Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_A10
(848 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q13573|SNW1_HUMAN Nuclear protein SkiP (Ski-interacting ... 260 4e-69
sp|Q9CSN1|SNW1_MOUSE Nuclear protein SkiP (Ski-interacting ... 258 2e-68
sp|P39736|BX42_DROME Puff-specific protein Bx42 247 3e-65
sp|Q22836|YGH1_CAEEL Hypothetical protein T27F2.1 in chromo... 201 2e-51
sp|Q09882|PRP45_SCHPO Pre-mRNA splicing factor prp45 (Compl... 176 6e-44
sp|Q759B6|PRP45_ASHGO Pre-mRNA splicing factor PRP45 (Pre-m... 122 1e-27
sp|P54705|SNWA_DICDI Protein snwA 119 1e-26
sp|P28004|PRP45_YEAST Pre-mRNA splicing factor PRP45 (Pre-m... 80 5e-15
sp|Q8SX83|SPEN_DROME Split ends protein 43 0.001
sp|P22793|TRHY_SHEEP Trichohyalin 42 0.003
>sp|Q13573|SNW1_HUMAN Nuclear protein SkiP (Ski-interacting protein) (SNW1 protein)
(Nuclear receptor coactivator NCoA-62)
Length = 536
Score = 260 bits (664), Expect = 4e-69
Identities = 132/283 (46%), Positives = 191/283 (67%), Gaps = 8/283 (2%)
Frame = +1
Query: 13 FVLYTPAQKGPLFNNGNQQRIIKMVEVQIDPMEPPKFQINKKIPRGXXXXXXXXXXXXXX 192
++ YTP+Q+G FN+G +QR+I+MVE+Q DPMEPP+F+INKKIPRG
Sbjct: 176 YIRYTPSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSR 235
Query: 193 XXTKREKAMWKIPPCVSNWKNPRGYTVPLANRVAADGRNNQVTGSNEKINSFSEALFIAE 372
T +E+ WKIPPC+SNWKN +GYT+PL R+AADGR Q NE +EAL+IA+
Sbjct: 236 KMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIAD 295
Query: 373 RKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQ---NMATEEDSLEAKERDEI 543
RK+RE + R + +K+ QKEK+K++ KLR+ A K RE++ E++ EA+ERDEI
Sbjct: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEI 355
Query: 544 RHDRQRIRNRERNMNKAGPEVRRKVL--EDRDISEQIALGQANPLLNRLKDDNVYDRRLM 717
RHDR++ R +RN+++A P+ R K+ E+RDISE IALG NP R ++ YD+RL
Sbjct: 356 RHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNP---RTSNEVQYDQRLF 412
Query: 718 DKTGGLDSGFLAGEDEMYNIYDKPL---FNQNKSVYKAPRHTD 837
+++ G+DSGF GEDE+YN+YD+ + +S+Y+ ++ D
Sbjct: 413 NQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLD 455
>sp|Q9CSN1|SNW1_MOUSE Nuclear protein SkiP (Ski-interacting protein) (SNW1 protein)
Length = 536
Score = 258 bits (658), Expect = 2e-68
Identities = 130/283 (45%), Positives = 191/283 (67%), Gaps = 8/283 (2%)
Frame = +1
Query: 13 FVLYTPAQKGPLFNNGNQQRIIKMVEVQIDPMEPPKFQINKKIPRGXXXXXXXXXXXXXX 192
++ YTP+Q+G FN+G +QR+I+MVE+Q +PMEPP+F+INKKIPRG
Sbjct: 176 YIRYTPSQQGVAFNSGAKQRVIRMVEMQKEPMEPPRFKINKKIPRGPPSPPAPVMHSPSR 235
Query: 193 XXTKREKAMWKIPPCVSNWKNPRGYTVPLANRVAADGRNNQVTGSNEKINSFSEALFIAE 372
