Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_L19
(693 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O61369|PICO_DROAN Putative inorganic phosphate cotranspo... 161 1e-39
sp|Q9NRA2|S17A5_HUMAN Sialin (Solute carrier family 17 memb... 159 5e-39
sp|Q9V7S5|PICO_DROME Putative inorganic phosphate cotranspo... 159 9e-39
sp|Q9MZD1|S17A5_SHEEP Sialin (Solute carrier family 17 memb... 155 1e-37
sp|Q8BN82|S17A5_MOUSE Sialin (Solute carrier family 17 memb... 155 1e-37
sp|Q03567|YLD2_CAEEL Hypothetical protein C38C10.2 in chrom... 144 2e-34
sp|P34644|YOQ6_CAEEL Hypothetical protein ZK512.6 in chromo... 103 3e-22
sp|O00624|NPT3_HUMAN Sodium-dependent phosphate transport p... 101 2e-21
sp|Q28722|NPT1_RABIT Renal sodium-dependent phosphate trans... 98 2e-20
sp|Q61983|NPT1_MOUSE Renal sodium-dependent phosphate trans... 92 2e-18
>sp|O61369|PICO_DROAN Putative inorganic phosphate cotransporter
Length = 483
Score = 161 bits (408), Expect = 1e-39
Identities = 85/225 (37%), Positives = 119/225 (52%), Gaps = 1/225 (0%)
Frame = +3
Query: 21 FLGFAVVYVLRVNLSVAILAMVNSSALNEKGVNFTPECPVSKSLTNKTGNGEFVWSQEIQ 200
FLG A YV+R N+SVAI+AMVN +A+ + EC + + +GEF W+ +Q
Sbjct: 3 FLGMANAYVMRTNMSVAIVAMVNHTAIKSGEEEYDDECGDRDIPIDDSQDGEFPWNAALQ 62
Query: 201 GIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXXAARAGYGW-LIAL 377
G IL +FF+GY+ Q+P G +A K G F G G+ AAR G W L A+
Sbjct: 63 GYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAAREGGVWGLCAV 122
Query: 378 RVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXXXXDANVMG 557
R ++G GE P H ML W P E + +G VY+G+ + G
Sbjct: 123 RFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGFDG 182
Query: 558 GWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESS 692
GWPS+FY+ GIVG +W I + Y P+ HP+I E+EK++I S
Sbjct: 183 GWPSIFYVFGIVGTVWSIAFLIFVYEDPSTHPKIDEREKKYINES 227
>sp|Q9NRA2|S17A5_HUMAN Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid
cotransporter) (AST) (Membrane glycoprotein HP59)
Length = 495
Score = 159 bits (403), Expect = 5e-39
Identities = 93/233 (39%), Positives = 123/233 (52%), Gaps = 4/233 (1%)
Frame = +3
Query: 6 ISIWGFLGFAVVYVLRVNLSVAILAMVNSSALNEKGVNFTPECPVS----KSLTNKTGNG 173
++I F GF +VY LRVNLSVA++ MV+S+ E + CP K N+TG
Sbjct: 42 LAILAFFGFFIVYALRVNLSVALVDMVDSNTTLEDN-RTSKACPEHSAPIKVHHNQTGK- 99
Query: 174 EFVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXXAARA 353
++ W E QG ILG+FF+GYI Q+P G +A KIGGK G G+ AA
Sbjct: 100 KYQWDAETQGWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGILGTAVLTLFTPIAADL 159
Query: 354 GYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXX 533
G G LI LR LEG GE +T+PAMH M WAP +E + + I Y+G+
Sbjct: 160 GVGPLIVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLSISYAGAQLGTVISLPLSGI 219
Query: 534 XXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESS 692
W VFY G +G+ WF++W ++ TP H RIS EK +I SS
Sbjct: 220 IC---YYMNWTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKRISHYEKEYILSS 269
