Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_M15
(767 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53597|SUCA_HUMAN Succinyl-CoA ligase [GDP-forming] alph... 268 1e-71
sp|P13086|SUCA_RAT Succinyl-CoA ligase [GDP-forming] alpha-... 263 3e-70
sp|Q9WUM5|SUCA_MOUSE Succinyl-CoA ligase [GDP-forming] alph... 261 2e-69
sp|P53596|SUCA_CAEEL Probable succinyl-CoA ligase [GDP-form... 260 3e-69
sp|Q94522|SUCA_DROME Succinyl-CoA ligase [GDP-forming] alph... 250 3e-66
sp|P36967|SUCA_DICDI Succinyl-CoA ligase [GDP-forming] alph... 233 3e-61
sp|Q8LAD2|SUCA2_ARATH Succinyl-CoA ligase [GDP-forming] alp... 228 2e-59
sp|P68209|SUCA1_ARATH Succinyl-CoA ligase [GDP-forming] alp... 227 3e-59
sp|O13750|SUCA_SCHPO Probable succinyl-CoA ligase [GDP-form... 217 2e-56
sp|O19069|SUCA_PIG Succinyl-CoA ligase [GDP-forming] alpha-... 214 3e-55
>sp|P53597|SUCA_HUMAN Succinyl-CoA ligase [GDP-forming] alpha-chain, mitochondrial
precursor (Succinyl-CoA synthetase, alpha chain)
(SCS-alpha)
Length = 333
Score = 268 bits (685), Expect = 1e-71
Identities = 129/205 (62%), Positives = 155/205 (75%)
Frame = +3
Query: 3 PLVVCITEGIPQQDMVRVKNRLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIG 182
PLVVCITEGIPQQDMVRVK++L+ QEKTRLIGPNCPG+I P +CKIGIMP HIHK G+IG
Sbjct: 125 PLVVCITEGIPQQDMVRVKHKLLRQEKTRLIGPNCPGVINPGECKIGIMPGHIHKKGRIG 184
Query: 183 IVSRSGTLTYEAVHQTSQVGLGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXX 362
IVSRSGTLTYEAVHQT+QVGLGQSL +GIGGDPFNGT+F+DCLE+F+ D T+
Sbjct: 185 IVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDFIDCLEIFLNDSATEGIILIGE 244
Query: 363 XXXXXXXXXXMYLEKHNAGPNRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDA 542
+L++HN+GPN K VVSFIAGLTAPPGRRM +EKI A
Sbjct: 245 IGGNAEENAAEFLKQHNSGPNSKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKISA 304
Query: 543 LKHAGVIVTLSPAQMGASMIEALHK 617
L+ AGV+V++SPAQ+G ++ + K
Sbjct: 305 LQSAGVVVSMSPAQLGTTIYKEFEK 329
>sp|P13086|SUCA_RAT Succinyl-CoA ligase [GDP-forming] alpha-chain, mitochondrial
precursor (Succinyl-CoA synthetase, alpha chain)
(SCS-alpha)
Length = 333
Score = 263 bits (673), Expect = 3e-70
Identities = 130/205 (63%), Positives = 152/205 (74%)
Frame = +3
Query: 3 PLVVCITEGIPQQDMVRVKNRLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIG 182
PLVVCITEGIPQQDM+RVK++L Q KTRLIGPNCPGII P +CKIGIMP HIHK G+IG
Sbjct: 125 PLVVCITEGIPQQDMLRVKHKLTRQGKTRLIGPNCPGIINPGECKIGIMPGHIHKKGRIG 184
Query: 183 IVSRSGTLTYEAVHQTSQVGLGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXX 362
IVSRSGTLTYEAVHQT+QVGLGQSL IGIGGDPFNGTNF+DCL+VF++D T+
Sbjct: 185 IVSRSGTLTYEAVHQTTQVGLGQSLCIGIGGDPFNGTNFIDCLDVFLKDPATEGIVLIGE 244
Query: 363 XXXXXXXXXXMYLEKHNAGPNRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDA 542
+L++HN+GP K VVSFIAG+TAPPGRRM +EKI A
Sbjct: 245 IGGHAEENAAEFLKEHNSGPKAKPVVSFIAGITAPPGRRMGHAGAIIAGGKGGAKEKISA 304
Query: 543 LKHAGVIVTLSPAQMGASMIEALHK 617
