Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_003_A23 (822 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P67962|KC1A_CHICK Casein kinase I, alpha isoform (CKI-al... 410 e-114 sp|P48729|KC1A_HUMAN Casein kinase I, alpha isoform (CKI-al... 410 e-114 sp|P67829|KC1A_SHEEP Casein kinase I, alpha isoform (CKI-al... 410 e-114 sp|P97633|KC1A_RAT Casein kinase I, alpha isoform (CKI-alph... 409 e-114 sp|P42168|YKL1_CAEEL Putative casein kinase I C03C10.1 in c... 406 e-113 sp|Q8N752|KC1AL_HUMAN Casein kinase I, alpha-like isoform (... 392 e-109 sp|P54367|KC1A_DROME Casein kinase I, alpha isoform (CKI-al... 374 e-103 sp|P40235|HHP1_SCHPO Casein kinase I homolog hhp1 363 e-100 sp|Q06486|KC1D_RAT Casein kinase I, delta isoform (CKI-delt... 361 1e-99 sp|P48730|KC1D_HUMAN Casein kinase I, delta isoform (CKI-de... 361 1e-99
>sp|P67962|KC1A_CHICK Casein kinase I, alpha isoform (CKI-alpha) (CK1) sp|P67963|KC1A_XENLA Casein kinase I, alpha isoform (CKI-alpha) (CK1) Length = 337 Score = 410 bits (1055), Expect = e-114 Identities = 193/247 (78%), Positives = 220/247 (89%) Frame = +2 Query: 77 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 256 +F+V K++LVRKIGSGSFGDIYL + ++NGEEVAVKLES ARHPQLLYESK+YK LQ Sbjct: 10 EFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQG 69 Query: 257 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 436 GVGIP IRWYG + YN LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E+ Sbjct: 70 GVGIPHIRWYGQE---KDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEY 126 Query: 437 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 616 +H+KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTAR Sbjct: 127 VHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTAR 186 Query: 617 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIE 796 YASINAH GIEQSRRDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK STP+E Sbjct: 187 YASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVE 246 Query: 797 VLCKSFP 817 VLCK FP Sbjct: 247 VLCKGFP 253
>sp|P48729|KC1A_HUMAN Casein kinase I, alpha isoform (CKI-alpha) (CK1) sp|Q8BK63|KC1A_MOUSE Casein kinase I, alpha isoform (CKI-alpha) (CK1) Length = 337 Score = 410 bits (1055), Expect = e-114 Identities = 193/247 (78%), Positives = 220/247 (89%) Frame = +2 Query: 77 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 256 +F+V K++LVRKIGSGSFGDIYL + ++NGEEVAVKLES ARHPQLLYESK+YK LQ Sbjct: 10 EFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQG 69 Query: 257 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 436 GVGIP IRWYG + YN LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E+ Sbjct: 70 GVGIPHIRWYGQE---KDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEY 126 Query: 437 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 616 +H+KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTAR Sbjct: 127 VHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTAR 186 Query: 617 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIE 796 YASINAH GIEQSRRDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK STP+E Sbjct: 187 YASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVE 246 Query: 797 VLCKSFP 817 VLCK FP Sbjct: 247 VLCKGFP 253
>sp|P67829|KC1A_SHEEP Casein kinase I, alpha isoform (CKI-alpha) (CK1) sp|P67828|KC1A_RABIT Casein kinase I, alpha isoform (CKI-alpha) (CK1) sp|P67827|KC1A_BOVIN Casein kinase I, alpha isoform (CKI-alpha) (CK1) Length = 325 Score = 410 bits (1055), Expect = e-114 Identities = 193/247 (78%), Positives = 220/247 (89%) Frame = +2 Query: 77 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 256 +F+V K++LVRKIGSGSFGDIYL + ++NGEEVAVKLES ARHPQLLYESK+YK LQ Sbjct: 10 EFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQG 69 Query: 257 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 436 GVGIP IRWYG + YN LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E+ Sbjct: 70 GVGIPHIRWYGQE---KDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEY 126 Query: 437 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 616 +H+KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTAR Sbjct: 127 VHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTAR 186 Query: 617 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIE 796 YASINAH GIEQSRRDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK STP+E Sbjct: 187 YASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVE 246 Query: 797 VLCKSFP 817 VLCK FP Sbjct: 247 VLCKGFP 253