T +E+ WKIPPC+SNWKN +GYT+P+ R+AADGR Q NE +EAL+IA+
Sbjct: 236 KMTVKEQQEWKIPPCISNWKNAKGYTIPIDKRLAADGRGLQTVHINENFAKLAEALYIAD 295
Query: 373 RKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQ---NMATEEDSLEAKERDEI 543
RK+RE + R + +K+ QKEK+K++ KLR+ A K RE++ E++ EA+ERDEI
Sbjct: 296 RKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEI 355
Query: 544 RHDRQRIRNRERNMNKAGPEVRRKVL--EDRDISEQIALGQANPLLNRLKDDNVYDRRLM 717
RHDR++ R +RN+++A P+ R K+ E+RDISE IALG NP R ++ YD+RL
Sbjct: 356 RHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNP---RTSNEVQYDQRLF 412
Query: 718 DKTGGLDSGFLAGEDEMYNIYDKPL---FNQNKSVYKAPRHTD 837
+++ G+DSGF GEDE+YN+YD+ + +S+Y+ ++ D
Sbjct: 413 NQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLD 455
>sp|P39736|BX42_DROME Puff-specific protein Bx42
Length = 547
Score = 247 bits (631), Expect = 3e-65
Identities = 133/291 (45%), Positives = 186/291 (63%), Gaps = 15/291 (5%)
Frame = +1
Query: 13 FVLYTPAQKGPLFNNGNQQRIIKMVEVQIDPMEPPKFQINKKIPRGXXXXXXXXXXXXXX 192
++ YTP+Q+G FN+G +QR+I+MVE Q+DPMEPPKF+INKKIPRG
Sbjct: 179 YIRYTPSQQGDTFNSGAKQRVIRMVEAQLDPMEPPKFRINKKIPRGPPSPPAPVLHSPSR 238
Query: 193 XXTKREKAMWKIPPCVSNWKNPRGYTVPLANRVAADGRNNQVTGSNEKINSFSEALFIAE 372
T +E+ WKIPPC+SNWKN +GYT+PL R+AADGR Q NEK +EAL+IA+
Sbjct: 239 KVTVKEQKEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQQVHINEKFAKMAEALYIAD 298
Query: 373 RKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREK----QNMATEEDS------LE 522
RK+RE + R+ L +KL QKEK+K + LR A + RE+ +N E S E
Sbjct: 299 RKAREAVEARSQLEKKLAQKEKEKKEDMLRMMAQRAREERAGLRNPEAAEPSGSGATGSE 358
Query: 523 AKERDEIRHDRQRIRNRERNMNKAGPEVRRKVLE--DRDISEQIALGQANPLLNRLKDDN 696
+ER+++R +RQR R R+RN+ +A PE R K+ + +RDISEQIALG P + +
Sbjct: 359 VRERNDLRAERQRERQRDRNLQRAAPEKRSKLQKERERDISEQIALGL--PAKSAGNGET 416
Query: 697 VYDRRLMDKTGGLDSGFLAGEDEMYNIYDKPLFNQN---KSVYKAPRHTDS 840
++D+RL + T G+DSG+ G+DE YN+YDKP + N +Y+ + DS
Sbjct: 417 LFDQRLFNTTKGMDSGY--GDDEAYNVYDKPWRDSNTLGAHIYRPSKQADS 465
>sp|Q22836|YGH1_CAEEL Hypothetical protein T27F2.1 in chromosome V
Length = 535
Score = 201 bits (511), Expect = 2e-51
Identities = 113/262 (43%), Positives = 164/262 (62%), Gaps = 5/262 (1%)
Frame = +1
Query: 13 FVLYTPAQKGPLFNNGNQQRIIKMVEVQIDPMEPPKFQINKKIPRGXXXXXXXXXXXXXX 192
++ YTP+Q+ G+QQRII+MVE Q DPMEPPKF+IN+KIPR
Sbjct: 181 YIRYTPSQQNGAA--GSQQRIIRMVEEQKDPMEPPKFKINQKIPRAPPSPPAPVMHSPPR 238
Query: 193 XXTKREKAMWKIPPCVSNWKNPRGYTVPLANRVAADGRNNQVTGSNEKINSFSEALFIAE 372
T +++ WKIPPC+SNWKNP+G+TV L R+AADGR Q T NE ++AL+IA+
Sbjct: 239 KMTAKDQNDWKIPPCISNWKNPKGFTVGLDKRLAADGRGLQQTHINENFAKLADALYIAD 298
