Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_C02
(848 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5KIP8|CWC25_CRYNE Pre-mRNA splicing factor CWC25 42 0.003
sp|Q9UKJ3|K0553_HUMAN Protein KIAA0553 42 0.003
sp|Q9W420|SPT6H_DROME Transcription elongation factor SPT6 38 0.031
sp|P09079|HXB5_MOUSE Homeobox protein Hox-B5 (Hox-2.1) (MU-... 38 0.041
sp|Q9DE13|BAZ2B_CHICK Bromodomain adjacent to zinc finger d... 34 0.45
sp|P09067|HXB5_HUMAN Homeobox protein Hox-B5 (Hox-2A) (HHO.... 34 0.58
sp|P28054|RRPP_PI1HC Phosphoprotein (P protein) 34 0.58
sp|Q8VC48|PEX12_MOUSE Peroxisome assembly protein 12 (Perox... 33 0.76
sp|P37370|VRP1_YEAST Verprolin 33 0.76
sp|P54675|PI3K3_DICDI Phosphatidylinositol 3-kinase 3 (PI3-... 33 1.00
>sp|Q5KIP8|CWC25_CRYNE Pre-mRNA splicing factor CWC25
Length = 434
Score = 41.6 bits (96), Expect = 0.003
Identities = 41/170 (24%), Positives = 65/170 (38%)
Frame = +3
Query: 51 EVRQRLNNQSNSNKELTAVGSKMRRGDHLPGGGNSTSHRRGLSTTTYFGGESLEVTNGTS 230
+ R+R + S E G R G H P G + HR G
Sbjct: 267 DYRRRNDTTRGSFDESPRKGGGNRWGSHGPDGYRRSDHRDDGFRERQRGD---------- 316
Query: 231 YRYRPPPPNRLSRNQNTPQNIRRPRPQSDAAQMSSNTSSVSGQLSPQHYQYAEDSEEDVM 410
R PPP LS N +TP P S AA ++ NTS++ Q + + + ++E
Sbjct: 317 ---RIPPPRHLSYNHSTPDVRPSSPPSSSAAPVNRNTSTLEDQRAARLAAMSASADELYS 373
Query: 411 IPGELMSPTNGQRRSIVESDHRNYASYNQQQQQRIGKSVNNDTRKYQYGL 560
+ ++ + R E D + Y ++Q S N +++ Q GL
Sbjct: 374 SRSKSLAARAEEERREQEKDEKMRQKYGKEQ-----ASANFFSQQSQLGL 418
>sp|Q9UKJ3|K0553_HUMAN Protein KIAA0553
Length = 1089
Score = 41.6 bits (96), Expect = 0.003
Identities = 66/278 (23%), Positives = 95/278 (34%), Gaps = 28/278 (10%)
Frame = +3
Query: 3 TRQDNIRPRSGEYNITEVRQRLNNQSNSNKELTAVGSKMRRGDHLPGGGNST-------- 158
T + + + SGE + ++R + NK S+ PG G+
Sbjct: 282 TEEKSSKAESGEKS----KKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRA 337
Query: 159 ---SHRRGLSTTTYFGGESLEVTNGTSYRYRPP-------PPNRLSRNQNTPQNIR---R 299
S RR L G+ E G+S + PP+ R T ++ R R
Sbjct: 338 QDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHR 397
Query: 300 PRPQSDAAQMSSNTSSVSGQLSPQHYQYAEDSEEDVMIPGELMSPTNGQRRSIVESDHRN 479
+P S +S Q SP Y E+ EED +G+R S S R+
Sbjct: 398 SQPSSGDEDSDDASSHRLHQKSPSQYS-EEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRS 456
Query: 480 YASYNQQQQQRIGKSVNNDTRKYQYGLSYPDHLYCKHHRYYNWHSSVSGDSISPDMTNCK 659
Y+S ++D Y SY D Y + HS S DS D + K
Sbjct: 457 YSS---------SSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSK 507
Query: 660 TEPN----LKSDKEGEI---LSHSTLRSPSLERQLSPG 752
SD + + S S RS + ER S G
Sbjct: 508 HRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRG 545
>sp|Q9W420|SPT6H_DROME Transcription elongation factor SPT6
Length = 1831
Score = 38.1 bits (87), Expect = 0.031
Identities = 40/161 (24%), Positives = 61/161 (37%), Gaps = 26/161 (16%)
Frame = +3
Query: 126 GDHLPGGGNSTSHRRGLSTTTYFGGESLEVTNGTSYRYRPPPPNRLSRNQNTPQNIRRPR 305
