Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_P12
(625 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P58021|TM9S2_MOUSE Transmembrane 9 superfamily protein m... 247 2e-65
sp|Q66HG5|TM9S2_RAT Transmembrane 9 superfamily protein mem... 247 2e-65
sp|Q99805|TM9S2_HUMAN Transmembrane 9 superfamily protein m... 247 2e-65
sp|Q5R8Y6|TM9S2_PONPY Transmembrane 9 superfamily protein m... 247 2e-65
sp|Q92544|TM9S4_HUMAN Transmembrane 9 superfamily protein m... 199 4e-51
sp|P32802|EMP70_YEAST Endosomal P24A protein precursor (70 ... 156 5e-38
sp|Q9ET30|TM9S3_MOUSE Transmembrane 9 superfamily protein m... 136 5e-32
sp|Q9HD45|TM9S3_HUMAN Transmembrane 9 superfamily protein m... 136 5e-32
sp|O15321|TM9S1_HUMAN Transmembrane 9 superfamily protein m... 132 5e-31
sp|Q9DBU0|TM9S1_MOUSE Transmembrane 9 superfamily protein m... 132 5e-31
>sp|P58021|TM9S2_MOUSE Transmembrane 9 superfamily protein member 2 precursor
Length = 662
Score = 247 bits (631), Expect = 2e-65
Identities = 115/171 (67%), Positives = 131/171 (76%)
Frame = +2
Query: 2 FKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVY 181
FKK I PVRTNQIPRQIP Q YT+ +P I+MGG+LPFGCIFIQLFFILNSIWS +Y
Sbjct: 492 FKKNAIEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFIQLFFILNSIWSHQMY 551
Query: 182 YMFGXXXXXXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFH 361
YMFG TCSE TILLCYFHLCAEDY W WRSFLTSG TA+Y IY+I++F
Sbjct: 552 YMFGFLFLVFIILVITCSEATILLCYFHLCAEDYHWQWRSFLTSGFTAVYFLIYAIHYFF 611
Query: 362 AKLDIKGSTSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 514
+KL I G+ ST LYFGYT I++ + FL TGT+GF + FWFV KIYSVVKVD
Sbjct: 612 SKLQITGTASTILYFGYTMIMVLIFFLFTGTIGFFACFWFVTKIYSVVKVD 662
>sp|Q66HG5|TM9S2_RAT Transmembrane 9 superfamily protein member 2 precursor
Length = 663
Score = 247 bits (630), Expect = 2e-65
Identities = 114/171 (66%), Positives = 131/171 (76%)
Frame = +2
Query: 2 FKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVY 181
FKK I PVRTNQIPRQIP Q YT+ +P I+MGG+LPFGCIFIQLFFILNSIWS +Y
Sbjct: 493 FKKNAIEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFIQLFFILNSIWSHQMY 552
Query: 182 YMFGXXXXXXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFH 361
YMFG TCSE TILLCYFHLCAEDY W WRSFLTSG TA+Y +Y+I++F
Sbjct: 553 YMFGFLFLVFIILVITCSEATILLCYFHLCAEDYHWQWRSFLTSGFTAVYFLVYAIHYFF 612
Query: 362 AKLDIKGSTSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 514
+KL I G+ ST LYFGYT I++ + FL TGT+GF + FWFV KIYSVVKVD
Sbjct: 613 SKLQITGTASTILYFGYTMIMVLIFFLFTGTIGFFACFWFVTKIYSVVKVD 663
>sp|Q99805|TM9S2_HUMAN Transmembrane 9 superfamily protein member 2 precursor (p76)
Length = 663
Score = 247 bits (630), Expect = 2e-65
Identities = 114/171 (66%), Positives = 131/171 (76%)
Frame = +2
Query: 2 FKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVY 181
FKK I PVRTNQIPRQIP Q YT+ +P I+MGG+LPFGCIFIQLFFILNSIWS +Y
Sbjct: 493 FKKNAIEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFIQLFFILNSIWSHQMY 552
Query: 182 YMFGXXXXXXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFH 361
YMFG TCSE TILLCYFHLCAEDY W WRSFLTSG TA+Y IY++++F
Sbjct: 553 YMFGFLFLVFIILVITCSEATILLCYFHLCAEDYHWQWRSFLTSGFTAVYFLIYAVHYFF 612
Query: 362 AKLDIKGSTSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 514
+KL I G+ ST LYFGYT I++ + FL TGT+GF + FWFV KIYSVVKVD
Sbjct: 613 SKLQITGTASTILYFGYTMIMVLIFFLFTGTIGFFACFWFVTKIYSVVKVD 663
>sp|Q5R8Y6|TM9S2_PONPY Transmembrane 9 superfamily protein member 2 precursor
Length = 663
Score = 247 bits (630), Expect = 2e-65
Identities = 114/171 (66%), Positives = 131/171 (76%)
Frame = +2
Query: 2 FKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVY 181
FKK I PVRTNQIPRQIP Q YT+ +P I+MGG+LPFGCIFIQLFFILNSIWS +Y
Sbjct: 493 FKKNAIEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFIQLFFILNSIWSHQMY 552
Query: 182 YMFGXXXXXXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFH 361
YMFG TCSE TILLCYFHLCAEDY W WRSFLTSG TA+Y IY++++F
Sbjct: 553 YMFGFLFLVFIILVITCSEATILLCYFHLCAEDYHWQWRSFLTSGFTAVYFLIYAVHYFF 612
Query: 362 AKLDIKGSTSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 514
+KL I G+ ST LYFGYT I++ + FL TGT+GF + FWFV KIYSVVKVD
Sbjct: 613 SKLQITGTASTILYFGYTMIMVLIFFLFTGTIGFFACFWFVTKIYSVVKVD 663
>sp|Q92544|TM9S4_HUMAN Transmembrane 9 superfamily protein member 4
Length = 625
Score = 199 bits (507), Expect = 4e-51
Identities = 89/171 (52%), Positives = 120/171 (70%)
Frame = +2
Query: 2 FKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVY 181
F+KQP PVRTNQIPRQIP Q Y ILM G+LPFG +FI+LFFI ++IW Y
Sbjct: 455 FRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFY 514
Query: 182 YMFGXXXXXXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFH 361
Y+FG +CS+ +I++ YF LCAEDYRWWWR+FL SG +A Y+ +Y+I++F
Sbjct: 515 YLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFV 574