Query: 373 RKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQN---MATEEDSLEAKERDEI 543
RK+REE+ R L +++ Q +K + +AK+ + A K R++++ +ED + K R+EI
Sbjct: 299 RKAREEVETRAQLERRVAQNKKSEQEAKMAEAAAKARQERSAMRRKDDEDDEQVKVREEI 358
Query: 544 RHDRQRIRNRERNMNKAGPEVRRKVLE--DRDISEQIALGQANPLLNRLKDDNVYDRRLM 717
R DR +ERN+ ++ P+ K+ + +RDISE+I LG + R + +D+RL
Sbjct: 359 RRDRLDDIRKERNIARSRPDKADKLRKERERDISEKIVLGLPDTNQKRTGEPQ-FDQRLF 417
Query: 718 DKTGGLDSGFLAGEDEMYNIYD 783
DKT GLDSG A +D+ YN YD
Sbjct: 418 DKTQGLDSG--AMDDDTYNPYD 437
>sp|Q09882|PRP45_SCHPO Pre-mRNA splicing factor prp45 (Complexed with cdc5 protein 13) (Cell
cycle control protein cwf13) (Transcriptional coregulator
snw1)
Length = 557
Score = 176 bits (447), Expect = 6e-44
Identities = 113/325 (34%), Positives = 169/325 (52%), Gaps = 47/325 (14%)
Frame = +1
Query: 13 FVLYTPA-QKGPLFNNGNQQRIIKMVEVQIDPMEPPKFQINKKIPRGXXXXXXXXXXXXX 189
++ YTP+ Q G + +QRIIKMV + DPMEPPKF+ +KK+PRG
Sbjct: 183 YIRYTPSNQMGQALS---KQRIIKMVTAEQDPMEPPKFR-HKKVPRGPPSPPPPVLHSPP 238
Query: 190 XXXTKREKAMWKIPPCVSNWKNPRGYTVPLANRVAADGRNNQVTGSNEKINSFSEALFIA 369
+ +E+ W+IPP +SNWKNP+GYT+PL R+AADGR N+ FSEAL+
Sbjct: 239 RKVSAQEQQDWQIPPSISNWKNPKGYTIPLDKRLAADGRGLNDVEINDGFAKFSEALYTV 298
Query: 370 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREK---QNMAT------------ 504
ER++REE+ R ++RQK+ +KEK + + +L A K RE +N A+
Sbjct: 299 ERQAREEVRYRAIMRQKMAEKEKQEKEQRLFMLAQKAREDRMGRNAASSGPSHAKPRSTS 358
Query: 505 -----------------------EEDSLEAKERDEIRHDRQRIRNRERNMNKAGPEVRRK 615
+EDS + R E+R +R+R ++ +++ G E R K
Sbjct: 359 VSSEERSRSRAGSFSHHSESENEDEDSEAFRRRQELRRERRRQAEKDLRLSRMGAEKRAK 418
Query: 616 VLE---DRDISEQIALGQANPLLNRLKDDNVYDRRLMDKTGGLDSGFLAGEDEMYNIYDK 786
+ E RD++E++ALG + P + D + D RL ++ GL SGF +++ YN+YDK
Sbjct: 419 LAEKDRPRDVAERVALGLSKP---SMSSDTMIDSRLFNQASGLGSGF--QDEDSYNVYDK 473
Query: 787 PLFNQNKSVYKAP-----RHTDSSA 846
P S P R D+SA
Sbjct: 474 PWRAAPSSTLYRPGATLSRQVDASA 498
>sp|Q759B6|PRP45_ASHGO Pre-mRNA splicing factor PRP45 (Pre-mRNA processing protein 45)
Length = 443
Score = 122 bits (307), Expect = 1e-27
Identities = 91/276 (32%), Positives = 139/276 (50%), Gaps = 16/276 (5%)
Frame = +1
Query: 55 NGNQQRIIKMVEVQIDPMEPPKFQINKKIPRGXXXXXXXXXXXXXXXXTKREKAMWKIPP 234
N + RIIK+V+ DP++P + + K + TK ++ W+IP
Sbjct: 124 NKSTSRIIKIVDHVADPLQPSQIKRKKVVAPPTDEPVAPILHSATEKLTKEQREQWRIPS 183
Query: 235 CVSNWKNPRGYTVPLANRVAADGRNNQ----VTGSNEKINSFSEALFIAERKSREEISQR 402
VSNWKNP GY + L R+A DGR N+ + NEK+ + AL AE K+REE+ R
