Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_K09
(866 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P27636|CDC15_YEAST Cell division control protein 15 56 1e-07
sp|P41892|CDC7_SCHPO Cell division control protein 7 52 3e-06
sp|P26618|PGFRA_MOUSE Alpha platelet-derived growth factor ... 46 2e-04
sp|P18106|FPS_DROME Tyrosine-protein kinase Fps85D (dFer) 46 2e-04
sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 precursor (Tyr... 45 3e-04
sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 precursor (T... 45 3e-04
sp|P28582|CDPK_DAUCA Calcium-dependent protein kinase (CDPK) 45 3e-04
sp|Q8IR79|LIMK1_DROME LIM domain kinase 1 (LIMK-1) (dLIMK) 45 3e-04
sp|Q07494|EPHB1_CHICK Ephrin type-B receptor 1 (Tyrosine-pr... 45 3e-04
sp|P16234|PGFRA_HUMAN Alpha platelet-derived growth factor ... 44 4e-04
>sp|P27636|CDC15_YEAST Cell division control protein 15
Length = 974
Score = 55.8 bits (133), Expect = 1e-07
Identities = 33/93 (35%), Positives = 51/93 (54%)
Frame = +2
Query: 551 YIKHEELGHGPFGSVYRCSKFGSKDMVVLKKYKNPNDKDEELKKLMVEFSIYEKLGDHPR 730
Y + +G G +G VY+ + +V +K+ ND EEL +M E S+ + L +H
Sbjct: 25 YHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYEND--EELNDIMAEISLLKNL-NHNN 81
Query: 731 ILKCNGFFRSVKASYIKLDYMANGSLRSWLHKN 829
I+K +GF R YI L+Y ANGSLR + ++
Sbjct: 82 IVKYHGFIRKSYELYILLEYCANGSLRRLISRS 114
>sp|P41892|CDC7_SCHPO Cell division control protein 7
Length = 1062
Score = 51.6 bits (122), Expect = 3e-06
Identities = 30/82 (36%), Positives = 45/82 (54%)
Frame = +2
Query: 569 LGHGPFGSVYRCSKFGSKDMVVLKKYKNPNDKDEELKKLMVEFSIYEKLGDHPRILKCNG 748
LG G FG+VYR + + V +KK K +L + +E + + L DHP I+K G
Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNL-DHPNIVKYRG 73
Query: 749 FFRSVKASYIKLDYMANGSLRS 814
+++ + I L+Y NGSLRS
Sbjct: 74 SYQTNDSLCIILEYCENGSLRS 95
>sp|P26618|PGFRA_MOUSE Alpha platelet-derived growth factor receptor precursor
(PDGF-R-alpha)
Length = 1089
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/198 (25%), Positives = 81/198 (40%), Gaps = 21/198 (10%)
Frame = +2
Query: 299 RIEFTITLNCLVPEYGTVVAENIRCLNPLIHK---------VADTIEIPAKNITVYQDEN 451
++E TI + CL +VVA ++ + P + V I I + + V +
Sbjct: 492 KVEETIAVRCLAKNNLSVVARELKLVAPTLRSELTVAAAVLVLLVIVIVSLIVLVVIWKQ 551
Query: 452 KEK-QVKWDEDYEQLISGGKSISLFYLPTP-----DF--DDYIKHEELGHGPFGSVYRCS 607
K + +++W G + I + + P +F D + LG G FG V +
Sbjct: 552 KPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGT 611
Query: 608 KFG-SKDMVVLK---KYKNPNDKDEELKKLMVEFSIYEKLGDHPRILKCNGFFRSVKASY 775
+G S+ V+K K P + E + LM E I LG H I+ G Y
Sbjct: 612 AYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIY 671
Query: 776 IKLDYMANGSLRSWLHKN 829
I +Y G L ++LHKN
Sbjct: 672 IITEYCFYGDLVNYLHKN 689
>sp|P18106|FPS_DROME Tyrosine-protein kinase Fps85D (dFer)
Length = 1325
Score = 45.8 bits (107), Expect = 2e-04
Identities = 31/95 (32%), Positives = 48/95 (50%)
Frame = +2
Query: 545 DDYIKHEELGHGPFGSVYRCSKFGSKDMVVLKKYKNPNDKDEELKKLMVEFSIYEKLGDH 724
DD + E +G G FG VY+ +K S + V K DE+ +K + E I ++ DH
Sbjct: 1061 DDVVLLERIGRGNFGDVYK-AKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQY-DH 1118
Query: 725 PRILKCNGFFRSVKASYIKLDYMANGSLRSWLHKN 829
P I+K G + I ++ + GSL ++L KN
Sbjct: 1119 PNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKN 1153
>sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 precursor (Tyrosine-protein kinase
receptor EPH-2) (ELK)
Length = 984
Score = 44.7 bits (104), Expect = 3e-04
Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Frame = +2
