Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_A24
(250 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P31713|ISH1_STOHE Kunitz-type proteinase inhibitor SHPI-1 81 7e-16
sp|P81129|ISH2_STOHE Kunitz-type proteinase inhibitor SHPI-2 77 1e-14
sp|P10280|IP52_ANESU Kunitz-type protease inhibitor 5 II (S... 76 3e-14
sp|Q9TWF8|KC3_ANESU Kunitz-type kalicludine 3 (AsKC3) 75 4e-14
sp|O54819|TFPI1_MOUSE Tissue factor pathway inhibitor precu... 74 8e-14
sp|Q9TWF9|KC2_ANESU Kunitz-type kalicludine 2 (AsKC2) 74 8e-14
sp|P82968|MCPI_MELCP Protease inhibitor (McaPI) 74 8e-14
sp|P00993|IBP_CARCR Chelonianin (Basic protease inhibitor) ... 74 8e-14
sp|P10646|TFPI1_HUMAN Tissue factor pathway inhibitor precu... 74 1e-13
sp|P81547|AXP1_ANTAF Kunitz-type proteinase inhibitor AXPI-I 74 1e-13
>sp|P31713|ISH1_STOHE Kunitz-type proteinase inhibitor SHPI-1
Length = 55
Score = 81.3 bits (199), Expect = 7e-16
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +3
Query: 48 CSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIECRARC 200
CS PK+VG C+GYFPR+++++ETGKC FIYGGC GN NNF T +CRA C
Sbjct: 3 CSEPKKVGRCKGYFPRFYFDSETGKCTPFIYGGCGGNGNNFETLHQCRAIC 53
>sp|P81129|ISH2_STOHE Kunitz-type proteinase inhibitor SHPI-2
Length = 55
Score = 77.0 bits (188), Expect = 1e-14
Identities = 31/51 (60%), Positives = 39/51 (76%)
Frame = +3
Query: 48 CSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIECRARC 200
C PK VG C+GYFPR++++++TGKC FIYGGC GN NNF T +CRA C
Sbjct: 3 CLEPKRVGRCKGYFPRFYFDSKTGKCTPFIYGGCGGNGNNFETLHQCRAIC 53
>sp|P10280|IP52_ANESU Kunitz-type protease inhibitor 5 II (SA5 II)
Length = 62
Score = 75.9 bits (185), Expect = 3e-14
Identities = 31/52 (59%), Positives = 37/52 (71%)
Frame = +3
Query: 45 ECSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIECRARC 200
+C LPK VG CR FPRY+YN+ + +CE+FIYGGC GN NNF T EC C
Sbjct: 4 DCELPKVVGPCRARFPRYYYNSSSKRCEKFIYGGCGGNANNFHTLEECEKVC 55
>sp|Q9TWF8|KC3_ANESU Kunitz-type kalicludine 3 (AsKC3)
Length = 59
Score = 75.5 bits (184), Expect = 4e-14
Identities = 31/52 (59%), Positives = 36/52 (69%)
Frame = +3
Query: 45 ECSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIECRARC 200
+C LPK VG CR FPRY+YN + +CE+FIYGGC GN NNF T EC C
Sbjct: 4 DCELPKVVGRCRARFPRYYYNLSSRRCEKFIYGGCGGNANNFHTLEECEKVC 55
>sp|O54819|TFPI1_MOUSE Tissue factor pathway inhibitor precursor (TFPI)
(Lipoprotein-associated coagulation inhibitor) (LACI)
(Extrinsic pathway inhibitor) (EPI)
Length = 306
Score = 74.3 bits (181), Expect = 8e-14
Identities = 29/53 (54%), Positives = 39/53 (73%)
Frame = +3
Query: 48 CSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIECRARCEH 206
C L ++ G+CRGY RY YN +T +CE+F+YGGC GN+NNF T EC+ CE+
Sbjct: 121 CFLEEDPGLCRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKICEN 173
Score = 59.7 bits (143), Expect = 2e-09
Identities = 23/51 (45%), Positives = 33/51 (64%)
Frame = +3
Query: 48 CSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIECRARC 200
C++ + G C+ YF+N T +CE+FIYGGC+GN+N F T EC+ C
Sbjct: 50 CAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTC 100
Score = 58.9 bits (141), Expect = 3e-09
Identities = 24/54 (44%), Positives = 32/54 (59%)
Frame = +3
Query: 42 PECSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIECRARCE 203
