Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_I23
(655 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q19958|STO2_CAEEL Stomatin protein 2 125 1e-28
sp|Q27433|MEC2_CAEEL Mechanosensory protein 2 119 9e-27
sp|P27105|STOM_HUMAN Erythrocyte band 7 integral membrane p... 116 4e-26
sp|P54116|STOM_MOUSE Erythrocyte band 7 integral membrane p... 112 1e-24
sp|Q22165|STO4_CAEEL Stomatin protein 4 110 2e-24
sp|Q8TAV4|STML3_HUMAN Stomatin-like protein 3 109 7e-24
sp|Q6PE84|STML3_MOUSE Stomatin-like protein 3 (Stomatin-rel... 109 7e-24
sp|Q19200|STO1_CAEEL Stomatin protein 1 106 5e-23
sp|Q21190|UNC1_CAEEL Uncoordinated protein 1 (Protein unc-1) 104 2e-22
sp|Q20657|STO3_CAEEL Stomatin protein 3 93 7e-19
>sp|Q19958|STO2_CAEEL Stomatin protein 2
Length = 314
Score = 125 bits (314), Expect = 1e-28
Identities = 71/149 (47%), Positives = 98/149 (65%)
Frame = +2
Query: 176 HYRIFDPVMSVVNVEDANRSTRLLAQTTLRYVLGTVDLYSLFTDREDIAASMQETLDMAT 355
+YRI + +SV NVE+A+ STRLLAQTTLR +LGT L + +DRE +AASMQ LD AT
Sbjct: 162 YYRISNATVSVANVENAHHSTRLLAQTTLRNMLGTRSLSEILSDRETLAASMQTILDEAT 221
Query: 356 DAWGMKVERVEVKDVRIPMQLQXXXXXXXXXXXXXXXXVIAAEGEQKSSKAFKNSCRKRL 535
++WG+KVERVE+KDVR+P+QLQ VIAAEGEQK+S+A +++ +
Sbjct: 222 ESWGIKVERVEIKDVRLPIQLQRAMAAEAEATREARAKVIAAEGEQKASRALRDAA-SVI 280
Query: 536 YKCPISLQFEIFTNI*IVYQQRKNFNNHL 622
+ P +LQ + V R+ F++HL
Sbjct: 281 AQSPAALQLRYLQTLNSV--AREKFDDHL 307
Score = 48.9 bits (115), Expect = 1e-05
Identities = 18/34 (52%), Positives = 28/34 (82%)
Frame = +3
Query: 42 GAGLIFILPCLDSMKRIDLRTLTFDVPTQEVLTR 143
G G+ F+LPC++S ++DLRT++F VP QE+LT+
Sbjct: 117 GPGIFFVLPCIESYTKVDLRTVSFSVPPQEILTK 150
>sp|Q27433|MEC2_CAEEL Mechanosensory protein 2
Length = 481
Score = 119 bits (297), Expect = 9e-27
Identities = 66/128 (51%), Positives = 86/128 (67%)
Frame = +2
Query: 176 HYRIFDPVMSVVNVEDANRSTRLLAQTTLRYVLGTVDLYSLFTDREDIAASMQETLDMAT 355
++RI + +SV NVEDA RST+LLAQTTLR +LGT L + +DRE I+ MQ TLD AT
Sbjct: 210 YFRISNATISVTNVEDAARSTKLLAQTTLRNILGTKTLAEMLSDREAISHQMQTTLDEAT 269
Query: 356 DAWGMKVERVEVKDVRIPMQLQXXXXXXXXXXXXXXXXVIAAEGEQKSSKAFKNSCRKRL 535
+ WG+KVERVEVKDVR+P+QLQ VI AEGEQK+S+A K + + +
Sbjct: 270 EPWGVKVERVEVKDVRLPVQLQRAMAAEAEAAREARAKVIVAEGEQKASRALKEAA-EVI 328
Query: 536 YKCPISLQ 559
+ P +LQ
Sbjct: 329 AESPSALQ 336
Score = 48.1 bits (113), Expect = 2e-05
Identities = 17/34 (50%), Positives = 29/34 (85%)
Frame = +3
Query: 42 GAGLIFILPCLDSMKRIDLRTLTFDVPTQEVLTR 143
G G+ FI+PC+D+ +++DLR L+F+VP QE+L++