L+ AGVIV++SPAQ+G M + K
Sbjct: 305 LQSAGVIVSMSPAQLGTCMYKEFEK 329
>sp|Q9WUM5|SUCA_MOUSE Succinyl-CoA ligase [GDP-forming] alpha-chain, mitochondrial
precursor (Succinyl-CoA synthetase, alpha chain)
(SCS-alpha)
Length = 333
Score = 261 bits (666), Expect = 2e-69
Identities = 128/205 (62%), Positives = 151/205 (73%)
Frame = +3
Query: 3 PLVVCITEGIPQQDMVRVKNRLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIG 182
PLVVCITEGIPQQDMVRVK+RL Q TRLIGPNCPG+I P +CKIGIMP HIHK G+IG
Sbjct: 125 PLVVCITEGIPQQDMVRVKHRLTRQGTTRLIGPNCPGVINPGECKIGIMPGHIHKKGRIG 184
Query: 183 IVSRSGTLTYEAVHQTSQVGLGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXX 362
IVSRSGTLTYEAVHQT+QVGLGQSL IGIGGDPFNGT+F+DCLEVF+ D T+
Sbjct: 185 IVSRSGTLTYEAVHQTTQVGLGQSLCIGIGGDPFNGTDFIDCLEVFLNDPATEGIILIGE 244
Query: 363 XXXXXXXXXXMYLEKHNAGPNRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDA 542
+L++HN+GP K VVSFIAG+TAPPGRRM +EKI A
Sbjct: 245 IGGHAEENAAAFLKEHNSGPKAKPVVSFIAGITAPPGRRMGHAGAIIAGGKGGAKEKISA 304
Query: 543 LKHAGVIVTLSPAQMGASMIEALHK 617
L+ AGV+V++SPAQ+G ++ + K
Sbjct: 305 LQSAGVVVSMSPAQLGTTIYKEFEK 329
>sp|P53596|SUCA_CAEEL Probable succinyl-CoA ligase [GDP-forming] alpha-chain,
mitochondrial precursor (Succinyl-CoA synthetase, alpha
chain) (SCS-alpha)
Length = 322
Score = 260 bits (664), Expect = 3e-69
Identities = 129/202 (63%), Positives = 148/202 (73%)
Frame = +3
Query: 3 PLVVCITEGIPQQDMVRVKNRLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIG 182
PLVVCITEGIPQ DMVRVK+RL+ Q KTRL+GPNCPGII +QCKIGIMP HIHK G IG
Sbjct: 116 PLVVCITEGIPQHDMVRVKSRLLKQNKTRLVGPNCPGIISADQCKIGIMPGHIHKRGCIG 175
Query: 183 IVSRSGTLTYEAVHQTSQVGLGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXX 362
IVSRSGTLTYEAVHQT+QVG GQ+L +GIGGDPFNGTNF+DCL VF+ D TK
Sbjct: 176 IVSRSGTLTYEAVHQTTQVGFGQTLCVGIGGDPFNGTNFIDCLNVFLEDPETKGIILIGE 235
Query: 363 XXXXXXXXXXMYLEKHNAGPNRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDA 542
YL++HN+G NRK VVSFIAG+TAPPGRRM +KI+A
Sbjct: 236 IGGSAEEEAAAYLKEHNSGANRKPVVSFIAGVTAPPGRRMGHAGAIISGGKGTAADKINA 295
Query: 543 LKHAGVIVTLSPAQMGASMIEA 608
L+ AGV+VT SPA++G SM A
Sbjct: 296 LREAGVVVTDSPAKLGTSMATA 317
>sp|Q94522|SUCA_DROME Succinyl-CoA ligase [GDP-forming] alpha-chain, mitochondrial
precursor (Succinyl-CoA synthetase, alpha chain)
(SCS-alpha)
Length = 328
Score = 250 bits (638), Expect = 3e-66
Identities = 122/206 (59%), Positives = 150/206 (72%)
Frame = +3
Query: 3 PLVVCITEGIPQQDMVRVKNRLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIG 182
PL+VCITEG+PQ DMV+VK+ LI+Q K+RL+GPNCPGII P QCKIGIMP HIHK GKIG
Sbjct: 120 PLIVCITEGVPQHDMVKVKHALISQSKSRLVGPNCPGIIAPEQCKIGIMPGHIHKRGKIG 179
Query: 183 IVSRSGTLTYEAVHQTSQVGLGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXX 362
+VSRSGTLTYEAVHQT++VGLGQ+L +GIGGDPFNGT+F+DCLEVF++D TK
Sbjct: 180 VVSRSGTLTYEAVHQTTEVGLGQTLCVGIGGDPFNGTDFIDCLEVFLKDPETKGIILIGE 239
