Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_I13
(518 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q62433|NDRG1_MOUSE NDRG1 protein (N-myc downstream regul... 45 1e-04
sp|Q92597|NDRG1_HUMAN NDRG1 protein (N-myc downstream regul... 42 9e-04
sp|Q9UN36|NDRG2_HUMAN NDRG2 protein (Syld709613 protein) 41 0.002
sp|Q9Z2L9|NDRG4_RAT NDRG4 protein (Brain development-relate... 40 0.004
sp|Q9QYG0|NDRG2_MOUSE NDRG2 protein (Ndr2 protein) 40 0.004
sp|Q9ULP0|NDRG4_HUMAN NDRG4 protein (Brain development-rela... 39 0.006
sp|Q8BTG7|NDRG4_MOUSE NDRG4 protein 38 0.013
sp|Q9UGV2|NDRG3_HUMAN NDRG3 protein 30 2.6
sp|Q10302|YD49_SCHPO Hypothetical protein C22H10.09 in chro... 29 5.9
sp|Q72DV1|SSRP_DESVH SsrA-binding protein 29 5.9
>sp|Q62433|NDRG1_MOUSE NDRG1 protein (N-myc downstream regulated gene 1 protein) (Protein
Ndr1)
Length = 394
Score = 45.1 bits (105), Expect = 1e-04
Identities = 36/150 (24%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Frame = +1
Query: 10 NTKNLHGYVTSYMNRSNL-IDKSM------SIRCPMLFISGSLANYADDVKCLYEDIQGF 168
N NLH ++++Y +R +L I++ M +++CP L + G + D V ++
Sbjct: 220 NPSNLHLFISAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDNSPAVDAV------VECN 273
Query: 169 LKNDPDRKRHIEFMEIDNCANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMSSTVRPTG 348
K DP + ++ + + + ++AE+ +YF+QG G + SA R+ + +G
Sbjct: 274 SKLDPTKTTLLKMADCGGLPQI--SQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASG 331
Query: 349 NRKISMEEYDSPKGPSNITYNPRRKYSESE 438
+ S+E + S+ + PR + SE
Sbjct: 332 SSVTSLE---GTRSRSHTSEGPRSRSHTSE 358
>sp|Q92597|NDRG1_HUMAN NDRG1 protein (N-myc downstream regulated gene 1 protein)
(Differentiation-related gene 1 protein) (DRG1)
(Reducing agents and tunicamycin-responsive protein)
(RTP) (Nickel-specific induction protein Cap43) (Rit42)
Length = 394
Score = 42.0 bits (97), Expect = 9e-04
Identities = 35/150 (23%), Positives = 70/150 (46%), Gaps = 7/150 (4%)
Frame = +1
Query: 10 NTKNLHGYVTSYMNRSNL-IDKSM------SIRCPMLFISGSLANYADDVKCLYEDIQGF 168
N NLH ++ +Y +R +L I++ M +++CP L + G + D V ++
Sbjct: 220 NPGNLHLFINAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDSSPAVDAV------VECN 273
Query: 169 LKNDPDRKRHIEFMEIDNCANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMSSTVRPTG 348
K DP + ++ + + + ++AE+ +YF+QG G + SA R+ + +G
Sbjct: 274 SKLDPTKTTLLKMADCGGLPQI--SQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASG 331
Query: 349 NRKISMEEYDSPKGPSNITYNPRRKYSESE 438
+ S+ D + S+ + R + SE
Sbjct: 332 S---SVTSLDGTRSRSHTSEGTRSRSHTSE 358
>sp|Q9UN36|NDRG2_HUMAN NDRG2 protein (Syld709613 protein)
Length = 371
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/109 (26%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Frame = +1
Query: 10 NTKNLHGYVTSYMNRSNLIDK---SMSIRCPMLFISGSLANYADDVKCLYEDIQGFLKND 180
N N+ Y SY NR +L + +++RCP++ + G A + D V ++ K D
Sbjct: 226 NLDNIELYWNSYNNRRDLNFERGGDITLRCPVMLVVGDQAPHEDAV------VECNSKLD 279
Query: 181 PDRKRHIEFMEIDNCANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMS 327
P + ++ D+ + + ++ E+ +YFLQG G + S+ R+S
Sbjct: 280 PTQTSFLKMA--DSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLS 326
>sp|Q9Z2L9|NDRG4_RAT NDRG4 protein (Brain development-related molecule 1)
Length = 352
Score = 39.7 bits (91), Expect = 0.004
Identities = 24/102 (23%), Positives = 46/102 (45%)
Frame = +1
Query: 46 MNRSNLIDKSMSIRCPMLFISGSLANYADDVKCLYEDIQGFLKNDPDRKRHIEFMEIDNC 225
+NR + + ++RCP++ + G A D V ++ K DP ++ +
Sbjct: 213 INRPGTVPNAKTLRCPVMLVVGDNAPAEDGV------VECNSKLDPTTTTFLKMADSGGL 266
Query: 226 ANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMSSTVRPTGN 351
V + ++ E+ +YFLQG G + RR+S P+ +
