Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_M21
(632 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q26534|CATL_SCHMA Cathepsin L precursor (SMCL1) 248 7e-66
sp|Q9R013|CATF_MOUSE Cathepsin F precursor 236 3e-62
sp|Q9UBX1|CATF_HUMAN Cathepsin F precursor (CATSF) 231 9e-61
sp|Q9VN93|CPR1_DROME Putative cysteine proteinase CG12163 p... 230 2e-60
sp|P04988|CYSP1_DICDI Cysteine proteinase 1 precursor 188 1e-47
sp|P25804|CYSP_PEA Cysteine proteinase 15A precursor (Turgo... 180 3e-45
sp|P43296|RD19A_ARATH Cysteine proteinase RD19a precursor (... 176 3e-44
sp|Q10716|CYSP1_MAIZE Cysteine proteinase 1 precursor 176 6e-44
sp|P43295|A494_ARATH Probable cysteine proteinase A494 prec... 175 1e-43
sp|P14658|CYSP_TRYBB Cysteine proteinase precursor 172 5e-43
>sp|Q26534|CATL_SCHMA Cathepsin L precursor (SMCL1)
Length = 319
Score = 248 bits (634), Expect = 7e-66
Identities = 112/192 (58%), Positives = 143/192 (74%)
Frame = +1
Query: 1 SCWAFSTTGNIEGQWFIRTKRLVSLSEQQLVDCDTVDEGCNGGLPSQAYKVIQQMGGLET 180
SCWAFSTTGN+E QWF +T +L+SLSEQQLVDCD +D+GCNGGLPS AY+ I +MGGL
Sbjct: 128 SCWAFSTTGNVESQWFRKTGKLLSLSEQQLVDCDGLDDGCNGGLPSNAYESIIKMGGLML 187
Query: 181 ESDYPYKADRKTCMLDKSKIAVYINGSESIDSSETTMAAWCSINGPISIGINAFAMQFYR 360
E +YPY A + C L +AVYIN S ++ ET +AAW N IS+G+NA +QFY+
Sbjct: 188 EDNYPYDAKNEKCHLKTDGVAVYINSSVNLTQDETELAAWLYHNSTISVGMNALLLQFYQ 247
Query: 361 GGISHPFKIFCNPDHLDHGVLIVGFNTTSSGEPFWIVKNSWGPGWGEDGYYRVFRGTGVC 540
GISHP+ IFC+ LDH VL+VG+ + EPFWIVKNSWG WGE+GY+R++RG G C
Sbjct: 248 HGISHPWWIFCSKYLLDHAVLLVGYGVSEKNEPFWIVKNSWGVEWGENGYFRMYRGDGSC 307
Query: 541 GLNKMPTSAIIH 576
G+N + TSA+I+
Sbjct: 308 GINTVATSAMIY 319
>sp|Q9R013|CATF_MOUSE Cathepsin F precursor
Length = 462
Score = 236 bits (603), Expect = 3e-62
Identities = 104/192 (54%), Positives = 137/192 (71%)
Frame = +1
Query: 1 SCWAFSTTGNIEGQWFIRTKRLVSLSEQQLVDCDTVDEGCNGGLPSQAYKVIQQMGGLET 180
SCWAFS TGN+EGQWF+ L+SLSEQ+L+DCD VD+ C GGLPS AY I+ +GGLET
Sbjct: 272 SCWAFSVTGNVEGQWFLNRGTLLSLSEQELLDCDKVDKACLGGLPSNAYAAIKNLGGLET 331
Query: 181 ESDYPYKADRKTCMLDKSKIAVYINGSESIDSSETTMAAWCSINGPISIGINAFAMQFYR 360
E DY Y+ +TC VYIN S + +E +AAW + GPIS+ INAF MQFYR
Sbjct: 332 EDDYGYQGHVQTCNFSAQMAKVYINDSVELSRNENKIAAWLAQKGPISVAINAFGMQFYR 391
Query: 361 GGISHPFKIFCNPDHLDHGVLIVGFNTTSSGEPFWIVKNSWGPGWGEDGYYRVFRGTGVC 540
GI+HPF+ C+P +DH VL+VG+ S+ P+W +KNSWG WGE+GYY ++RG+G C
Sbjct: 392 HGIAHPFRPLCSPWFIDHAVLLVGYGNRSN-IPYWAIKNSWGSDWGEEGYYYLYRGSGAC 450
Query: 541 GLNKMPTSAIIH 576
G+N M +SA+++
Sbjct: 451 GVNTMASSAVVN 462
>sp|Q9UBX1|CATF_HUMAN Cathepsin F precursor (CATSF)
