Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_G05
(809 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q25464|FP2_MYTGA Adhesive plaque matrix protein 2 precur... 65 2e-10
sp|P07207|NOTCH_DROME Neurogenic locus Notch protein precursor 62 2e-09
sp|P13508|GLP1_CAEEL Glp-1 protein precursor 59 1e-08
sp|P46530|NOTC1_BRARE Neurogenic locus notch homolog protei... 59 2e-08
sp|P24014|SLIT_DROME Slit protein precursor [Contains: Slit... 58 3e-08
sp|P21783|NOTCH_XENLA Neurogenic locus notch protein homolo... 58 3e-08
sp|Q63722|JAG1_RAT Jagged-1 precursor (Jagged1) 55 2e-07
sp|Q9QXX0|JAG1_MOUSE Jagged-1 precursor (Jagged1) 55 3e-07
sp|P49013|FBP3_STRPU Fibropellin C precursor (Epidermal gro... 55 3e-07
sp|P14585|LIN12_CAEEL Lin-12 protein precursor 54 4e-07
>sp|Q25464|FP2_MYTGA Adhesive plaque matrix protein 2 precursor (Foot protein 2) (MGFP2)
(MGFP-2)
Length = 473
Score = 65.1 bits (157), Expect = 2e-10
Identities = 41/126 (32%), Positives = 56/126 (44%), Gaps = 1/126 (0%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREGLY-YNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECK 194
C P Y C C+ G Y YN LKN C + QC+N C+ G T++C
Sbjct: 60 CKPRGGSYKC------FCKGGYYGYNCN----LKNACKPN--QCKNKSRCVPVGKTFKCV 107
Query: 195 CLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPCIC 374
C + G+LCEK GKC G Y C+CS G+TG +C++ +P C
Sbjct: 108 CRNGNFGRLCEK-NVCSPNPCKNNGKC--SPLGKTGYKCTCSGGYTGPRCEVHACKPNPC 164
Query: 375 PKNMKC 392
+C
Sbjct: 165 KNKGRC 170
Score = 58.2 bits (139), Expect = 3e-08
Identities = 40/131 (30%), Positives = 57/131 (43%), Gaps = 3/131 (2%)
Frame = +3
Query: 42 SCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKL 221
S DG G CR Y+ C N C + C+N+G C+N G +Y C C Y G
Sbjct: 245 SSDGSGGYRCRCKGGYSGPT--CKVNVCKPT--PCKNSGRCVNKGSSYNCICKGGYSGPT 300
Query: 222 CEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPC---ICPKNMKC 392
C + G+C+ N D + C C G+ G C+ + PC C KC
Sbjct: 301 CGE-NVCKPNPCQNRGRCYPDNSDDG-FKCRCVGGYKGPTCEDK-PNPCNTKPCKNGGKC 357
Query: 393 NYSESGALFSC 425
NY +G +++C
Sbjct: 358 NY--NGKIYTC 366
Score = 56.6 bits (135), Expect = 8e-08
Identities = 39/129 (30%), Positives = 55/129 (42%), Gaps = 6/129 (4%)
Frame = +3
Query: 24 PIENEYSCDGFG---NKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCI--NNGLTYE 188
P +N C G N IC+ G C +N C + CQN G C N+ ++
Sbjct: 274 PCKNSGRCVNKGSSYNCICKGGY----SGPTCGENVCKPN--PCQNRGRCYPDNSDDGFK 327
Query: 189 CKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQP 365
C+C+ Y G CE K GKC N+ K+Y C C+ G+ G C + Y+P
Sbjct: 328 CRCVGGYKGPTCEDKPNPCNTKPCKNGGKC---NYNGKIYTCKCAYGWRGRHCTDKAYKP 384
Query: 366 CICPKNMKC 392
C + C
Sbjct: 385 NPCVVSKPC 393
Score = 55.1 bits (131), Expect = 2e-07
Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Frame = +3