Sbjct: 184 AVSNWKNPNGYAIDLEKRIAIDGRYNREGTAIPAVNEKLLELTNALEEAESKAREEVRNR 243
Query: 403 NLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERDEIRHDRQRIRNRERN 582
R++ +++ + KLR+ A + RE++ + ++ +E DE RQ RN +R+
Sbjct: 244 AEARKQEAEQQVRLKEDKLRELAQRSREERQRKRRQ-PIDHEEYDESAIIRQTERNEKRD 302
Query: 583 -------MNKAGPEVRRKVL---EDRDISEQIALGQANPLLNRLKDDNVYDRRLMDKTGG 732
++K R +VL + RD+SE+I LG A P + + D + YD RL+ K G
Sbjct: 303 QMKNDMRLSKLSTADRLRVLAHAQGRDVSEKIILGAAKP--SEVPDVH-YDSRLLTKGAG 359
Query: 733 LDSGFLAGEDEMYNIYDKPLFNQN--KSVYKAPRHT 834
+ G E +YD PLF QN +YK R T
Sbjct: 360 T---AVPGAPE--QVYDGPLFAQNAMDRLYKPARFT 390
>sp|P54705|SNWA_DICDI Protein snwA
Length = 685
Score = 119 bits (298), Expect = 1e-26
Identities = 69/204 (33%), Positives = 114/204 (55%), Gaps = 3/204 (1%)
Frame = +1
Query: 13 FVLYTPA-QKGPLFNNGN--QQRIIKMVEVQIDPMEPPKFQINKKIPRGXXXXXXXXXXX 183
++ YTP+ Q G NNG+ +I++MV+V DP+EPPK++I KKI
Sbjct: 196 YIKYTPSNQLGS--NNGSALNSKIVRMVDVAQDPLEPPKYKIKKKIME-HGSPPAPVMHS 252
Query: 184 XXXXXTKREKAMWKIPPCVSNWKNPRGYTVPLANRVAADGRNNQVTGSNEKINSFSEALF 363
+ +++ W IPPCVSNWKNP+G+ + + R+ ++G Q N+K F++AL+
Sbjct: 253 PTRKLSVQDQQDWTIPPCVSNWKNPKGFAISIDKRLVSNGGGLQDVEINDKFAHFTQALY 312
Query: 364 IAERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERDEI 543
IAE +REE+S R L +KL QKEK++ LR+ A VR +++ ++ K+ +
Sbjct: 313 IAESNAREEVSARAELERKLAQKEKERKQDMLRKLAEDVRNERSGIIQQ-RYTRKDNSDS 371
Query: 544 RHDRQRIRNRERNMNKAGPEVRRK 615
+D + + + NK P + R+
Sbjct: 372 DNDNDNDSSSDEDKNKRTPPMNRR 395
Score = 80.5 bits (197), Expect = 5e-15
Identities = 52/163 (31%), Positives = 90/163 (55%), Gaps = 14/163 (8%)
Frame = +1
Query: 373 RKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAK-------- 528
R SR+ R+ + N+ + ++D+ R K R + ++ DS +++
Sbjct: 455 RDSRDNRDSRDSRDNRDNRDNRRRDDSNDRDRYSKRRSDSDSDSDSDSSDSEDERVRRER 514
Query: 529 ----ERDEIRHDRQRIRNRERNMNKAGPEVRRKVLEDRDISEQIALGQANPLLNRLKDDN 696
ERD+IR +++R RE + +G + + +DRDISE+IALGQA+ + +D+
Sbjct: 515 KEKLERDKIRMEKKRELEREYRLEASGKKSKFNRDQDRDISEKIALGQAS---IKRTEDS 571
Query: 697 VYDRRLMDKTGGLDSGFLAGEDEMYNIYDKPLFN--QNKSVYK 819
+YD+RL +++ L SGF G D+ YN+Y KPLF + S+Y+
Sbjct: 572 IYDQRLFNQSESLTSGF--GNDDSYNVYSKPLFGGAVSNSIYR 612
>sp|P28004|PRP45_YEAST Pre-mRNA splicing factor PRP45 (Pre-mRNA processing protein 45)
Length = 379
Score = 80.5 bits (197), Expect = 5e-15
Identities = 68/207 (32%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Frame = +1
Query: 220 WKIPPCVSNWKNPRGYTVPLANRV--AADGRNNQVTGSNEKINSFSEALFIAERKSREEI 393
WKIP VSNWKNP GYTV L RV A D NN + N+ SEAL A++K+R+EI
