Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_J09
(885 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P87137|YDM6_SCHPO Hypothetical protein C57A7.06 in chrom... 41 0.004
sp|Q9NZW4|DSPP_HUMAN Dentin sialophosphoprotein precursor [... 38 0.043
sp|O42970|YB95_SCHPO Hypothetical serine-rich protein C1E8.... 37 0.096
sp|Q9U9I5|SWA_DROPS Swallow protein 37 0.096
sp|Q14093|CYLC2_HUMAN Cylicin-2 (Cylicin II) (Multiple-band... 36 0.12
sp|Q14669|TRI12_HUMAN Thyroid receptor interacting protein ... 35 0.36
sp|P29148|Npre_PAEPO Bacillolysin precursor (Neutral protease) 34 0.47
sp|O15234|CASC3_HUMAN Cancer susceptibility candidate gene ... 34 0.62
sp|P32583|SRP40_YEAST Suppressor protein SRP40 33 0.81
sp|Q6KI49|RS3_MYCMO 30S ribosomal protein S3 33 0.81
>sp|P87137|YDM6_SCHPO Hypothetical protein C57A7.06 in chromosome I
Length = 929
Score = 41.2 bits (95), Expect = 0.004
Identities = 55/235 (23%), Positives = 94/235 (40%), Gaps = 31/235 (13%)
Frame = +1
Query: 13 QLEHDIIFMISDESPGREKMFVINPVTAENREQ---WVIQLRDIQRMQQDFLLALQDPKR 183
QLE+ I+ +ES G + + +N EQ + + D + + D +D KR
Sbjct: 24 QLENKILHSYEEESAGFD-----SEELEDNDEQGYSFGVNSEDDEEIDSDEAFDEEDEKR 78
Query: 184 FAS---------KVDSGGKDSNFLKPVSVSSRDGNSGSKKKQKWPTFNAGKSGSM----- 321
FA K + K+ N K +S++ D + S K N G GS
Sbjct: 79 FADWSFNASKSGKSNKDHKNLNNTKEISLNEEDDSDDSVNSDKLE--NEGSVGSSIDENE 136
Query: 322 ------LIKHLRPHSEKFADNSTVTSP----RGSSADRKGLHSDDKLSRINCLNTSDSEL 471
L+ + +P + ST+ P + D++ L D S N S+SEL
Sbjct: 137 LVDLDTLLDNDQPEKNESNTASTIRPPWIGNNDHATDKENLLESDASSS----NDSESEL 192
Query: 472 NKSPDSMSVNAKDMKKTTCDLLNDD----DSSAIKPRAYRSAFSFRLKRSKCDTK 624
S D+M+ + + + + D +DD DS R Y + + + K+ + D +
Sbjct: 193 TDSADNMNESDSESEIESSDSDHDDGENSDSKLDNLRNYIVSLNQKRKKDEADAE 247
>sp|Q9NZW4|DSPP_HUMAN Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein
(Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)]
Length = 1253
Score = 37.7 bits (86), Expect = 0.043
Identities = 47/209 (22%), Positives = 80/209 (38%), Gaps = 1/209 (0%)
Frame = +1
Query: 172 DPKRFASKVDSGGKDSNFLKPVSVSSRDGNSGSKKKQKWPTFNAGKSGSMLIKHLRPHSE 351
D + DS ++ S S D + S + N+ S +S
Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807
Query: 352 KFADNSTVTSPRGSSADRKGLHSDDKLSRINCLNTSDS-ELNKSPDSMSVNAKDMKKTTC 528
+D+S +S SS +S D N ++SDS + + S DS S N D ++
Sbjct: 808 DSSDSSD-SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDSSDSDSSNRSDSSNSS- 865
Query: 529 DLLNDDDSSAIKPRAYRSAFSFRLKRSKCDTKINTHCHSKSDELGVANSQPLSPGANTAP 708
D + DSS + S S + S ++ S SD +NS S +N++
Sbjct: 866 DSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD 925