Query: 144 CQNNGYCINNGLT-YECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 320
C+N G C +G T Y+C+C+D Y G C++ G C GD Y+C C
Sbjct: 164 CKNKGRCFPDGKTGYKCRCVDGYSGPTCQENACKPNPCSNG-GTCSADKFGD--YSCECR 220
Query: 321 EGFTGEKCDLRIYQPCICPKNMKCNYSESG 410
G+ G +C+ + P C C+ SG
Sbjct: 221 PGYFGPECERYVCAPNPCKNGGICSSDGSG 250
Score = 53.9 bits (128), Expect = 5e-07
Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +3
Query: 117 NNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCE----KXXXXXXXXXXXXGKCFVQ 284
N C+ S C+N G CI NG Y CKC Y G+ C K GKC +
Sbjct: 385 NPCVVSK-PCKNRGKCIWNGKAYRCKCAYGYGGRHCTKKSYKKNPCASRPCKNRGKCTDK 443
Query: 285 NHGDKLYACSCSEGFTGEKCDLR 353
+G Y C C+ G++G C L+
Sbjct: 444 GNG---YVCKCARGYSGRYCSLK 463
Score = 44.7 bits (104), Expect = 3e-04
Identities = 25/93 (26%), Positives = 34/93 (36%)
Frame = +3
Query: 117 NNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGD 296
N C+ C+ NG C G +Y+C C Y G C +C
Sbjct: 47 NPCLKK--PCKYNGVCKPRGGSYKCFCKGGYYGYNCNLKNACKPNQCKNKSRCVPVG--- 101
Query: 297 KLYACSCSEGFTGEKCDLRIYQPCICPKNMKCN 395
K + C C G G C+ + P C N KC+
Sbjct: 102 KTFKCVCRNGNFGRLCEKNVCSPNPCKNNGKCS 134
>sp|P07207|NOTCH_DROME Neurogenic locus Notch protein precursor
Length = 2703
Score = 61.6 bits (148), Expect = 2e-09
Identities = 48/181 (26%), Positives = 71/181 (39%), Gaps = 5/181 (2%)
Frame = +3
Query: 24 PIENEYSC-DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCL 200
P NE C DG IC Y + + + C S+ CQ+ G C + + C+C+
Sbjct: 761 PCVNEGRCEDGINEFICHCPPGYTGKRCELDIDECSSN--PCQHGGTCYDKLNAFSCQCM 818
Query: 201 DSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPCI-- 371
Y G+ CE G C + +G Y C C FTG C+ ++ PC
Sbjct: 819 PGYTGQKCETNIDDCVTNPCGNGGTCIDKVNG---YKCVCKVPFTGRDCESKM-DPCASN 874
Query: 372 -CPKNMKCNYSESGALFSCTSENEADSSNPKSDYSNRKVKQNWKDVSLSTTIVAAVGCMT 548
C KC S + FSCT K Y+ R ++ + SLS+ C+
Sbjct: 875 RCKNEAKCTPSSNFLDFSCTC---------KLGYTGRYCDEDIDECSLSSPCRNGASCLN 925
Query: 549 I 551
+
Sbjct: 926 V 926
Score = 55.1 bits (131), Expect = 2e-07
Identities = 34/109 (31%), Positives = 42/109 (38%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKC 197
C Y C +C G Y ++ C S CQN G C +NGL+YECKC
Sbjct: 232 CVNTHGSYQC------MCPTG--YTGKDCDTKYKPCSPS--PCQNGGICRSNGLSYECKC 281
Query: 198 LDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKC 344
+ GK CE+ G + D Y C C FTG C
Sbjct: 282 PKGFEGKNCEQNYDDCLGHLCQNGGTCIDGISD--YTCRCPPNFTGRFC 328
Score = 49.7 bits (117), Expect = 1e-05
Identities = 32/109 (29%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Frame = +3
Query: 24 PIENEYSCDGFGNKI-CREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCL 200
P +N +C + N C L ++ + +C S+ C N G CI+ Y C CL
Sbjct: 992 PCQNGATCSQYVNSYTCTCPLGFSGINCQTNDEDCTESS--CLNGGSCIDGINGYNCSCL 1049
Query: 201 DSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKC 344
Y G C+ K C QN+ Y C C GFTG++C