>sp|Q9V7S5|PICO_DROME Putative inorganic phosphate cotransporter
Length = 529
Score = 159 bits (401), Expect = 9e-39
Identities = 85/226 (37%), Positives = 119/226 (52%), Gaps = 2/226 (0%)
Frame = +3
Query: 21 FLGFAVVYVLRVNLSVAILAMVNSSALNE-KGVNFTPECPVSKSLTNKTGNGEFVWSQEI 197
FLG A YV+R N+SVAI+AMVN +A+ + + EC + + +GEF WS +
Sbjct: 48 FLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDDSQDGEFAWSSAL 107
Query: 198 QGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXXAARAGYGW-LIA 374
QG IL +FF+GY+ Q+P G +A K G F G G+ AAR G W L A
Sbjct: 108 QGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGLCA 167
Query: 375 LRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXXXXDANVM 554
+R ++G GE P H ML W P E + +G VY+G+ +
Sbjct: 168 VRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGFD 227
Query: 555 GGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESS 692
GGWPS+FY+ GIVG +W I + + P+ HP I E+EK++I S
Sbjct: 228 GGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYINDS 273
>sp|Q9MZD1|S17A5_SHEEP Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid
cotransporter) (Membrane glycoprotein SP55)
Length = 495
Score = 155 bits (391), Expect = 1e-37
Identities = 91/232 (39%), Positives = 120/232 (51%), Gaps = 3/232 (1%)
Frame = +3
Query: 6 ISIWGFLGFAVVYVLRVNLSVAILAMVNSSAL---NEKGVNFTPECPVSKSLTNKTGNGE 176
++ F GF V+Y LRVNLSVA++ MV+S+ N K L N+TG +
Sbjct: 42 LAFLSFFGFFVLYSLRVNLSVALVDMVDSNTTAKDNRTSYECAEHSAPIKVLHNQTGK-K 100
Query: 177 FVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXXAARAG 356
+ W E QG ILG+FF+GYI Q+P G +A + GGK G G+ AA G
Sbjct: 101 YRWDAETQGWILGSFFYGYIITQIPGGYVASRSGGKLLLGFGIFATAIFTLFTPLAADFG 160
Query: 357 YGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXXX 536
G L+ALR LEG GE +TYPAMH M WAP +E + + I Y+G+
Sbjct: 161 VGALVALRALEGLGEGVTYPAMHAMWSSWAPPLERSKLLSISYAGAQLGTVVSLPLSGVI 220
Query: 537 XDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESS 692
W VFY GIVG++WFI+W + TP H I+ EK +I SS
Sbjct: 221 C---YYMNWTYVFYFFGIVGIIWFILWICLVSDTPETHKTITPYEKEYILSS 269
>sp|Q8BN82|S17A5_MOUSE Sialin (Solute carrier family 17 member 5) (Sodium/sialic acid
cotransporter)
Length = 495
Score = 155 bits (391), Expect = 1e-37
Identities = 90/232 (38%), Positives = 121/232 (52%), Gaps = 3/232 (1%)
Frame = +3
Query: 6 ISIWGFLGFAVVYVLRVNLSVAILAMVNSSAL---NEKGVNFTPECPVSKSLTNKTGNGE 176
++I F GF V+Y LRVNLSVA++ MV+S+ N K N TG +
Sbjct: 42 LAILAFCGFFVLYALRVNLSVALVDMVDSNTTLTDNRTSKECAEHSAPIKVHHNHTGK-K 100
Query: 177 FVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXXAARAG 356
+ W E QG ILG+FF+GYI Q+P G IA ++GGK G+G+ AA G
Sbjct: 101 YKWDAETQGWILGSFFYGYIVTQIPGGYIASRVGGKLLLGLGILGTSVFTLFTPLAADLG 160
Query: 357 YGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXXX 536
L+ LR LEG GE +T+PAMH M WAP +E + + I Y+G+
Sbjct: 161 VVTLVVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLTISYAGAQLGTVISLPLSGII 220
Query: 537 XDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESS 692