>sp|P97633|KC1A_RAT Casein kinase I, alpha isoform (CKI-alpha) (CK1) Length = 325 Score = 409 bits (1052), Expect = e-114 Identities = 193/247 (78%), Positives = 219/247 (88%) Frame = +2 Query: 77 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 256 +F+V K++LVRKIGSGSFGDIYL + ++NGEEVAVKLES ARHPQLLYESK+YK LQ Sbjct: 10 EFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQG 69 Query: 257 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 436 GVGIP IRWYG YN LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E+ Sbjct: 70 GVGIPHIRWYGQG---KDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEY 126 Query: 437 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 616 +H+KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTGTAR Sbjct: 127 VHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTAR 186 Query: 617 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIE 796 YASINAH GIEQSRRDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK STP+E Sbjct: 187 YASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVE 246 Query: 797 VLCKSFP 817 VLCK FP Sbjct: 247 VLCKGFP 253
>sp|P42168|YKL1_CAEEL Putative casein kinase I C03C10.1 in chromosome III Length = 341 Score = 406 bits (1043), Expect = e-113 Identities = 191/247 (77%), Positives = 218/247 (88%) Frame = +2 Query: 77 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 256 DF+VA K++L+RKIGSGSFGDIY+ + V+NGEEVA+KLES ARHPQLLYESKVY+ LQ Sbjct: 9 DFIVATKYKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQG 68 Query: 257 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 436 GVGIP IRWYG + +YN LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM+ R+E+ Sbjct: 69 GVGIPHIRWYG---TEREYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIGRIEY 125 Query: 437 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 616 +H KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D++T+ HIPYREDKNLTGTAR Sbjct: 126 VHVKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTAR 185 Query: 617 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIE 796 YASINAH GIEQSRRDDMES+GYV MYF R TLPWQGLKA KKQKYE+I EKK +T +E Sbjct: 186 YASINAHLGIEQSRRDDMESLGYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTTSVE 245 Query: 797 VLCKSFP 817 LCK FP Sbjct: 246 HLCKGFP 252
>sp|Q8N752|KC1AL_HUMAN Casein kinase I, alpha-like isoform (CKI-alpha-like) (CK1) Length = 337 Score = 392 bits (1008), Expect = e-109 Identities = 183/247 (74%), Positives = 213/247 (86%) Frame = +2 Query: 77 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 256 + VV K++LVRKIGSGSFGD+YLG+ +NGEEVAVKLES +HPQLLYESK+Y LQ Sbjct: 10 ELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYESKLYTILQG 69 Query: 257 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 436 GVGIP + WYG + N LVMDLLGPSLEDLFNFC RRFTMKTVLMLA+QM++R+E+ Sbjct: 70 GVGIPHMHWYGQE---KDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEY 126 Query: 437 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 616 +H+KNF+HRDIKPDNFLMG GRHCNKLF++DFGL+KKY+D +T+ HIPYREDK+L GT R Sbjct: 127 VHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVR 186 Query: 617 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIE 796 YASINAH GIEQSRRDDMES+GYVFMYF R++LPWQGLKA KKQKYE+I EKK STP+E Sbjct: 187 YASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKKMSTPVE 246 Query: 797 VLCKSFP 817 VLCK FP Sbjct: 247 VLCKGFP 253
>sp|P54367|KC1A_DROME Casein kinase I, alpha isoform (CKI-alpha) (DmCK1) Length = 337 Score = 374 bits (961), Expect = e-103 Identities = 177/247 (71%), Positives = 210/247 (85%) Frame = +2 Query: 77 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 256 + +V K+R++RKIGSGSFGDIYLG+++ +GEEVA+K+ES +ARHPQLLYE+K+Y+ L Sbjct: 13 EIIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSG 72 Query: 257 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 436 GVG PRIR +G + +N LVMDLLGPSLEDLFNFC R FT+KTVLML +QM+ R+E+ Sbjct: 73 GVGFPRIRHHGKE---KNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEY 129 Query: 437 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 616 IH K FIHRDIKPDNFLMGIGRHCNKLF++DFGL+KK++D T+ HI YREDKNLTGTAR Sbjct: 130 IHLKCFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTAR 189 Query: 617 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIE 796 YASINAH GIEQSRRDDMES+GYV MYF R LPWQG+KAN K+QKYE+I EKK STPIE Sbjct: 190 YASINAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIE 249 Query: 797 VLCKSFP 817 VLCK P Sbjct: 250 VLCKGSP 256
