Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_A14
(814 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P07688|CATB_BOVIN Cathepsin B precursor [Contains: Cathe... 395 e-110
sp|P07858|CATB_HUMAN Cathepsin B precursor (Cathepsin B1) (... 391 e-108
sp|P00787|CATB_RAT Cathepsin B precursor (Cathepsin B1) (RS... 384 e-106
sp|P10605|CATB_MOUSE Cathepsin B precursor (Cathepsin B1) [... 383 e-106
sp|P43233|CATB_CHICK Cathepsin B precursor (Cathepsin B1) [... 371 e-102
sp|P43157|CYSP_SCHJA Cathepsin B-like cysteine proteinase p... 348 1e-95
sp|P25792|CYSP_SCHMA Cathepsin B-like cysteine proteinase p... 337 2e-92
sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6... 317 2e-86
sp|P43509|CPR5_CAEEL Cathepsin B-like cysteine proteinase 5... 313 3e-85
sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precu... 308 9e-84
>sp|P07688|CATB_BOVIN Cathepsin B precursor [Contains: Cathepsin B light chain; Cathepsin
B heavy chain]
Length = 335
Score = 395 bits (1014), Expect = e-110
Identities = 174/253 (68%), Positives = 200/253 (79%)
Frame = +2
Query: 17 VRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAED 196
V LP +FDAR QWP C +I EIRDQ +CGSCWAFGAVEAI+DR CIHSNG +SAED
Sbjct: 78 VVLPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAED 137
Query: 197 LLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPN 376
+LTCCG CGDGCNGGFPSGAW++W GLV+GG Y +H+GC+ Y+ P C HHV G P
Sbjct: 138 MLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPP 197
Query: 377 CTGEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYA 556
CTGE TPKC K C+ GYS +Y EDK +G SSYSV +N++ IM EI NGPVE AFSVY+
Sbjct: 198 CTGEGDTPKCNKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYS 257
Query: 557 DFPSYKSGVYQHVSGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSD 736
DF YKSGVYQHVSG ++GGHAI+ILGWGVEN TPYWLV NSWN WGDNG+FKILRG D
Sbjct: 258 DFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQD 317
Query: 737 ECGIEDEVVAGIP 775
CGIE E+VAG+P
Sbjct: 318 HCGIESEIVAGMP 330
>sp|P07858|CATB_HUMAN Cathepsin B precursor (Cathepsin B1) (APP secretase) (APPS)
[Contains: Cathepsin B light chain; Cathepsin B heavy
chain]
Length = 339
Score = 391 bits (1004), Expect = e-108
Identities = 171/254 (67%), Positives = 203/254 (79%)
Frame = +2
Query: 17 VRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAED 196
++LP +FDAR QWP+C +I EIRDQ +CGSCWAFGAVEAI+DR CIH+N + +SAED
Sbjct: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137
Query: 197 LLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPN 376
LLTCCG CGDGCNGG+P+ AW++W GLV+GG Y +H+GC+ Y+ P C HHV G P
Sbjct: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197
Query: 377 CTGEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYA 556
CTGE TPKC K C+ GYS TY +DK YG +SYSV ++++ IM EI NGPVE AFSVY+
Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 257
Query: 557 DFPSYKSGVYQHVSGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSD 736
DF YKSGVYQHV+G M+GGHAI+ILGWGVEN TPYWLVANSWN WGDNG+FKILRG D
Sbjct: 258 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQD 317
Query: 737 ECGIEDEVVAGIPK 778
CGIE EVVAGIP+
Sbjct: 318 HCGIESEVVAGIPR 331
>sp|P00787|CATB_RAT Cathepsin B precursor (Cathepsin B1) (RSG-2) [Contains: Cathepsin B
