Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_D09
(628 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P20585|MSH3_HUMAN DNA mismatch repair protein Msh3 (Dive... 34 0.27
sp|P20641|VN02_VACCC Protein N2 32 1.7
sp|P14357|VN02_VACCV Protein N2 31 3.0
sp|Q9UBT6|POLK_HUMAN DNA polymerase kappa (DINB protein) (D... 30 3.9
sp|Q5HU00|ISPE_CAMJR 4-diphosphocytidyl-2-C-methyl-D-erythr... 30 5.0
sp|O76014|K1H7_HUMAN Keratin, type I cuticular Ha7 (Hair ke... 30 5.0
sp|Q9US08|SPO3_SCHPO Sporulation-specific protein 3 30 5.0
sp|P38677|CMLE_NEUCR Carboxy-cis,cis-muconate cyclase (3-ca... 30 6.6
sp|P34019|VN02_VARV Protein N2 30 6.6
sp|P38346|YB9O_YEAST Hypothetical 61.3 kDa protein in MRPL3... 30 6.6
>sp|P20585|MSH3_HUMAN DNA mismatch repair protein Msh3 (Divergent upstream protein) (DUP)
(Mismatch repair protein 1) (MRP1)
Length = 1137
Score = 34.3 bits (77), Expect = 0.27
Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 3/100 (3%)
Frame = +3
Query: 267 QKFLMCVSL--KLKTELHYLIHD-NASIHNDVLTTTECHKILKLPPYSPFLNPIENYFGT 437
Q+F + V LK+E +I N+ I +D+L T IL++P L+P+E+Y
Sbjct: 636 QEFFLIVKTLYHLKSEFQAIIPAVNSHIQSDLLRTV----ILEIPE---LLSPVEHYLKI 688
Query: 438 IKSKLRKKLTNFDFGSNQSKFGTIKNTVDEIMAVEKEINL 557
+ + K + + S F IK DEI V EI +
Sbjct: 689 LNEQAAKVGDKTELFKDLSDFPLIKKRKDEIQGVIDEIRM 728
>sp|P20641|VN02_VACCC Protein N2
Length = 175
Score = 31.6 bits (70), Expect = 1.7
Identities = 28/132 (21%), Positives = 52/132 (39%), Gaps = 7/132 (5%)
Frame = +3
Query: 246 SVTQSIYQKFLMCVSLKLKTELHYLIHDNASIHNDVLTTTECHKILKLPPYSPF-LNPIE 422
++ I + MC+ + + +++ +++ D L T+CH I + Y ++
Sbjct: 32 NIMDCINRHINMCIQRTYSSSIIAILNRFLTMNKDELNNTQCHIIKEFMTYEQMAIDHYG 91
Query: 423 NYFGTIKSKLRKKLTNFDFGSNQSKFGTIKNT------VDEIMAVEKEINLSKYFHHIKK 584
Y I ++RK+ F IK T VD + V+K I + K
Sbjct: 92 EYVNAILYQIRKRPNQH---HTIDLFKKIKRTPYDTFKVDPVEFVKKVIGFVSILNKYKP 148
Query: 585 FYPDCLYMNNIF 620
Y LY N ++
Sbjct: 149 VYSYVLYENVLY 160
>sp|P14357|VN02_VACCV Protein N2
Length = 175
Score = 30.8 bits (68), Expect = 3.0
Identities = 28/131 (21%), Positives = 51/131 (38%), Gaps = 6/131 (4%)
Frame = +3
Query: 246 SVTQSIYQKFLMCVSLKLKTELHYLIHDNASIHNDVLTTTECHKILKLPPYSPFLNPIEN 425
++ I + MC+ + + ++ ++ D L T+CH I + Y I++
Sbjct: 32 NIMDCINRHINMCIQRTYSSSIIAILDRFLMMNKDELNNTQCHIIKEFMTYEQM--AIDH 89
Query: 426 YFGTIKSKLRKKLTNFDFGSNQSKFGTIKNT------VDEIMAVEKEINLSKYFHHIKKF 587
Y G + + L + + F IK T VD + V+K I + K
Sbjct: 90 YGGYVNAILYQIRKRPNQHHTIDLFKRIKRTRYDTFKVDPVEFVKKVIGFVSILNKYKPV 149
Query: 588 YPDCLYMNNIF 620
Y LY N ++
Sbjct: 150 YSYVLYENVLY 160
>sp|Q9UBT6|POLK_HUMAN DNA polymerase kappa (DINB protein) (DINP)
Length = 870
Score = 30.4 bits (67), Expect = 3.9
Identities = 31/155 (20%), Positives = 57/155 (36%), Gaps = 31/155 (20%)
Frame = +3
Query: 180 PNISIIMAIRKNGPIHYKVLQGSVTQS------------IYQKFLMCVSLKLKTELHYLI 323
PN +M K+ PI G VT+ +YQ+ + L +T HY +
Sbjct: 337 PNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFL 396
Query: 324 HDNASIHNDVLTTTECHKILKLPPYSPFLNPIENYFGTIKS------------------- 446
H + + + LT K + + +N E + +
Sbjct: 397 HISLGLGSTHLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTV 456
Query: 447 KLRKKLTNFDFGSNQSKFGTIKNTVDEIMAVEKEI 551
++ K NF+ + S ++ +T +EI A+ KE+
Sbjct: 457 TIKLKNVNFEVKTRASTVSSVVSTAEEIFAIAKEL 491
>sp|Q5HU00|ISPE_CAMJR 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK)
(4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase)
sp|Q9PNJ0|ISPE_CAMJE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK)
(4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol
kinase)
Length = 255
