Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_A12
(847 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P20488|SYPH_BOVIN Synaptophysin (Major synaptic vesicle ... 138 2e-32
sp|P08247|SYPH_HUMAN Synaptophysin (Major synaptic vesicle ... 136 8e-32
sp|Q8TBG9|SYNPR_HUMAN Synaptoporin 134 4e-31
sp|P22831|SYNPR_RAT Synaptoporin 134 4e-31
sp|P07825|SYPH_RAT Synaptophysin (Major synaptic vesicle pr... 133 5e-31
sp|Q62277|SYPH_MOUSE Synaptophysin (Major synaptic vesicle ... 133 5e-31
sp|Q8BGN8|SYNPR_MOUSE Synaptoporin 133 7e-31
sp|O09117|SYPL_MOUSE Synaptophysin-like protein (Pantophysin) 119 1e-26
sp|Q5VXT5|SYPL2_HUMAN Synaptophysin-like protein 2 115 2e-25
sp|Q16563|SYPL_HUMAN Synaptophysin-like protein (Pantophysin) 114 3e-25
>sp|P20488|SYPH_BOVIN Synaptophysin (Major synaptic vesicle protein p38)
Length = 313
Score = 138 bits (347), Expect = 2e-32
Identities = 66/162 (40%), Positives = 92/162 (56%), Gaps = 1/162 (0%)
Frame = +1
Query: 4 LRVNYSYPFNINGSNKNIEICSKANREAIVYGNYSSQSQFFVFVGVIAMLYCLAAIILYV 183
+ V + YPF ++ C ++ + GNYSS ++FFV V V A LY + A+ Y+
Sbjct: 67 IEVEFEYPFRLHEVYFEAPTCQGDPKKIFLVGNYSSSAEFFVTVAVFAFLYSMGALATYI 126
Query: 184 FFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILGIEYCTST 363
F +N++ P +DF+ TAV A +W + S AWA G+S +KM TDP II G+ C
Sbjct: 127 FLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKGMHVCHQP 186
Query: 364 GK-CKASLYGSYGGLNASLIAGFANIALWAANLWFLFKETLW 486
G CK GLN S++ GF N+ LW NLWF+FKET W
Sbjct: 187 GNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGW 228
>sp|P08247|SYPH_HUMAN Synaptophysin (Major synaptic vesicle protein p38)
Length = 313
Score = 136 bits (342), Expect = 8e-32
Identities = 65/162 (40%), Positives = 92/162 (56%), Gaps = 1/162 (0%)
Frame = +1
Query: 4 LRVNYSYPFNINGSNKNIEICSKANREAIVYGNYSSQSQFFVFVGVIAMLYCLAAIILYV 183
+ V + YPF ++ + C + + G+YSS ++FFV V V A LY + A+ Y+
Sbjct: 67 IEVEFEYPFRLHQVYFDAPTCRGGTTKVFLVGDYSSSAEFFVTVAVFAFLYSMGALATYI 126
Query: 184 FFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILGIEYCTST 363
F +N++ P +DF+ TAV A +W + S AWA G+S +KM TDP II + C T
Sbjct: 127 FLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPVCRQT 186
Query: 364 GK-CKASLYGSYGGLNASLIAGFANIALWAANLWFLFKETLW 486
G CK GLN S++ GF N+ LW NLWF+FKET W
Sbjct: 187 GNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGW 228
>sp|Q8TBG9|SYNPR_HUMAN Synaptoporin
Length = 265
Score = 134 bits (336), Expect = 4e-31
Identities = 65/162 (40%), Positives = 98/162 (60%), Gaps = 2/162 (1%)
Frame = +1
Query: 10 VNYSYPFNINGSNKNIEICSKANREAI-VYGNYSSQSQFFVFVGVIAMLYCLAAIILYVF 186
+ ++YPF ++ + C R+ + + G+ SS ++FFV V V A LY LAA ++Y+F
Sbjct: 43 IAFAYPFRLHQVTFEVPTCEGKERQKLALIGDSSSSAEFFVTVAVFAFLYSLAATVVYIF 102
Query: 187 FSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILGIEYCTS-T 363
F +N+R P IDFI+T V + LW + S AWA G+S +K+ TDP +++L + C +
Sbjct: 103 FQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPS 162
Query: 364 GKCKASLYGSYGGLNASLIAGFANIALWAANLWFLFKETLWY 489
KC A LN S++ GF N LWA N+WF+FKET W+