Sbjct: 1050 AGYSGANCQYKLNKCDSNPCLNGATCHEQNNE---YTCHCPSGFTGKQC 1095
Score = 49.7 bits (117), Expect = 1e-05
Identities = 35/120 (29%), Positives = 44/120 (36%)
Frame = +3
Query: 9 TTFCFPIENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
T C + N Y C+ CR G E K + C S CQN G C +
Sbjct: 1311 TLDCVQLVNNYHCN------CRPGHMGRHCEHKV--DFCAQS--PCQNGGNCNIRQSGHH 1360
Query: 189 CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPC 368
C C + + GK CE G C V + G Y C C G GE C++ C
Sbjct: 1361 CICNNGFYGKNCELSGQDCDSNPCRVGNCVVADEGFG-YRCECPRGTLGEHCEIDTLDEC 1419
Score = 48.5 bits (114), Expect = 2e-05
Identities = 30/109 (27%), Positives = 43/109 (39%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKC 197
C + Y C +C +G Y ++ ++C S CQN G C++ Y C C
Sbjct: 923 CLNVPGSYRC------LCTKG--YEGRDCAINTDDCAS--FPCQNGGTCLDGIGDYSCLC 972
Query: 198 LDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKC 344
+D + GK CE G Q Y C+C GF+G C
Sbjct: 973 VDGFDGKHCETDINECLSQPCQNGATCSQYVNS--YTCTCPLGFSGINC 1019
Score = 47.8 bits (112), Expect = 4e-05
Identities = 38/144 (26%), Positives = 53/144 (36%), Gaps = 10/144 (6%)
Frame = +3
Query: 24 PIENEYSCD---GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECK 194
PI Y+C G+ C E + Q S C ++NG C+N +Y C
Sbjct: 428 PINGSYACSCATGYKGVDCSEDIDECDQGSPC------------EHNGICVNTPGSYRCN 475
Query: 195 CLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKL-----YACSCSEGFTGEKCDLRI- 356
C + G CE QN G L + C C GFTG +C++ I
Sbjct: 476 CSQGFTGPRCETNINECESHP-------CQNEGSCLDDPGTFRCVCMPGFTGTQCEIDID 528
Query: 357 -YQPCICPKNMKCNYSESGALFSC 425
Q C + C+ +G SC
Sbjct: 529 ECQSNPCLNDGTCHDKINGFKCSC 552
Score = 46.2 bits (108), Expect = 1e-04
Identities = 37/142 (26%), Positives = 53/142 (37%), Gaps = 6/142 (4%)
Frame = +3
Query: 18 CFPIENEYSC---DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C N + C G+ IC++ + N C S+ CQ +G+C + +Y
Sbjct: 616 CIDDVNSFKCLCDPGYTGYICQKQI-----------NECESN--PCQFDGHCQDRVGSYY 662
Query: 189 CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPC 368
C+C GK CE G + G Y C C GFTG+ C+ + C
Sbjct: 663 CQCQAGTSGKNCEVNVNECHSNPCNNGATCID--GINSYKCQCVPGFTGQHCEKNV-DEC 719
Query: 369 I---CPKNMKCNYSESGALFSC 425
I C N C +G C
Sbjct: 720 ISSPCANNGVCIDQVNGYKCEC 741
Score = 46.2 bits (108), Expect = 1e-04
Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 3/116 (2%)
Frame = +3
Query: 18 CFPIENEYSCD---GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C +++++SC G+ K+C + + Q++ K + Q NNG C + G ++
Sbjct: 1113 CSQMKHQFSCKCSAGWTGKLC-DVQTISCQDAADRKGLSLR---QLCNNGTCKDYGNSHV 1168
Query: 189 CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRI 356
C C Y G C+K G G Y C C +GF G+ C+L I
Sbjct: 1169 CYCSQGYAGSYCQKEIDECQSQPCQNGGTCRDLIG--AYECQCRQGFQGQNCELNI 1222
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 3/82 (3%)
Frame = +3
