Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_P13
(823 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9WYG0|Y325_THEMA Hypothetical oxidoreductase TM0325 64 7e-10
sp|P55541|Y4LA_RHISN Putative short-chain type dehydrogenas... 60 9e-09
sp|P37769|KDUD_ECOLI 2-deoxy-D-gluconate 3-dehydrogenase (2... 59 2e-08
sp|P33368|YOHF_ECOLI Hypothetical oxidoreductase yohF 58 4e-08
sp|Q56318|Y019_THEMA Putative oxidoreductase TM0019 57 5e-08
sp|Q45219|Y2146_BRAJA Probable short-chain type dehydrogena... 55 2e-07
sp|Q12634|T4HR_MAGGR Tetrahydroxynaphthalene reductase (T4H... 55 2e-07
sp|Q56840|HCDR_XANP2 2-(R)-hydroxypropyl-CoM dehydrogenase ... 54 7e-07
sp|Q29529|CBR2_PIG Lung carbonyl reductase [NADPH] (NADPH-d... 53 1e-06
sp|Q05528|KDUD_ERWCH 2-deoxy-D-gluconate 3-dehydrogenase (2... 53 1e-06
>sp|Q9WYG0|Y325_THEMA Hypothetical oxidoreductase TM0325
Length = 251
Score = 63.5 bits (153), Expect = 7e-10
Identities = 36/114 (31%), Positives = 58/114 (50%)
Frame = +2
Query: 11 TIKVFGRIDILVNNASAISLTNTNDTMMKTYDLMNSINARGTYLCSKLCIPHIAKSGPGG 190
T++ FGR+DILVNNA + N +T + +D ++N +G +L SK + + K G GG
Sbjct: 74 TVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLLSKYAVEQMKKQG-GG 132
Query: 191 HVVNISPPLNMSAKWFQNHVAYTMSKFGMSMCVLGMAEELKSKNIAVNALWPKT 352
+VN+S + Y++SK + +A + I VNA+ P T
Sbjct: 133 VIVNVSSEAGLIG--IPRRCVYSVSKAALLGLTRSLAVDYVDYGIRVNAVCPGT 184
>sp|P55541|Y4LA_RHISN Putative short-chain type dehydrogenase/reductase Y4LA
Length = 278
Score = 59.7 bits (143), Expect = 9e-09
Identities = 40/112 (35%), Positives = 58/112 (51%), Gaps = 4/112 (3%)
Frame = +2
Query: 23 FGRIDILVNNASAISLTNTN----DTMMKTYDLMNSINARGTYLCSKLCIPHIAKSGPGG 190
FG +D+LVNNASA+ LT + D + +D + N RGT LC + IP + G GG
Sbjct: 81 FGGVDLLVNNASAMHLTPRDRAILDLDLAVWDQTMATNLRGTLLCCRQAIPRMIARG-GG 139
Query: 191 HVVNISPPLNMSAKWFQNHVAYTMSKFGMSMCVLGMAEELKSKNIAVNALWP 346
+VN+S +S Q +Y +SK M+M +A + I NA+ P
Sbjct: 140 AIVNMSSCQGLSGDTAQ--TSYAVSKAAMNMLSASLATQYGHAQIRCNAVAP 189
>sp|P37769|KDUD_ECOLI 2-deoxy-D-gluconate 3-dehydrogenase (2-keto-3-deoxygluconate
oxidoreductase)
Length = 253
Score = 58.5 bits (140), Expect = 2e-08
Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 3/111 (2%)
Frame = +2
Query: 23 FGRIDILVNNASAISLTNTNDTMMKTYDLMNSINARGTYLCSKLCIPHIAKSGPGGHVVN 202
FG IDILVNNA I + + K +D + ++N + + S+ H G GG ++N
Sbjct: 83 FGHIDILVNNAGLIRREDALEFSEKDWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIIN 142