Length = 484
Score = 231 bits (590), Expect = 9e-61
Identities = 103/191 (53%), Positives = 132/191 (69%)
Frame = +1
Query: 1 SCWAFSTTGNIEGQWFIRTKRLVSLSEQQLVDCDTVDEGCNGGLPSQAYKVIQQMGGLET 180
SCWAFS TGN+EGQWF+ L+SLSEQ+L+DCD +D+ C GGLPS AY I+ +GGLET
Sbjct: 294 SCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLET 353
Query: 181 ESDYPYKADRKTCMLDKSKIAVYINGSESIDSSETTMAAWCSINGPISIGINAFAMQFYR 360
E DY Y+ ++C K VYIN S + +E +AAW + GPIS+ INAF MQFYR
Sbjct: 354 EDDYSYQGHMQSCNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYR 413
Query: 361 GGISHPFKIFCNPDHLDHGVLIVGFNTTSSGEPFWIVKNSWGPGWGEDGYYRVFRGTGVC 540
GIS P + C+P +DH VL+VG+ S PFW +KNSWG WGE GYY + RG+G C
Sbjct: 414 HGISRPLRPLCSPWLIDHAVLLVGYGNRSD-VPFWAIKNSWGTDWGEKGYYYLHRGSGAC 472
Query: 541 GLNKMPTSAII 573
G+N M +SA++
Sbjct: 473 GVNTMASSAVV 483
>sp|Q9VN93|CPR1_DROME Putative cysteine proteinase CG12163 precursor
Length = 614
Score = 230 bits (587), Expect = 2e-60
Identities = 106/197 (53%), Positives = 136/197 (69%), Gaps = 6/197 (3%)
Frame = +1
Query: 1 SCWAFSTTGNIEGQWFIRTKRLVSLSEQQLVDCDTVDEGCNGGLPSQAYKVIQQMGGLET 180
SCWAFS TGNIEG + ++T L SEQ+L+DCDT D CNGGL AYK I+ +GGLE
Sbjct: 417 SCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKDIGGLEY 476
Query: 181 ESDYPYKADRKTCMLDKSKIAVYINGSESI-DSSETTMAAWCSINGPISIGINAFAMQFY 357
E++YPYKA + C +++ V + G + +ET M W NGPISIGINA AMQFY
Sbjct: 477 EAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQFY 536
Query: 358 RGGISHPFKIFCNPDHLDHGVLIVGFNTTSSGE-----PFWIVKNSWGPGWGEDGYYRVF 522
RGG+SHP+K C+ +LDHGVL+VG+ + P+WIVKNSWGP WGE GYYRV+
Sbjct: 537 RGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVY 596
Query: 523 RGTGVCGLNKMPTSAII 573
RG CG+++M TSA++
Sbjct: 597 RGDNTCGVSEMATSAVL 613
>sp|P04988|CYSP1_DICDI Cysteine proteinase 1 precursor
Length = 343
Score = 188 bits (477), Expect = 1e-47
Identities = 97/206 (47%), Positives = 126/206 (61%), Gaps = 15/206 (7%)
Frame = +1
Query: 1 SCWAFSTTGNIEGQWFIRTKRLVSLSEQQLVDCD----------TVDEGCNGGLPSQAYK 150
SCW+FSTTGN+EGQ FI +LVSLSEQ LVDCD DEGCNGGL AY
Sbjct: 141 SCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYN 200
Query: 151 VIQQMGGLETESDYPYKADRKT-CMLDKSKIAVYINGSESIDSSETTMAAWCSINGPISI 327
I + GG++TES YPY A+ T C + + I I+ I +ET MA + GP++I
Sbjct: 201 YIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAI 260
Query: 328 GINAFAMQFYRGGISHPFKIFCNPDHLDHGVLIVGFNTTSS----GEPFWIVKNSWGPGW 495
+A QFY GG+ F I CNP+ LDHG+LIVG++ ++ P+WIVKNSWG W
Sbjct: 261 AADAVEWQFYIGGV---FDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADW 317
