Planarian EST Database


Dr_sW_003_E02

BLASTX 2.2.12 [Aug-07-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Dr_sW_003_E02
         (644 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P45878|FKBP2_MOUSE  FK506-binding protein 2 precursor (Pe...   156   5e-38
sp|P26885|FKBP2_HUMAN  FK506-binding protein 2 precursor (Pe...   155   1e-37
sp|Q38935|FK21_ARATH  FK506-binding protein 2-1 precursor (P...   138   1e-32
sp|P32472|FKBP2_YEAST  FK506-binding protein 2 precursor (Pe...   137   2e-32
sp|Q38936|FK22_ARATH  FK506-binding protein 2-2 precursor (P...   133   3e-31
sp|Q41649|FKB15_VICFA  FK506-binding protein 2 precursor (Pe...   129   8e-30
sp|Q38931|FKB70_ARATH  70 kDa peptidylprolyl isomerase (Pept...   122   6e-28
sp|P20081|FKBP_YEAST  FK506-binding protein 1 (FKBP) (Peptid...   112   6e-25
sp|P0A0W3|FKBP_NEIMC  FK506-binding protein (Peptidyl-prolyl...   112   6e-25
sp|P0A0W2|FKBP_NEIMB  FK506-binding protein (Peptidyl-prolyl...   110   2e-24
>sp|P45878|FKBP2_MOUSE FK506-binding protein 2 precursor (Peptidyl-prolyl cis-trans
           isomerase) (PPIase) (Rotamase) (13 kDa FKBP) (FKBP-13)
          Length = 140

 Score =  156 bits (394), Expect = 5e-38
 Identities = 75/114 (65%), Positives = 91/114 (79%)
 Frame = +3

Query: 60  ELRIGIKKRVQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVIKG 239
           +L+IG+KKRV  C  K++ GDV+HMHYTG L +DGT+FDSSL +  P  F+LG GQVIKG
Sbjct: 28  KLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL-EDGTEFDSSLPQNQPFVFSLGTGQVIKG 86

Query: 240 WDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKIDPRSEL 401
           WD G+ GMC GEKRKL IPS + YG+ G+PPKIP  ATLVFEVEL+KI+ RSEL
Sbjct: 87  WDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRSEL 140
>sp|P26885|FKBP2_HUMAN FK506-binding protein 2 precursor (Peptidyl-prolyl cis-trans
           isomerase) (PPIase) (Rotamase) (13 kDa FKBP) (FKBP-13)
          Length = 142

 Score =  155 bits (391), Expect = 1e-37
 Identities = 74/114 (64%), Positives = 91/114 (79%)
 Frame = +3

Query: 60  ELRIGIKKRVQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVIKG 239
           +L+IG+KKRV  C  K++ GDV+HMHYTG L +DGT+FDSSL +  P  F+LG GQVIKG
Sbjct: 30  KLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL-EDGTEFDSSLPQNQPFVFSLGTGQVIKG 88

Query: 240 WDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKIDPRSEL 401
           WD G+ GMC GEKRKL IPS + YG+ G+PPKIP  ATLVFEVEL+KI+ R+EL
Sbjct: 89  WDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRTEL 142
>sp|Q38935|FK21_ARATH FK506-binding protein 2-1 precursor (Peptidyl-prolyl cis-trans
           isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15-1)
          Length = 153

 Score =  138 bits (347), Expect = 1e-32
 Identities = 68/117 (58%), Positives = 85/117 (72%), Gaps = 2/117 (1%)
 Frame = +3

Query: 54  INELRIGIKKRVQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVI 233
           + EL+IG+K + Q C  +A  GD I +HY G L  DGT FDSS +RGDP++F LG GQVI
Sbjct: 31  VTELQIGVKYKPQKCDLQAHKGDKIKVHYRGKL-TDGTVFDSSFERGDPIEFELGTGQVI 89

Query: 234 KGWDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKI--DPRSE 398
            GWD G+ G CVGEKRKL IPS + YGD+GSPPKIP  ATL+F+ EL+ +  +P SE
Sbjct: 90  PGWDQGLLGACVGEKRKLKIPSKLGYGDNGSPPKIPGGATLIFDTELVAVNGEPSSE 146
>sp|P32472|FKBP2_YEAST FK506-binding protein 2 precursor (Peptidyl-prolyl cis-trans
           isomerase) (PPIase) (Rotamase) (FKBP-13) (FKBP-15)
          Length = 135