Query: 709 VSATSHKKKGSNILHIFTSNRNKNKTPST 795
S +S+ SN S+ + + + S+
Sbjct: 926 SSESSNSSDNSNSSDSSNSSDSSDSSDSS 954
Score = 33.9 bits (76), Expect = 0.62
Identities = 46/215 (21%), Positives = 80/215 (37%), Gaps = 3/215 (1%)
Frame = +1
Query: 172 DPKRFASKVDSGGKDSNFLKPVSVSSRDGNSGSKKKQKWPTFNAGKSGSMLIKHLRPHSE 351
D ++ DS + S S D S S K + + + KS S S
Sbjct: 594 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSS--DSNSSDSS 651
Query: 352 KFADNSTVTSPRGSSADRKGLHSDDKLSRINCLNTSDSELNKSPDSMSVNAKDMKKTTCD 531
+D+S ++ SS S D S + ++SDS + S ++ + +
Sbjct: 652 DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSS 711
Query: 532 LLNDDDSSAIKPRAYRSAFSFRLKRSKCDTKINTHCHSKSDELGVAN---SQPLSPGANT 702
+D DSS S+ S S D+ ++ SD +N S S +N+
Sbjct: 712 DSSDSDSS-------DSSDSSNSNSSDSDSSNSSDSSDSSDSSDSSNSSDSSDSSDSSNS 764
Query: 703 APVSATSHKKKGSNILHIFTSNRNKNKTPSTPQNN 807
+ S +S S+ + SN + N + S+ +N
Sbjct: 765 SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799
Score = 32.7 bits (73), Expect = 1.4
Identities = 40/203 (19%), Positives = 74/203 (36%)
Frame = +1
Query: 199 DSGGKDSNFLKPVSVSSRDGNSGSKKKQKWPTFNAGKSGSMLIKHLRPHSEKFADNSTVT 378
DS DS+ + S D ++ S + ++ S +S +D+S +
Sbjct: 715 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 774
Query: 379 SPRGSSADRKGLHSDDKLSRINCLNTSDSELNKSPDSMSVNAKDMKKTTCDLLNDDDSSA 558
SS +S D N ++SDS + + S ++ + D N DSS
Sbjct: 775 DSSDSS------NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828
Query: 559 IKPRAYRSAFSFRLKRSKCDTKINTHCHSKSDELGVANSQPLSPGANTAPVSATSHKKKG 738
+ S S S ++ ++SD ++S S +N++ S +S
Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDSSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSS-- 886
Query: 739 SNILHIFTSNRNKNKTPSTPQNN 807
SN + N + S+ +N
Sbjct: 887 -------DSNESSNSSDSSDSSN 902
Score = 30.0 bits (66), Expect = 8.9
Identities = 44/207 (21%), Positives = 77/207 (37%)
Frame = +1
Query: 172 DPKRFASKVDSGGKDSNFLKPVSVSSRDGNSGSKKKQKWPTFNAGKSGSMLIKHLRPHSE 351
D +S DS + S S D ++ S+ + ++ S S S+
Sbjct: 673 DSSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS---------SD 723
Query: 352 KFADNSTVTSPRGSSADRKGLHSDDKLSRINCLNTSDSELNKSPDSMSVNAKDMKKTTCD 531
NS+ + SS S D + + ++SDS N S S S ++ D + D
Sbjct: 724 SSNSNSSDSDSSNSSDSSDSSDSSDSSNSSDSSDSSDSS-NSSDSSDSSDSSD----SSD 778
Query: 532 LLNDDDSSAIKPRAYRSAFSFRLKRSKCDTKINTHCHSKSDELGVANSQPLSPGANTAPV 711
N DS+ + S S S ++ S SD ++S S ++++
Sbjct: 779 SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838
Query: 712 SATSHKKKGSNILHIFTSNRNKNKTPS 792
S +S S+ +SNR+ + S
Sbjct: 839 SDSSDSSDSSDSSDSDSSNRSDSSNSS 865
>sp|O42970|YB95_SCHPO Hypothetical serine-rich protein C1E8.05 in chromosome II precursor