Query: 363 XXXXXXXXXXMYLEKHNAGPNRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDA 542
YL ++N+G K VVSFIAG++APPGRRM +KI A
Sbjct: 240 IGGVAEEKAADYLTEYNSGIKAKPVVSFIAGVSAPPGRRMGHAGAIISGGKGGANDKIAA 299
Query: 543 LKHAGVIVTLSPAQMGASMIEALHKL 620
L+ AGVIVT SPA+MG + + + +L
Sbjct: 300 LEKAGVIVTRSPAKMGHELFKEMKRL 325
>sp|P36967|SUCA_DICDI Succinyl-CoA ligase [GDP-forming] alpha-chain, mitochondrial
precursor (Succinyl-CoA synthetase, alpha chain)
(SCS-alpha)
Length = 310
Score = 233 bits (595), Expect = 3e-61
Identities = 122/199 (61%), Positives = 139/199 (69%)
Frame = +3
Query: 6 LVVCITEGIPQQDMVRVKNRLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIGI 185
LVVCITEGIPQQDMV+VK L Q KTRLIGPNCPGIIKP +CKIGIMP HIHKPGKIGI
Sbjct: 111 LVVCITEGIPQQDMVKVKYLLNKQNKTRLIGPNCPGIIKPGECKIGIMPGHIHKPGKIGI 170
Query: 186 VSRSGTLTYEAVHQTSQVGLGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXXX 365
VSRSGTLTYEAV QT+ VGLGQS IGIGGDPFNGTNF+DCL++F +D T+
Sbjct: 171 VSRSGTLTYEAVAQTTAVGLGQSTCIGIGGDPFNGTNFIDCLKMFTQDPQTEGIILIGEI 230
Query: 366 XXXXXXXXXMYLEKHNAGPNRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDAL 545
+L + P K VVSFIAGL+APPGRRM KI+AL
Sbjct: 231 GGEAEEEAAQWLIDN---PTDKPVVSFIAGLSAPPGRRMGHAGAIISGGKGDANSKIEAL 287
Query: 546 KHAGVIVTLSPAQMGASMI 602
K AGV VT SPA++G +++
Sbjct: 288 KAAGVTVTFSPAKLGETIL 306
>sp|Q8LAD2|SUCA2_ARATH Succinyl-CoA ligase [GDP-forming] alpha-chain 2, mitochondrial
precursor (Succinyl-CoA synthetase 2, alpha chain)
(SCS2-alpha)
Length = 341
Score = 228 bits (580), Expect = 2e-59
Identities = 120/200 (60%), Positives = 138/200 (69%)
Frame = +3
Query: 6 LVVCITEGIPQQDMVRVKNRLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIGI 185
L+VCITEGIPQ DMVRVK L +Q KTRLIGPNCPGIIKP +CKIGIMP +IHKPGKIGI
Sbjct: 136 LIVCITEGIPQHDMVRVKAALNSQSKTRLIGPNCPGIIKPGECKIGIMPGYIHKPGKIGI 195
Query: 186 VSRSGTLTYEAVHQTSQVGLGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXXX 365
VSRSGTLTYEAV QT+ VGLGQS +GIGGDPFNGTNFVDCLE F D T+
Sbjct: 196 VSRSGTLTYEAVFQTTAVGLGQSTCVGIGGDPFNGTNFVDCLEKFFVDPQTEGIVLIGEI 255
Query: 366 XXXXXXXXXMYLEKHNAGPNRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDAL 545
++++ K VV+FIAGLTAPPGRRM Q+KI +L
Sbjct: 256 GGTAEEDAAALIKENGTD---KPVVAFIAGLTAPPGRRMGHAGAIVSGGKGTAQDKIKSL 312
Query: 546 KHAGVIVTLSPAQMGASMIE 605
+ AGV V SPA++GA+M E
Sbjct: 313 RDAGVKVVESPAKIGAAMFE 332
>sp|P68209|SUCA1_ARATH Succinyl-CoA ligase [GDP-forming] alpha-chain 1, mitochondrial
precursor (Succinyl-CoA synthetase 1, alpha chain)
(SCS1-alpha)
Length = 347
Score = 227 bits (578), Expect = 3e-59
Identities = 120/200 (60%), Positives = 137/200 (68%)
Frame = +3
Query: 6 LVVCITEGIPQQDMVRVKNRLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIGI 185
L+VCITEGIPQ DMVRVK+ L +Q KTRLIGPNCPGIIKP +CKIGIMP +IHKPGKIGI
Sbjct: 141 LIVCITEGIPQHDMVRVKHALNSQSKTRLIGPNCPGIIKPGECKIGIMPGYIHKPGKIGI 200
Query: 186 VSRSGTLTYEAVHQTSQVGLGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXXX 365
