Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_003_E02 (644 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P45878|FKBP2_MOUSE FK506-binding protein 2 precursor (Pe... 156 5e-38 sp|P26885|FKBP2_HUMAN FK506-binding protein 2 precursor (Pe... 155 1e-37 sp|Q38935|FK21_ARATH FK506-binding protein 2-1 precursor (P... 138 1e-32 sp|P32472|FKBP2_YEAST FK506-binding protein 2 precursor (Pe... 137 2e-32 sp|Q38936|FK22_ARATH FK506-binding protein 2-2 precursor (P... 133 3e-31 sp|Q41649|FKB15_VICFA FK506-binding protein 2 precursor (Pe... 129 8e-30 sp|Q38931|FKB70_ARATH 70 kDa peptidylprolyl isomerase (Pept... 122 6e-28 sp|P20081|FKBP_YEAST FK506-binding protein 1 (FKBP) (Peptid... 112 6e-25 sp|P0A0W3|FKBP_NEIMC FK506-binding protein (Peptidyl-prolyl... 112 6e-25 sp|P0A0W2|FKBP_NEIMB FK506-binding protein (Peptidyl-prolyl... 110 2e-24
>sp|P45878|FKBP2_MOUSE FK506-binding protein 2 precursor (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (13 kDa FKBP) (FKBP-13) Length = 140 Score = 156 bits (394), Expect = 5e-38 Identities = 75/114 (65%), Positives = 91/114 (79%) Frame = +3 Query: 60 ELRIGIKKRVQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVIKG 239 +L+IG+KKRV C K++ GDV+HMHYTG L +DGT+FDSSL + P F+LG GQVIKG Sbjct: 28 KLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL-EDGTEFDSSLPQNQPFVFSLGTGQVIKG 86 Query: 240 WDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKIDPRSEL 401 WD G+ GMC GEKRKL IPS + YG+ G+PPKIP ATLVFEVEL+KI+ RSEL Sbjct: 87 WDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRSEL 140
>sp|P26885|FKBP2_HUMAN FK506-binding protein 2 precursor (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (13 kDa FKBP) (FKBP-13) Length = 142 Score = 155 bits (391), Expect = 1e-37 Identities = 74/114 (64%), Positives = 91/114 (79%) Frame = +3 Query: 60 ELRIGIKKRVQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVIKG 239 +L+IG+KKRV C K++ GDV+HMHYTG L +DGT+FDSSL + P F+LG GQVIKG Sbjct: 30 KLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL-EDGTEFDSSLPQNQPFVFSLGTGQVIKG 88 Query: 240 WDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKIDPRSEL 401 WD G+ GMC GEKRKL IPS + YG+ G+PPKIP ATLVFEVEL+KI+ R+EL Sbjct: 89 WDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRTEL 142
>sp|Q38935|FK21_ARATH FK506-binding protein 2-1 precursor (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15-1) Length = 153 Score = 138 bits (347), Expect = 1e-32 Identities = 68/117 (58%), Positives = 85/117 (72%), Gaps = 2/117 (1%) Frame = +3 Query: 54 INELRIGIKKRVQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVI 233 + EL+IG+K + Q C +A GD I +HY G L DGT FDSS +RGDP++F LG GQVI Sbjct: 31 VTELQIGVKYKPQKCDLQAHKGDKIKVHYRGKL-TDGTVFDSSFERGDPIEFELGTGQVI 89 Query: 234 KGWDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKI--DPRSE 398 GWD G+ G CVGEKRKL IPS + YGD+GSPPKIP ATL+F+ EL+ + +P SE Sbjct: 90 PGWDQGLLGACVGEKRKLKIPSKLGYGDNGSPPKIPGGATLIFDTELVAVNGEPSSE 146
