +ICD +C D DE P C
Sbjct: 34 CGDGKCIPYKWICDGSAECKDSSDESPETC 63
Score = 34.3 bits (77), Expect = 0.25
Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Frame = +3
Query: 108 VCPESKP--WPCKSGLCLSFDFICDEEFDCPDKYDEDPALCIAKNRPPVV 251
V P +P + C +G C+ CD E+DC D DE+ + + K P V
Sbjct: 230 VKPTCRPDQFQCNTGTCIHGSRQCDREYDCKDLSDEEGCVNVTKCEGPDV 279
Score = 32.7 bits (73), Expect = 0.73
Identities = 13/25 (52%), Positives = 15/25 (60%)
Frame = +3
Query: 135 CKSGLCLSFDFICDEEFDCPDKYDE 209
C SG C+ + CD FDC DK DE
Sbjct: 202 CGSGECIHMSWKCDGGFDCKDKSDE 226
Score = 32.7 bits (73), Expect = 0.73
Identities = 13/38 (34%), Positives = 21/38 (55%)
Frame = +3
Query: 111 CPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALC 224
C + C+SG C++ D +C+++ DC D DE C
Sbjct: 274 CEGPDVFKCRSGECITMDKVCNKKRDCRDWSDEPLKEC 311
>sp|Q99088|LDLR2_XENLA Low-density lipoprotein receptor 2 precursor (LDL receptor 2)
Length = 892
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/76 (35%), Positives = 40/76 (52%)
Frame = +3
Query: 108 VCPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALCIAKNRPPVVLLEQFLVKWKDS 287
VC + + + C+SG C+S DF+CD++ DC D DE + C A P + F K K
Sbjct: 108 VCADDQ-FTCRSGKCISLDFVCDQDQDCDDGSDE--SYCPAPTCNPAM----FQCKDKGI 160
Query: 288 LIPKVFGNGLPKDLAD 335
IPK++ +D D
Sbjct: 161 CIPKLWACDGDRDCED 176
Score = 34.7 bits (78), Expect = 0.19
Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Frame = +3
Query: 84 HMKRNPGNVCPESKP--WPCKSGLCLSFDFICDEEFDCPDKYDEDPALCIAKNRPPVV 251
H + V P +P + C G C+ CD E+DC D DE+ + + K + P V
Sbjct: 222 HKSDDKDCVKPTCRPDQFQCNDGTCIHGSRQCDREYDCKDLSDEEGCVNVTKCQGPDV 279
Score = 32.0 bits (71), Expect = 1.3
Identities = 13/38 (34%), Positives = 20/38 (52%)
Frame = +3
Query: 111 CPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALC 224
C + C+SG C++ D +C ++ DC D DE C
Sbjct: 274 CQGPDVFKCRSGECITMDKVCHKKRDCRDWTDEPIKEC 311
Score = 31.2 bits (69), Expect = 2.1
Identities = 12/32 (37%), Positives = 16/32 (50%)
Frame = +3
Query: 135 CKSGLCLSFDFICDEEFDCPDKYDEDPALCIA 230
C G C+ + +ICD +C D DE C A
Sbjct: 34 CGDGKCIPYKWICDGSAECKDGSDESSETCRA 65
>sp|P98074|ENTK_PIG Enteropeptidase precursor (Enterokinase) [Contains: Enteropeptidase
non-catalytic mini chain; Enteropeptidase non-catalytic
heavy chain; Enteropeptidase catalytic light chain]
Length = 1034
Score = 43.1 bits (100), Expect = 5e-04
Identities = 21/45 (46%), Positives = 25/45 (55%), Gaps = 3/45 (6%)
Frame = +3
Query: 99 PGNVCPESKPW--PCKSGL-CLSFDFICDEEFDCPDKYDEDPALC 224
PGNV E P PC L C++ D CD E +CPD DED +C
Sbjct: 192 PGNVSIECLPGSRPCADALKCIAVDLFCDGELNCPDGSDEDSKIC 236
>sp|P98073|ENTK_HUMAN Enteropeptidase precursor (Enterokinase) [Contains: Enteropeptidase
non-catalytic heavy chain; Enteropeptidase catalytic
light chain]
Length = 1019
Score = 41.6 bits (96), Expect = 0.002
Identities = 21/45 (46%), Positives = 24/45 (53%), Gaps = 3/45 (6%)
Frame = +3
Query: 99 PGNVCPESKPW--PCKSGL-CLSFDFICDEEFDCPDKYDEDPALC 224
PGNV E P PC L C+ D CD E +CPD DED +C
Sbjct: 177 PGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMC 221