Sbjct: 163 WKIPAAVSNWKNPNGYTVALERRVGKALDNENNTI---NDGFMKLSEALENADKKARQEI 219
Query: 394 SQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERDEIRHDRQRIRNR 573
+ L++ ++E ++KL++ L R + + T + K +
Sbjct: 220 RSKMELKRLAMEQEMLAKESKLKE--LSQRARYHNGTPQTGAIVKPK------------- 264
Query: 574 ERNMNKAGPEVRRKVL---EDRDISEQIALGQANPLLNRLKDDNVYDRRLMDKTGGLDSG 744
+ R K L + RD+SE+I LG A + D YD R T G ++
Sbjct: 265 ----KQTSTVARLKELAYSQGRDVSEKIILGAAK---RSEQPDLQYDSRFF--TRGANAS 315
Query: 745 FLAGEDEMYNIYDKPLFNQN--KSVYK 819
ED+ +YD PLF Q +S+YK
Sbjct: 316 AKRHEDQ---VYDNPLFVQQDIESIYK 339
>sp|Q8SX83|SPEN_DROME Split ends protein
Length = 5560
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/109 (28%), Positives = 55/109 (50%), Gaps = 17/109 (15%)
Frame = +1
Query: 370 ERKSREEISQRNLLRQ--------KLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEA 525
E+K R+E +++L +Q K Q+E++K D K ++ K RE++ A E+ +
Sbjct: 1926 EKKERQEKREKDLRKQVEREEKDRKAQQEEREKEDRKAKEEE-KEREREKKAQEDREKKE 1984
Query: 526 KERDEIRHDRQR--------IRNRE-RNMNKAGPEVRRKVLEDRDISEQ 645
+E E+R QR IR ++ R + + R K L D+D+ E+
Sbjct: 1985 REERELREKEQRDKEQKEKEIREKDLREKEQRERDNREKELRDKDLREK 2033
Score = 41.2 bits (95), Expect = 0.004
Identities = 35/115 (30%), Positives = 62/115 (53%), Gaps = 1/115 (0%)
Frame = +1
Query: 370 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERDEIRH 549
+RK++EE +R R+K Q++++K + + R+ +REK+ E+ E +E+D +R
Sbjct: 1960 DRKAKEEEKERE--REKKAQEDREKKEREERE----LREKEQRDKEQKEKEIREKD-LRE 2012
Query: 550 DRQRIR-NRERNMNKAGPEVRRKVLEDRDISEQIALGQANPLLNRLKDDNVYDRR 711
QR R NRE+ E+R K L ++++ E+ Q L+R KD + R
Sbjct: 2013 KEQRERDNREK-------ELRDKDLREKEMREK---EQREKELHREKDQREREHR 2057
Score = 37.0 bits (84), Expect = 0.069
Identities = 28/124 (22%), Positives = 55/124 (44%)
Frame = +1
Query: 370 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERDEIRH 549
E+K REE R ++ QKEK+ + LR+ + R+ + + L KE E +
Sbjct: 1981 EKKEREERELREKEQRDKEQKEKEIREKDLREKEQRERDNREKELRDKDLREKEMRE-KE 2039
Query: 550 DRQRIRNRERNMNKAGPEVRRKVLEDRDISEQIALGQANPLLNRLKDDNVYDRRLMDKTG 729
R++ +RE++ + + + D+ ++ G R+++ + Y + MD G
Sbjct: 2040 QREKELHREKDQREREHREKEQSRRAMDVEQEGRGG-------RMRELSSYQKSKMDIAG 2092
Query: 730 GLDS 741
S
Sbjct: 2093 EASS 2096
Score = 33.1 bits (74), Expect = 1.00
Identities = 24/121 (19%), Positives = 58/121 (47%)
Frame = +1
Query: 283 NRVAADGRNNQVTGSNEKINSFSEALFIAERKSREEISQRNLLRQKLNQKEKDKNDAKLR 462
N ++D R N T + K + +E + +++N +K ++ ++K + LR
Sbjct: 1880 NASSSDKRKNSSTSQSSKSATPRIEDDSSEADDTADKAEKNQRHEKEKKERQEKREKDLR 1939
Query: 463 QYALKVREKQNMATEEDSLEAKERDEIRHDRQRIRNRERNMNKAGPEVRRKVLEDRDISE 642