Query: 132 SNIQCQNNGYCIN--NGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQ-NHGDKL 302
+++ CQN G C+ NG TY C C Y+G CE G C V +G
Sbjct: 63 TSVGCQNGGTCVTQLNGKTY-CACDSHYVGDYCEHRNPCNSMRCQNGGTCQVTFRNGRPG 121
Query: 303 YACSCSEGFTGEKCDLRIYQPC 368
+C C GF C++ + C
Sbjct: 122 ISCKCPLGFDESLCEIAVPNAC 143
Score = 45.1 bits (105), Expect = 2e-04
Identities = 34/123 (27%), Positives = 49/123 (39%), Gaps = 6/123 (4%)
Frame = +3
Query: 18 CFPIEN--EYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYEC 191
C P N ++SC K+ G Y + +C S + C+N C+N +Y C
Sbjct: 882 CTPSSNFLDFSCTC---KLGYTGRYCDEDIDEC------SLSSPCRNGASCLNVPGSYRC 932
Query: 192 KCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRI----Y 359
C Y G+ C G + GD Y+C C +GF G+ C+ I
Sbjct: 933 LCTKGYEGRDCAINTDDCASFPCQNGGTCLDGIGD--YSCLCVDGFDGKHCETDINECLS 990
Query: 360 QPC 368
QPC
Sbjct: 991 QPC 993
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/131 (26%), Positives = 46/131 (35%), Gaps = 14/131 (10%)
Frame = +3
Query: 18 CFPIENEYSC---DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C NEY+C GF K C E + + Q C+N C +
Sbjct: 1075 CHEQNNEYTCHCPSGFTGKQCSEYVDWCGQSP-------------CENGATCSQMKHQFS 1121
Query: 189 CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQ--NHG-----DKLYACSCSEGFTGEKCD 347
CKC + GKLC+ G Q N+G + C CS+G+ G C
Sbjct: 1122 CKCSAGWTGKLCDVQTISCQDAADRKGLSLRQLCNNGTCKDYGNSHVCYCSQGYAGSYCQ 1181
Query: 348 LRI----YQPC 368
I QPC
Sbjct: 1182 KEIDECQSQPC 1192
Score = 44.3 bits (103), Expect = 4e-04
Identities = 32/104 (30%), Positives = 40/104 (38%), Gaps = 4/104 (3%)
Frame = +3
Query: 99 ESKC---LKNNCISSNIQCQNNGYCINNGLT-YECKCLDSYIGKLCEKXXXXXXXXXXXX 266
ES C + N C ++ C N G C L Y C C + Y G+ CE
Sbjct: 132 ESLCEIAVPNAC--DHVTCLNGGTCQLKTLEEYTCACANGYTGERCETKNLCASSPCRNG 189
Query: 267 GKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPCICPKNMKCNY 398
C G + CSC GFTG+ C I + C N C Y
Sbjct: 190 ATCTALA-GSSSFTCSCPPGFTGDTCSYDIEE---CQSN-PCKY 228
Score = 43.1 bits (100), Expect = 9e-04
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Frame = +3
Query: 144 CQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 320
C+ G C+N +Y+C C Y GK C+ K G C Y C C
Sbjct: 226 CKYGGTCVNTHGSYQCMCPTGYTGKDCDTKYKPCSPSPCQNGGIC---RSNGLSYECKCP 282
Query: 321 EGFTGEKCDLRIYQPCI 371
+GF G+ C+ + Y C+
Sbjct: 283 KGFEGKNCE-QNYDDCL 298
Score = 43.1 bits (100), Expect = 9e-04
Identities = 31/120 (25%), Positives = 46/120 (38%), Gaps = 5/120 (4%)
Frame = +3
Query: 24 PIENEYSC-DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCL 200
P N+ +C D C L + + ++C S C+N G C ++ Y C+C
Sbjct: 534 PCLNDGTCHDKINGFKCSCALGFTGARCQINIDDCQSQ--PCRNRGICHDSIAGYSCECP 591
Query: 201 DSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ----PC 368
Y G CE GKC + + C C G+TG C +I + PC
Sbjct: 592 PGYTGTSCEININDCDSNPCHRGKCIDDVNS---FKCLCDPGYTGYICQKQINECESNPC 648