G PG G S+SH G S+T FG + T + P S+ N+ P
Sbjct: 1605 GSSAPGAGVSSSH-YGSSSTPSFGAINTPYTPSGQTPFMTPYTPHASQTPRYGHNVPSPS 1663
Query: 306 PQSDAAQ-----MSSNTSS--------------VSG-------QLSPQHYQYAEDSEEDV 407
QS ++Q SS T S V G + P H Q A+++ D
Sbjct: 1664 SQSSSSQRHHYGSSSGTGSTPRYHDMGGGGGGGVGGGGGSNAYSMQPHHQQRAKEN-LDW 1722
Query: 408 MIPGELMSPTNGQRRSIVESDHRNYASYNQQQQQRIGKSVN 530
+ + + Q+ +S H ++ QQQ +G S+N
Sbjct: 1723 QLANDAWARRRPQQHQSHQSYHAQQQHHHSQQQPHMGMSMN 1763
>sp|P09079|HXB5_MOUSE Homeobox protein Hox-B5 (Hox-2.1) (MU-1) (H24.1)
Length = 269
Score = 37.7 bits (86), Expect = 0.041
Identities = 30/109 (27%), Positives = 43/109 (39%)
Frame = +3
Query: 39 YNITEVRQRLNNQSNSNKELTAVGSKMRRGDHLPGGGNSTSHRRGLSTTTYFGGESLEVT 218
YN + +N S S+ AVG R P R+ S+ + ESL T
Sbjct: 47 YNYNGMDLSVNRSSASSSHFGAVGESSRA---FPASAKEPRFRQATSSCSLSSPESLPCT 103
Query: 219 NGTSYRYRPPPPNRLSRNQNTPQNIRRPRPQSDAAQMSSNTSSVSGQLS 365
NG S+ +P + +Q TP + + D A SS + QLS
Sbjct: 104 NGDSHGAKPSASS--PSDQATPASSSANFTEIDEASASSEPEEAASQLS 150
>sp|Q9DE13|BAZ2B_CHICK Bromodomain adjacent to zinc finger domain 2B (Extracellular matrix
protein F22)
Length = 2130
Score = 34.3 bits (77), Expect = 0.45
Identities = 42/206 (20%), Positives = 74/206 (35%), Gaps = 6/206 (2%)
Frame = +3
Query: 147 GNSTSHRRGLSTTTYF------GGESLEVTNGTSYRYRPPPPNRLSRNQNTPQNIRRPRP 308
GNST+ +ST+ G+ VT+G R N++ I+ +P
Sbjct: 118 GNSTTAASAISTSVLSTSIATSAGQVKVVTSGAGGRKYNQEQNKVQLLDTRADKIKDKKP 177
Query: 309 QSDAAQMSSNTSSVSGQLSPQHYQYAEDSEEDVMIPGELMSPTNGQRRSIVESDHRNYAS 488
+ A + SSN+ S SG S + S+ D + E + +S ES+ S
Sbjct: 178 RKKAVESSSNSDSDSGSSSDTSSEGISSSDSDDLEEDE----EEEEDQSAEESEDDESDS 233
Query: 489 YNQQQQQRIGKSVNNDTRKYQYGLSYPDHLYCKHHRYYNWHSSVSGDSISPDMTNCKTEP 668
N+ + K + + K H + R + VS + + +P
Sbjct: 234 ENEAHHENKNKVLMHSGVKDMKTDGQKAHEKSQEKRTHQQIPLVSDSQTHSSFQSQQKQP 293
Query: 669 NLKSDKEGEILSHSTLRSPSLERQLS 746
+ S + I S + S+ + S
Sbjct: 294 QVLSQQLPFIFQSSQAKEESVNKHTS 319
>sp|P09067|HXB5_HUMAN Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1)
Length = 269
Score = 33.9 bits (76), Expect = 0.58
Identities = 29/109 (26%), Positives = 42/109 (38%)
Frame = +3
Query: 39 YNITEVRQRLNNQSNSNKELTAVGSKMRRGDHLPGGGNSTSHRRGLSTTTYFGGESLEVT 218
YN + +N S S+ AVG R P R+ S+ + ESL T
Sbjct: 47 YNYNGMDLSVNRSSASSSHFGAVGESSRA---FPAPAQEPRFRQAASSCSLSSPESLPCT 103
Query: 219 NGTSYRYRPPPPNRLSRNQNTPQNIRRPRPQSDAAQMSSNTSSVSGQLS 365
NG S+ +P + +Q T + + D A SS + QLS
Sbjct: 104 NGDSHGAKPSASS--PSDQATSASSSANFTEIDEASASSEPEEAASQLS 150
>sp|P28054|RRPP_PI1HC Phosphoprotein (P protein)
Length = 568
Score = 33.9 bits (76), Expect = 0.58
Identities = 44/188 (23%), Positives = 73/188 (38%), Gaps = 8/188 (4%)
Frame = +3
Query: 3 TRQDNIRPRSGEYN---ITEVRQRLNNQSNSNKELTAVG--SKMRRGDHLPGGGNSTSHR 167
TR D P + +T+ +++ SN +E G ++RR L G S ++
Sbjct: 134 TRIDEDSPNERRHQRSVLTDEDRKMAEDSNKREEDQVEGFPEEIRRSTPLSDDGESRTNN 193
