Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_F14
(706 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P21522|ROA1_SCHAM Heterogeneous nuclear ribonucleoprotei... 140 3e-33
sp|P07909|ROA1_DROME Heterogeneous nuclear ribonucleoprotei... 131 2e-30
sp|P51990|RO22_XENLA Heterogeneous nuclear ribonucleoprotei... 129 6e-30
sp|P22626|ROA2_HUMAN Heterogeneous nuclear ribonucleoprotei... 128 1e-29
sp|O88569|ROA2_MOUSE Heterogeneous nuclear ribonucleoprotei... 128 1e-29
sp|P51989|RO21_XENLA Heterogeneous nuclear ribonucleoprotei... 128 2e-29
sp|P17130|ROA1_XENLA Heterogeneous nuclear ribonucleoprotei... 127 4e-29
sp|P48810|RB87F_DROME Heterogeneous nuclear ribonucleoprote... 126 5e-29
sp|Q02926|RB97D_DROME Ribonucleoprotein RB97D 125 1e-28
sp|Q28521|ROA1_MACMU Heterogeneous nuclear ribonucleoprotei... 125 1e-28
>sp|P21522|ROA1_SCHAM Heterogeneous nuclear ribonucleoprotein A1, A2/B1 homolog
Length = 342
Score = 140 bits (354), Expect = 3e-33
Identities = 70/118 (59%), Positives = 88/118 (74%), Gaps = 1/118 (0%)
Frame = +2
Query: 35 ERGKKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDD 214
E +KLFIGGL +TT+ESLK + QWGEIVDVVVM+DP+T +SRGFGF+TYS A VDD
Sbjct: 14 EHVRKLFIGGLDYRTTDESLKQHFEQWGEIVDVVVMKDPKTKRSRGFGFITYSRAHMVDD 73
Query: 215 AQGNRPHEVDGIKVDSKRAMPKEDTS-PEFHATVNRLFVGRLKRNVVADDLRQYFGEY 385
AQ RPH+VDG V+ KRA+P+ + PE ATV +LFVG +K + +DLR YF +Y
Sbjct: 74 AQNARPHKVDGRVVEPKRAVPRTEIGRPEAGATVKKLFVGGIKEEMEENDLRDYFKQY 131
Score = 69.7 bits (169), Expect = 7e-12
Identities = 31/81 (38%), Positives = 49/81 (60%)
Frame = +2
Query: 44 KKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDDAQG 223
KKLF+GG+ + E L+ ++ Q+G +V ++ D +T K RGF FV + D VD
Sbjct: 108 KKLFVGGIKEEMEENDLRDYFKQYGTVVSAAIVVDKETRKKRGFAFVEFDDYDPVDKICL 167
Query: 224 NRPHEVDGIKVDSKRAMPKED 286
+R H++ G +D K+A+PK D
Sbjct: 168 SRNHQIRGKHIDVKKALPKGD 188
>sp|P07909|ROA1_DROME Heterogeneous nuclear ribonucleoprotein A1 (hnRNP core protein
A1-A) (PEN repeat clone P9)
Length = 365
Score = 131 bits (330), Expect = 2e-30
Identities = 63/118 (53%), Positives = 87/118 (73%), Gaps = 1/118 (0%)
Frame = +2
Query: 35 ERGKKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDD 214
E +KLFIGGL +TT+E+LK + +WG IVDVVVM+DP+T +SRGFGF+TYS +S +D+
Sbjct: 28 EHMRKLFIGGLDYRTTDENLKAHFEKWGNIVDVVVMKDPRTKRSRGFGFITYSHSSMIDE 87
Query: 215 AQGNRPHEVDGIKVDSKRAMPKED-TSPEFHATVNRLFVGRLKRNVVADDLRQYFGEY 385
AQ +RPH++DG V+ KRA+P++D SP ATV +LFVG LK + +R YF +
Sbjct: 88 AQKSRPHKIDGRVVEPKRAVPRQDIDSPNAGATVKKLFVGALKDDHDEQSIRDYFQHF 145
Score = 72.0 bits (175), Expect = 1e-12
Identities = 32/81 (39%), Positives = 52/81 (64%)
Frame = +2
Query: 44 KKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDDAQG 223
KKLF+G L E+S++ ++ +G IVD+ ++ D +TGK RGF FV + D VD
Sbjct: 122 KKLFVGALKDDHDEQSIRDYFQHFGNIVDINIVIDKETGKKRGFAFVEFDDYDPVDKVVL 181
Query: 224 NRPHEVDGIKVDSKRAMPKED 286
+ H+++G VD K+A+PK++
Sbjct: 182 QKQHQLNGKMVDVKKALPKQN 202