+ RE+++ +++ E ++R +++R R + KA + +K E+R++ E
Sbjct: 1940 KQV--EREEKDRKAQQEEREKEDRKAKEEEKEREREK-----KAQEDREKKEREERELRE 1992
Query: 643 Q 645
+
Sbjct: 1993 K 1993
>sp|P22793|TRHY_SHEEP Trichohyalin
Length = 1549
Score = 41.6 bits (96), Expect = 0.003
Identities = 28/119 (23%), Positives = 59/119 (49%), Gaps = 14/119 (11%)
Frame = +1
Query: 331 EKINSFSEALFIAERKSREEISQRNLLRQKLNQKEKD--------KNDAKLRQYALKV-- 480
E++ E L +R+ R ++ +R L ++L Q+E + D + RQY KV
Sbjct: 721 ERLQREKEQLQREDREKRRQVRERKYLEEELQQEEDRLQREKQLLREDREKRQYLEKVEL 780
Query: 481 -REKQNMATEEDSLEAKER---DEIRHDRQRIRNRERNMNKAGPEVRRKVLEDRDISEQ 645
RE++ + E+ E + + +E+ + +R+ +E+ + + E RR+ +R + E+
Sbjct: 781 QREEEQLQREKRRQERERQYREEELLREEERLHRKEQQLQREECEKRRRQELERQLEEE 839
Score = 39.3 bits (90), Expect = 0.014
Identities = 33/116 (28%), Positives = 58/116 (50%), Gaps = 4/116 (3%)
Frame = +1
Query: 370 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERD-EIR 546
+RK REE ++L ++E+D+ K R+ E+Q + E+ L +ERD + R
Sbjct: 1022 DRKFREEEQLLQEREEQLRRQERDR---KFRE------EEQLLQEREEQLRRQERDRKFR 1072
Query: 547 HDRQRIRNRERNMNKAGPEVRRKVLED---RDISEQIALGQANPLLNRLKDDNVYD 705
+ Q++R ER + E RK E+ R+ EQ+ L + P L + +D ++
Sbjct: 1073 EEEQQLRLLERE-QQLRQERNRKFREEQLLREREEQLRLQEGEPQLRQKRDRKFHE 1127
Score = 37.4 bits (85), Expect = 0.053
Identities = 30/105 (28%), Positives = 54/105 (51%), Gaps = 13/105 (12%)
Frame = +1
Query: 370 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNM---------ATEEDSLE 522
+RK REE ++L ++E+D+ + +++ L+ RE+Q + + EE
Sbjct: 1320 DRKFREEEQLLKESEEQLRRQERDRKFHE-KEHLLREREEQQLRRQELEGVFSQEEQLRR 1378
Query: 523 AKERDEIRHDRQRIR---NRERNMNKAGPEVRRKVLE-DRDISEQ 645
A++ +E R RQR R E+++ + E +R+V E DR EQ
Sbjct: 1379 AEQEEEQRRQRQRDRKFLEEEQSLQREREEEKRRVQEQDRKFLEQ 1423
Score = 35.0 bits (79), Expect = 0.26
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 15/119 (12%)
Frame = +1
Query: 370 ERKSREEISQRNL------LRQKLNQKEKDKNDAKLRQYALKVRE---------KQNMAT 504
+RK REE Q L LRQ+ N+K +++ + R+ L+++E +
Sbjct: 1068 DRKFREEEQQLRLLEREQQLRQERNRKFREEQLLREREEQLRLQEGEPQLRQKRDRKFHE 1127
Query: 505 EEDSLEAKERDEIRHDRQRIRNRERNMNKAGPEVRRKVLEDRDISEQIALGQANPLLNR 681
EE L+ +E R +R R E + K E R+ DR E+ L Q L R
Sbjct: 1128 EEQLLQEREEQLRRQERDRKFREEAQILKEREEQLRRQERDRKFREEEQLLQEREELRR 1186
Score = 33.5 bits (75), Expect = 0.76
Identities = 26/118 (22%), Positives = 53/118 (44%), Gaps = 5/118 (4%)
Frame = +1
Query: 370 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERDEIRH 549
E + EE QR + + ++EK + + +QY KV EE+ L+ +ER++ R