Sbjct: 165 GPGIFFIVPCIDTYRKVDLRVLSFEVPPQEILSK 198
>sp|P27105|STOM_HUMAN Erythrocyte band 7 integral membrane protein (Stomatin) (Protein
7.2b)
Length = 288
Score = 116 bits (291), Expect = 4e-26
Identities = 59/115 (51%), Positives = 81/115 (70%)
Frame = +2
Query: 176 HYRIFDPVMSVVNVEDANRSTRLLAQTTLRYVLGTVDLYSLFTDREDIAASMQETLDMAT 355
+YR+ + ++V N+ +A+ +TRLLAQTTLR VLGT +L + +DRE+IA +MQ TLD AT
Sbjct: 123 YYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDREEIAHNMQSTLDDAT 182
Query: 356 DAWGMKVERVEVKDVRIPMQLQXXXXXXXXXXXXXXXXVIAAEGEQKSSKAFKNS 520
DAWG+KVERVE+KDV++P+QLQ VIAAEGE +S+A K +
Sbjct: 183 DAWGIKVERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEA 237
Score = 51.6 bits (122), Expect = 2e-06
Identities = 20/34 (58%), Positives = 28/34 (82%)
Frame = +3
Query: 42 GAGLIFILPCLDSMKRIDLRTLTFDVPTQEVLTR 143
G GL FILPC DS ++D+RT++FD+P QE+LT+
Sbjct: 78 GPGLFFILPCTDSFIKVDMRTISFDIPPQEILTK 111
>sp|P54116|STOM_MOUSE Erythrocyte band 7 integral membrane protein (Stomatin) (Protein
7.2b)
Length = 284
Score = 112 bits (279), Expect = 1e-24
Identities = 57/115 (49%), Positives = 78/115 (67%)
Frame = +2
Query: 176 HYRIFDPVMSVVNVEDANRSTRLLAQTTLRYVLGTVDLYSLFTDREDIAASMQETLDMAT 355
+YR+ + ++V N+ +A+ +TRLLAQTTLR LGT +L + +DRE+IA MQ TLD AT
Sbjct: 123 YYRVQNATLAVANITNADSATRLLAQTTLRNALGTKNLSQILSDREEIAHHMQSTLDDAT 182
Query: 356 DAWGMKVERVEVKDVRIPMQLQXXXXXXXXXXXXXXXXVIAAEGEQKSSKAFKNS 520
D WG+KVERVE+KDV++P+QLQ VIAAEGE +S+A K +
Sbjct: 183 DDWGIKVERVEIKDVKLPVQLQRAMAAEAEAAREARAKVIAAEGEMNASRALKEA 237
Score = 52.0 bits (123), Expect = 1e-06
Identities = 21/34 (61%), Positives = 28/34 (82%)
Frame = +3
Query: 42 GAGLIFILPCLDSMKRIDLRTLTFDVPTQEVLTR 143
G GL FILPC DS ++D+RT++FD+P QEVLT+
Sbjct: 78 GPGLFFILPCTDSFIKVDMRTISFDIPPQEVLTK 111
>sp|Q22165|STO4_CAEEL Stomatin protein 4
Length = 281
Score = 110 bits (276), Expect = 2e-24
Identities = 61/144 (42%), Positives = 87/144 (60%)
Frame = +2
Query: 176 HYRIFDPVMSVVNVEDANRSTRLLAQTTLRYVLGTVDLYSLFTDREDIAASMQETLDMAT 355
++RI + +SV+NVEDA RST+LLAQTTLR LGT L + + R+ I+ MQ LD AT
Sbjct: 119 YFRISNATVSVINVEDAARSTKLLAQTTLRNFLGTRTLAEMLSSRDAISMQMQAALDEAT 178
Query: 356 DAWGMKVERVEVKDVRIPMQLQXXXXXXXXXXXXXXXXVIAAEGEQKSSKAFKNSCRKRL 535
D WG+KVERVE+KDVR+P+QLQ +IAAEGEQ +S+A ++ +
Sbjct: 179 DPWGVKVERVEIKDVRLPIQLQRAMAAEAEAARAAGAKIIAAEGEQLASRALADAA-DVI 237
Query: 536 YKCPISLQFEIFTNI*IVYQQRKN 607
P ++Q + + ++ N
Sbjct: 238 ATSPCAIQLRYLQTLNSISSEKNN 261
Score = 50.4 bits (119), Expect = 4e-06