 Score =  137 bits (345), Expect = 2e-32
 Identities = 66/112 (58%), Positives = 83/112 (74%), Gaps = 2/112 (1%)
 Frame = +3

Query: 54  INELRIGIKKR--VQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQ 227
           +++L IGI KR  V+DC  KA  GD + +HYTG+L + GT FDSS  RG P+ F LG+G+
Sbjct: 20  LSDLEIGIIKRIPVEDCLIKAMPGDKVKVHYTGSLLESGTVFDSSYSRGSPIAFELGVGR 79

Query: 228 VIKGWDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKI 383
           VIKGWD G+ GMCVGEKRKL IPS +AYG+ G P  IPP A LVF+VEL+ +
Sbjct: 80  VIKGWDQGVAGMCVGEKRKLQIPSSLAYGERGVPGVIPPSADLVFDVELVDV 131
>sp|Q38936|FK22_ARATH FK506-binding protein 2-2 precursor (Peptidyl-prolyl cis-trans
           isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15-2)
          Length = 163

 Score =  133 bits (335), Expect = 3e-31
 Identities = 63/113 (55%), Positives = 82/113 (72%)
 Frame = +3

Query: 54  INELRIGIKKRVQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVI 233
           ++EL+IG+K + + C  +A  GD I +HY G L  DGT FDSS +RGDP +F LG GQVI
Sbjct: 31  VSELQIGVKFKPKTCEVQAHKGDTIKVHYRGKL-TDGTVFDSSFERGDPFEFKLGSGQVI 89

Query: 234 KGWDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKIDPR 392
           KGWD G+ G CVGEKRKL IP+ + YG+ GSPP IP  ATL+F+ ELI ++ +
Sbjct: 90  KGWDQGLLGACVGEKRKLKIPAKLGYGEQGSPPTIPGGATLIFDTELIAVNEK 142
>sp|Q41649|FKB15_VICFA FK506-binding protein 2 precursor (Peptidyl-prolyl cis-trans
           isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15)
          Length = 151

 Score =  129 bits (323), Expect = 8e-30
 Identities = 62/130 (47%), Positives = 85/130 (65%)
 Frame = +3

Query: 6   LFQIVCSEETKSTKKPINELRIGIKKRVQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSL 185
           +F I  +     +   + EL+IG+K +   C  +A  GD + +HY G L  DGT FDSS 
Sbjct: 12  IFIIASALVAAKSAADVTELQIGVKYKPASCEVQAHKGDKVKVHYRGKL-TDGTVFDSSF 70

Query: 186 DRGDPLKFTLGMGQVIKGWDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFE 365
           +R  P+ F LG GQVIKGWD G+ GMC+GEKRKL IP+ + YG+ GSPP IP  ATL+F+
Sbjct: 71  ERNSPIDFELGGGQVIKGWDQGLLGMCLGEKRKLKIPAKLGYGEQGSPPTIPGGATLIFD 130

Query: 366 VELIKIDPRS 395
            EL+ ++ +S
Sbjct: 131 TELVGVNDKS 140
>sp|Q38931|FKB70_ARATH 70 kDa peptidylprolyl isomerase (Peptidyl-prolyl cis-trans
           isomerase) (PPIase) (Rotamase) (Peptidylprolyl isomerase
           ROF1)
          Length = 551

 Score =  122 bits (307), Expect = 6e-28
 Identities = 63/112 (56%), Positives = 80/112 (71%), Gaps = 3/112 (2%)
 Frame = +3

Query: 60  ELRIGIKKRVQ---DCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQV 230
           E++ G+KK++    +  E  ++GD + +HYTGTL D GTKFDSS DR  P KFTLG GQV
Sbjct: 35  EIQQGLKKKLLKEGEGYETPENGDEVEVHYTGTLLD-GTKFDSSRDRATPFKFTLGQGQV 93

Query: 231 IKGWDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKID 386
           IKGWD+GI+ M  GE     IP+ +AYG+SGSPP IP  ATL F+VEL+K D
Sbjct: 94  IKGWDIGIKTMKKGENAVFTIPAELAYGESGSPPTIPANATLQFDVELLKWD 145

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 8/133 (6%)
 Frame = +3

Query: 24  SEETKSTKKPINELRIGIKKRVQDCTEKAKDGDVIHMHYTGTLYDDGTKFDSSLDRG--- 194
           +++ K  KK + E          D  E+  +G V+ +   G L  DGT F   L +G   
Sbjct: 268 TDDNKVVKKVLKE---------GDGYERPNEGAVVKVKLIGKL-QDGTVF---LKKGHGE 314