>sp|P51990|RO22_XENLA Heterogeneous nuclear ribonucleoprotein A2 homolog 2 (hnRNP A2(B))
Length = 358
Score = 129 bits (325), Expect = 6e-30
Identities = 63/118 (53%), Positives = 84/118 (71%), Gaps = 1/118 (0%)
Frame = +2
Query: 35 ERGKKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDD 214
E+ +KLFIGGL +TTEESL+ FY QWG++ D VVMRDP + +SRGFGFVT+S + VD
Sbjct: 6 EQFRKLFIGGLSFETTEESLRNFYEQWGQLTDCVVMRDPASKRSRGFGFVTFSCMNEVDA 65
Query: 215 AQGNRPHEVDGIKVDSKRAMPKEDTS-PEFHATVNRLFVGRLKRNVVADDLRQYFGEY 385
A RPH +DG V+ KRA+ +E+++ P H TV +LFVG +K + LR+YF EY
Sbjct: 66 AMSARPHTIDGRVVEPKRAVAREESAKPGAHVTVKKLFVGGIKEDTEEHHLREYFEEY 123
Score = 68.2 bits (165), Expect = 2e-11
Identities = 31/92 (33%), Positives = 54/92 (58%)
Frame = +2
Query: 44 KKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDDAQG 223
KKLF+GG+ T E L+ ++ ++G+I ++ D Q+GK RGFGFVT++D VD
Sbjct: 100 KKLFVGGIKEDTEEHHLREYFEEYGKIESTEIITDKQSGKKRGFGFVTFNDHDPVDKIVL 159
Query: 224 NRPHEVDGIKVDSKRAMPKEDTSPEFHATVNR 319
+ H ++G + ++A+ K++ + NR
Sbjct: 160 QKYHTINGHNAEVRKALSKQEMQDVQNTRNNR 191
>sp|P22626|ROA2_HUMAN Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2 / hnRNP
B1)
Length = 353
Score = 128 bits (322), Expect = 1e-29
Identities = 62/118 (52%), Positives = 82/118 (69%), Gaps = 1/118 (0%)
Frame = +2
Query: 35 ERGKKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDD 214
E+ +KLFIGGL +TTEESL+ +Y QWG++ D VVMRDP + +SRGFGFVT+S + VD
Sbjct: 18 EQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDA 77
Query: 215 AQGNRPHEVDGIKVDSKRAMPKEDT-SPEFHATVNRLFVGRLKRNVVADDLRQYFGEY 385
A RPH +DG V+ KRA+ +E++ P H TV +LFVG +K + LR YF EY
Sbjct: 78 AMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEY 135
Score = 66.6 bits (161), Expect = 6e-11
Identities = 28/81 (34%), Positives = 51/81 (62%)
Frame = +2
Query: 44 KKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDDAQG 223
KKLF+GG+ T E L+ ++ ++G+I + ++ D Q+GK RGFGFVT+ D VD
Sbjct: 112 KKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVL 171
Query: 224 NRPHEVDGIKVDSKRAMPKED 286
+ H ++G + ++A+ +++
Sbjct: 172 QKYHTINGHNAEVRKALSRQE 192
>sp|O88569|ROA2_MOUSE Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2 / hnRNP
B1)
Length = 341
Score = 128 bits (322), Expect = 1e-29
Identities = 62/118 (52%), Positives = 82/118 (69%), Gaps = 1/118 (0%)
Frame = +2
Query: 35 ERGKKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDD 214
E+ +KLFIGGL +TTEESL+ +Y QWG++ D VVMRDP + +SRGFGFVT+S + VD
Sbjct: 6 EQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDA 65
Query: 215 AQGNRPHEVDGIKVDSKRAMPKEDT-SPEFHATVNRLFVGRLKRNVVADDLRQYFGEY 385
A RPH +DG V+ KRA+ +E++ P H TV +LFVG +K + LR YF EY
Sbjct: 66 AMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEY 123
Score = 66.6 bits (161), Expect = 6e-11
Identities = 28/81 (34%), Positives = 51/81 (62%)
Frame = +2
Query: 44 KKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDDAQG 223
KKLF+GG+ T E L+ ++ ++G+I + ++ D Q+GK RGFGFVT+ D VD
Sbjct: 100 KKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVL 159
