Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_H01
(403 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P48375|FKB12_DROME 12 kDa FK506-binding protein (FKBP) (... 159 1e-39
sp|O42123|FKB1A_XENLA FK506-binding protein 1A (Peptidyl-pr... 148 4e-36
sp|P68106|FKB1B_HUMAN FK506-binding protein 1B (Peptidyl-pr... 148 4e-36
sp|P18203|FKB1A_BOVIN FK506-binding protein 1A (Peptidyl-pr... 147 6e-36
sp|Q9Z2I2|FKB1B_MOUSE FK506-binding protein 1B (Peptidyl-pr... 147 1e-35
sp|P62943|FKB1A_RABIT FK506-binding protein 1A (Peptidyl-pr... 145 2e-35
sp|P97534|FKB1B_RAT FK506-binding protein 1B (Peptidyl-prol... 145 2e-35
sp|P26883|FKB1A_MOUSE FK506-binding protein 1A (Peptidyl-pr... 140 9e-34
sp|Q62658|FKB1A_RAT FK506-binding protein 1A (Peptidyl-prol... 140 9e-34
sp|O42993|FKBP_SCHPO FK506-binding protein (FKBP) (Peptidyl... 129 3e-30
>sp|P48375|FKB12_DROME 12 kDa FK506-binding protein (FKBP) (Peptidyl-prolyl cis-trans
isomerase) (PPIase) (Rotamase) (Macrolide-binding
protein)
Length = 108
Score = 159 bits (403), Expect = 1e-39
Identities = 74/101 (73%), Positives = 84/101 (83%)
Frame = +3
Query: 6 IKPGDECTYPKKGQTVEVHYTGTLTNGNKFDSSRDRNRPLKFKLGYGEVIRGWDEGVAQL 185
I PGD TYPK GQ V VHYTGTL +G KFDSSRDRN+P KF +G GEVIRGWDEGVAQL
Sbjct: 8 IAPGDGSTYPKNGQKVTVHYTGTLDDGTKFDSSRDRNKPFKFTIGKGEVIRGWDEGVAQL 67
Query: 186 SLGERAKLTCSPDFAYGSQGIEGVIPPNSVLIFDVELISIK 308
S+G+RAKL CSPD+AYGS+G GVIPPNS L FDVEL+ ++
Sbjct: 68 SVGQRAKLICSPDYAYGSRGHPGVIPPNSTLTFDVELLKVE 108
>sp|O42123|FKB1A_XENLA FK506-binding protein 1A (Peptidyl-prolyl cis-trans isomerase)
(PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12)
(Immunophilin FKBP12)
Length = 108
Score = 148 bits (373), Expect = 4e-36
Identities = 68/101 (67%), Positives = 83/101 (82%)
Frame = +3
Query: 6 IKPGDECTYPKKGQTVEVHYTGTLTNGNKFDSSRDRNRPLKFKLGYGEVIRGWDEGVAQL 185
I GD T+PKKGQTV VHY G+L NG KFDSSRDRN+P KF +G EVIRGW+EGVAQ+
Sbjct: 8 ITEGDGRTFPKKGQTVVVHYVGSLENGKKFDSSRDRNKPFKFIIGRCEVIRGWEEGVAQM 67
Query: 186 SLGERAKLTCSPDFAYGSQGIEGVIPPNSVLIFDVELISIK 308
S+G+RA+LTCSPDFAYG+ G G+IPPN+ L FDVEL+ ++
Sbjct: 68 SVGQRARLTCSPDFAYGATGHPGIIPPNATLTFDVELLRLE 108
>sp|P68106|FKB1B_HUMAN FK506-binding protein 1B (Peptidyl-prolyl cis-trans isomerase 1B)
(PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6)
(Immunophilin FKBP12.6) (h-FKBP-12)
sp|P68107|FKB1B_BOVIN FK506-binding protein 1B (Peptidyl-prolyl cis-trans isomerase 1B)
(PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6)
(Immunophilin FKBP12.6)
Length = 108
Score = 148 bits (373), Expect = 4e-36
Identities = 68/101 (67%), Positives = 84/101 (83%)
Frame = +3
Query: 6 IKPGDECTYPKKGQTVEVHYTGTLTNGNKFDSSRDRNRPLKFKLGYGEVIRGWDEGVAQL 185
I PGD T+PKKGQT VHYTG L NG KFDSSRDRN+P KF++G EVI+G++EG AQ+