VSRSGTLTYEAV QT+ VGLGQS +GIGGDPFNGTNFVDCLE F D T+
Sbjct: 201 VSRSGTLTYEAVFQTTAVGLGQSTCVGIGGDPFNGTNFVDCLEKFFVDPQTEGIVLIGEI 260
Query: 366 XXXXXXXXXMYLEKHNAGPNRKAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKIDAL 545
++ A K VV+FIAGLTAPPGRRM Q+KI +L
Sbjct: 261 GGTAEEDAAALIK---ASGTEKPVVAFIAGLTAPPGRRMGHAGAIVSGGKGTAQDKIKSL 317
Query: 546 KHAGVIVTLSPAQMGASMIE 605
AGV V SPA++G++M E
Sbjct: 318 NDAGVKVVESPAKIGSAMYE 337
>sp|O13750|SUCA_SCHPO Probable succinyl-CoA ligase [GDP-forming] alpha-chain,
mitochondrial precursor (Succinyl-CoA synthetase, alpha
chain) (SCS-alpha)
Length = 331
Score = 217 bits (553), Expect = 2e-56
Identities = 114/209 (54%), Positives = 142/209 (67%), Gaps = 1/209 (0%)
Frame = +3
Query: 3 PLVVCITEGIPQQDMVRVKNRLINQEKTRLIGPNCPGIIKPNQCKIGIMPAHIHKPGKIG 182
PL+V ITEGIPQ DM+RV + L Q K+RL+GPNCPGII+P QCKIGIMP+HIHKPG IG
Sbjct: 123 PLIVAITEGIPQHDMLRVSDILKTQSKSRLVGPNCPGIIRPGQCKIGIMPSHIHKPGCIG 182
Query: 183 IVSRSGTLTYEAVHQTSQVGLGQSLVIGIGGDPFNGTNFVDCLEVFVRDEHTKXXXXXXX 362
IVSRSGTLTYEAV+QT+Q LGQSLVIGIGGDPF GTNF+D L++F+ D +T+
Sbjct: 183 IVSRSGTLTYEAVNQTTQTDLGQSLVIGIGGDPFPGTNFIDALKLFLDDPNTQGIILIGE 242
Query: 363 XXXXXXXXXXMYLEKHNAGPNR-KAVVSFIAGLTAPPGRRMXXXXXXXXXXXXXXQEKID 539
++ NA + K VVSFIAG TAP GRRM K +
Sbjct: 243 IGGSAEEDAAEFIRAANASRSTPKPVVSFIAGATAPKGRRMGHAGAIVAGGKGTAAAKFE 302
Query: 540 ALKHAGVIVTLSPAQMGASMIEALHKLSN 626
AL+ AGV ++ SPA +G+ ++E L+KL +
Sbjct: 303 ALEAAGVRISRSPATLGSLIVEELNKLKH 331
>sp|O19069|SUCA_PIG Succinyl-CoA ligase [GDP-forming] alpha-chain, mitochondrial
precursor (Succinyl-CoA synthetase, alpha chain)
(SCS-alpha)
Length = 350
Score = 214 bits (544), Expect = 3e-55
Identities = 118/226 (52%), Positives = 144/226 (63%), Gaps = 21/226 (9%)
Frame = +3
Query: 3 PLVVCITEGIPQQDMVRVKNRLINQEKTRLIGPNCPGII-------------------KP 125
PLVVCITEGIPQQDMVRVK+RL+ Q KTRLIGPNCPG+I +
Sbjct: 125 PLVVCITEGIPQQDMVRVKHRLLRQGKTRLIGPNCPGVINRFLRFAVYITSRVFTCTQQE 184
Query: 126 NQCKIGIM--PAHIHKPGKIGIVSRSGTLTYEAVHQTSQVGLGQSLVIGIGGDPFNGTNF 299
KI ++ IH +GIVSRSGTLTYEAVHQT+QVGLGQSL +GIGGDPFNGT+F
Sbjct: 185 EYRKIPLLFGTRSIH----MGIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDF 240
Query: 300 VDCLEVFVRDEHTKXXXXXXXXXXXXXXXXXMYLEKHNAGPNRKAVVSFIAGLTAPPGRR 479
DCLE+F+ D T+ +L++HN+GP K VVSFIAGLTAPPGRR
Sbjct: 241 TDCLEIFLNDPATEGIILIGEIGGNAEENAAEFLKQHNSGPKSKPVVSFIAGLTAPPGRR 300
Query: 480 MXXXXXXXXXXXXXXQEKIDALKHAGVIVTLSPAQMGASMIEALHK 617
M +EKI AL+ AGV+V++SPAQ+G ++ + K
Sbjct: 301 MGHAGAIIAGGKGGAKEKITALQSAGVVVSMSPAQLGTTIYKEFEK 346
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,611,142
Number of Sequences: 369166
Number of extensions: 1818054
Number of successful extensions: 4241
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4061
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4177
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7115329200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)