Query: 224 NRPHEVDGIKVDSKRAMPKED 286
+ H ++G + ++A+ +++
Sbjct: 160 QKYHTINGHNAEVRKALSRQE 180
>sp|P51989|RO21_XENLA Heterogeneous nuclear ribonucleoprotein A2 homolog 1 (hnRNP A2(A))
Length = 346
Score = 128 bits (321), Expect = 2e-29
Identities = 62/118 (52%), Positives = 83/118 (70%), Gaps = 1/118 (0%)
Frame = +2
Query: 35 ERGKKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDD 214
E+ +KLFIGGL +TTEESL+ +Y QWG + D VVMRDP + +SRGFGFVT+S + VD
Sbjct: 6 EQFRKLFIGGLSFETTEESLRNYYEQWGTLTDCVVMRDPASKRSRGFGFVTFSCMNEVDA 65
Query: 215 AQGNRPHEVDGIKVDSKRAMPKEDTS-PEFHATVNRLFVGRLKRNVVADDLRQYFGEY 385
A RPH +DG V+ KRA+ +E+++ P H TV +LFVG +K + LR+YF EY
Sbjct: 66 AMATRPHTIDGRVVEPKRAVAREESAKPGAHVTVKKLFVGGIKEDTEEHHLREYFEEY 123
Score = 66.2 bits (160), Expect = 8e-11
Identities = 30/92 (32%), Positives = 53/92 (57%)
Frame = +2
Query: 44 KKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDDAQG 223
KKLF+GG+ T E L+ ++ ++G+I + ++ D Q+GK RGF FVT+ D VD
Sbjct: 100 KKLFVGGIKEDTEEHHLREYFEEYGKIDSIEIITDKQSGKKRGFAFVTFDDHDPVDKIVL 159
Query: 224 NRPHEVDGIKVDSKRAMPKEDTSPEFHATVNR 319
+ H ++G + ++A+ K++ + NR
Sbjct: 160 QKYHTINGHNAEVRKALSKQEMQDVQNTRNNR 191
>sp|P17130|ROA1_XENLA Heterogeneous nuclear ribonucleoproteins A1 homolog (hnRNP A1)
(Helix-destabilizing protein) (Single-strand binding
protein) (hnRNP core protein A1)
Length = 365
Score = 127 bits (318), Expect = 4e-29
Identities = 63/121 (52%), Positives = 83/121 (68%), Gaps = 1/121 (0%)
Frame = +2
Query: 26 NIDERGKKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASS 205
N E+ +KLFIGGL +TT+ESL+ + QWG + D VVMRDP + +SRGFGFVTY
Sbjct: 8 NEPEQLRKLFIGGLSFETTDESLREHFEQWGTLTDCVVMRDPNSKRSRGFGFVTYLSTDE 67
Query: 206 VDDAQGNRPHEVDGIKVDSKRAMPKEDTS-PEFHATVNRLFVGRLKRNVVADDLRQYFGE 382
VD A RPH+VDG V+ KRA+ +ED+S P H TV ++FVG +K + D LR+YF +
Sbjct: 68 VDAAMTARPHKVDGRVVEPKRAVSREDSSRPGAHLTVKKIFVGGIKEDTEEDHLREYFEQ 127
Query: 383 Y 385
Y
Sbjct: 128 Y 128
Score = 63.2 bits (152), Expect = 7e-10
Identities = 29/81 (35%), Positives = 49/81 (60%)
Frame = +2
Query: 44 KKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDDAQG 223
KK+F+GG+ T E+ L+ ++ Q+G+I + +M D +GK RGF FVT+ D SVD
Sbjct: 105 KKIFVGGIKEDTEEDHLREYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFEDHDSVDKIVI 164
Query: 224 NRPHEVDGIKVDSKRAMPKED 286
+ H V+ ++A+ K++
Sbjct: 165 QKYHTVNNHNSQVRKALSKQE 185
>sp|P48810|RB87F_DROME Heterogeneous nuclear ribonucleoprotein 87F (HRP36.1 protein) (P11
protein)
Length = 385
Score = 126 bits (317), Expect = 5e-29
Identities = 60/118 (50%), Positives = 88/118 (74%), Gaps = 1/118 (0%)
Frame = +2
Query: 35 ERGKKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDD 214
E+ +KLFIGGL +TT++ LK + +WG IVDVVVM+DP+T +SRGFGF+TYS + +D+
Sbjct: 21 EQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITYSQSYMIDN 80
Query: 215 AQGNRPHEVDGIKVDSKRAMPKED-TSPEFHATVNRLFVGRLKRNVVADDLRQYFGEY 385
AQ RPH++DG V+ KRA+P+++ SP ATV +LFVG L+ + + LR+YF ++