Query: 551 YIKHEE-LGHGPFGSVY--RCSKFGSKDMVVLKKYKNPNDKDEELKKLMVEFSIYEKLGD 721
++K EE +G G FG VY R G +++ V K +++ + + E SI + D
Sbjct: 618 FVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQF-D 676
Query: 722 HPRILKCNGFFRSVKASYIKLDYMANGSLRSWLHKNGAQ 838
HP I++ G + I ++M NG+L S+L +N Q
Sbjct: 677 HPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQ 715
>sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 precursor (Tyrosine-protein kinase
receptor EPH-2) (NET) (HEK6) (ELK)
Length = 984
Score = 44.7 bits (104), Expect = 3e-04
Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Frame = +2
Query: 551 YIKHEE-LGHGPFGSVY--RCSKFGSKDMVVLKKYKNPNDKDEELKKLMVEFSIYEKLGD 721
++K EE +G G FG VY R G +++ V K +++ + + E SI + D
Sbjct: 618 FVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQF-D 676
Query: 722 HPRILKCNGFFRSVKASYIKLDYMANGSLRSWLHKNGAQ 838
HP I++ G + I ++M NG+L S+L +N Q
Sbjct: 677 HPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQ 715
>sp|P28582|CDPK_DAUCA Calcium-dependent protein kinase (CDPK)
Length = 532
Score = 44.7 bits (104), Expect = 3e-04
Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 5/91 (5%)
Frame = +2
Query: 551 YIKHEELGHGPFGSVYRCSKFGSKDM-----VVLKKYKNPNDKDEELKKLMVEFSIYEKL 715
Y +ELG G FG VY+C++ S + ++ +K + NDK E++K+ E I + L
Sbjct: 81 YTLGKELGRGQFGCVYQCTENSSGQLYACKSILKRKLVSKNDK-EDIKR---EIQILQHL 136
Query: 716 GDHPRILKCNGFFRSVKASYIKLDYMANGSL 808
P I++ G F ++ ++ ++ A G L
Sbjct: 137 SGQPNIVEFKGVFEDRQSVHLVMELCAGGEL 167
>sp|Q8IR79|LIMK1_DROME LIM domain kinase 1 (LIMK-1) (dLIMK)
Length = 1257
Score = 44.7 bits (104), Expect = 3e-04
Identities = 27/92 (29%), Positives = 48/92 (52%)
Frame = +2
Query: 548 DYIKHEELGHGPFGSVYRCSKFGSKDMVVLKKYKNPNDKDEELKKLMVEFSIYEKLGDHP 727
D + E+LG G FG V++ + S +++VLK+ DEE ++ ++ +L DH
Sbjct: 400 DLVIGEKLGEGFFGKVFKVTHRQSGEVMVLKELHRA---DEEAQRNFIKEVAVLRLLDHR 456
Query: 728 RILKCNGFFRSVKASYIKLDYMANGSLRSWLH 823
+LK G K ++ +Y+A G L+ +H
Sbjct: 457 HVLKFIGVLYKDKKLHMVTEYVAGGCLKELIH 488
>sp|Q07494|EPHB1_CHICK Ephrin type-B receptor 1 (Tyrosine-protein kinase receptor EPH-2)
(Tyrosine kinase CEK6 receptor)
Length = 984
Score = 44.7 bits (104), Expect = 3e-04
Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Frame = +2
Query: 551 YIKHEE-LGHGPFGSVY--RCSKFGSKDMVVLKKYKNPNDKDEELKKLMVEFSIYEKLGD 721
++K EE +G G FG VY R G +++ V K +++ + + E SI + D
Sbjct: 618 FVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQF-D 676
Query: 722 HPRILKCNGFFRSVKASYIKLDYMANGSLRSWLHKNGAQ 838
HP I++ G + I ++M NG+L S+L +N Q
Sbjct: 677 HPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQ 715
>sp|P16234|PGFRA_HUMAN Alpha platelet-derived growth factor receptor precursor
(PDGF-R-alpha) (CD140a antigen)
Length = 1089
Score = 44.3 bits (103), Expect = 4e-04
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 4/99 (4%)
Frame = +2
Query: 545 DDYIKHEELGHGPFGSVYRCSKFG-SKDMVVLK---KYKNPNDKDEELKKLMVEFSIYEK 712
D + LG G FG V + +G S+ V+K K P + E + LM E I
Sbjct: 591 DGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTH 650
Query: 713 LGDHPRILKCNGFFRSVKASYIKLDYMANGSLRSWLHKN 829
LG H I+ G YI +Y G L ++LHKN
Sbjct: 651 LGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKN 689
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,553,841
Number of Sequences: 369166
Number of extensions: 1758420
Number of successful extensions: 5505
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5285
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5459
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8550075140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)