Score = 43.1 bits (100), Expect = 9e-04
Identities = 30/109 (27%), Positives = 41/109 (37%), Gaps = 2/109 (1%)
Frame = +3
Query: 33 NEYSC-DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSY 209
N SC DG C Y+ + N C S+ C N C Y C C +
Sbjct: 1033 NGGSCIDGINGYNCSCLAGYSGANCQYKLNKCDSN--PCLNGATCHEQNNEYTCHCPSGF 1090
Query: 210 IGKLCEKXXXXXXXXXXXXG-KCFVQNHGDKLYACSCSEGFTGEKCDLR 353
GK C + G C H ++C CS G+TG+ CD++
Sbjct: 1091 TGKQCSEYVDWCGQSPCENGATCSQMKH---QFSCKCSAGWTGKLCDVQ 1136
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 5/113 (4%)
Frame = +3
Query: 48 DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCE 227
D G+ C+ + + + N C S+ C N CI+ +Y+C+C+ + G+ CE
Sbjct: 656 DRVGSYYCQCQAGTSGKNCEVNVNECHSN--PCNNGATCIDGINSYKCQCVPGFTGQHCE 713
Query: 228 K-XXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKC----DLRIYQPCI 371
K G C Q +G Y C C GF C D PC+
Sbjct: 714 KNVDECISSPCANNGVCIDQVNG---YKCECPRGFYDAHCLSDVDECASNPCV 763
Score = 41.6 bits (96), Expect = 0.003
Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 5/110 (4%)
Frame = +3
Query: 114 KNNCISSNIQCQNNGYC---INNGLT-YECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFV 281
+N C ++++CQN G C NG CKC + LCE
Sbjct: 97 RNPC--NSMRCQNGGTCQVTFRNGRPGISCKCPLGFDESLCEIAVPNACDHVTCLNGGTC 154
Query: 282 QNHGDKLYACSCSEGFTGEKCDLR-IYQPCICPKNMKCNYSESGALFSCT 428
Q + Y C+C+ G+TGE+C+ + + C C + F+C+
Sbjct: 155 QLKTLEEYTCACANGYTGERCETKNLCASSPCRNGATCTALAGSSSFTCS 204
Score = 41.6 bits (96), Expect = 0.003
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +3
Query: 117 NNCISSNIQCQNNGY--CINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQN 287
N C+S+ C N G C+ Y C C ++G+ CE K G C ++
Sbjct: 1299 NECLSN--PCSNAGTLDCVQLVNNYHCNCRPGHMGRHCEHKVDFCAQSPCQNGGNCNIRQ 1356
Query: 288 HGDKLYACSCSEGFTGEKCDL 350
G + C C+ GF G+ C+L
Sbjct: 1357 SG---HHCICNNGFYGKNCEL 1374
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 10/103 (9%)
Frame = +3
Query: 66 ICRE-GLYYNAQESKCLKNNCISSNIQ------CQNNGYCINNGLTYECKCLDSYIGKLC 224
ICR GL Y + K + N CQN G CI+ Y C+C ++ G+ C
Sbjct: 269 ICRSNGLSYECKCPKGFEGKNCEQNYDDCLGHLCQNGGTCIDGISDYTCRCPPNFTGRFC 328
Query: 225 E---KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKC 344
+ G HG Y+C C G+ G C
Sbjct: 329 QDDVDECAQRDHPVCQNGATCTNTHGS--YSCICVNGWAGLDC 369
Score = 40.0 bits (92), Expect = 0.008
Identities = 24/98 (24%), Positives = 34/98 (34%), Gaps = 2/98 (2%)
Frame = +3
Query: 144 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 323
C NNG CI+ +EC C ++G CE Y C+C
Sbjct: 1268 CHNNGSCIDRVGGFECVCQPGFVGARCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCRP 1327
Query: 324 GFTGEKCDLRI--YQPCICPKNMKCNYSESGALFSCTS 431
G G C+ ++ C CN +SG C +
Sbjct: 1328 GHMGRHCEHKVDFCAQSPCQNGGNCNIRQSGHHCICNN 1365
Score = 39.7 bits (91), Expect = 0.010