>sp|P35953|VLDLR_RABIT Very low-density lipoprotein receptor precursor (VLDL receptor)
Length = 873
Score = 39.7 bits (91), Expect = 0.006
Identities = 17/40 (42%), Positives = 24/40 (60%)
Frame = +3
Query: 90 KRNPGNVCPESKPWPCKSGLCLSFDFICDEEFDCPDKYDE 209
+ N GNV S + C SG C+S +F+C+ + DC D DE
Sbjct: 146 EENCGNVTCSSDEFTCSSGRCISRNFVCNGQDDCSDGSDE 185
Score = 33.9 bits (76), Expect = 0.33
Identities = 13/39 (33%), Positives = 21/39 (53%)
Frame = +3
Query: 135 CKSGLCLSFDFICDEEFDCPDKYDEDPALCIAKNRPPVV 251
C + C+ ++CD++ DC D+ DE C R PV+
Sbjct: 200 CSTSSCIPISWVCDDDADCSDQSDESLEQC---GRQPVI 235
Score = 32.7 bits (73), Expect = 0.73
Identities = 14/40 (35%), Positives = 20/40 (50%)
Frame = +3
Query: 105 NVCPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALC 224
N C + C+SG C+ +C++E DC D DE C
Sbjct: 316 NQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKEC 355
Score = 32.0 bits (71), Expect = 1.3
Identities = 15/38 (39%), Positives = 20/38 (52%)
Frame = +3
Query: 111 CPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALC 224
C ES + C +G C+ + CD + DC D DE P C
Sbjct: 72 CAESD-FVCNNGQCIPNRWQCDGDPDCEDGSDESPEQC 108
>sp|P98165|VLDLR_CHICK Very low-density lipoprotein receptor precursor (VLDL receptor)
(Vitellogenin receptor) (VTG receptor)
Length = 863
Score = 39.3 bits (90), Expect = 0.008
Identities = 15/38 (39%), Positives = 21/38 (55%)
Frame = +3
Query: 135 CKSGLCLSFDFICDEEFDCPDKYDEDPALCIAKNRPPV 248
CKS C+ ++CD++ DC D DE C + PPV
Sbjct: 218 CKSSTCIPISWVCDDDADCSDHSDESLEQCGRQPAPPV 255
Score = 38.1 bits (87), Expect = 0.017
Identities = 16/40 (40%), Positives = 23/40 (57%)
Frame = +3
Query: 90 KRNPGNVCPESKPWPCKSGLCLSFDFICDEEFDCPDKYDE 209
+ N GNV + + C SG C+S F+C+ + DC D DE
Sbjct: 164 EENCGNVTCSAAEFTCSSGQCISKSFVCNGQDDCSDGSDE 203
Score = 32.0 bits (71), Expect = 1.3
Identities = 16/38 (42%), Positives = 20/38 (52%)
Frame = +3
Query: 111 CPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALC 224
C ES + C SG C+ + CD + DC D DE LC
Sbjct: 90 CAESD-FVCNSGQCVPNRWQCDGDPDCEDGSDESAELC 126
Score = 30.4 bits (67), Expect = 3.6
Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Frame = +3
Query: 96 NPGNVCPESKP--WPCKSGLCLSFDFICDEEFDCPDKYDEDPALC 224
N NV S P + C+SG C+ + +C+ DC D DE C
Sbjct: 329 NCNNVIQCSGPGKFKCRSGECIDINKVCNHHGDCKDWSDEPLKEC 373
Score = 30.0 bits (66), Expect = 4.8
Identities = 15/41 (36%), Positives = 23/41 (56%)
Frame = +3
Query: 111 CPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALCIAK 233
C ES+ + C +G C+ + CD + DC D DE + C+ K
Sbjct: 51 CEESQ-FQCSNGRCIPLLWKCDGDEDCSDGSDE--SACVKK 88
>sp|Q9JI18|LRP1B_MOUSE Low-density lipoprotein receptor-related protein 1B precursor
(Low-density lipoprotein receptor-related protein-deleted
in tumor) (LRP-DIT)
Length = 4599
Score = 38.9 bits (89), Expect = 0.010
Identities = 17/48 (35%), Positives = 27/48 (56%)
Frame = +3
Query: 102 GNVCPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALCIAKNRPP 245
G++C + + + C + LC ++CD E DC D DE P +C+ PP