light chain; Cathepsin B heavy chain]
Length = 339
Score = 384 bits (985), Expect = e-106
Identities = 163/254 (64%), Positives = 199/254 (78%)
Frame = +2
Query: 17 VRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAED 196
+ LP +FDAR QW C +I +IRDQ +CGSCWAFGAVEA++DR CIH+NG +SAED
Sbjct: 78 INLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAED 137
Query: 197 LLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPN 376
LLTCCG +CGDGCNGG+PSGAW++W GLV+GG Y +H+GC Y P C HHV G P
Sbjct: 138 LLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPP 197
Query: 377 CTGEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYA 556
CTGE TPKC K C+AGYS +Y EDK YG +SYSV +++ IM EI NGPVE AF+V++
Sbjct: 198 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFS 257
Query: 557 DFPSYKSGVYQHVSGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSD 736
DF +YKSGVY+H +G ++GGHAI+ILGWG+EN PYWLVANSWN WGDNG+FKILRG +
Sbjct: 258 DFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGEN 317
Query: 737 ECGIEDEVVAGIPK 778
CGIE E+VAGIP+
Sbjct: 318 HCGIESEIVAGIPR 331
>sp|P10605|CATB_MOUSE Cathepsin B precursor (Cathepsin B1) [Contains: Cathepsin B light
chain; Cathepsin B heavy chain]
Length = 339
Score = 383 bits (984), Expect = e-106
Identities = 165/254 (64%), Positives = 199/254 (78%)
Frame = +2
Query: 17 VRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAED 196
+ LP TFDAR QW C +IG+IRDQ +CGSCWAFGAVEAI+DR CIH+NG +SAED
Sbjct: 78 IDLPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAED 137
Query: 197 LLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPN 376
LLTCCG +CGDGCNGG+PSGAW +W GLV+GG Y +H+GC Y P C HHV G P
Sbjct: 138 LLTCCGIQCGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCLPYTIPPCEHHVNGSRPP 197
Query: 377 CTGEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYA 556
CTGE TP+C K+C+AGYS +Y EDK +G +SYSV ++ + IM EI NGPVE AF+V++
Sbjct: 198 CTGEGDTPRCNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVEGAFTVFS 257
Query: 557 DFPSYKSGVYQHVSGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSD 736
DF +YKSGVY+H +G M+GGHAI+ILGWGVEN PYWL ANSWN WGDNG+FKILRG +
Sbjct: 258 DFLTYKSGVYKHEAGDMMGGHAIRILGWGVENGVPYWLAANSWNLDWGDNGFFKILRGEN 317
Query: 737 ECGIEDEVVAGIPK 778
CGIE E+VAGIP+
Sbjct: 318 HCGIESEIVAGIPR 331
>sp|P43233|CATB_CHICK Cathepsin B precursor (Cathepsin B1) [Contains: Cathepsin B light
chain; Cathepsin B heavy chain]
Length = 340
Score = 371 bits (953), Expect = e-102
Identities = 163/254 (64%), Positives = 191/254 (75%), Gaps = 1/254 (0%)
Frame = +2
Query: 23 LPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAEDLL 202
LP TFD R QWP C +I EIRDQ +CGSCWAFGAVEAI+DR C+H+N + +SAEDLL
Sbjct: 80 LPDTFDTRKQWPNCPTISEIRDQGSCGSCWAFGAVEAISDRICVHTNAKVSVEVSAEDLL 139
Query: 203 TCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCT 382
+CCGF CG GCNGG+PSGAW YW GLV+GG Y +H+GC+ Y P C HHV G P CT
Sbjct: 140 SCCGFECGMGCNGGYPSGAWRYWTERGLVSGGLYDSHVGCRAYTIPPCEHHVNGSRPPCT 199
Query: 383 GEF-PTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYAD 559
GE TP+C + C+ GYS +Y EDK YG +SY V +++ IM EI NGPVE AF VY D
Sbjct: 200 GEGGETPRCSRHCEPGYSPSYKEDKHYGITSYGVPRSEKEIMAEIYKNGPVEGAFIVYED 259
Query: 560 FPSYKSGVYQHVSGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSDE 739