Query: 362 AKLDIKGSTSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 514
KLDI + LYFGYTA+++ +L+TGT+GF +++ FVRKIY+ VK+D
Sbjct: 575 NKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID 625
>sp|P32802|EMP70_YEAST Endosomal P24A protein precursor (70 kDa endomembrane protein)
(Pheromone alpha-factor transporter) (Acidic 24 kDa late
endocytic intermediate component)
Length = 667
Score = 156 bits (394), Expect = 5e-38
Identities = 77/164 (46%), Positives = 106/164 (64%), Gaps = 1/164 (0%)
Frame = +2
Query: 26 PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFGXXXX 205
P +TNQI RQIP+Q Y ++IP+ L+ G+ PFG I ++L+FI S+W ++YMFG
Sbjct: 506 PTKTNQIARQIPFQPWYLKTIPATLIAGIFPFGSIAVELYFIYTSLWFNKIFYMFGFLFF 565
Query: 206 XXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGC-TALYLFIYSIYFFHAKLDIKG 382
T S TIL+ Y LC E+++W WR F+ G ALY+FI+SI F K + G
Sbjct: 566 SFLLLTLTSSLVTILITYHSLCLENWKWQWRGFIIGGAGCALYVFIHSILF--TKFKLGG 623
Query: 383 STSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 514
T+ LY GY+++I L LVTG++GF+SS FVRKIYS +KVD
Sbjct: 624 FTTIVLYVGYSSVISLLCCLVTGSIGFISSMLFVRKIYSSIKVD 667
>sp|Q9ET30|TM9S3_MOUSE Transmembrane 9 superfamily protein member 3 precursor
Length = 587
Score = 136 bits (342), Expect = 5e-32
Identities = 63/163 (38%), Positives = 95/163 (58%)
Frame = +2
Query: 26 PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFGXXXX 205
P R N +PR IP + + + +GG+LPFG IFI+++FI S W+ +YY++G
Sbjct: 425 PCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMML 484
Query: 206 XXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFHAKLDIKGS 385
TI+ YF L AEDYRW W SFL++ TA+Y+++YS Y++ K + G
Sbjct: 485 VLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGL 544
Query: 386 TSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 514
T YFGY A+ ++ G +G++ + FVRKIY+ VK+D
Sbjct: 545 FQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID 587
>sp|Q9HD45|TM9S3_HUMAN Transmembrane 9 superfamily protein member 3 precursor (SM-11044
binding protein) (EP70-P-iso)
Length = 589
Score = 136 bits (342), Expect = 5e-32
Identities = 63/163 (38%), Positives = 95/163 (58%)
Frame = +2
Query: 26 PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFGXXXX 205
P R N +PR IP + + + +GG+LPFG IFI+++FI S W+ +YY++G
Sbjct: 427 PCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMML 486
Query: 206 XXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFHAKLDIKGS 385
TI+ YF L AEDYRW W SFL++ TA+Y+++YS Y++ K + G
Sbjct: 487 VLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGL 546
Query: 386 TSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 514
T YFGY A+ ++ G +G++ + FVRKIY+ VK+D
Sbjct: 547 FQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID 589
>sp|O15321|TM9S1_HUMAN Transmembrane 9 superfamily protein member 1 precursor (hMP70)
Length = 606
Score = 132 bits (333), Expect = 5e-31
Identities = 60/167 (35%), Positives = 97/167 (58%)
Frame = +2
Query: 14 PISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFG 193
P P RT I R+IP Q Y ++ + +GG LPF I ++L++I ++W Y ++G
Sbjct: 440 PFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISVELYYIFATVWGREQYTLYG 499
Query: 194 XXXXXXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFHAKLD 373
+ +I L YF L EDYRWWWRS L+ G T L++F+YS++++ + +
Sbjct: 500 ILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSN 559
Query: 374 IKGSTSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 514
+ G+ T +FGY+ + ++ FL+ GT+ F SS F+R IY +K+D
Sbjct: 560 MSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD 606
>sp|Q9DBU0|TM9S1_MOUSE Transmembrane 9 superfamily protein member 1 precursor
Length = 606
Score = 132 bits (333), Expect = 5e-31
Identities = 60/167 (35%), Positives = 97/167 (58%)
Frame = +2
Query: 14 PISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFG 193
P P RT I R+IP Q Y ++ + +GG LPF I ++L++I ++W Y ++G
Sbjct: 440 PFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISVELYYIFATVWGREQYTLYG 499
Query: 194 XXXXXXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFHAKLD 373
+ +I L YF L EDYRWWWRS L+ G T L++F+YS++++ + +
Sbjct: 500 ILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSN 559
Query: 374 IKGSTSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 514
+ G+ T +FGY+ + ++ FL+ GT+ F SS F+R IY +K+D
Sbjct: 560 MSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD 606
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,043,942
Number of Sequences: 369166
Number of extensions: 1472059
Number of successful extensions: 3616
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3493
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3608
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 4926080070
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)