Sbjct: 420 ELQREEERLQREEEQLQREEREKRRRQEREKQYLEKVE-----LWEEEQLQREEREKRRQ 474
Query: 550 DR-----QRIRNRERNMNKAGPEVRRKVLEDRDISEQIALGQANPLLNRLKDDNVYDR 708
+R +++ RE + +R+ +R E++ L + L ++ +R
Sbjct: 475 EREKQYLEKVELREEEQLQRQEREKRRQERERQYLEKVELQEEEQLQREEREKRRQER 532
Score = 33.5 bits (75), Expect = 0.76
Identities = 22/86 (25%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Frame = +1
Query: 370 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERD-EIR 546
+RK REE ++L ++E+D+ K RE++ + E + L +ER+ ++R
Sbjct: 1145 DRKFREEAQILKEREEQLRRQERDR----------KFREEEQLLQEREELRRQEREPQLR 1194
Query: 547 HDRQRIRNRERNMNKAGPEVRRKVLE 624
+R R E + + ++RR+ E
Sbjct: 1195 QERDRKFREEEQLLQEREKLRRQERE 1220
Score = 33.1 bits (74), Expect = 1.00
Identities = 22/74 (29%), Positives = 42/74 (56%), Gaps = 4/74 (5%)
Frame = +1
Query: 352 EALFIAERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMAT----EEDSL 519
E L ER+ R + ++ L +K+ +E+++ + RQ + REKQ + EE+ L
Sbjct: 546 EQLQRQEREKRRQEREKQYL-EKVELQEEEQLQRQERQKRRQEREKQYLEKVELQEEEQL 604
Query: 520 EAKERDEIRHDRQR 561
+ +ER++ R +R+R
Sbjct: 605 QRQEREKRRQERER 618
Score = 33.1 bits (74), Expect = 1.00
Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 8/106 (7%)
Frame = +1
Query: 331 EKINSFSEALFIAERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVR--------E 486
E+ F E R+ +EE+ +R L Q+ +E+ + K R+ ++R E
Sbjct: 1415 EQDRKFLEQEEQLHREEQEELRRRQQLDQQYRAEEQFAREEKRRRQEQELRQEEQRRRQE 1474
Query: 487 KQNMATEEDSLEAKERDEIRHDRQRIRNRERNMNKAGPEVRRKVLE 624
++ EE+ L ++++E + ++R + R + RR+VLE
Sbjct: 1475 RERKFREEEQLRRQQQEEQKRRQERDVQQSRRQVWEEDKGRRQVLE 1520
Score = 32.3 bits (72), Expect = 1.7
Identities = 19/72 (26%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = +1
Query: 367 AERKSREEISQRNLLRQKLN-QKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERDEI 543
A+R+ E Q L +KL +K + + + + R+ L+ RE++ + EE+ L+ +ER++
Sbjct: 385 AQREQVREEEQLRLKEEKLQREKRRQERERQYREVELQ-REEERLQREEEQLQREEREKR 443
Query: 544 RHDRQRIRNRER 579
R + + E+
Sbjct: 444 RRQEREKQYLEK 455
Score = 32.3 bits (72), Expect = 1.7
Identities = 23/123 (18%), Positives = 56/123 (45%), Gaps = 9/123 (7%)
Frame = +1
Query: 331 EKINSFSEALFIAERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMAT-- 504
EK+ + E E + + + +K+ +E+++ + R+ + RE+Q +
Sbjct: 454 EKVELWEEEQLQREEREKRRQEREKQYLEKVELREEEQLQRQEREKRRQERERQYLEKVE 513
Query: 505 --EEDSLEAKERDEIRHDRQR-----IRNRERNMNKAGPEVRRKVLEDRDISEQIALGQA 663
EE+ L+ +ER++ R +R+R + +E + +R+ ++ E++ L +
Sbjct: 514 LQEEEQLQREEREKRRQERERQYLEKVELQEEEQLQRQEREKRRQEREKQYLEKVELQEE 573