Sbjct: 163 NKCMAIHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWH 204
>sp|P22831|SYNPR_RAT Synaptoporin
Length = 265
Score = 134 bits (336), Expect = 4e-31
Identities = 65/162 (40%), Positives = 98/162 (60%), Gaps = 2/162 (1%)
Frame = +1
Query: 10 VNYSYPFNINGSNKNIEICSKANREAI-VYGNYSSQSQFFVFVGVIAMLYCLAAIILYVF 186
+ ++YPF ++ + C R+ + + G+ SS ++FFV V V A LY LAA ++Y+F
Sbjct: 43 IAFAYPFRLHQVTFEVPTCEGKERQKLALVGDSSSSAEFFVTVAVFAFLYSLAATVVYIF 102
Query: 187 FSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILGIEYCTS-T 363
F +N+R P IDFI+T V + LW + S AWA G+S +K+ TDP +++L + C +
Sbjct: 103 FQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPS 162
Query: 364 GKCKASLYGSYGGLNASLIAGFANIALWAANLWFLFKETLWY 489
KC A LN S++ GF N LWA N+WF+FKET W+
Sbjct: 163 NKCMAVHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWH 204
>sp|P07825|SYPH_RAT Synaptophysin (Major synaptic vesicle protein p38)
Length = 307
Score = 133 bits (335), Expect = 5e-31
Identities = 67/163 (41%), Positives = 93/163 (57%), Gaps = 2/163 (1%)
Frame = +1
Query: 4 LRVNYSYPFNINGSNKNIEICSKANREAI-VYGNYSSQSQFFVFVGVIAMLYCLAAIILY 180
+ V + YPF ++ + C K I + G+YSS ++FFV V V A LY + A+ Y
Sbjct: 61 IEVEFEYPFRLHQVYFDAPSCVKGGTTKIFLVGDYSSSAEFFVTVAVFAFLYSMGALATY 120
Query: 181 VFFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILGIEYCTS 360
+F +N++ P +DF+ TAV A +W + S AWA G+S +KM TDP II + C
Sbjct: 121 IFLQNKYRENNKGPMMDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPMCRQ 180
Query: 361 TGK-CKASLYGSYGGLNASLIAGFANIALWAANLWFLFKETLW 486
TG CK GLN S++ GF N+ LW NLWF+FKET W
Sbjct: 181 TGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGW 223
>sp|Q62277|SYPH_MOUSE Synaptophysin (Major synaptic vesicle protein p38) (BM89 antigen)
Length = 314
Score = 133 bits (335), Expect = 5e-31
Identities = 67/163 (41%), Positives = 93/163 (57%), Gaps = 2/163 (1%)
Frame = +1
Query: 4 LRVNYSYPFNINGSNKNIEICSKANREAI-VYGNYSSQSQFFVFVGVIAMLYCLAAIILY 180
+ V + YPF ++ + C K I + G+YSS ++FFV V V A LY + A+ Y
Sbjct: 67 IEVEFEYPFRLHQVYFDAPSCVKGGTTKIFLVGDYSSSAEFFVTVAVFAFLYSMGALATY 126
Query: 181 VFFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILGIEYCTS 360
+F +N++ P +DF+ TAV A +W + S AWA G+S +KM TDP II + C
Sbjct: 127 IFLQNKYRENNKGPMMDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPMCRQ 186
Query: 361 TGK-CKASLYGSYGGLNASLIAGFANIALWAANLWFLFKETLW 486
TG CK GLN S++ GF N+ LW NLWF+FKET W
Sbjct: 187 TGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGW 229
>sp|Q8BGN8|SYNPR_MOUSE Synaptoporin
Length = 265
Score = 133 bits (334), Expect = 7e-31
Identities = 65/162 (40%), Positives = 97/162 (59%), Gaps = 2/162 (1%)
Frame = +1
Query: 10 VNYSYPFNINGSNKNIEICS-KANREAIVYGNYSSQSQFFVFVGVIAMLYCLAAIILYVF 186
+ ++YPF + + C K ++ + G+ SS ++FFV V V A LY LAA ++Y+F
Sbjct: 43 IAFAYPFRLQQVTFEVPTCEGKEQQKLALVGDSSSSAEFFVTVAVFAFLYSLAATVVYIF 102
Query: 187 FSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILGIEYCTS-T 363
F +N+R P IDFI+T V + LW + S AWA G+S +K+ TDP +++L + C +