P C P + G+C+ R++YN+ TGKC +F Y GC GN NNF T C C+
Sbjct: 223 PWCLQPADSGLCKASERRFYYNSATGKCHRFNYTGCGGNNNNFTTRRRCLRSCK 276
>sp|Q9TWF9|KC2_ANESU Kunitz-type kalicludine 2 (AsKC2)
Length = 58
Score = 74.3 bits (181), Expect = 8e-14
Identities = 29/52 (55%), Positives = 37/52 (71%)
Frame = +3
Query: 45 ECSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIECRARC 200
+C LP +VG CR PRY+YN+ + +CE+FIYGGC+GN NNF T EC C
Sbjct: 4 DCLLPMDVGRCRARHPRYYYNSSSRRCEKFIYGGCRGNANNFITKKECEKVC 55
>sp|P82968|MCPI_MELCP Protease inhibitor (McaPI)
Length = 197
Score = 74.3 bits (181), Expect = 8e-14
Identities = 33/60 (55%), Positives = 41/60 (68%)
Frame = +3
Query: 21 HLSECKEPECSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIECRARC 200
H EC CSL K VG CRG F RY++++ +GKCE+F+YGGC GN NNF T C+ RC
Sbjct: 137 HPGECDA--CSLKKVVGPCRGAFRRYYFDSVSGKCEEFVYGGCGGNDNNFKTLDACQKRC 194
>sp|P00993|IBP_CARCR Chelonianin (Basic protease inhibitor) (RTPI)
Length = 110
Score = 74.3 bits (181), Expect = 8e-14
Identities = 32/55 (58%), Positives = 35/55 (63%)
Frame = +3
Query: 36 KEPECSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIECRARC 200
K C LP E G C+G PRYFYN + CE FIYGGC+GNKNNF T EC C
Sbjct: 4 KRDICRLPPEQGPCKGRIPRYFYNPASRMCESFIYGGCKGNKNNFKTKAECVRAC 58
>sp|P10646|TFPI1_HUMAN Tissue factor pathway inhibitor precursor (TFPI)
(Lipoprotein-associated coagulation inhibitor) (LACI)
(Extrinsic pathway inhibitor) (EPI)
Length = 304
Score = 73.6 bits (179), Expect = 1e-13
Identities = 33/65 (50%), Positives = 42/65 (64%)
Frame = +3
Query: 9 ILAIHLSECKEPECSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIEC 188
I+ L + K C L ++ G+CRGY RYFYN +T +CE+F YGGC GN NNF T EC
Sbjct: 112 IIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEEC 171
Query: 189 RARCE 203
+ CE
Sbjct: 172 KNICE 176
Score = 58.2 bits (139), Expect = 6e-09
Identities = 22/51 (43%), Positives = 33/51 (64%)
Frame = +3
Query: 48 CSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIECRARC 200
C+ + G C+ R+F+N T +CE+FIYGGC+GN+N F + EC+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
Score = 57.0 bits (136), Expect = 1e-08
Identities = 23/52 (44%), Positives = 31/52 (59%)
Frame = +3
Query: 48 CSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIECRARCE 203
C P + G+CR R++YN+ GKC F Y GC GN+NNF + EC C+
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
>sp|P81547|AXP1_ANTAF Kunitz-type proteinase inhibitor AXPI-I
Length = 58
Score = 73.6 bits (179), Expect = 1e-13
Identities = 29/52 (55%), Positives = 37/52 (71%)
Frame = +3
Query: 45 ECSLPKEVGMCRGYFPRYFYNTETGKCEQFIYGGCQGNKNNFFTPIECRARC 200
+C LPK+VG CR PR++YN+++GKCE F YGGC N NNF T EC+ C
Sbjct: 6 DCLLPKKVGPCRAAVPRFYYNSDSGKCEGFTYGGCHANANNFKTKDECKNAC 57
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,081,059
Number of Sequences: 369166
Number of extensions: 465143
Number of successful extensions: 1106
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1060
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1103
length of database: 68,354,980
effective HSP length: 53
effective length of database: 58,564,025
effective search space used: 1698356725
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)