Identities = 35/128 (27%), Positives = 48/128 (37%), Gaps = 8/128 (6%)
Frame = +3
Query: 33 NEYSCDGFGNK---ICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLD 203
N +C +GN C +G S C K + CQN G C + YEC+C
Sbjct: 1156 NNGTCKDYGNSHVCYCSQGY----AGSYCQKEIDECQSQPCQNGGTCRDLIGAYECQCRQ 1211
Query: 204 SYIGKLCE-KXXXXXXXXXXXXGKCF--VQNHGDKLYACSCSEGFTGEKCDLR--IYQPC 368
+ G+ CE G C V N ++CSC G G C++ +P
Sbjct: 1212 GFQGQNCELNIDDCAPNPCQNGGTCHDRVMN-----FSCSCPPGTMGIICEINKDDCKPG 1266
Query: 369 ICPKNMKC 392
C N C
Sbjct: 1267 ACHNNGSC 1274
Score = 36.6 bits (83), Expect = 0.083
Identities = 33/127 (25%), Positives = 45/127 (35%), Gaps = 13/127 (10%)
Frame = +3
Query: 108 CLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQN 287
C N C CI+ ++ C+C G LC C
Sbjct: 369 CSNNTDDCKQAACFYGATCIDGVGSFYCQCTKGKTGLLCHLDDACTSNPCHADAICDTSP 428
Query: 288 HGDKLYACSCSEGFTGEKCDLRIYQ-----PC----IC---PKNMKCNYSESGALFSC-T 428
YACSC+ G+ G C I + PC IC P + +CN S+ C T
Sbjct: 429 INGS-YACSCATGYKGVDCSEDIDECDQGSPCEHNGICVNTPGSYRCNCSQGFTGPRCET 487
Query: 429 SENEADS 449
+ NE +S
Sbjct: 488 NINECES 494
Score = 35.4 bits (80), Expect = 0.19
Identities = 31/120 (25%), Positives = 46/120 (38%), Gaps = 15/120 (12%)
Frame = +3
Query: 36 EYSCDGFGNKICREGLYYNAQES--KCLKNN------CISSNIQCQNN----GYCI--NN 173
E+ D C+ G N ++S C+ NN C S C +N G C+ +
Sbjct: 1335 EHKVDFCAQSPCQNGGNCNIRQSGHHCICNNGFYGKNCELSGQDCDSNPCRVGNCVVADE 1394
Query: 174 GLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDL 350
G Y C+C +G+ CE G GD Y C C + G++CD+
Sbjct: 1395 GFGYRCECPRGTLGEHCEIDTLDECSPNPCAQGAACEDLLGD--YECLCPSKWKGKRCDI 1452
>sp|P13508|GLP1_CAEEL Glp-1 protein precursor
Length = 1295
Score = 59.3 bits (142), Expect = 1e-08
Identities = 37/144 (25%), Positives = 57/144 (39%), Gaps = 7/144 (4%)
Frame = +3
Query: 18 CFPIENEYSC---DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C+P + C +G+G C EG+ + AQ +C C+N+ Y
Sbjct: 131 CYPFYGGFQCICNNGYGGSYCEEGIDHCAQN-------------ECAEGSTCVNSVYNYY 177
Query: 189 CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPC 368
C C G+ CE+ G+C DK + C C G+ GE C+ + C
Sbjct: 178 CDCPIGKSGRYCERTECALMGNICNHGRCIPNRDEDKNFRCVCDSGYEGEFCN-KDKNEC 236
Query: 369 I----CPKNMKCNYSESGALFSCT 428
+ C N C ++ G F+CT
Sbjct: 237 LIEETCVNNSTC-FNLHGD-FTCT 258
Score = 47.4 bits (111), Expect = 5e-05
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Frame = +3
Query: 75 EGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEK-XXXXXXX 251
EG + N +++CL C NN C N + C C Y GK CE+
Sbjct: 225 EGEFCNKDKNECLIEET------CVNNSTCFNLHGDFTCTCKPGYAGKYCEEAIDMCKDY 278
Query: 252 XXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDL 350
G C + +++ C C +GFTG++C++
Sbjct: 279 VCQNDGYC--AHDSNQMPICYCEQGFTGQRCEI 309
Score = 40.0 bits (92), Expect = 0.008
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 3/78 (3%)