Sbjct: 8 ISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQM 67
Query: 186 SLGERAKLTCSPDFAYGSQGIEGVIPPNSVLIFDVELISIK 308
SLG+RAKLTC+PD AYG+ G GVIPPN+ LIFDVEL++++
Sbjct: 68 SLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 108
>sp|P18203|FKB1A_BOVIN FK506-binding protein 1A (Peptidyl-prolyl cis-trans isomerase)
(PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12)
(Immunophilin FKBP12)
Length = 108
Score = 147 bits (372), Expect = 6e-36
Identities = 68/101 (67%), Positives = 83/101 (82%)
Frame = +3
Query: 6 IKPGDECTYPKKGQTVEVHYTGTLTNGNKFDSSRDRNRPLKFKLGYGEVIRGWDEGVAQL 185
I PGD T+PK+GQT VHYTG L +G KFDSSRDRN+P KF LG EVIRGW+EGVAQ+
Sbjct: 8 ISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFVLGKQEVIRGWEEGVAQM 67
Query: 186 SLGERAKLTCSPDFAYGSQGIEGVIPPNSVLIFDVELISIK 308
S+G+RAKLT SPD+AYG+ G G+IPPN+ LIFDVEL+ ++
Sbjct: 68 SVGQRAKLTISPDYAYGATGHPGIIPPNATLIFDVELLKLE 108
>sp|Q9Z2I2|FKB1B_MOUSE FK506-binding protein 1B (Peptidyl-prolyl cis-trans isomerase 1B)
(PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6)
(Immunophilin FKBP12.6)
Length = 108
Score = 147 bits (370), Expect = 1e-35
Identities = 68/101 (67%), Positives = 83/101 (82%)
Frame = +3
Query: 6 IKPGDECTYPKKGQTVEVHYTGTLTNGNKFDSSRDRNRPLKFKLGYGEVIRGWDEGVAQL 185
I PGD T+PKKGQ VHYTG L NG KFDSSRDRN+P KF++G EVI+G++EG AQ+
Sbjct: 8 ISPGDGRTFPKKGQICVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGTAQM 67
Query: 186 SLGERAKLTCSPDFAYGSQGIEGVIPPNSVLIFDVELISIK 308
SLG+RAKLTC+PD AYG+ G GVIPPN+ LIFDVEL+S++
Sbjct: 68 SLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLSLE 108
>sp|P62943|FKB1A_RABIT FK506-binding protein 1A (Peptidyl-prolyl cis-trans isomerase)
(PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12)
(Immunophilin FKBP12)
sp|P62942|FKB1A_HUMAN FK506-binding protein 1A (Peptidyl-prolyl cis-trans isomerase)
(PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12)
(Immunophilin FKBP12)
Length = 108
Score = 145 bits (367), Expect = 2e-35
Identities = 66/101 (65%), Positives = 83/101 (82%)
Frame = +3
Query: 6 IKPGDECTYPKKGQTVEVHYTGTLTNGNKFDSSRDRNRPLKFKLGYGEVIRGWDEGVAQL 185
I PGD T+PK+GQT VHYTG L +G KFDSSRDRN+P KF LG EVIRGW+EGVAQ+
Sbjct: 8 ISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQM 67
Query: 186 SLGERAKLTCSPDFAYGSQGIEGVIPPNSVLIFDVELISIK 308
S+G+RAKLT SPD+AYG+ G G+IPP++ L+FDVEL+ ++
Sbjct: 68 SVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE 108
>sp|P97534|FKB1B_RAT FK506-binding protein 1B (Peptidyl-prolyl cis-trans isomerase 1B)
(PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6)
(Immunophilin FKBP12.6)
Length = 108
Score = 145 bits (367), Expect = 2e-35
Identities = 67/101 (66%), Positives = 83/101 (82%)
Frame = +3