Sbjct: 267 PQVT--QPGKLTEAFKYFLQGMGYIAHLKDRRLSGGAVPSAS 306
>sp|Q9QYG0|NDRG2_MOUSE NDRG2 protein (Ndr2 protein)
Length = 371
Score = 39.7 bits (91), Expect = 0.004
Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Frame = +1
Query: 10 NTKNLHGYVTSYMNRSNLIDK---SMSIRCPMLFISGSLANYADDVKCLYEDIQGFLKND 180
N +N+ Y SY NR +L + +++CP++ + G A + D V ++ K D
Sbjct: 226 NLENIELYWNSYNNRRDLNFERGGETTLKCPVMLVVGDQAPHEDAV------VECNSKLD 279
Query: 181 PDRKRHIEFMEIDNCANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMS 327
P + ++ D+ + + ++ E+ +YFLQG G + S+ R+S
Sbjct: 280 PTQTSFLKMA--DSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLS 326
>sp|Q9ULP0|NDRG4_HUMAN NDRG4 protein (Brain development-related molecule 1) (Vascular
smooth muscle cell associated protein 8) (SMAP-8)
Length = 352
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/102 (23%), Positives = 46/102 (45%)
Frame = +1
Query: 46 MNRSNLIDKSMSIRCPMLFISGSLANYADDVKCLYEDIQGFLKNDPDRKRHIEFMEIDNC 225
+NR + + ++RCP++ + G A D V ++ K DP ++ +
Sbjct: 213 INRPGTVPNAKTLRCPVMLVVGDNAPAEDGV------VECNSKLDPTTTTFLKMADSGGL 266
Query: 226 ANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMSSTVRPTGN 351
V + ++ E+ +YFLQG G + RR+S P+ +
Sbjct: 267 PQVT--QPGKLTEAFKYFLQGMGYIAYLKDRRLSGGAVPSAS 306
>sp|Q8BTG7|NDRG4_MOUSE NDRG4 protein
Length = 352
Score = 38.1 bits (87), Expect = 0.013
Identities = 23/102 (22%), Positives = 46/102 (45%)
Frame = +1
Query: 46 MNRSNLIDKSMSIRCPMLFISGSLANYADDVKCLYEDIQGFLKNDPDRKRHIEFMEIDNC 225
+NR + + ++RCP++ + G A + V ++ K DP ++ +
Sbjct: 213 INRPGTVPNAKTLRCPVMLVVGDNAPAEEGV------VECNSKLDPTTTTFLKMADSGGL 266
Query: 226 ANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMSSTVRPTGN 351
V + ++ E+ +YFLQG G + RR+S P+ +
Sbjct: 267 PQVT--QPGKLTEAFKYFLQGMGYIAHLKDRRLSGGAVPSAS 306
>sp|Q9UGV2|NDRG3_HUMAN NDRG3 protein
Length = 375
Score = 30.4 bits (67), Expect = 2.6
Identities = 25/116 (21%), Positives = 51/116 (43%), Gaps = 10/116 (8%)
Frame = +1
Query: 10 NTKNLHGYVTSYMNRSNLI----------DKSMSIRCPMLFISGSLANYADDVKCLYEDI 159
N NL ++ SY R +L +KS +++C L + G D+ + +
Sbjct: 218 NQDNLQLFLNSYNGRRDLEIERPILGQNDNKSKTLKCSTLLVVG------DNSPAVEAVV 271
Query: 160 QGFLKNDPDRKRHIEFMEIDNCANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMS 327
+ + +P ++ + V+ + ++ E+ +YFLQG G + SA R++
Sbjct: 272 ECNSRLNPINTTLLKMADCGGLPQVV--QPGKLTEAFKYFLQGMGYIPSASMTRLA 325
>sp|Q10302|YD49_SCHPO Hypothetical protein C22H10.09 in chromosome I
Length = 646
Score = 29.3 bits (64), Expect = 5.9
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Frame = +1
Query: 19 NLHGYVTSYMNRSNLIDKSMSIRCPMLFISGSLANYADDVKCLYEDIQGFLKNDPDRKRH 198
NL+ + + N SN D S +LF + Y+D+ K L + L+ DPD +R
Sbjct: 110 NLYYQLLMFTNYSNPKDNGFS---KLLF-----SQYSDEKKVLVNFVYNVLRLDPDLQRQ 161
Query: 199 IEFME------IDNCANVI-VERTDQVAESLQYFLQ 285
+E ++ C + + + RTD + SL+ LQ
Sbjct: 162 KRILESIISAALNICVSTVNLSRTD-LKSSLKIILQ 196
>sp|Q72DV1|SSRP_DESVH SsrA-binding protein
Length = 154
Score = 29.3 bits (64), Expect = 5.9
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Frame = +1
Query: 154 DIQGFLKNDPDRKRHI--EFMEIDNCANVIVERTDQVAESLQYFLQGQGLVGSAPSR 318
D G+ ++DPDR R + EI+N A + ++ V + YF +G+ V A R
Sbjct: 71 DNAGYAQHDPDRDRKLLLHAHEIENLARSVEQKGYTVVPTKLYFARGKVKVDIAVGR 127
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,729,722
Number of Sequences: 369166
Number of extensions: 1031186
Number of successful extensions: 2350
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2315
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2347
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3403581975
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)