Length = 317
Score = 36.6 bits (83), Expect = 0.096
Identities = 34/138 (24%), Positives = 57/138 (41%), Gaps = 8/138 (5%)
Frame = +1
Query: 175 PKRFASKVDSGGKDSNFLKPVSVSSRDGNSGSKKKQKWPTFNAGKSGSMLIKHLRPHSEK 354
P +SK S K S+ S SS +S SK ++ S S S K
Sbjct: 165 PSSSSSKSSSSSKSSSSSSSSSKSSSSSSSSSKSSSS----SSSSSKSSASPSSSKSSSK 220
Query: 355 FADNSTVTS--PRGSS------ADRKGLHSDDKLSRINCLNTSDSELNKSPDSMSVNAKD 510
F+ +S +TS P SS ++ K +DD S + ++ S ++ + ++S +A
Sbjct: 221 FSSSSFITSTTPASSSSSGAIVSNAKTASTDDSSSASSATSSVSSVVSSASSALSASASS 280
Query: 511 MKKTTCDLLNDDDSSAIK 564
+ + D S A+K
Sbjct: 281 ASASVSSSASSDASPALK 298
>sp|Q9U9I5|SWA_DROPS Swallow protein
Length = 529
Score = 36.6 bits (83), Expect = 0.096
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Frame = +1
Query: 298 NAGKSGSMLIKHLRPHSEKFADNSTVTSPRGSSADRKGLHSDDK--LSRINCLNTSDSEL 471
NAGK L K+++PHS F+++ST P G+ G HS + SR N S+S
Sbjct: 339 NAGK----LKKNIQPHSLDFSNDSTEAEPNGNGTTSTG-HSSSRAITSRAAAPNNSESSH 393
Query: 472 NKSPDS-MSVNAKDMK 516
S DS + V A D++
Sbjct: 394 PSSNDSAIEVEALDLR 409
>sp|Q14093|CYLC2_HUMAN Cylicin-2 (Cylicin II) (Multiple-band polypeptide II)
Length = 348
Score = 36.2 bits (82), Expect = 0.12
Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 11/215 (5%)
Frame = +1
Query: 127 RDIQRMQQDFLLALQDPKRFASKVDSGGKDSNFLKPVSVSSRDGNSGSKKKQKWPTFNAG 306
+DI++ +++ L A +D K+ G KD+ K + S D G+KK K ++
Sbjct: 145 KDIEKGKEEKLDAKKDSKK-------GKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSN 197
Query: 307 KSGSMLIKHLRPHSEKFADNSTVTSPRGSSADRKGLHSDDKLSRINCLNTSD----SELN 474
K K SE + S +G +KG S +L + D + N
Sbjct: 198 KG-----KDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDAN 252
Query: 475 KSPDSMSV--NAKDMKKTTCD-----LLNDDDSSAIKPRAYRSAFSFRLKRSKCDTKINT 633
K +S +AK++KK D + D +K + + A K +K DT+ +
Sbjct: 253 KGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKES 312
Query: 634 HCHSKSDELGVANSQPLSPGANTAPVSATSHKKKG 738
K + N KKKG
Sbjct: 313 ADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKG 347
>sp|Q14669|TRI12_HUMAN Thyroid receptor interacting protein 12 (TRIP12)
Length = 1992
Score = 34.7 bits (78), Expect = 0.36
Identities = 40/191 (20%), Positives = 79/191 (41%), Gaps = 1/191 (0%)
Frame = +1
Query: 229 KPVSVSSRDGNSGSKKKQKWPTFNAGKSGSMLIKHLRPHSEKFADNSTVTSPRGSSADRK 408
K V +D + G K+ P +N S S K P + + ++ + T+ S + ++
Sbjct: 59 KTGQVPKKDNSRGVKRSAS-PDYNRTNSPSSAKK---PKALQHTESPSETNKPHSKSKKR 114
Query: 409 GLHSDDKLSRINCLNTSDSELNKSPDSMSVNAKDMKKTTCDLLNDDDSSAIKPRAYRSAF 588
L + +L +TS + KS + ++ K+T + S RSA