Sbjct: 3671 GSICRDDE-FLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPP 3717
Score = 38.1 bits (87), Expect = 0.017
Identities = 22/47 (46%), Positives = 25/47 (53%), Gaps = 7/47 (14%)
Frame = +3
Query: 111 CPESKPWP----CKSGLCLSFDFICDEEFDCPDKYDE---DPALCIA 230
CPE K P C +GLC FICD E DC D DE D +C+A
Sbjct: 3352 CPEFKCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLA 3398
Score = 34.7 bits (78), Expect = 0.19
Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 3/41 (7%)
Frame = +3
Query: 111 CPESKPW---PCKSGLCLSFDFICDEEFDCPDKYDEDPALC 224
C S W C C+S +ICD E DC D DE ++C
Sbjct: 2716 CDSSCSWNQFACSVKKCISKHWICDGEDDCGDSLDESDSIC 2756
Score = 34.7 bits (78), Expect = 0.19
Identities = 15/29 (51%), Positives = 18/29 (62%)
Frame = +3
Query: 123 KPWPCKSGLCLSFDFICDEEFDCPDKYDE 209
K + C +G C+S F CD EFDC D DE
Sbjct: 3518 KDFLCSNGDCVSSRFWCDGEFDCADGSDE 3546
Score = 34.3 bits (77), Expect = 0.25
Identities = 14/37 (37%), Positives = 21/37 (56%)
Frame = +3
Query: 99 PGNVCPESKPWPCKSGLCLSFDFICDEEFDCPDKYDE 209
P N C E+ + C + +C+ F+CD + DC D DE
Sbjct: 2801 PNNTCDENA-FMCHNKVCIPKQFVCDHDDDCGDGSDE 2836
Score = 33.5 bits (75), Expect = 0.43
Identities = 14/33 (42%), Positives = 19/33 (57%)
Frame = +3
Query: 111 CPESKPWPCKSGLCLSFDFICDEEFDCPDKYDE 209
C + CKSG C+S + CD + DC D+ DE
Sbjct: 967 CEPLTQFICKSGRCISNKWHCDTDDDCGDRSDE 999
Score = 33.5 bits (75), Expect = 0.43
Identities = 13/36 (36%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Frame = +3
Query: 108 VCPESKPWPCKSG-LCLSFDFICDEEFDCPDKYDED 212
+CP ++P+ C++ +CL + IC+ DC D DE+
Sbjct: 3714 LCPPTRPYRCRNDRICLQLEKICNGINDCGDNSDEE 3749
Score = 32.0 bits (71), Expect = 1.3
Identities = 12/36 (33%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
Frame = +3
Query: 108 VCPESKPWPCKS-GLCLSFDFICDEEFDCPDKYDED 212
+C + C+S G C++ ++CD + DC D+ DE+
Sbjct: 1094 LCDHKTKFSCRSTGRCINNAWVCDGDVDCEDQSDEE 1129
Score = 31.2 bits (69), Expect = 2.1
Identities = 14/28 (50%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Frame = +3
Query: 135 CKSGLCL-SFDFICDEEFDCPDKYDEDP 215
C G CL + + CD +FDCPD DE P
Sbjct: 2852 CADGRCLVNTLWQCDGDFDCPDSSDEAP 2879
Score = 31.2 bits (69), Expect = 2.1
Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 3/37 (8%)
Frame = +3
Query: 135 CKSGLCLSFDFICDEEFDCPDKYDED---PALCIAKN 236
CK+ C+ + CD + DC D DED P C K+
Sbjct: 3483 CKNNNCIPDHWRCDNQNDCSDNSDEDNCKPQTCTLKD 3519
Score = 30.8 bits (68), Expect = 2.8
Identities = 11/31 (35%), Positives = 19/31 (61%)
Frame = +3
Query: 117 ESKPWPCKSGLCLSFDFICDEEFDCPDKYDE 209
++ + C +G C+ ++CD E DC D+ DE
Sbjct: 928 QADQFSCGNGRCIPTAWLCDREDDCGDQTDE 958
Score = 30.8 bits (68), Expect = 2.8
Identities = 23/63 (36%), Positives = 28/63 (44%)
Frame = +3
Query: 108 VCPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALCIAKNRPPVVLLEQFLVKWKDS 287
VC S+ + C SG CLS C+ E DC D DE + K +QF K K
Sbjct: 3593 VCSSSE-YMCASGGCLSASLKCNGEPDCVDGSDEMDCVIECKE-------DQFQCKNKAY 3644
Query: 288 LIP 296
IP
Sbjct: 3645 CIP 3647
Score = 30.4 bits (67), Expect = 3.6
Identities = 13/36 (36%), Positives = 18/36 (50%)
Frame = +3