Query: 664 NPL 672
L
Sbjct: 574 EQL 576
Score = 32.3 bits (72), Expect = 1.7
Identities = 28/122 (22%), Positives = 56/122 (45%), Gaps = 5/122 (4%)
Frame = +1
Query: 352 EALFIAERKSREEISQRNLLR----QKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSL 519
E L ER+ R + +R L Q+ Q ++++ + + ++ + EK+ + +E+ L
Sbjct: 664 EQLLREEREKRRQERERQYLEKVELQEEEQLQREEREKRRQERERQYLEKEELQRQEERL 723
Query: 520 EAKERDEIRHDRQRIRNRERNMNKAGPEVR-RKVLEDRDISEQIALGQANPLLNRLKDDN 696
+ ++ R DR++ R +VR RK LE+ E+ L + LL ++
Sbjct: 724 QREKEQLQREDREKRR-----------QVRERKYLEEELQQEEDRLQREKQLLREDREKR 772
Query: 697 VY 702
Y
Sbjct: 773 QY 774
Score = 31.6 bits (70), Expect = 2.9
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Frame = +1
Query: 370 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERDEIRH 549
+RK REE ++L ++E+D+ K R+ E+Q + E+ L +ERD H
Sbjct: 1297 DRKFREEEQLLQEREEQLRRQERDR---KFRE------EEQLLKESEEQLRRQERDRKFH 1347
Query: 550 DRQR-IRNRERNMNKAGPEVRRKVLE 624
+++ +R RE ++RR+ LE
Sbjct: 1348 EKEHLLREREEQ------QLRRQELE 1367
Score = 30.8 bits (68), Expect = 5.0
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 10/102 (9%)
Frame = +1
Query: 370 ERKSREEISQRNLLR----QKLNQKEKDKNDAKLRQYALKVREKQNMATEED-----SLE 522
ER+ R+ + LL+ +K+ E+D+ + Q ++ +Q + E D L
Sbjct: 935 ERRDRKFREEEQLLKGQREEKIRYLEEDRKFREEEQQLRRLEREQQLRQERDRKFREELS 994
Query: 523 AKERD-EIRHDRQRIRNRERNMNKAGPEVRRKVLEDRDISEQ 645
+ERD + R + Q ++ RE + + E RK E+ + ++
Sbjct: 995 RQERDRKFREEEQLLQEREEQLRR--QERDRKFREEEQLLQE 1034
Score = 30.4 bits (67), Expect = 6.5
Identities = 30/127 (23%), Positives = 54/127 (42%), Gaps = 14/127 (11%)
Frame = +1
Query: 352 EALFIAERKSREEISQRNLLR--------QKLNQKEKDKNDAKLRQYALKVREKQN-MAT 504
E L ER+ R + +R L Q Q+ + + + RQY K ++Q
Sbjct: 602 EQLQRQEREKRRQERERQYLEKVELQEEEQVQRQEREKRRQERERQYLEKELQRQEERLQ 661
Query: 505 EEDSLEAKERDEIRHDRQR-----IRNRERNMNKAGPEVRRKVLEDRDISEQIALGQANP 669
EE+ L +ER++ R +R+R + +E + +R+ +R E+ L +
Sbjct: 662 EEEQLLREEREKRRQERERQYLEKVELQEEEQLQREEREKRRQERERQYLEKEELQRQEE 721
Query: 670 LLNRLKD 690
L R K+
Sbjct: 722 RLQREKE 728
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.313 0.131 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,827,833
Number of Sequences: 369166
Number of extensions: 1529965
Number of successful extensions: 5186
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4362
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4894
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8341863645
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)