Frame = +3
Query: 144 CQNNGYCI---NNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACS 314
C NN CI N+G Y C C + G CE+ G C N + C+
Sbjct: 378 CVNNATCIDLKNSG--YSCHCPLGFYGLNCEQHLLCTPTTCANGGTCEGVNG---VIRCN 432
Query: 315 CSEGFTGEKCDLRIYQPC 368
C GF+G+ C+++ Q C
Sbjct: 433 CPNGFSGDYCEIKDRQLC 450
Score = 38.5 bits (88), Expect = 0.022
Identities = 30/102 (29%), Positives = 37/102 (36%), Gaps = 11/102 (10%)
Frame = +3
Query: 120 NCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCE---KXXXXXXXXXXXXGKCF---- 278
+C SN C N+G CIN C C YIG CE K C
Sbjct: 328 HCSRSNGTCYNDGRCING----FCVCEPDYIGDRCEINRKDFKFPDIQSCKYNPCVNNAT 383
Query: 279 ---VQNHGDKLYACSCSEGFTGEKCDLRIY-QPCICPKNMKC 392
++N G Y+C C GF G C+ + P C C
Sbjct: 384 CIDLKNSG---YSCHCPLGFYGLNCEQHLLCTPTTCANGGTC 422
Score = 33.5 bits (75), Expect = 0.71
Identities = 24/100 (24%), Positives = 38/100 (38%)
Frame = +3
Query: 48 DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCE 227
+G+G C+ L+ + C + C NNG C ++C C + Y G CE
Sbjct: 103 EGYGGPDCKTPLFSGV--NPCDSDPC--------NNGLCYPFYGGFQCICNNGYGGSYCE 152
Query: 228 KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCD 347
+ G V + + Y C C G +G C+
Sbjct: 153 EGIDHCAQNECAEGSTCVNSVYN--YYCDCPIGKSGRYCE 190
Score = 31.6 bits (70), Expect = 2.7
Identities = 26/112 (23%), Positives = 38/112 (33%), Gaps = 2/112 (1%)
Frame = +3
Query: 18 CFPIENE-YSCDGFGNKICREGLY-YNAQESKCLKNNCISSNIQCQNNGYCINNGLTYEC 191
C ++N YSC C G Y N ++ + + + C N G C C
Sbjct: 384 CIDLKNSGYSCH------CPLGFYGLNCEQ------HLLCTPTTCANGGTCEGVNGVIRC 431
Query: 192 KCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCD 347
C + + G CE +N G C C G+TG C+
Sbjct: 432 NCPNGFSGDYCEIKDRQLCSRHPCKNGGVCKNTG----YCECQYGYTGPTCE 479
Score = 31.6 bits (70), Expect = 2.7
Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Frame = +3
Query: 33 NEYSCDGFGNKI---CREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLD 203
N +C+G I C G + E +K+ + S C+N G C N G C+C
Sbjct: 418 NGGTCEGVNGVIRCNCPNGFSGDYCE---IKDRQLCSRHPCKNGGVCKNTGY---CECQY 471
Query: 204 SYIGKLCEK 230
Y G CE+
Sbjct: 472 GYTGPTCEE 480
>sp|P46530|NOTC1_BRARE Neurogenic locus notch homolog protein 1 precursor
Length = 2437
Score = 58.5 bits (140), Expect = 2e-08
Identities = 34/109 (31%), Positives = 46/109 (42%), Gaps = 1/109 (0%)
Frame = +3
Query: 24 PIENEYSCDGF-GNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCL 200
P N C F + IC ++ Q + N C S C+N G CIN +Y C+C
Sbjct: 147 PCANGGQCSAFESHYICTCPPNFHGQTCRQDVNECAVSPSPCRNGGTCINEVGSYLCRCP 206
Query: 201 DSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCD 347
Y G C++ G VQ D + CSC GFTG+ C+
Sbjct: 207 PEYTGPHCQRLYQPCLPSPCRSGGTCVQT-SDTTHTCSCLPGFTGQTCE 254
Score = 55.1 bits (131), Expect = 2e-07
Identities = 37/143 (25%), Positives = 53/143 (37%), Gaps = 6/143 (4%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCI---NNGLTYE 188