F YKSGVYQHVSG +GGHAI+ILGWGVEN TPYWL ANSWN WG G+FKILRG D
Sbjct: 260 FLMYKSGVYQHVSGEQVGGHAIRILGWGVENGTPYWLAANSWNTDWGITGFFKILRGEDH 319
Query: 740 CGIEDEVVAGIPKL 781
CGIE E+VAG+P++
Sbjct: 320 CGIESEIVAGVPRM 333
>sp|P43157|CYSP_SCHJA Cathepsin B-like cysteine proteinase precursor (Antigen Sj31)
Length = 342
Score = 348 bits (893), Expect = 1e-95
Identities = 152/255 (59%), Positives = 189/255 (74%), Gaps = 1/255 (0%)
Frame = +2
Query: 17 VRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAED 196
V +P+ FD+R +WP CKSI +IRDQS CGSCWAFGAVEA+TDR CI S G Q+ +SA D
Sbjct: 88 VEIPSQFDSRKKWPHCKSISQIRDQSRCGSCWAFGAVEAMTDRICIQSGGGQSAELSALD 147
Query: 197 LLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPN 376
L++CC CGDGC GGFP AW YWV G+VTGG H GCQ Y FPKC HH G YP
Sbjct: 148 LISCCK-DCGDGCQGGFPGVAWDYWVKRGIVTGGSKENHTGCQPYPFPKCEHHTKGKYPA 206
Query: 377 C-TGEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVY 553
C T + TP+CK+ CQ GY Y +DK YG SY+V +N++ I ++I+ GPVEAAF VY
Sbjct: 207 CGTKIYKTPQCKQTCQKGYKTPYEQDKHYGDESYNVQNNEKVIQRDIMMYGPVEAAFDVY 266
Query: 554 ADFPSYKSGVYQHVSGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGS 733
DF +YKSG+Y+HV+G ++GGHAI+I+GWGVE TPYWL+ANSWN WG+ G F+++RG
Sbjct: 267 EDFLNYKSGIYRHVTGSIVGGHAIRIIGWGVEKRTPYWLIANSWNEDWGEKGLFRMVRGR 326
Query: 734 DECGIEDEVVAGIPK 778
DEC IE +VVAG+ K
Sbjct: 327 DECSIESDVVAGLIK 341
>sp|P25792|CYSP_SCHMA Cathepsin B-like cysteine proteinase precursor (Antigen Sm31)
Length = 340
Score = 337 bits (864), Expect = 2e-92
Identities = 148/252 (58%), Positives = 185/252 (73%), Gaps = 1/252 (0%)
Frame = +2
Query: 17 VRLPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAED 196
V +P+ FD+R +WP CKSI IRDQS CGSCW+FGAVEA++DR CI S G Q +SA D
Sbjct: 87 VEIPSNFDSRKKWPGCKSIATIRDQSRCGSCWSFGAVEAMSDRSCIQSGGKQNVELSAVD 146
Query: 197 LLTCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPN 376
LLTCC CG GC GG AW YWV +G+VT H GC+ Y FPKC HH G YP
Sbjct: 147 LLTCCE-SCGLGCEGGILGPAWDYWVKEGIVTASSKENHTGCEPYPFPKCEHHTKGKYPP 205
Query: 377 CTGE-FPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVY 553
C + + TP+CK+ CQ Y Y +DK GKSSY+V ++++AI +EI+ GPVEA+F+VY
Sbjct: 206 CGSKIYNTPRCKQTCQRKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEASFTVY 265
Query: 554 ADFPSYKSGVYQHVSGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGS 733
DF +YKSG+Y+H++G LGGHAI+I+GWGVEN TPYWL+ANSWN WG+NGYF+I+RG
Sbjct: 266 EDFLNYKSGIYKHITGEALGGHAIRIIGWGVENKTPYWLIANSWNEDWGENGYFRIVRGR 325
Query: 734 DECGIEDEVVAG 769
DEC IE EV+AG
Sbjct: 326 DECSIESEVIAG 337
>sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6 precursor (Cysteine
protease-related 6)
Length = 379
Score = 317 bits (812), Expect = 2e-86
Identities = 145/258 (56%), Positives = 185/258 (71%), Gaps = 5/258 (1%)
Frame = +2
Query: 23 LPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAEDLL 202
+P +FD+R WPKC SI IRDQS+CGSCWAFGAVEA++DR CI S+G +SA+DLL
Sbjct: 105 IPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDLL 164
Query: 203 TCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHV----IGPY 370
+CC CG GCNGG P AW YWV DG+VTG Y A+ GC+ Y FP C HH P
Sbjct: 165 SCCK-SCGFGCNGGDPLAAWRYWVKDGIVTGSNYTANNGCKPYPFPPCEHHSKKTHFDPC 223