Identities = 19/34 (55%), Positives = 29/34 (85%)
Frame = +3
Query: 42 GAGLIFILPCLDSMKRIDLRTLTFDVPTQEVLTR 143
G G+ FI+PC++S K+IDLR ++FDVP QE+L++
Sbjct: 74 GPGIFFIIPCIESFKKIDLRVVSFDVPPQEILSK 107
>sp|Q8TAV4|STML3_HUMAN Stomatin-like protein 3
Length = 291
Score = 109 bits (272), Expect = 7e-24
Identities = 63/144 (43%), Positives = 86/144 (59%)
Frame = +2
Query: 176 HYRIFDPVMSVVNVEDANRSTRLLAQTTLRYVLGTVDLYSLFTDREDIAASMQETLDMAT 355
+YRI+ V +V NV D +++T LLAQTTLR VLGT L + RE+IA S+Q LD AT
Sbjct: 120 YYRIYSAVSAVANVNDVHQATFLLAQTTLRNVLGTQTLSQILAGREEIAHSIQTLLDDAT 179
Query: 356 DAWGMKVERVEVKDVRIPMQLQXXXXXXXXXXXXXXXXVIAAEGEQKSSKAFKNSCRKRL 535
+ WG++V RVE+KDVRIP+QLQ V+AAEGE +SK+ K S L
Sbjct: 180 ELWGIRVARVEIKDVRIPVQLQRSMAAEAEATREARAKVLAAEGEMNASKSLK-SASMVL 238
Query: 536 YKCPISLQFEIFTNI*IVYQQRKN 607
+ PI+LQ + V ++ +
Sbjct: 239 AESPIALQLRYLQTLSTVATEKNS 262
Score = 47.8 bits (112), Expect = 3e-05
Identities = 19/34 (55%), Positives = 27/34 (79%)
Frame = +3
Query: 42 GAGLIFILPCLDSMKRIDLRTLTFDVPTQEVLTR 143
G GLI +LPC+D ++DLRT+T ++P QE+LTR
Sbjct: 75 GPGLILVLPCIDVFVKVDLRTVTCNIPPQEILTR 108
>sp|Q6PE84|STML3_MOUSE Stomatin-like protein 3 (Stomatin-related olfactory protein)
Length = 287
Score = 109 bits (272), Expect = 7e-24
Identities = 62/144 (43%), Positives = 87/144 (60%)
Frame = +2
Query: 176 HYRIFDPVMSVVNVEDANRSTRLLAQTTLRYVLGTVDLYSLFTDREDIAASMQETLDMAT 355
+YRI+ V +V NV D +++T LLAQTTLR VLGT L + + RE+IA S+Q LD AT
Sbjct: 116 YYRIYSAVSAVANVNDVHQATFLLAQTTLRNVLGTQTLSQILSGREEIAHSIQTLLDDAT 175
Query: 356 DAWGMKVERVEVKDVRIPMQLQXXXXXXXXXXXXXXXXVIAAEGEQKSSKAFKNSCRKRL 535
+ WG++V RVE+KDVRIP+QLQ V+AAEGE +SK+ K S L
Sbjct: 176 ELWGIRVARVEIKDVRIPVQLQRSMAAEAEATREARAKVLAAEGEMNASKSLK-SASMVL 234
Query: 536 YKCPISLQFEIFTNI*IVYQQRKN 607
+ P++LQ + V ++ +
Sbjct: 235 AESPVALQLRYLQTLTTVATEKNS 258
Score = 47.8 bits (112), Expect = 3e-05
Identities = 19/34 (55%), Positives = 27/34 (79%)
Frame = +3
Query: 42 GAGLIFILPCLDSMKRIDLRTLTFDVPTQEVLTR 143
G GLI +LPC+D ++DLRT+T ++P QE+LTR
Sbjct: 71 GPGLILVLPCIDVFVKVDLRTVTCNIPPQEILTR 104
>sp|Q19200|STO1_CAEEL Stomatin protein 1
Length = 330
Score = 106 bits (265), Expect = 5e-23
Identities = 54/111 (48%), Positives = 76/111 (68%)
Frame = +2
Query: 176 HYRIFDPVMSVVNVEDANRSTRLLAQTTLRYVLGTVDLYSLFTDREDIAASMQETLDMAT 355
++++FDP+ SVV V +A ST+LLAQTTLR +LGT L + +DRE I+A M+ +LD AT
Sbjct: 132 YFKVFDPITSVVGVGNATDSTKLLAQTTLRTILGTHTLSEILSDREKISADMKISLDEAT 191
Query: 356 DAWGMKVERVEVKDVRIPMQLQXXXXXXXXXXXXXXXXVIAAEGEQKSSKA 508