Query: 496 GEDGYYRVFRGTGVCGLNKMPTSAII 573
GE GY + RG CG++ +++II
Sbjct: 318 GEQGYIYLRRGKNTCGVSNFVSTSII 343
>sp|P25804|CYSP_PEA Cysteine proteinase 15A precursor (Turgor-responsive protein 15A)
Length = 363
Score = 180 bits (456), Expect = 3e-45
Identities = 90/200 (45%), Positives = 120/200 (60%), Gaps = 15/200 (7%)
Frame = +1
Query: 1 SCWAFSTTGNIEGQWFIRTKRLVSLSEQQLVDCDTV---------DEGCNGGLPSQAYKV 153
SCWAFSTTG +EG ++ T +LVSLSEQQLVDCD V D GCNGGL + A++
Sbjct: 155 SCWAFSTTGALEGAHYLATGKLVSLSEQQLVDCDHVCDPEQAGSCDSGCNGGLMNNAFEY 214
Query: 154 IQQMGGLETESDYPYKADRKTCMLDKSKIAVYINGSESIDSSETTMAAWCSINGPISIGI 333
+ + GG+ E DY Y +C DKSK+ ++ + E +AA NGP+++ I
Sbjct: 215 LLESGGVVQEKDYAYTGRDGSCKFDKSKVVASVSNFSVVTLDEDQIAANLVKNGPLAVAI 274
Query: 334 NAFAMQFYRGGISHPFKIFCNPDHLDHGVLIVGFNTTS------SGEPFWIVKNSWGPGW 495
NA MQ Y G+S P+ C LDHGVL+VGF + +P+WI+KNSWG W
Sbjct: 275 NAAWMQTYMSGVSCPY--VCAKSRLDHGVLLVGFGKGAYAPIRLKEKPYWIIKNSWGQNW 332
Query: 496 GEDGYYRVFRGTGVCGLNKM 555
GE GYY++ RG VCG++ M
Sbjct: 333 GEQGYYKICRGRNVCGVDSM 352
>sp|P43296|RD19A_ARATH Cysteine proteinase RD19a precursor (RD19)
Length = 368
Score = 176 bits (447), Expect = 3e-44
Identities = 92/201 (45%), Positives = 123/201 (61%), Gaps = 16/201 (7%)
Frame = +1
Query: 1 SCWAFSTTGNIEGQWFIRTKRLVSLSEQQLVDCD---------TVDEGCNGGLPSQAYKV 153
SCW+FS TG +EG F+ T +LVSLSEQQLVDCD + D GCNGGL + A++
Sbjct: 158 SCWSFSATGALEGANFLATGKLVSLSEQQLVDCDHECDPEEADSCDSGCNGGLMNSAFEY 217
Query: 154 IQQMGGLETESDYPYKA-DRKTCMLDKSKIAVYINGSESIDSSETTMAAWCSINGPISIG 330
+ GGL E DYPY D KTC LDKSKI ++ I E +AA NGP+++
Sbjct: 218 TLKTGGLMKEEDYPYTGKDGKTCKLDKSKIVASVSNFSVISIDEEQIAANLVKNGPLAVA 277
Query: 331 INAFAMQFYRGGISHPFKIFCNPDHLDHGVLIVGFNTTSSG------EPFWIVKNSWGPG 492
INA MQ Y GG+S P+ C L+HGVL+VG+ +P+WI+KNSWG
Sbjct: 278 INAGYMQTYIGGVSCPY--ICTR-RLNHGVLLVGYGAAGYAPARFKEKPYWIIKNSWGET 334
Query: 493 WGEDGYYRVFRGTGVCGLNKM 555
WGE+G+Y++ +G +CG++ M
Sbjct: 335 WGENGFYKICKGRNICGVDSM 355
>sp|Q10716|CYSP1_MAIZE Cysteine proteinase 1 precursor
Length = 371
Score = 176 bits (445), Expect = 6e-44
Identities = 91/211 (43%), Positives = 126/211 (59%), Gaps = 19/211 (9%)
Frame = +1
Query: 1 SCWAFSTTGNIEGQWFIRTKRLVSLSEQQLVDCD---------TVDEGCNGGLPSQAYKV 153
SCW+FS +G +EG ++ T +L LSEQQ VDCD + D GCNGGL + A+
Sbjct: 160 SCWSFSASGALEGAHYLATGKLEVLSEQQFVDCDHECDSSEPDSCDSGCNGGLMTTAFSY 219
Query: 154 IQQMGGLETESDYPYKADRKTCMLDKSKIAVYINGSESIDSSETTMAAWCSINGPISIGI 333
+Q+ GGLE+E DYPY C DKSKI + + E ++A +GP++IGI
Sbjct: 220 LQKAGGLESEKDYPYTGSDGKCKFDKSKIVASVQNFSVVSVDEAQISANLIKHGPLAIGI 279