>sp|P32472|FKBP2_YEAST FK506-binding protein 2 precursor (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (FKBP-13) (FKBP-15) Length = 135 Score = 137 bits (345), Expect = 2e-32 Identities = 66/112 (58%), Positives = 83/112 (74%), Gaps = 2/112 (1%) Frame = +3 Query: 54 INELRIGIKKR--VQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQ 227 +++L IGI KR V+DC KA GD + +HYTG+L + GT FDSS RG P+ F LG+G+ Sbjct: 20 LSDLEIGIIKRIPVEDCLIKAMPGDKVKVHYTGSLLESGTVFDSSYSRGSPIAFELGVGR 79 Query: 228 VIKGWDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKI 383 VIKGWD G+ GMCVGEKRKL IPS +AYG+ G P IPP A LVF+VEL+ + Sbjct: 80 VIKGWDQGVAGMCVGEKRKLQIPSSLAYGERGVPGVIPPSADLVFDVELVDV 131
>sp|Q38936|FK22_ARATH FK506-binding protein 2-2 precursor (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15-2) Length = 163 Score = 133 bits (335), Expect = 3e-31 Identities = 63/113 (55%), Positives = 82/113 (72%) Frame = +3 Query: 54 INELRIGIKKRVQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVI 233 ++EL+IG+K + + C +A GD I +HY G L DGT FDSS +RGDP +F LG GQVI Sbjct: 31 VSELQIGVKFKPKTCEVQAHKGDTIKVHYRGKL-TDGTVFDSSFERGDPFEFKLGSGQVI 89 Query: 234 KGWDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKIDPR 392 KGWD G+ G CVGEKRKL IP+ + YG+ GSPP IP ATL+F+ ELI ++ + Sbjct: 90 KGWDQGLLGACVGEKRKLKIPAKLGYGEQGSPPTIPGGATLIFDTELIAVNEK 142
>sp|Q41649|FKB15_VICFA FK506-binding protein 2 precursor (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15) Length = 151 Score = 129 bits (323), Expect = 8e-30 Identities = 62/130 (47%), Positives = 85/130 (65%) Frame = +3 Query: 6 LFQIVCSEETKSTKKPINELRIGIKKRVQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSL 185 +F I + + + EL+IG+K + C +A GD + +HY G L DGT FDSS Sbjct: 12 IFIIASALVAAKSAADVTELQIGVKYKPASCEVQAHKGDKVKVHYRGKL-TDGTVFDSSF 70 Query: 186 DRGDPLKFTLGMGQVIKGWDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFE 365 +R P+ F LG GQVIKGWD G+ GMC+GEKRKL IP+ + YG+ GSPP IP ATL+F+ Sbjct: 71 ERNSPIDFELGGGQVIKGWDQGLLGMCLGEKRKLKIPAKLGYGEQGSPPTIPGGATLIFD 130 Query: 366 VELIKIDPRS 395 EL+ ++ +S Sbjct: 131 TELVGVNDKS 140
>sp|Q38931|FKB70_ARATH 70 kDa peptidylprolyl isomerase (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (Peptidylprolyl isomerase ROF1) Length = 551 Score = 122 bits (307), Expect = 6e-28 Identities = 63/112 (56%), Positives = 80/112 (71%), Gaps = 3/112 (2%) Frame = +3 Query: 60 ELRIGIKKRVQ---DCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQV 230 E++ G+KK++ + E ++GD + +HYTGTL D GTKFDSS DR P KFTLG GQV Sbjct: 35 EIQQGLKKKLLKEGEGYETPENGDEVEVHYTGTLLD-GTKFDSSRDRATPFKFTLGQGQV 93 Query: 231 IKGWDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKID 386 IKGWD+GI+ M GE IP+ +AYG+SGSPP IP ATL F+VEL+K D Sbjct: 94 IKGWDIGIKTMKKGENAVFTIPAELAYGESGSPPTIPANATLQFDVELLKWD 145