Sbjct: 81 AQNARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFVGGLRDDHDEECLREYFKDF 138
Score = 66.2 bits (160), Expect = 8e-11
Identities = 31/81 (38%), Positives = 47/81 (58%)
Frame = +2
Query: 44 KKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDDAQG 223
KKLF+GGL EE L+ ++ +G+IV V ++ D TGK RGF F+ + D VD
Sbjct: 115 KKLFVGGLRDDHDEECLREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDPVDKIIL 174
Query: 224 NRPHEVDGIKVDSKRAMPKED 286
+ H + +D K+A+ K+D
Sbjct: 175 QKTHSIKNKTLDVKKAIAKQD 195
>sp|Q02926|RB97D_DROME Ribonucleoprotein RB97D
Length = 471
Score = 125 bits (314), Expect = 1e-28
Identities = 66/118 (55%), Positives = 86/118 (72%), Gaps = 1/118 (0%)
Frame = +2
Query: 35 ERGKKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDD 214
E +KLFIGGL TTEE+LK FY QWG++VDVVVMRD T +SRGFGF+TY+ + VD
Sbjct: 29 EHLRKLFIGGLAPYTTEENLKLFYGQWGKVVDVVVMRDAATKRSRGFGFITYTKSLMVDR 88
Query: 215 AQGNRPHEVDGIKVDSKRAMPK-EDTSPEFHATVNRLFVGRLKRNVVADDLRQYFGEY 385
AQ NRPH +DG V++KRA+P+ E S E + +V +LFVG LK N + LR+YF ++
Sbjct: 89 AQENRPHIIDGKTVEAKRALPRPERESRETNISVKKLFVGGLKDNHDEECLREYFLQF 146
Score = 64.7 bits (156), Expect = 2e-10
Identities = 31/77 (40%), Positives = 47/77 (61%)
Frame = +2
Query: 44 KKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDDAQG 223
KKLF+GGL EE L+ ++ Q+G +V V ++ D TGK RGF FV + D +VD A
Sbjct: 123 KKLFVGGLKDNHDEECLREYFLQFGNVVSVKLLTDKTTGKRRGFAFVEFDDYDAVDKAIL 182
Query: 224 NRPHEVDGIKVDSKRAM 274
+ H + + VD K+++
Sbjct: 183 KKQHAIKYVHVDVKKSI 199
>sp|Q28521|ROA1_MACMU Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing
protein) (Single-strand binding protein) (hnRNP core
protein A1)
Length = 320
Score = 125 bits (313), Expect = 1e-28
Identities = 61/118 (51%), Positives = 80/118 (67%), Gaps = 1/118 (0%)
Frame = +2
Query: 35 ERGKKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDD 214
E+ +KLFIGGL +TT+ESL+ + QWG + D VVMRDP T +SRGFGFVTY+ VD
Sbjct: 11 EQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEKVDA 70
Query: 215 AQGNRPHEVDGIKVDSKRAMPKEDTS-PEFHATVNRLFVGRLKRNVVADDLRQYFGEY 385
A RPH+VDG V+ KRA+ +ED+ P H TV ++FVG +K + LR YF +Y
Sbjct: 71 AMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQY 128
Score = 66.6 bits (161), Expect = 6e-11
Identities = 30/81 (37%), Positives = 51/81 (62%)
Frame = +2
Query: 44 KKLFIGGLHLKTTEESLKGFYSQWGEIVDVVVMRDPQTGKSRGFGFVTYSDASSVDDAQG 223
KK+F+GG+ T E L+ ++ Q+G+I + +M D +GK RGF FVT+ D +SVD
Sbjct: 105 KKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHNSVDKIVI 164
Query: 224 NRPHEVDGIKVDSKRAMPKED 286
+ H V+G + ++A+ K++
Sbjct: 165 QKYHTVNGHNCEVRKALSKQE 185
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,121,443
Number of Sequences: 369166
Number of extensions: 1520048
Number of successful extensions: 5009
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4533
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4906
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6170718545
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)