Sbjct: 115 HLDQEQQLKSAQSPSTSKAHTRKSGATGGSRSQKRKRTESSCVKSGSGSESTGAEERSAK 174
Query: 589 SFRLKRSKCDTKINTHCHSKSDELGVANSQPLSPGANTAPVSATSHKKKGSNILHIFTSN 768
+L SK T C + +D A++ +++A SA+S G+ + N
Sbjct: 175 PTKL-ASKSATSAKAGCSTITDSSSAASTS----SSSSAVASASSTVPPGARVKQGKDQN 229
Query: 769 R-NKNKTPSTP 798
+ ++++ S+P
Sbjct: 230 KARRSRSASSP 240
>sp|P29148|Npre_PAEPO Bacillolysin precursor (Neutral protease)
Length = 590
Score = 34.3 bits (77), Expect = 0.47
Identities = 38/162 (23%), Positives = 69/162 (42%), Gaps = 1/162 (0%)
Frame = +1
Query: 292 TFNAGKSGSMLIKHLRPHSEKFADNSTV-TSPRGSSADRKGLHSDDKLSRINCLNTSDSE 468
T + GKSG + +E + +T T+P+ S+++ + +RI L TSD
Sbjct: 110 TIHVGKSGEVTSYLGAVINEDQQEEATQGTTPKISASEAVYTAYKEAAARIEALPTSDDT 169
Query: 469 LNKSPDSMSVNAKDMKKTTCDLLNDDDSSAIKPRAYRSAFSFRLKRSKCDTKINTHCHSK 648
++K + S +KD T + N+D + ++ + S D+KI K
Sbjct: 170 ISKDAEEPSSVSKD---TYAEAANNDKTLSVD----KDELSLDKASVLKDSKIEAVEAEK 222
Query: 649 SDELGVANSQPLSPGANTAPVSATSHKKKGSNILHIFTSNRN 774
S +AN QP P + + KG ++L ++ + N
Sbjct: 223 SSIAKIANLQP-----EVDPKAELYYYPKGDDLLLVYVTEVN 259
>sp|O15234|CASC3_HUMAN Cancer susceptibility candidate gene 3 protein (Metastatic lymph
node protein 51) (MLN 51 protein) (Barentsz protein)
(Btz)
Length = 703
Score = 33.9 bits (76), Expect = 0.62
Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 14/144 (9%)
Frame = +1
Query: 136 QRMQQDFLLALQDPKRFASKVDSGGKDSNFLKPVSVSSRDGNSGSKKKQKWPTFNAGKSG 315
QR QD +D + AS DSGG S S+ G SGS Q+ G++G
Sbjct: 7 QRASQD----TEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQR-----GGRTG 57
Query: 316 SMLIKHLRPHSEKFADNSTVTSPRGSSAD--------------RKGLHSDDKLSRINCLN 453
++ ++ + K A+ S S G D +G +S+++ S++ +
Sbjct: 58 ALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKS 117
Query: 454 TSDSELNKSPDSMSVNAKDMKKTT 525
++ +N S K K+T
Sbjct: 118 EANDAVNSSTKEEKGEEKPDTKST 141
>sp|P32583|SRP40_YEAST Suppressor protein SRP40
Length = 406
Score = 33.5 bits (75), Expect = 0.81
Identities = 48/236 (20%), Positives = 86/236 (36%), Gaps = 32/236 (13%)
Frame = +1
Query: 199 DSGGKDSNFLKPVSVSSRDGNSGSKKKQKWPTFNAGKSGSMLIKHLRPHSEKFADNSTV- 375
DS +S+ S SS +S S+ + + ++G S S SE +++ T
Sbjct: 69 DSSDSESSSSSSSSSSSSSSSSDSESSSESDSSSSGSSSSSSSSSDESSSESESEDETKK 128
Query: 376 -----------------TSPRGSSADRKGLHSDDKLSRINCLNTSDSELNKSPDSMSVNA 504
T P SS+ S + SDS+ + S S S +
Sbjct: 129 RARESDNEDAKETKKAKTEPESSSSSESSSSGSSSSSESESGSESDSDSSSSSSSSSDSE 188
Query: 505 KDMK--------KTTCDLLNDDDSSAIKPRAYRSAFSFRLKRSKCDTKINTHCHSKSDEL 660
D + ++ D +D DSS+ + S S S D+ ++ S SD
Sbjct: 189 SDSESDSQSSSSSSSSDSSSDSDSSS-SDSSSDSDSSSSSSSSSSDSDSDSDSSSDSDSS 247