Score = 30.0 bits (66), Expect = 5.0
Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Frame = +3
Query: 441 KSKLRKKLTNFD---FGSNQSKFGTIKNTVDEIMAVEKEINLSKYFHHIKKF 587
K+ + KLT FD + +S+F +K+ DE+ V+KE + K F I F
Sbjct: 6 KANIFLKLTGFDSRKYHLLESRFILLKDVFDELELVDKESDSKKEFEIISNF 57
>sp|O76014|K1H7_HUMAN Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7)
Length = 449
Score = 30.0 bits (66), Expect = 5.0
Identities = 25/93 (26%), Positives = 38/93 (40%)
Frame = +3
Query: 144 LPGYLQVPSQRGPNISIIMAIRKNGPIHYKVLQGSVTQSIYQKFLMCVSLKLKTELHYLI 323
LPG +P NI I A KN L G +++ KFL ++ L
Sbjct: 79 LPGTCHIPG----NIGICGAYGKN------TLNGHEKETM--KFLNDRLANYLEKVRQLE 126
Query: 324 HDNASIHNDVLTTTECHKILKLPPYSPFLNPIE 422
+NA + +L ++CH+ P Y + IE
Sbjct: 127 QENAELETTLLERSKCHESTVCPDYQSYFRTIE 159
>sp|Q9US08|SPO3_SCHPO Sporulation-specific protein 3
Length = 1028
Score = 30.0 bits (66), Expect = 5.0
Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 12/155 (7%)
Frame = +3
Query: 183 NISIIMAIRKNGPIHYKVLQGSVTQSIYQKFLMCVSLKLKTELHYLIHDNASIHNDVLTT 362
NI I ++++G I Y+V + + IY L + + LH+ + + + L
Sbjct: 699 NIFISKPLKRSGSI-YEVFSDGIGRVIYGSVLDYEATRNNILLHFGFEIHCAPSEEELIE 757
Query: 363 TE-----CHKILKLPPYSPFLNPIENYFGTI------KSKLRKKLTNFDFGSNQSKFGTI 509
E H +L YS N I + GT K+++ K++ + N+ +I
Sbjct: 758 REEAFKDFHNMLSFK-YSA--NEIYEFCGTHSRAEVHKNEVLKRMAYYLIDENKEI--SI 812
Query: 510 KNTVDEIMAVEKEINLSKYFHHI-KKFYPDCLYMN 611
+ + VE + ++Y + + + FYPD LY+N
Sbjct: 813 LRRILSLRIVEPTTSFTRYEYDLWRTFYPDVLYLN 847
>sp|P38677|CMLE_NEUCR Carboxy-cis,cis-muconate cyclase (3-carboxy-cis,cis-muconate
lactonizing enzyme) (CMLE)
Length = 366
Score = 29.6 bits (65), Expect = 6.6
Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 9/88 (10%)
Frame = +3
Query: 345 NDVLTTTECHKIL--KLPPYSPFLNPIENY--FGTIKS-----KLRKKLTNFDFGSNQSK 497
ND T T +L K PPY+ + NP + +G + S KL K + N+++ N
Sbjct: 89 NDADTNTRAIFLLAAKQPPYAVYANPFYKFAGYGNVFSVSETGKLEKNVQNYEYQENTGI 148
Query: 498 FGTIKNTVDEIMAVEKEINLSKYFHHIK 581
G + + E ++ +K + H K
Sbjct: 149 HGMVFDPT-ETYLYSADLTANKLWTHRK 175
>sp|P34019|VN02_VARV Protein N2
Length = 177
Score = 29.6 bits (65), Expect = 6.6
Identities = 28/131 (21%), Positives = 51/131 (38%), Gaps = 6/131 (4%)
Frame = +3
Query: 246 SVTQSIYQKFLMCVSLKLKTELHYLIHDNASIHNDVLTTTECHKILKLPPYSPFLNPIEN 425
++ I + MC+ + + ++ ++ D L T+CH I + Y I++
Sbjct: 32 NIINCINRHINMCLQHTYSSSIIAILDRFLMMNKDELNNTQCHIIKEFMTYEQM--AIDH 89
Query: 426 YFGTIKSKLRKKLTNFDFGSNQSKFGTIKNT------VDEIMAVEKEINLSKYFHHIKKF 587
Y G + + L + + F IK T VD + V+K I + K
Sbjct: 90 YGGYVNAILYQIRKRPNQHHTIDLFKKIKRTRYDTFKVDPVEFVKKVIGFVSILNKYKPV 149
Query: 588 YPDCLYMNNIF 620
Y LY N ++
Sbjct: 150 YSYVLYENVLY 160
>sp|P38346|YB9O_YEAST Hypothetical 61.3 kDa protein in MRPL37-RIF1 intergenic region
Length = 545
Score = 29.6 bits (65), Expect = 6.6
Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 3/83 (3%)
Frame = +3
Query: 144 LPGYLQVPSQRGPNISIIMAIRKNGPIHYKVLQGSVTQSIYQKFLMCVSLKLKTELHYLI 323
L GYL PS+ P+I +++ K + S+ Y+ FL K+ Y+
Sbjct: 448 LDGYLSEPSRYAPSIDVLL---------LKCFRDSIILPYYESFLHTNDGASKSFQRYIF 498
Query: 324 HD---NASIHNDVLTTTECHKIL 383
+ N D LT +C IL
Sbjct: 499 SEEEQNGVTEEDKLTLLQCFGIL 521
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,901,137
Number of Sequences: 369166
Number of extensions: 1404461
Number of successful extensions: 3811
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3700
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3811
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 4974853140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)