>sp|P40235|HHP1_SCHPO Casein kinase I homolog hhp1 Length = 365 Score = 363 bits (932), Expect = e-100 Identities = 171/247 (69%), Positives = 208/247 (84%) Frame = +2 Query: 77 DFVVAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQD 256 D + K+R+ RKIGSGSFGDIYLG V +GEEVA+KLES A+HPQL YE +VY+ L Sbjct: 4 DLRIGNKYRIGRKIGSGSFGDIYLGTNVVSGEEVAIKLESTRAKHPQLEYEYRVYRILSG 63 Query: 257 GVGIPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEF 436 GVGIP +RW+G V+ YNA+VMDLLGPSLEDLFNFC R+F++KTVL+LA+Q+++R+EF Sbjct: 64 GVGIPFVRWFG---VECDYNAMVMDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEF 120 Query: 437 IHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTAR 616 IHSK+F+HRDIKPDNFLMGIG+ N++ ++DFGL+KKY+D KT HIPYRE+KNLTGTAR Sbjct: 121 IHSKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLAKKYRDHKTHLHIPYRENKNLTGTAR 180 Query: 617 YASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIE 796 YASIN H GIEQSRRDD+ES+GYV +YF R +LPWQGLKA KKQKYE+I EKK STP E Sbjct: 181 YASINTHLGIEQSRRDDLESLGYVLVYFCRGSLPWQGLKATTKKQKYEKIMEKKISTPTE 240 Query: 797 VLCKSFP 817 VLC+ FP Sbjct: 241 VLCRGFP 247
>sp|Q06486|KC1D_RAT Casein kinase I, delta isoform (CKI-delta) sp|Q9DC28|KC1D_MOUSE Casein kinase I, delta isoform (CKI-delta) (CKId) Length = 415 Score = 361 bits (927), Expect = 1e-99 Identities = 169/244 (69%), Positives = 205/244 (84%) Frame = +2 Query: 86 VAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQDGVG 265 V ++RL RKIGSGSFGDIYLG ++ GEEVA+KLE V +HPQL ESK+YK +Q GVG Sbjct: 5 VGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVG 64 Query: 266 IPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHS 445 IP IRW G +G YN +VM+LLGPSLEDLFNFC R+F++KTVL+LA+QM++R+E+IHS Sbjct: 65 IPTIRWCGAEG---DYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121 Query: 446 KNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYAS 625 KNFIHRD+KPDNFLMG+G+ N ++++DFGL+KKY+D +T HIPYRE+KNLTGTARYAS Sbjct: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYAS 181 Query: 626 INAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLC 805 IN H GIEQSRRDD+ES+GYV MYF +LPWQGLKA K+QKYERI EKK STPIEVLC Sbjct: 182 INTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLC 241 Query: 806 KSFP 817 K +P Sbjct: 242 KGYP 245
>sp|P48730|KC1D_HUMAN Casein kinase I, delta isoform (CKI-delta) (CKId) Length = 415 Score = 361 bits (927), Expect = 1e-99 Identities = 169/244 (69%), Positives = 205/244 (84%) Frame = +2 Query: 86 VAAKWRLVRKIGSGSFGDIYLGVAVSNGEEVAVKLESVNARHPQLLYESKVYKFLQDGVG 265 V ++RL RKIGSGSFGDIYLG ++ GEEVA+KLE V +HPQL ESK+YK +Q GVG Sbjct: 5 VGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVG 64 Query: 266 IPRIRWYGFDGVKNQYNALVMDLLGPSLEDLFNFCGRRFTMKTVLMLAEQMLTRVEFIHS 445 IP IRW G +G YN +VM+LLGPSLEDLFNFC R+F++KTVL+LA+QM++R+E+IHS Sbjct: 65 IPTIRWCGAEG---DYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121 Query: 446 KNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTGTARYAS 625 KNFIHRD+KPDNFLMG+G+ N ++++DFGL+KKY+D +T HIPYRE+KNLTGTARYAS Sbjct: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYAS 181 Query: 626 INAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRSTPIEVLC 805 IN H GIEQSRRDD+ES+GYV MYF +LPWQGLKA K+QKYERI EKK STPIEVLC Sbjct: 182 INTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLC 241 Query: 806 KSFP 817 K +P Sbjct: 242 KGYP 245
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 86,651,346 Number of Sequences: 369166 Number of extensions: 1722425 Number of successful extensions: 7478 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 6267 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6759 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7907893860 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)