Query: 371 PNCTGEFPTPKCKKACQAGYS-KTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFS 547
P+ +PTPKC+K C + Y+ KTY+EDK +G S+Y V + +AI +E++T+GP+E AF
Sbjct: 224 PHDL--YPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAFE 281
Query: 548 VYADFPSYKSGVYQHVSGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKILR 727
VY DF +Y GVY H G + GGHA+K++GWG+++ PYW VANSWN WG++G+F+ILR
Sbjct: 282 VYEDFLNYDGGVYVHTGGKLGGGHAVKLIGWGIDDGIPYWTVANSWNTDWGEDGFFRILR 341
Query: 728 GSDECGIEDEVVAGIPKL 781
G DECGIE VV GIPKL
Sbjct: 342 GVDECGIESGVVGGIPKL 359
>sp|P43509|CPR5_CAEEL Cathepsin B-like cysteine proteinase 5 precursor (Cysteine
protease-related 5)
Length = 344
Score = 313 bits (803), Expect = 3e-85
Identities = 145/259 (55%), Positives = 177/259 (68%), Gaps = 6/259 (2%)
Frame = +2
Query: 23 LPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAEDLL 202
+P FDAR QWP C SI IRDQS+CGSCWAF A EAI+DR CI SNG +S+EDLL
Sbjct: 82 IPDHFDARDQWPNCMSINNIRDQSDCGSCWAFAAAEAISDRTCIASNGAVNTLLSSEDLL 141
Query: 203 TCCG--FRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIG-PYP 373
+CC F CG+GC GG+P AW +WV GLVTGG Y GC+ Y+ C V G +P
Sbjct: 142 SCCTGMFSCGNGCEGGYPIQAWKWWVKHGLVTGGSYETQFGCKPYSIAPCGETVNGVKWP 201
Query: 374 NCTGEF-PTPKCKKACQA--GYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAF 544
C + PTPKC +C + Y+ Y +DK +G ++Y+V + I EILTNGP+E AF
Sbjct: 202 ACPEDTEPTPKCVDSCTSKNNYATPYLQDKHFGSTAYAVGKKVEQIQTEILTNGPIEVAF 261
Query: 545 SVYADFPSYKSGVYQHVSGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKIL 724
+VY DF Y +GVY H +G LGGHA+KILGWGV+N TPYWLVANSWN WG+ GYF+I+
Sbjct: 262 TVYEDFYQYTTGVYVHTAGASLGGHAVKILGWGVDNGTPYWLVANSWNVAWGEKGYFRII 321
Query: 725 RGSDECGIEDEVVAGIPKL 781
RG +ECGIE VAGIP L
Sbjct: 322 RGLNECGIEHSAVAGIPDL 340
>sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precursor
Length = 329
Score = 308 bits (790), Expect = 9e-84
Identities = 143/253 (56%), Positives = 176/253 (69%)
Frame = +2
Query: 23 LPTTFDARVQWPKCKSIGEIRDQSNCGSCWAFGAVEAITDRYCIHSNGTQTPRISAEDLL 202
+P TFD+R QW +CKSI IRDQ+ CGSCWAFGA E I+DR CI + G Q P IS +DLL
Sbjct: 85 VPATFDSRTQWSECKSIKLIRDQATCGSCWAFGAAEMISDRTCIETKGAQQPIISPDDLL 144
Query: 203 TCCGFRCGDGCNGGFPSGAWHYWVTDGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCT 382
+CCG CG+GC GG+P A +W + G+VTGG+Y GC+ Y C+ NC
Sbjct: 145 SCCGSSCGNGCEGGYPIQALRWWDSKGVVTGGDYHG-AGCKPYPIAPCTSG------NCP 197
Query: 383 GEFPTPKCKKACQAGYSKTYAEDKQYGKSSYSVDSNQQAIMQEILTNGPVEAAFSVYADF 562
E TP C +CQ+GYS YA+DK +G S+Y+V N +I EI NGPVEAAFSVY DF
Sbjct: 198 -ESKTPSCSMSCQSGYSTAYAKDKHFGVSAYAVPKNAASIQAEIYANGPVEAAFSVYEDF 256
Query: 563 PSYKSGVYQHVSGGMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDNGYFKILRGSDEC 742
YKSGVY+H +G LGGHAIKI+GWG E+ +PYWLVANSW WG++G+FKI RG D+C
Sbjct: 257 YKYKSGVYKHTAGKYLGGHAIKIIGWGTESGSPYWLVANSWGVNWGESGFFKIYRGDDQC 316
Query: 743 GIEDEVVAGIPKL 781
GIE VVAG K+
Sbjct: 317 GIESAVVAGKAKV 329
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,036,435
Number of Sequences: 369166
Number of extensions: 2380512
Number of successful extensions: 7347
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6594
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7105
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7763237265
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)