Query: 135 CKSGLCLSFDFICDEEFDCPDKYDEDPALCIAKNRP 242
CK+ C+ + CD + DC D DED C + P
Sbjct: 852 CKNKHCIQARWKCDGDDDCLDGSDEDSVTCFNHSCP 887
Score = 30.4 bits (67), Expect = 3.6
Identities = 12/25 (48%), Positives = 15/25 (60%)
Frame = +3
Query: 135 CKSGLCLSFDFICDEEFDCPDKYDE 209
CK+G C+ D +CD DC D DE
Sbjct: 2898 CKNGRCIPSDGLCDIRDDCGDGSDE 2922
Score = 30.0 bits (66), Expect = 4.8
Identities = 11/25 (44%), Positives = 16/25 (64%)
Frame = +3
Query: 150 CLSFDFICDEEFDCPDKYDEDPALC 224
C+S ++CD + DCPD+ DE C
Sbjct: 45 CVSQSWLCDGDPDCPDQSDESLDTC 69
Score = 30.0 bits (66), Expect = 4.8
Identities = 12/31 (38%), Positives = 17/31 (54%)
Frame = +3
Query: 117 ESKPWPCKSGLCLSFDFICDEEFDCPDKYDE 209
E + C SG C+ ++CD + DC D DE
Sbjct: 2683 EENYFGCPSGRCILNTWVCDGQKDCEDGLDE 2713
Score = 29.6 bits (65), Expect = 6.2
Identities = 12/41 (29%), Positives = 21/41 (51%)
Frame = +3
Query: 111 CPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALCIAK 233
CP+ + + C++ C+ ++CD DC DE C A+
Sbjct: 886 CPDDQ-FKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTAR 925
Score = 29.6 bits (65), Expect = 6.2
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 5/38 (13%)
Frame = +3
Query: 111 CPESKPWP----CKSGL-CLSFDFICDEEFDCPDKYDE 209
CPE+ P CK+ C+S ++CDE+ DC D DE
Sbjct: 3431 CPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDE 3468
Score = 29.3 bits (64), Expect = 8.1
Identities = 19/69 (27%), Positives = 29/69 (42%), Gaps = 2/69 (2%)
Frame = +3
Query: 135 CKSGLCLSFDFICDEEFDCPDKYDEDPALCIAK--NRPPVVLLEQFLVKWKDSLIPKVFG 308
C SG C+ + CD + DC D DE C + P + +F + + IP ++
Sbjct: 1013 CSSGRCIPGHWACDGDNDCGDFSDETHINCTKEEARSPAGCIGNEFQCRPDGNCIPDLWR 1072
Query: 309 NGLPKDLAD 335
KD D
Sbjct: 1073 CDGEKDCED 1081
Score = 29.3 bits (64), Expect = 8.1
Identities = 14/30 (46%), Positives = 16/30 (53%)
Frame = +3
Query: 135 CKSGLCLSFDFICDEEFDCPDKYDEDPALC 224
C +G CLS + CD DC KY ED C
Sbjct: 3560 CSNGQCLSAKWKCDGHEDC--KYGEDEKNC 3587
>sp|P98072|ENTK_BOVIN Enteropeptidase precursor (Enterokinase) [Contains: Enteropeptidase
non-catalytic heavy chain; Enteropeptidase catalytic
light chain]
Length = 1035
Score = 38.5 bits (88), Expect = 0.013
Identities = 20/45 (44%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Frame = +3
Query: 99 PGNVCPESKPWP--CKSGL-CLSFDFICDEEFDCPDKYDEDPALC 224
PGNV E P C L C++ D CD E +CPD DED C
Sbjct: 192 PGNVSIECPPDSRLCADALKCIAIDLFCDGELNCPDGSDEDNKTC 236
>sp|Q95209|SORL_RABIT Sortilin-related receptor precursor (Sorting protein-related receptor
containing LDLR class A repeats) (SorLA) (SorLA-1)
(Low-density lipoprotein receptor relative with 11
ligand-binding repeats) (LDLR relative with 11
ligand-binding repeats) (LR11)
Length = 2213
Score = 38.5 bits (88), Expect = 0.013
Identities = 16/39 (41%), Positives = 23/39 (58%)
Frame = +3
Query: 117 ESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALCIAK 233
E+ + C++G C+ + CD + DC D DEDPA C K
Sbjct: 1199 EASNFQCRNGHCIPQRWACDGDADCQDGSDEDPANCEKK 1237
Score = 32.3 bits (72), Expect = 0.96
Identities = 12/30 (40%), Positives = 18/30 (60%)