Score = 45.1 bits (105), Expect = 2e-04 Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 8/133 (6%) Frame = +3 Query: 24 SEETKSTKKPINELRIGIKKRVQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRG--- 194 +++ K KK + E D E+ +G V+ + G L DGT F L +G Sbjct: 268 TDDNKVVKKVLKE---------GDGYERPNEGAVVKVKLIGKL-QDGTVF---LKKGHGE 314 Query: 195 --DPLKFTLGMGQVIKGWDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPK---IPPKATLV 359 +P +F QV+ G D + M GE + I A+G + S + +PP +T+ Sbjct: 315 NEEPFEFKTDEEQVVDGLDRAVMKMKKGEVALVTIDPEYAFGSNESQQELAVVPPNSTVT 374 Query: 360 FEVELIKIDPRSE 398 +EV+L+ D E Sbjct: 375 YEVDLLTFDKERE 387
Score = 38.5 bits (88), Expect = 0.015 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 5/105 (4%) Frame = +3 Query: 102 EKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVIKGWDLGIQGMCVGEKR 281 E KD D + + + L +DGT S D ++FT+ G ++ M GEK Sbjct: 168 ENPKDLDEVLVKFEAKL-EDGTVVGKS----DGVEFTVKDGHFCPALTKAVKTMKKGEKV 222 Query: 282 KLFIPSHMAYGDSGSPPK-----IPPKATLVFEVELIKIDPRSEL 401 L + +G+ G P +PP ATL +EL+ SE+ Sbjct: 223 LLTVKPQYGFGEKGKPASAGEGAVPPNATLEINLELVSWKTVSEV 267
>sp|P20081|FKBP_YEAST FK506-binding protein 1 (FKBP) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 114 Score = 112 bits (281), Expect = 6e-25 Identities = 53/92 (57%), Positives = 70/92 (76%) Frame = +3 Query: 111 KDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVIKGWDLGIQGMCVGEKRKLF 290 K GD++ +HYTGTL ++G KFDSS+DRG P + +G+GQVIKGWD+GI + VGEK +L Sbjct: 24 KTGDLVTIHYTGTL-ENGQKFDSSVDRGSPFQCNIGVGQVIKGWDVGIPKLSVGEKARLT 82 Query: 291 IPSHMAYGDSGSPPKIPPKATLVFEVELIKID 386 IP AYG G P IPP +TLVF+VEL+K++ Sbjct: 83 IPGPYAYGPRGFPGLIPPNSTLVFDVELLKVN 114
>sp|P0A0W3|FKBP_NEIMC FK506-binding protein (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 109 Score = 112 bits (281), Expect = 6e-25 Identities = 59/94 (62%), Positives = 68/94 (72%) Frame = +3 Query: 102 EKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVIKGWDLGIQGMCVGEKR 281 ++A G I +HYTG L +DGTKFDSSLDR PL TLG+GQVIKGWD G GM G KR Sbjct: 15 KEAVKGKEITVHYTGWL-EDGTKFDSSLDRRQPLTITLGVGQVIKGWDEGFGGMKEGGKR 73 Query: 282 KLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKI 383 KL IPS M YG G+ IPP ATL+FEVEL+K+ Sbjct: 74 KLTIPSEMGYGAHGAGGVIPPHATLIFEVELLKV 107
>sp|P0A0W2|FKBP_NEIMB FK506-binding protein (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 109 Score = 110 bits (276), Expect = 2e-24 Identities = 58/94 (61%), Positives = 68/94 (72%) Frame = +3 Query: 102 EKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVIKGWDLGIQGMCVGEKR 281 ++A G I +HYTG L ++GTKFDSSLDR PL TLG+GQVIKGWD G GM G KR Sbjct: 15 KEAVKGKEITVHYTGWL-ENGTKFDSSLDRRQPLTITLGVGQVIKGWDEGFGGMKEGGKR 73 Query: 282 KLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKI 383 KL IPS M YG G+ IPP ATL+FEVEL+K+ Sbjct: 74 KLTIPSEMGYGAHGAGGVIPPHATLIFEVELLKV 107
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 68,843,645 Number of Sequences: 369166 Number of extensions: 1454358 Number of successful extensions: 3356 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3161 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3266 length of database: 68,354,980 effective HSP length: 106 effective length of database: 48,773,070 effective search space used: 5267491560 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)