Query: 168 RGLSTTTYFGGESLEVTNGTSYRYRPPPPNR---LSRNQNTPQNIRRPRPQSDAAQMSSN 338
G S T S T T P P L RN+ P IRR + +S+ Q S
Sbjct: 194 NGRSMET----SSTHSTRITDVIINPSPELEDAVLQRNKRRPTIIRRNQTRSERTQNSEL 249
Query: 339 TSSVSGQLSPQHYQYAEDSEEDVMIPGELMSPTNGQRRSIVESDHRNYASYNQQQQQRIG 518
S S ++ ED G + P N + + +++H N ++ +
Sbjct: 250 HKSTS-----ENSSNLEDHNTKTSPKG--LPPKNEESAATPKNNH------NHRKTKYTM 296
Query: 519 KSVNNDTR 542
+ NN+T+
Sbjct: 297 NNANNNTK 304
>sp|Q8VC48|PEX12_MOUSE Peroxisome assembly protein 12 (Peroxin-12)
Length = 359
Score = 33.5 bits (75), Expect = 0.76
Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 8/85 (9%)
Frame = +3
Query: 54 VRQRLNNQSNSNKELTAVGSKMRRGDHLPGGGNSTSHRRGLSTTTYF--------GGESL 209
++QRL S + + +VG K++ GG + S GLS +F E+
Sbjct: 211 IKQRLVEASAMQEPVRSVGEKIKSALKKAVGGVALSLSTGLSVGVFFLQFLDWWYSSENQ 270
Query: 210 EVTNGTSYRYRPPPPNRLSRNQNTP 284
E + PPPP L N ++P
Sbjct: 271 EAIKSLTALPTPPPPVHLDYNSDSP 295
>sp|P37370|VRP1_YEAST Verprolin
Length = 817
Score = 33.5 bits (75), Expect = 0.76
Identities = 36/192 (18%), Positives = 77/192 (40%), Gaps = 17/192 (8%)
Frame = +3
Query: 225 TSYRYRPPPPNRLSRNQNTPQNIRRPRPQSDAAQMSSNTSSVSGQLSPQHYQYAEDSEED 404
TS PPPP L+ N+ + + QS + SS+++ G P + + ++
Sbjct: 435 TSVPSAPPPPPTLTTNKPSASS-----KQSKISSSSSSSAVTPGGPLPFLAEIQKKRDDR 489
Query: 405 VMIPGELMSPTNGQRRSIVESDHRNYASYNQQQQQRIGKSVNNDTRKYQYGLSYPDHLYC 584
++ G+ T ++ ++ S + + + I S+N + Q G+S+ D +
Sbjct: 490 FVVGGDTGYTTQDKQEDVIGS-----SKDDNVRPSPISPSINPPKQSSQNGMSFLDEIES 544
Query: 585 KHHRYYNWHS----SVSGDSISPDMTNCKTEPNLKS-------------DKEGEILSHST 713
K H+ + ++ D+++P + P + S DK +L
Sbjct: 545 KLHKQTSSNAFNAPPPHTDAMAPPLPPSAPPPPITSLPTPTASGDDHTNDKSETVLGMKK 604
Query: 714 LRSPSLERQLSP 749
++P+L + P
Sbjct: 605 AKAPALPGHVPP 616
>sp|P54675|PI3K3_DICDI Phosphatidylinositol 3-kinase 3 (PI3-kinase) (PtdIns-3-kinase)
(PI3K)
Length = 1585
Score = 33.1 bits (74), Expect = 1.00
Identities = 37/167 (22%), Positives = 65/167 (38%), Gaps = 11/167 (6%)
Frame = +3
Query: 69 NNQSNSNKELTAVGSKMRRGDHLPG-----GGNSTSHRRGLSTTTYFGGESLEVTNGTSY 233
NN SNSN + HL G N+T+ + TT G S+ +TN S
Sbjct: 216 NNNSNSNNNNNGISPSSSPPSHLNGNNNNNNSNNTNSNNTTNATTNSVGFSITMTNSNSL 275
Query: 234 RYRPPPPNRLSRNQNTPQNIRRPRPQSDAAQMSSNTS------SVSGQLSPQHYQYAEDS 395
+S+ N ++ +P S + +S+ ++SG S + + +DS
Sbjct: 276 --------SVSKRMNKFKSWTSSKPTSSSIGFASSPQNNGKPLNISG--SSRFFTSRQDS 325
Query: 396 EEDVMIPGELMSPTNGQRRSIVESDHRNYASYNQQQQQRIGKSVNND 536
+ D++ PT Q E+++ N + N + NN+
Sbjct: 326 KIDLLKSPSSSPPT--QSDIFNENNNNNNNNNNNNNNNNNNNNNNNN 370
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,014,099
Number of Sequences: 369166
Number of extensions: 2177488
Number of successful extensions: 6925
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6409
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6887
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8341863645
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)