Frame = +3
Query: 120 SKPWPCKSGLCLSFDFICDEEFDCPDKYDE 209
S + C SG+C+ ++CD + DC D DE
Sbjct: 1159 SDEYNCSSGMCIRSSWVCDGDNDCRDWSDE 1188
Score = 32.0 bits (71), Expect = 1.3
Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Frame = +3
Query: 90 KRNPGNVCPESKPWPCK-SGLCLSFDFICDEEFDCPDKYDE 209
K P +C + C+ SG C+ + CD E DC D DE
Sbjct: 1109 KNCPTTICDLDTQFRCQESGTCIPLSYKCDLEDDCGDNSDE 1149
Score = 29.3 bits (64), Expect = 8.1
Identities = 15/46 (32%), Positives = 19/46 (41%), Gaps = 1/46 (2%)
Frame = +3
Query: 108 VCPESKPWPCKSGL-CLSFDFICDEEFDCPDKYDEDPALCIAKNRP 242
+C + CK+ CL +CD C D DEDPA P
Sbjct: 1273 LCTRFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDPAFAGCSRDP 1318
>sp|Q9NZR2|LRP1B_HUMAN Low-density lipoprotein receptor-related protein 1B precursor
(Low-density lipoprotein receptor-related protein-deleted
in tumor) (LRP-DIT)
Length = 4599
Score = 38.5 bits (88), Expect = 0.013
Identities = 16/42 (38%), Positives = 24/42 (57%)
Frame = +3
Query: 102 GNVCPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALCI 227
GN+C + + C + LC ++CD E DC D DE P +C+
Sbjct: 3671 GNIC-RADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCV 3711
Score = 37.0 bits (84), Expect = 0.039
Identities = 15/39 (38%), Positives = 22/39 (56%)
Frame = +3
Query: 99 PGNVCPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDP 215
P N C E+ + C + +C+ F+CD + DC D DE P
Sbjct: 2801 PNNTCDENA-FMCHNKVCIPKQFVCDHDDDCGDGSDESP 2838
Score = 35.8 bits (81), Expect = 0.087
Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 7/47 (14%)
Frame = +3
Query: 111 CPESKPWP----CKSGLCLSFDFICDEEFDCPDKYDE---DPALCIA 230
CPE + P C +GLC FICD E DC D DE D +C++
Sbjct: 3352 CPEFRCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLS 3398
Score = 35.0 bits (79), Expect = 0.15
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 3/41 (7%)
Frame = +3
Query: 111 CPESKPW---PCKSGLCLSFDFICDEEFDCPDKYDEDPALC 224
C S W C + C+S +ICD E DC D DE ++C
Sbjct: 2716 CDSSCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSIC 2756
Score = 33.1 bits (74), Expect = 0.56
Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +3
Query: 96 NPGNVCP---ESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALCIAKNRP 242
NPG P ++ + CK+ C+ + CD + DC D DED C + P
Sbjct: 836 NPGEALPHICKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNHSCP 887
Score = 33.1 bits (74), Expect = 0.56
Identities = 14/33 (42%), Positives = 18/33 (54%)
Frame = +3
Query: 111 CPESKPWPCKSGLCLSFDFICDEEFDCPDKYDE 209
C + CKSG C+S + CD + DC D DE
Sbjct: 967 CEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDE 999
Score = 33.1 bits (74), Expect = 0.56
Identities = 14/29 (48%), Positives = 18/29 (62%)
Frame = +3
Query: 123 KPWPCKSGLCLSFDFICDEEFDCPDKYDE 209
K + C +G C+S F CD +FDC D DE
Sbjct: 3518 KDFLCANGDCVSSRFWCDGDFDCADGSDE 3546
Score = 32.7 bits (73), Expect = 0.73
Identities = 14/33 (42%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
Frame = +3
Query: 120 SKPWPCKSGLCL-SFDFICDEEFDCPDKYDEDP 215
++ + C G CL + + CD +FDCPD DE P