W VFY+ GIVG++WFI+W ++ TP H IS EK +I SS
Sbjct: 221 C---YYMNWTYVFYLFGIVGIVWFILWMWIVSDTPETHKTISHYEKEYIVSS 269
>sp|Q03567|YLD2_CAEEL Hypothetical protein C38C10.2 in chromosome III
Length = 493
Score = 144 bits (363), Expect = 2e-34
Identities = 79/230 (34%), Positives = 118/230 (51%), Gaps = 4/230 (1%)
Frame = +3
Query: 6 ISIWGFLGFAVVYVLRVNLSVAILAMVNSSALNEKGVNFTPECPVSKSLTNKTGN----G 173
+S+ F G V Y++R N+S A++ MVN + + GV C K +T N G
Sbjct: 18 LSLVMFFGCLVTYMMRTNMSFAVVCMVNENK-TDTGVEKVSRC--GKEMTPVESNSSVIG 74
Query: 174 EFVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXXAARA 353
EF W ++ G++L +FF+GYI Q+ G +A + GGK + + AAR
Sbjct: 75 EFDWDKQTTGMVLSSFFYGYIGSQIIGGHLASRYGGKRVVFVTILGSALLTLLNPVAART 134
Query: 354 GYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXX 533
L LR G + T+PAMHTM W P +E + + G+ Y+G+
Sbjct: 135 SEYALAILRAAIGFLQGATFPAMHTMWSVWGPPLELSVLTGVTYAGAQIGNVIVLPLSGF 194
Query: 534 XXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFI 683
+ GGWPS+FYI G+ GVLW +W +V+ PA HPRI+ +EK++I
Sbjct: 195 LCEYGFDGGWPSIFYIIGVFGVLWTAVWWYVSSDKPATHPRITPEEKQYI 244
>sp|P34644|YOQ6_CAEEL Hypothetical protein ZK512.6 in chromosome III
Length = 576
Score = 103 bits (258), Expect = 3e-22
Identities = 62/231 (26%), Positives = 105/231 (45%), Gaps = 1/231 (0%)
Frame = +3
Query: 3 VISIWGFLGFAVVYVLRVNLSVAILAMVNSSALNEKGVNFTPECPVSKSLTNKTGNGEFV 182
+++I +GF + + +R N A M N+T K EF
Sbjct: 71 LLAILANMGFMISFGIRCNFGAAKTHMYK---------NYTDPY-------GKVHMHEFN 114
Query: 183 WSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXXAARAGYG 362
W+ + ++ ++F+GY+ Q+PAG +A K FG G+ +
Sbjct: 115 WTIDELSVMESSYFYGYLVTQIPAGFLAAKFPPNKLFGFGIGVGAFLNILLPYGFKVKSD 174
Query: 363 WLIA-LRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXXXX 539
+L+A +++ +G + + YPAMH + YWAP ME + + ++GS+
Sbjct: 175 YLVAFIQITQGLVQGVCYPAMHGVWRYWAPPMERSKLATTAFTGSYAGAVLGLPLSAFLV 234
Query: 540 DANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESS 692
W + FY+ G+ GV+W I+W V + PA HP IS++EK FIE +
Sbjct: 235 S---YVSWAAPFYLYGVCGVIWAILWFCVTFEKPAFHPTISQEEKIFIEDA 282
>sp|O00624|NPT3_HUMAN Sodium-dependent phosphate transport protein 3 (Sodium/phosphate
cotransporter 3) (Na(+)/PI cotransporter 3) (Solute
carrier family 18 member 2)
Length = 436
Score = 101 bits (251), Expect = 2e-21
Identities = 73/236 (30%), Positives = 109/236 (46%), Gaps = 9/236 (3%)
Frame = +3
Query: 12 IWGFLGFAVVYVLRVNLSVAILAMVNSSALNEKGV-NFTPECPVSKSLTNK--------T 164
I F F ++ RV+LS+AI+AMVN++ ++G+ N + E PV+ + N T
Sbjct: 23 IMHFSNFTMI-TQRVSLSIAIIAMVNTT--QQQGLSNASTEGPVADAFNNSSISIKEFDT 79
Query: 165 GNGEFVWSQEIQGIILGAFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXXA 344
+ WS E QGII + +G I +P+G +A G K G G+ A
Sbjct: 80 KASVYQWSPETQGIIFSSINYGIILTLIPSGYLAGIFGAKKMLGAGLLISSLLTLFTPLA 139
Query: 345 ARAGYGWLIALRVLEGAGESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXX 524
A G +I +R ++G + + + T+ WAP +E + + I SGS