Query: 334 NAFAMQFYRGGISHPFKIFCNPDHLDHGVLIVGFNTTS------SGEPFWIVKNSWGPGW 495
NA MQ Y GG+S P+ C HLDHGVL+VG+ + +P+WI+KNSWG W
Sbjct: 280 NAAYMQTYIGGVSCPY--ICG-RHLDHGVLLVGYGASGFAPIRLKDKPYWIIKNSWGENW 336
Query: 496 GEDGYYRVFRGTGV---CGLNKM-PTSAIIH 576
GE+GYY++ RG+ V CG++ M T + +H
Sbjct: 337 GENGYYKICRGSNVRNKCGVDSMVSTVSAVH 367
>sp|P43295|A494_ARATH Probable cysteine proteinase A494 precursor
Length = 361
Score = 175 bits (443), Expect = 1e-43
Identities = 88/201 (43%), Positives = 126/201 (62%), Gaps = 16/201 (7%)
Frame = +1
Query: 1 SCWAFSTTGNIEGQWFIRTKRLVSLSEQQLVDCD---------TVDEGCNGGLPSQAYKV 153
SCW+FSTTG +EG F+ T +LVSLSEQQLVDCD + D GCNGGL + A++
Sbjct: 155 SCWSFSTTGALEGAHFLATGKLVSLSEQQLVDCDHECDPEEEGSCDSGCNGGLMNSAFEY 214
Query: 154 IQQMGGLETESDYPYK-ADRKTCMLDKSKIAVYINGSESIDSSETTMAAWCSINGPISIG 330
+ GGL E DYPY D +C LD+SKI ++ + +E +AA NGP+++
Sbjct: 215 TLKTGGLMREKDYPYTGTDGGSCKLDRSKIVASVSNFSVVSINEDQIAANLIKNGPLAVA 274
Query: 331 INAFAMQFYRGGISHPFKIFCNPDHLDHGVLIVGFNTTSSGE------PFWIVKNSWGPG 492
INA MQ Y GG+S P+ C+ L+HGVL+VG+ + + P+WI+KNSWG
Sbjct: 275 INAAYMQTYIGGVSCPY--ICS-RRLNHGVLLVGYGSAGFSQARLKEKPYWIIKNSWGES 331
Query: 493 WGEDGYYRVFRGTGVCGLNKM 555
WGE+G+Y++ +G +CG++ +
Sbjct: 332 WGENGFYKICKGRNICGVDSL 352
>sp|P14658|CYSP_TRYBB Cysteine proteinase precursor
Length = 450
Score = 172 bits (437), Expect = 5e-43
Identities = 87/196 (44%), Positives = 120/196 (61%), Gaps = 5/196 (2%)
Frame = +1
Query: 1 SCWAFSTTGNIEGQWFIRTKRLVSLSEQQLVDCDTVDEGCNGGLPSQAYK-VIQQMGG-L 174
SCWAFST GNIEGQW + LVSLSEQ LV CDT+D GCNGGL A+ ++ GG +
Sbjct: 149 SCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCDTIDSGCNGGLMDNAFNWIVNSNGGNV 208
Query: 175 ETESDYPY---KADRKTCMLDKSKIAVYINGSESIDSSETTMAAWCSINGPISIGINAFA 345
TE+ YPY ++ C ++ +I I + E +AA+ + NGP++I ++A +
Sbjct: 209 FTEASYPYVSGNGEQPQCQMNGHEIGAAITDHVDLPQDEDAIAAYLAENGPLAIAVDAES 268
Query: 346 MQFYRGGISHPFKIFCNPDHLDHGVLIVGFNTTSSGEPFWIVKNSWGPGWGEDGYYRVFR 525
Y GGI C LDHGVL+VG+N +S P+WI+KNSW WGEDGY R+ +
Sbjct: 269 FMDYNGGI----LTSCTSKQLDHGVLLVGYN-DNSNPPYWIIKNSWSNMWGEDGYIRIEK 323
Query: 526 GTGVCGLNKMPTSAII 573
GT C +N+ +SA++
Sbjct: 324 GTNQCLMNQAVSSAVV 339
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,070,050
Number of Sequences: 369166
Number of extensions: 1441279
Number of successful extensions: 3595
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3186
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3255
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5072399280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)