Query: 203 ISPPLNMSAKWFQNHV---AYTMSKFGMSMCVLGMAEELKSKNIAVNALWP 346
I+ L+ FQ + +YT SK G+ MA E NI VNA+ P
Sbjct: 143 IASMLS-----FQGGIRVPSYTASKSGVMGVTRLMANEWAKHNINVNAIAP 188
>sp|P33368|YOHF_ECOLI Hypothetical oxidoreductase yohF
Length = 253
Score = 57.8 bits (138), Expect = 4e-08
Identities = 35/111 (31%), Positives = 56/111 (50%)
Frame = +2
Query: 14 IKVFGRIDILVNNASAISLTNTNDTMMKTYDLMNSINARGTYLCSKLCIPHIAKSGPGGH 193
I+ GRID+LVNNA A++ D + + +++ G +LCS++ + K G GG
Sbjct: 75 IQRLGRIDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQIAARQMVKQGQGGR 134
Query: 194 VVNISPPLNMSAKWFQNHVAYTMSKFGMSMCVLGMAEELKSKNIAVNALWP 346
++NI+ + + AYT +K + MA EL I VNA+ P
Sbjct: 135 IINITSVHEHTP--LPDASAYTAAKHALGGLTKAMALELVRHKILVNAVAP 183
>sp|Q56318|Y019_THEMA Putative oxidoreductase TM0019
Length = 256
Score = 57.4 bits (137), Expect = 5e-08
Identities = 33/115 (28%), Positives = 64/115 (55%), Gaps = 3/115 (2%)
Frame = +2
Query: 11 TIKVFGRIDILVNNASAISLTNTNDTMMKTYDLMNSINARGTYLCSKLCIPHIAKSGPGG 190
T++++G +D+LVNNA+ +S+ + + ++ ++ + +N G Y+CS+ C + K G GG
Sbjct: 75 TVEIYGGVDVLVNNAAVMSVKSIFERPLEEWERVIRVNLTGPYICSRYCAEEMIKRG-GG 133
Query: 191 HVVNISPPLNMSAKWFQNH---VAYTMSKFGMSMCVLGMAEELKSKNIAVNALWP 346
++NI+ S + FQ+ Y+ SK G+ +A L +I V ++ P
Sbjct: 134 VIINIA-----STRAFQSEPDTEPYSASKGGLVALTHSLAVSLSRYHIRVVSISP 183
>sp|Q45219|Y2146_BRAJA Probable short-chain type dehydrogenase/reductase blr2146
Length = 281
Score = 55.5 bits (132), Expect = 2e-07
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 4/112 (3%)
Frame = +2
Query: 23 FGRIDILVNNASAISLTNTNDTMMK----TYDLMNSINARGTYLCSKLCIPHIAKSGPGG 190
FG +D+LVNNASA+ LT + +++ +D + N RGT LC + IP + G GG
Sbjct: 81 FGGVDLLVNNASAMHLTPRDRAILELELAVWDQTMATNLRGTLLCCRQAIPRMIARG-GG 139
Query: 191 HVVNISPPLNMSAKWFQNHVAYTMSKFGMSMCVLGMAEELKSKNIAVNALWP 346
+VN+S +S +Y SK M+M +A + I NA+ P
Sbjct: 140 AIVNMSSCQGLSGD--TALTSYAASKAAMNMLSSSLATQYGHAQIRCNAVAP 189
>sp|Q12634|T4HR_MAGGR Tetrahydroxynaphthalene reductase (T4HN reductase) (THNR)
Length = 283
Score = 55.1 bits (131), Expect = 2e-07
Identities = 36/135 (26%), Positives = 67/135 (49%), Gaps = 4/135 (2%)
Frame = +2
Query: 14 IKVFGRIDILVNNASAISLTNTNDTMMKTYDLMNSINARGTYLCSKLCIPHIAKSGPGGH 193
+K+FG++DI+ +N+ +S + D + +D + +IN RG + ++ H+ GG
Sbjct: 102 VKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFVAREAYKHLE---IGGR 158
Query: 194 VVNISPPLNMSAKWFQNHVAYTMSKFGMSMCVLGMAEELKSKNIAVNALWP---KTAIYT 364
++ + + AK H Y+ SK + MA ++ K I VN + P KT +Y