Sbjct: 140 ADFGVILVIMVRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTTIAGSGSAFGSFIILCV 199
Query: 525 XXXXXDANVMGGWPSVFYIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESS 692
A WP +FYI G G + ++W V Y P HHP IS +EK I SS
Sbjct: 200 GGLISQAL---SWPFIFYIFGSTGCVCCLLWFTVIYDDPMHHPCISVREKEHILSS 252
>sp|Q28722|NPT1_RABIT Renal sodium-dependent phosphate transport protein 1
(Sodium/phosphate cotransporter 1) (Na(+)/PI
cotransporter 1) (Renal sodium-phosphate transport
protein 1) (Renal Na(+)-dependent phosphate
cotransporter 1) (Solute carrier family 18 member 1)
(NAPI-1)
Length = 465
Score = 98.2 bits (243), Expect = 2e-20
Identities = 65/219 (29%), Positives = 98/219 (44%)
Frame = +3
Query: 36 VVYVLRVNLSVAILAMVNSSALNEKGVNFTPECPVSKSLTNKTGNGEFVWSQEIQGIILG 215
V+ R+ LS+ ++AMVN++ L+ +P K L N T N + WS ++QGII
Sbjct: 30 VIIAQRMCLSLTMVAMVNNTNLHG-----SPNTSAEKRLDN-TKNPVYNWSPDVQGIIFS 83
Query: 216 AFFWGYIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXXAARAGYGWLIALRVLEGA 395
+ F+G +Q+P G I+ K G + AA G W+I RV++G
Sbjct: 84 SIFYGAFLIQIPVGYISGIYSIKKLIGFALFLSSLVSIFIPQAAAVGETWIIVCRVVQGI 143
Query: 396 GESITYPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXXXXDANVMGGWPSVF 575
+ A H + WAP +E + + SG ++ GWP VF
Sbjct: 144 TQGTVTTAQHEIWVKWAPPLERGRLTSMSLSGFLLGPFIVLLVTGIICESL---GWPMVF 200
Query: 576 YIPGIVGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESS 692
YI G G ++W + Y P HP +S EK +I SS
Sbjct: 201 YIFGACGCAVCLLWFVLYYDDPKDHPCVSLHEKEYITSS 239
>sp|Q61983|NPT1_MOUSE Renal sodium-dependent phosphate transport protein 1
(Sodium/phosphate cotransporter 1) (Na(+)/PI
cotransporter 1) (Renal sodium-phosphate transport
protein 1) (Renal Na(+)-dependent phosphate
cotransporter 1) (Solute carrier family 18 member 1)
Length = 465
Score = 91.7 bits (226), Expect = 2e-18
Identities = 63/214 (29%), Positives = 96/214 (44%)
Frame = +3
Query: 51 RVNLSVAILAMVNSSALNEKGVNFTPECPVSKSLTNKTGNGEFVWSQEIQGIILGAFFWG 230
RV L++ ++AMVN N + + E V + + N + WS +IQG+IL + F+G
Sbjct: 35 RVCLNLTMVAMVN----NTGSPHLSNESVVE--MLDNVKNPVYSWSPDIQGLILSSVFFG 88
Query: 231 YIPLQVPAGAIAVKIGGKWFFGIGVXXXXXXXXXXXXAARAGYGWLIALRVLEGAGESIT 410
+ +Q P G ++ K G + AA+ G +I RVL+G +
Sbjct: 89 MVVVQAPVGYLSGIYPMKRIIGSSLFLSSLMSLLIPPAAQVGAALVIVCRVLQGIAQGTV 148
Query: 411 YPAMHTMLGYWAPAMETTFIGGIVYSGSFXXXXXXXXXXXXXXDANVMGGWPSVFYIPGI 590
H + WAP +E + + SG D + GWP VFYI GI
Sbjct: 149 STGQHEIWVKWAPPLERGRLTSMTLSGFVMGPFIVLLVSGFICD---LLGWPMVFYIFGI 205
Query: 591 VGVLWFIIWSFVAYSTPAHHPRISEKEKRFIESS 692
VG + + W F+ + P HP +S EK +I SS
Sbjct: 206 VGCVLSLSWFFLFFDDPKDHPYMSSSEKDYIISS 239
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,862,723
Number of Sequences: 369166
Number of extensions: 1947949
Number of successful extensions: 5628
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5322
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5572
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5976365205
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)