+ WG+KVERVE++DVR+P Q+Q +IAAEGE ++S A
Sbjct: 192 EPWGIKVERVELRDVRLPSQMQRAMAAEAEATRDAGAKIIAAEGELRASAA 242
Score = 45.4 bits (106), Expect = 1e-04
Identities = 17/34 (50%), Positives = 27/34 (79%)
Frame = +3
Query: 42 GAGLIFILPCLDSMKRIDLRTLTFDVPTQEVLTR 143
G G+ FI+PC+D+ IDLR +++VP+QE+L+R
Sbjct: 87 GPGIFFIIPCIDTFLNIDLRVASYNVPSQEILSR 120
>sp|Q21190|UNC1_CAEEL Uncoordinated protein 1 (Protein unc-1)
Length = 285
Score = 104 bits (260), Expect = 2e-22
Identities = 59/128 (46%), Positives = 78/128 (60%)
Frame = +2
Query: 176 HYRIFDPVMSVVNVEDANRSTRLLAQTTLRYVLGTVDLYSLFTDREDIAASMQETLDMAT 355
++R DP+ SV NV+DA ST+LLAQTTLR LG L + T+RE IA + LD T
Sbjct: 124 YFRTSDPIASVNNVDDAIYSTKLLAQTTLRNALGMKTLTEMLTEREAIAQLCETILDEGT 183
Query: 356 DAWGMKVERVEVKDVRIPMQLQXXXXXXXXXXXXXXXXVIAAEGEQKSSKAFKNSCRKRL 535
+ WG+KVERVEVKD+R+P QL V+AAEGEQK+S+A K + +
Sbjct: 184 EHWGVKVERVEVKDIRLPQQLTRAMAAEAEAAREARAKVVAAEGEQKASRALKEAA-DVI 242
Query: 536 YKCPISLQ 559
P++LQ
Sbjct: 243 QANPVALQ 250
Score = 46.6 bits (109), Expect = 6e-05
Identities = 17/34 (50%), Positives = 29/34 (85%)
Frame = +3
Query: 42 GAGLIFILPCLDSMKRIDLRTLTFDVPTQEVLTR 143
G G+IFI+PC+D+ ++IDLR +++ VP QE+L++
Sbjct: 79 GPGMIFIIPCIDTYRKIDLRVVSYAVPPQEILSK 112
>sp|Q20657|STO3_CAEEL Stomatin protein 3
Length = 267
Score = 92.8 bits (229), Expect = 7e-19
Identities = 53/128 (41%), Positives = 73/128 (57%)
Frame = +2
Query: 176 HYRIFDPVMSVVNVEDANRSTRLLAQTTLRYVLGTVDLYSLFTDREDIAASMQETLDMAT 355
+YR DP+ S+ V DA+ STR LAQ++LR VLGT L L TDR IA ++ LD AT
Sbjct: 108 YYRTSDPIASLARVNDAHMSTRQLAQSSLRNVLGTRSLAELMTDRHGIAVQVKYILDSAT 167
Query: 356 DAWGMKVERVEVKDVRIPMQLQXXXXXXXXXXXXXXXXVIAAEGEQKSSKAFKNSCRKRL 535
WG+ VERVE+KD+R+P ++ V+ A+GE +S AF+ + L
Sbjct: 168 LFWGIHVERVEIKDIRLpreMCRAMAAEAEAQRESDAKVVTAQGELDASMAFQKAA-DEL 226
Query: 536 YKCPISLQ 559
P +LQ
Sbjct: 227 AGSPTALQ 234
Score = 48.1 bits (113), Expect = 2e-05
Identities = 19/34 (55%), Positives = 28/34 (82%)
Frame = +3
Query: 42 GAGLIFILPCLDSMKRIDLRTLTFDVPTQEVLTR 143
G G++ +LP +DS K +DLR +++DVPTQE+LTR
Sbjct: 63 GPGIVLVLPFIDSHKTVDLRVMSYDVPTQEMLTR 96
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,450,211
Number of Sequences: 369166
Number of extensions: 984768
Number of successful extensions: 2353
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2305
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2345
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5413810770
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)