Query: 6 IKPGDECTYPKKGQTVEVHYTGTLTNGNKFDSSRDRNRPLKFKLGYGEVIRGWDEGVAQL 185
I PGD T+PKKGQ VHYTG L NG KFDSSRDRN+P KF++G EVI+G++EG AQ+
Sbjct: 8 ISPGDGRTFPKKGQICVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQM 67
Query: 186 SLGERAKLTCSPDFAYGSQGIEGVIPPNSVLIFDVELISIK 308
SLG+RAKLTC+PD AYG+ G GVIPPN+ LIFDVEL++++
Sbjct: 68 SLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 108
>sp|P26883|FKB1A_MOUSE FK506-binding protein 1A (Peptidyl-prolyl cis-trans isomerase)
(PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12)
(Immunophilin FKBP12)
Length = 108
Score = 140 bits (353), Expect = 9e-34
Identities = 64/101 (63%), Positives = 81/101 (80%)
Frame = +3
Query: 6 IKPGDECTYPKKGQTVEVHYTGTLTNGNKFDSSRDRNRPLKFKLGYGEVIRGWDEGVAQL 185
I PGD T+PK+GQT VHYTG L +G KFDSSRDRN+P KF LG EVIRGW+EGVAQ+
Sbjct: 8 ISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFTLGKQEVIRGWEEGVAQM 67
Query: 186 SLGERAKLTCSPDFAYGSQGIEGVIPPNSVLIFDVELISIK 308
S+G+RAKL S D+AYG+ G G+IPP++ L+FDVEL+ ++
Sbjct: 68 SVGQRAKLIISSDYAYGATGHPGIIPPHATLVFDVELLKLE 108
>sp|Q62658|FKB1A_RAT FK506-binding protein 1A (Peptidyl-prolyl cis-trans isomerase)
(PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12)
(Immunophilin FKBP12)
Length = 108
Score = 140 bits (353), Expect = 9e-34
Identities = 64/101 (63%), Positives = 81/101 (80%)
Frame = +3
Query: 6 IKPGDECTYPKKGQTVEVHYTGTLTNGNKFDSSRDRNRPLKFKLGYGEVIRGWDEGVAQL 185
I GD T+PK+GQT VHYTG L +G KFDSSRDRN+P KF LG EVIRGW+EGVAQ+
Sbjct: 8 ISSGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFTLGKQEVIRGWEEGVAQM 67
Query: 186 SLGERAKLTCSPDFAYGSQGIEGVIPPNSVLIFDVELISIK 308
S+G+RAKL SPD+AYG+ G G+IPP++ L+FDVEL+ ++
Sbjct: 68 SVGQRAKLIISPDYAYGATGHPGIIPPHATLVFDVELLKLE 108
>sp|O42993|FKBP_SCHPO FK506-binding protein (FKBP) (Peptidyl-prolyl cis-trans isomerase)
(PPIase)
Length = 112
Score = 129 bits (323), Expect = 3e-30
Identities = 58/100 (58%), Positives = 75/100 (75%)
Frame = +3
Query: 6 IKPGDECTYPKKGQTVEVHYTGTLTNGNKFDSSRDRNRPLKFKLGYGEVIRGWDEGVAQL 185
I G+ +PK G + +HYTGTLTNG KFDSS DR P +G G++IRGWDEGV ++
Sbjct: 8 ISSGNGQDFPKPGDRITMHYTGTLTNGKKFDSSVDRGSPFVCTIGVGQLIRGWDEGVPKM 67
Query: 186 SLGERAKLTCSPDFAYGSQGIEGVIPPNSVLIFDVELISI 305
SLGE+AKLT +PD+ YG +G G+IPPNS L+FDVEL++I
Sbjct: 68 SLGEKAKLTITPDYGYGPRGFPGLIPPNSTLLFDVELLAI 107
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,293,704
Number of Sequences: 369166
Number of extensions: 812074
Number of successful extensions: 1865
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1728
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1799
length of database: 68,354,980
effective HSP length: 98
effective length of database: 50,250,950
effective search space used: 1758783250
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)