Query: 195 --DPLKFTLGMGQVIKGWDLGIQGMCVGEKRKLFIPSHMAYGDSGSPPK---IPPKATLV 359
             +P +F     QV+ G D  +  M  GE   + I    A+G + S  +   +PP +T+ 
Sbjct: 315 NEEPFEFKTDEEQVVDGLDRAVMKMKKGEVALVTIDPEYAFGSNESQQELAVVPPNSTVT 374

Query: 360 FEVELIKIDPRSE 398
           +EV+L+  D   E
Sbjct: 375 YEVDLLTFDKERE 387

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 5/105 (4%)
 Frame = +3

Query: 102 EKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVIKGWDLGIQGMCVGEKR 281
           E  KD D + + +   L +DGT    S    D ++FT+  G         ++ M  GEK 
Sbjct: 168 ENPKDLDEVLVKFEAKL-EDGTVVGKS----DGVEFTVKDGHFCPALTKAVKTMKKGEKV 222

Query: 282 KLFIPSHMAYGDSGSPPK-----IPPKATLVFEVELIKIDPRSEL 401
            L +     +G+ G P       +PP ATL   +EL+     SE+
Sbjct: 223 LLTVKPQYGFGEKGKPASAGEGAVPPNATLEINLELVSWKTVSEV 267
>sp|P20081|FKBP_YEAST FK506-binding protein 1 (FKBP) (Peptidyl-prolyl cis-trans
           isomerase) (PPIase) (Rapamycin-binding protein)
          Length = 114

 Score =  112 bits (281), Expect = 6e-25
 Identities = 53/92 (57%), Positives = 70/92 (76%)
 Frame = +3

Query: 111 KDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVIKGWDLGIQGMCVGEKRKLF 290
           K GD++ +HYTGTL ++G KFDSS+DRG P +  +G+GQVIKGWD+GI  + VGEK +L 
Sbjct: 24  KTGDLVTIHYTGTL-ENGQKFDSSVDRGSPFQCNIGVGQVIKGWDVGIPKLSVGEKARLT 82

Query: 291 IPSHMAYGDSGSPPKIPPKATLVFEVELIKID 386
           IP   AYG  G P  IPP +TLVF+VEL+K++
Sbjct: 83  IPGPYAYGPRGFPGLIPPNSTLVFDVELLKVN 114
>sp|P0A0W3|FKBP_NEIMC FK506-binding protein (Peptidyl-prolyl cis-trans isomerase)
           (PPIase) (Rotamase)
          Length = 109

 Score =  112 bits (281), Expect = 6e-25
 Identities = 59/94 (62%), Positives = 68/94 (72%)
 Frame = +3

Query: 102 EKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVIKGWDLGIQGMCVGEKR 281
           ++A  G  I +HYTG L +DGTKFDSSLDR  PL  TLG+GQVIKGWD G  GM  G KR
Sbjct: 15  KEAVKGKEITVHYTGWL-EDGTKFDSSLDRRQPLTITLGVGQVIKGWDEGFGGMKEGGKR 73

Query: 282 KLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKI 383
           KL IPS M YG  G+   IPP ATL+FEVEL+K+
Sbjct: 74  KLTIPSEMGYGAHGAGGVIPPHATLIFEVELLKV 107
>sp|P0A0W2|FKBP_NEIMB FK506-binding protein (Peptidyl-prolyl cis-trans isomerase)
           (PPIase) (Rotamase)
          Length = 109

 Score =  110 bits (276), Expect = 2e-24
 Identities = 58/94 (61%), Positives = 68/94 (72%)
 Frame = +3

Query: 102 EKAKDGDVIHMHYTGTLYDDGTKFDSSLDRGDPLKFTLGMGQVIKGWDLGIQGMCVGEKR 281
           ++A  G  I +HYTG L ++GTKFDSSLDR  PL  TLG+GQVIKGWD G  GM  G KR
Sbjct: 15  KEAVKGKEITVHYTGWL-ENGTKFDSSLDRRQPLTITLGVGQVIKGWDEGFGGMKEGGKR 73

Query: 282 KLFIPSHMAYGDSGSPPKIPPKATLVFEVELIKI 383
           KL IPS M YG  G+   IPP ATL+FEVEL+K+
Sbjct: 74  KLTIPSEMGYGAHGAGGVIPPHATLIFEVELLKV 107
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,843,645
Number of Sequences: 369166
Number of extensions: 1454358
Number of successful extensions: 3356
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3161
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3266
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5267491560
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)