Sbjct: 103 FQNKYRENNRGPLIDFIVTVVFSFLWLVGSSAWAKGLSDVKVATDPKEVLLLMSACKQPS 162
Query: 364 GKCKASLYGSYGGLNASLIAGFANIALWAANLWFLFKETLWY 489
KC A LN S++ GF N LWA N+WF+FKET W+
Sbjct: 163 NKCMAVHSPVMSSLNTSVVFGFLNFILWAGNIWFVFKETGWH 204
>sp|O09117|SYPL_MOUSE Synaptophysin-like protein (Pantophysin)
Length = 261
Score = 119 bits (298), Expect = 1e-26
Identities = 61/170 (35%), Positives = 96/170 (56%), Gaps = 6/170 (3%)
Frame = +1
Query: 16 YSYPFNINGSN----KNIEICSKANREAIVYGNYSSQSQFFVFVGVIAMLYCLAAIILYV 183
+ YPF +N ++ N+ +C + ++ G+YSS +QF+V V LYC+AA++LYV
Sbjct: 79 FGYPFRLNQASFHTPPNVSVCDVNWEKHVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYV 138
Query: 184 FFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILGIEYCT-- 357
++ + + ++P IDFI+T V LW + S AWA ++ +K+ T +I+ +E C
Sbjct: 139 GYTNLYRDSRKLPMIDFIVTLVATFLWLVSSSAWAKALTDIKVATG-HRIVEELEICNPE 197
Query: 358 STGKCKASLYGSYGGLNASLIAGFANIALWAANLWFLFKETLWYERRNPS 507
S C S G LN S+I GF N+ LW N WF++KET + N S
Sbjct: 198 SGVSCYFVSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTS 247
>sp|Q5VXT5|SYPL2_HUMAN Synaptophysin-like protein 2
Length = 272
Score = 115 bits (287), Expect = 2e-25
Identities = 52/171 (30%), Positives = 91/171 (53%), Gaps = 3/171 (1%)
Frame = +1
Query: 10 VNYSYPFNINGSNKNIEICSKANREAIVY--GNYSSQSQFFVFVGVIAMLYCLAAIILYV 183
V + YPF ++ + +C + + ++ G++S+ ++FFV +G+ + Y +AA+++Y+
Sbjct: 78 VAFGYPFRLHRIQYEMPLCDEESSSKTMHLMGDFSAPAEFFVTLGIFSFFYTMAALVIYL 137
Query: 184 FFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILGIEYC-TS 360
F + +N R P +DF +T W + + AW G++ +K T P+ + + C
Sbjct: 138 RFHNLYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGE 197
Query: 361 TGKCKASLYGSYGGLNASLIAGFANIALWAANLWFLFKETLWYERRNPSDQ 513
C A S G N S++ GF N LWA N WF+FKET W+ + DQ
Sbjct: 198 EAVCSAGATPSMGLANISVLFGFINFFLWAGNCWFVFKETPWHGQGQGQDQ 248
>sp|Q16563|SYPL_HUMAN Synaptophysin-like protein (Pantophysin)
Length = 259
Score = 114 bits (285), Expect = 3e-25
Identities = 58/169 (34%), Positives = 93/169 (55%), Gaps = 5/169 (2%)
Frame = +1
Query: 16 YSYPFNINGSN----KNIEICSKANREAIVYGNYSSQSQFFVFVGVIAMLYCLAAIILYV 183
+ YPF +N ++ + IC ++ ++ G+YSS +QF+V V LYC+AA++LYV
Sbjct: 78 FGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYV 137
Query: 184 FFSEMSFQNDRIPKIDFIITAVIAILWFICSVAWADGVSKLKMYTDPAKIILGIEYCTST 363
++ + + ++P IDF++T V LW + + AWA ++ +K+ T II + C
Sbjct: 138 GYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNIIDELPPCKKK 196
Query: 364 G-KCKASLYGSYGGLNASLIAGFANIALWAANLWFLFKETLWYERRNPS 507
C S G LN S+I GF N+ LW N WF++KET + N S
Sbjct: 197 AVLCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTS 245
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,703,907
Number of Sequences: 369166
Number of extensions: 1899125
Number of successful extensions: 4565
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4416
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4551
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8293644780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)