Sbjct: 159 LI-LMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADKKITVNVVAPGGIKTDMYH 217
Query: 365 A-AMEMLGGGKHIVN 406
A E + G+++ N
Sbjct: 218 AVCREYIPNGENLSN 232
>sp|Q56840|HCDR_XANP2 2-(R)-hydroxypropyl-CoM dehydrogenase (R-HPCDH) (Aliphatic epoxide
carboxylation component III)
Length = 250
Score = 53.5 bits (127), Expect = 7e-07
Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 3/115 (2%)
Frame = +2
Query: 11 TIKVFGRIDILVNNASAISLTNT---NDTMMKTYDLMNSINARGTYLCSKLCIPHIAKSG 181
T++ FG ID+LVNNA + + T ++ +D + ++N RG +L + +PH+ G
Sbjct: 74 TMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLGCRAVLPHMLLQG 133
Query: 182 PGGHVVNISPPLNMSAKWFQNHVAYTMSKFGMSMCVLGMAEELKSKNIAVNALWP 346
G +VNI+ ++ A F AYT SK + +A + I NA+ P
Sbjct: 134 -AGVIVNIASVASLVA--FPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRCNAVCP 185
>sp|Q29529|CBR2_PIG Lung carbonyl reductase [NADPH] (NADPH-dependent carbonyl
reductase) (LCR)
Length = 244
Score = 52.8 bits (125), Expect = 1e-06
Identities = 35/114 (30%), Positives = 58/114 (50%)
Frame = +2
Query: 26 GRIDILVNNASAISLTNTNDTMMKTYDLMNSINARGTYLCSKLCIPHIAKSGPGGHVVNI 205
G +D+LVNNA+ + DT + +D ++N R + S++ + + G G +VN+
Sbjct: 75 GPVDLLVNNAAVALMQPFLDTTKEVFDRSFNVNLRSVFQVSQIVARSMIERGVPGSIVNV 134
Query: 206 SPPLNMSAKWFQNHVAYTMSKFGMSMCVLGMAEELKSKNIAVNALWPKTAIYTA 367
S +S + AY+ +K M+M MA EL I VN++ P T + TA
Sbjct: 135 SS--MVSHVTYPGLAAYSSTKGAMTMLTKSMAMELGPHKIRVNSVNP-TVVLTA 185
>sp|Q05528|KDUD_ERWCH 2-deoxy-D-gluconate 3-dehydrogenase (2-keto-3-deoxygluconate
oxidoreductase)
Length = 253
Score = 52.8 bits (125), Expect = 1e-06
Identities = 35/111 (31%), Positives = 55/111 (49%), Gaps = 3/111 (2%)
Frame = +2
Query: 23 FGRIDILVNNASAISLTNTNDTMMKTYDLMNSINARGTYLCSKLCIPHIAKSGPGGHVVN 202
FG++DILVNNA I + + K +D + ++N + + S+ K G GG ++N
Sbjct: 83 FGKVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVFFMSQTVARQFIKQGHGGKIIN 142
Query: 203 ISPPLNMSAKWFQNHV---AYTMSKFGMSMCVLGMAEELKSKNIAVNALWP 346
I+ L+ FQ + +YT SK + +A E NI VNA+ P
Sbjct: 143 IASMLS-----FQGGIPVPSYTASKKRVMGITRIVANEWAKHNINVNAIAP 188
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,261,887
Number of Sequences: 369166
Number of extensions: 2233418
Number of successful extensions: 5735
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5546
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5706
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7907893860
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)