Sbjct: 2847 TEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAP 2879
Score = 32.0 bits (71), Expect = 1.3
Identities = 13/36 (36%), Positives = 21/36 (58%), Gaps = 1/36 (2%)
Frame = +3
Query: 108 VCPESKPWPCKS-GLCLSFDFICDEEFDCPDKYDED 212
+C + C S G C++ ++CD + DC D+ DED
Sbjct: 1094 LCDHKTKFSCWSTGRCINKAWVCDGDIDCEDQSDED 1129
Score = 31.6 bits (70), Expect = 1.6
Identities = 23/76 (30%), Positives = 31/76 (40%)
Frame = +3
Query: 69 YGIETHMKRNPGNVCPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALCIAKNRPPV 248
YG E P + S+ + C S C+S C+ E+DC D DE + K
Sbjct: 3580 YG-EDEKSCEPASPTCSSREYICASDGCISASLKCNGEYDCADGSDEMDCVTECKE---- 3634
Query: 249 VLLEQFLVKWKDSLIP 296
+QF K K IP
Sbjct: 3635 ---DQFRCKNKAHCIP 3647
Score = 30.8 bits (68), Expect = 2.8
Identities = 12/36 (33%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
Frame = +3
Query: 108 VCPESKPWPCKSG-LCLSFDFICDEEFDCPDKYDED 212
+CP ++P C++ +CL + +C+ +C D DED
Sbjct: 3714 LCPSTRPHRCRNNRICLQSEQMCNGIDECGDNSDED 3749
Score = 30.4 bits (67), Expect = 3.6
Identities = 13/31 (41%), Positives = 17/31 (54%)
Frame = +3
Query: 117 ESKPWPCKSGLCLSFDFICDEEFDCPDKYDE 209
E + C SG C+ +ICD + DC D DE
Sbjct: 2683 EENYFSCPSGRCILNTWICDGQKDCEDGRDE 2713
Score = 30.0 bits (66), Expect = 4.8
Identities = 11/25 (44%), Positives = 16/25 (64%)
Frame = +3
Query: 135 CKSGLCLSFDFICDEEFDCPDKYDE 209
C +G C+ ++CD E DC D+ DE
Sbjct: 934 CGNGRCIPRAWLCDREDDCGDQTDE 958
Score = 29.6 bits (65), Expect = 6.2
Identities = 12/41 (29%), Positives = 21/41 (51%)
Frame = +3
Query: 111 CPESKPWPCKSGLCLSFDFICDEEFDCPDKYDEDPALCIAK 233
CP+ + + C++ C+ ++CD DC DE C A+
Sbjct: 886 CPDDQ-FKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTAR 925
Score = 29.6 bits (65), Expect = 6.2
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 5/38 (13%)
Frame = +3
Query: 111 CPESKPWP----CKSGL-CLSFDFICDEEFDCPDKYDE 209
CPE+ P CK+ C+S ++CDE+ DC D DE
Sbjct: 3431 CPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDE 3468
Score = 29.6 bits (65), Expect = 6.2
Identities = 13/37 (35%), Positives = 19/37 (51%), Gaps = 3/37 (8%)
Frame = +3
Query: 135 CKSGLCLSFDFICDEEFDCPDKYDED---PALCIAKN 236
CK+ C+ + CD + DC D DE+ P C K+
Sbjct: 3483 CKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKD 3519
Score = 29.3 bits (64), Expect = 8.1
Identities = 11/25 (44%), Positives = 15/25 (60%)
Frame = +3
Query: 150 CLSFDFICDEEFDCPDKYDEDPALC 224
C+S ++CD + DCPD DE C
Sbjct: 45 CVSQSWLCDGDPDCPDDSDESLDTC 69
Score = 29.3 bits (64), Expect = 8.1
Identities = 11/25 (44%), Positives = 15/25 (60%)
Frame = +3
Query: 135 CKSGLCLSFDFICDEEFDCPDKYDE 209
CK+G C+ +CD + DC D DE
Sbjct: 2898 CKNGRCIPSGGLCDNKDDCGDGSDE 2922
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,962,123
Number of Sequences: 369166
Number of extensions: 1397086
Number of successful extensions: 4124
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3592
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4118
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4699949280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)