Query: 661 GVANSQPLSPGANTAPVSATSHKKK------GSNILHIFTSNRNKNKTPSTPQNND 810
G ++S S ++ S+ S S+ L + +++K TP +++
Sbjct: 248 GSSDSSSSSDSSSDESTSSDSSDSDSDSDSGSSSELETKEATADESKAEETPASSN 303
Score = 32.3 bits (72), Expect = 1.8
Identities = 45/197 (22%), Positives = 79/197 (40%), Gaps = 5/197 (2%)
Frame = +1
Query: 202 SGGKDSNFLKPVSVSSRDGNSGSKKKQKWPTFNAGKSGSMLIKHLRPHSEKFADNSTVTS 381
SG S+ + S S D +S S + S S S + +S +S
Sbjct: 159 SGSSSSSESESGSESDSDSSSSS----------SSSSDSESDSESDSQSSSSSSSSDSSS 208
Query: 382 PRGSSADRKGLHSDDKLSRINCLNTSDSELNKSPDSMSVNAKDMKKTTCDLLNDDDSSAI 561
SS+ SD S + + SDS+ + S DS S + D ++ D +D+ +S+
Sbjct: 209 DSDSSSSDSSSDSDSSSSSSSSSSDSDSDSDSSSDSDSSGSSD-SSSSSDSSSDESTSSD 267
Query: 562 KPRAYRSAFSFRLKRSKCDTKINTHCHSKSDELGVANSQPL-----SPGANTAPVSATSH 726
+ + S S+ +TK T SK++E ++++ S AN + A +
Sbjct: 268 SSDSDSDSDSG--SSSELETKEATADESKAEETPASSNESTPSASSSSSANKLNIPAGTD 325
Query: 727 KKKGSNILHIFTSNRNK 777
+ K H +R+K
Sbjct: 326 EIKEGQRKHFSRVDRSK 342
Score = 32.0 bits (71), Expect = 2.4
Identities = 37/170 (21%), Positives = 63/170 (37%), Gaps = 4/170 (2%)
Frame = +1
Query: 238 SVSSRDGNSGSKKKQKWPTFNAGKSGSMLIKHLRPHSEKFADNSTVTSPRGSSADRKGLH 417
S SS +SGS + + + S S SE +++ + +S SS+D
Sbjct: 151 SSSSESSSSGSSSSSESESGSESDSDSSSSSSSSSDSESDSESDSQSSSSSSSSDSS--- 207
Query: 418 SDDKLSRINCLNTSDSELNKSPDSMSVNAKDMKKTTCDLLNDDDSSAIKPRAYRSAFSFR 597
SD S + + SDS + S S ++ + D DSS+ + + S
Sbjct: 208 SDSDSSSSDSSSDSDSSSSSSSSSSDSDSDSDSSSDSDSSGSSDSSSSSDSSSDESTSSD 267
Query: 598 LKRSKCDTKINTHCHSKSDEL----GVANSQPLSPGANTAPVSATSHKKK 735
S D+ + ++ E A P S +T S++S K
Sbjct: 268 SSDSDSDSDSGSSSELETKEATADESKAEETPASSNESTPSASSSSSANK 317
>sp|Q6KI49|RS3_MYCMO 30S ribosomal protein S3
Length = 225
Score = 33.5 bits (75), Expect = 0.81
Identities = 27/108 (25%), Positives = 54/108 (50%)
Frame = +2
Query: 119 FNLGIFKECNKISY*HSKTRKDLLVKLILEEKIPIF*NQYQFHLVMEILALKRNKNGRLS 298
F G+ K+ N + Y K D+L++ ++KI F N++ ++ + ++RN+NG LS
Sbjct: 10 FRYGVTKKHNTLWYADKKDFADILLQ---DDKIYRFFNKFTREYLIGKVEIRRNQNGHLS 66
Query: 299 MLEKVGVC*LNIYGHTVKNLPIIQQLPHPEEVARIEKDCTLMINYQEL 442
+L H+ K I+ Q + E + ++ +D ++ +EL
Sbjct: 67 VLV-----------HSAKPGAILGQ--NGENINKLTQDIQKLLRNKEL 101
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.315 0.129 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,850,059
Number of Sequences: 369166
Number of extensions: 1944254
Number of successful extensions: 5152
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4907
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5125
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8838279920
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)