C + N++ C+ CR G Y + + + N C + C+N G C N Y
Sbjct: 1282 CVQLINDFRCE------CRTG--YTGKRCETVFNGC--KDTPCKNGGTCAVASNTKHGYI 1331
Query: 189 CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPC 368
CKC Y G CE G V H C C+ GF+G +C R+ PC
Sbjct: 1332 CKCQPGYSGSSCEYDSQSCGSLRCRNGATCVSGHLSP--RCLCAPGFSGHECQTRMDSPC 1389
Query: 369 I---CPKNMKCNYSESGALFSCT 428
+ C C + C+
Sbjct: 1390 LVNPCYNGGTCQPISDAPFYRCS 1412
Score = 53.1 bits (126), Expect = 9e-07
Identities = 36/143 (25%), Positives = 62/143 (43%), Gaps = 13/143 (9%)
Frame = +3
Query: 69 CREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXX 248
CR G ++ + N C S+ C N G CI++ ++C C+ Y G++CE
Sbjct: 777 CRAG--FSGPNCQMNINECASN--PCLNQGSCIDDVAGFKCNCMLPYTGEVCENVLAPCS 832
Query: 249 XXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ----PC----ICPK-----NMK 389
G ++ + ++C+C G+ G+ C++ I + PC +C +
Sbjct: 833 PRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRNPCTNGGVCENLRGGFQCR 892
Query: 390 CNYSESGALFSCTSENEADSSNP 458
CN +GAL EN+ D P
Sbjct: 893 CNPGFTGAL----CENDIDDCEP 911
Score = 50.4 bits (119), Expect = 6e-06
Identities = 38/144 (26%), Positives = 57/144 (39%), Gaps = 10/144 (6%)
Frame = +3
Query: 24 PIENEYSC-DGFGNKIC-----REGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTY 185
P +N+ +C D G C EG++ C C+ NG CI+ ++
Sbjct: 459 PCQNDATCLDQIGGFHCICMPGYEGVFCQINSDDCASQPCL--------NGKCIDKINSF 510
Query: 186 ECKCLDSYIGKLCEKXXXXXXXXXXXXG-KCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ 362
C+C + G LC+ G KC G Y C C+ GF+G C+L I +
Sbjct: 511 HCECPKGFSGSLCQVDVDECASTPCKNGAKC---TDGPNKYTCECTPGFSGIHCELDINE 567
Query: 363 PCICPKNMKCNYS---ESGALFSC 425
P C+Y + A F+C
Sbjct: 568 CASSP----CHYGVCRDGVASFTC 587
Score = 48.9 bits (115), Expect = 2e-05
Identities = 38/151 (25%), Positives = 57/151 (37%), Gaps = 11/151 (7%)
Frame = +3
Query: 39 YSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGK 218
++CD CR G Y + + N C+S C+N G C + Y C C G
Sbjct: 585 FTCD------CRPG--YTGRLCETNINECLSQ--PCRNGGTCQDRENAYICTCPKGTTGV 634
Query: 219 LCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPCICP------- 377
CE GKC + +G Y C C G++G C++ I + P
Sbjct: 635 NCEINIDDCKRKPCDYGKCIDKING---YECVCEPGYSGSMCNINIDDCALNPCHNGGTC 691
Query: 378 ----KNMKCNYSESGALFSCTSENEADSSNP 458
+ C + +C S++ SSNP
Sbjct: 692 IDGVNSFTCLCPDGFRDATCLSQHNECSSNP 722
Score = 47.0 bits (110), Expect = 6e-05
Identities = 36/142 (25%), Positives = 48/142 (33%), Gaps = 6/142 (4%)
Frame = +3
Query: 18 CFPIENEYSC---DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C N Y C G+ +C N C N C N G CI+ ++
Sbjct: 653 CIDKINGYECVCEPGYSGSMC------NINIDDCALN-------PCHNGGTCIDGVNSFT 699
Query: 189 CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPC 368
C C D + C G C Q + Y C C G+ G CD+ I + C
Sbjct: 700 CLCPDGFRDATCLSQHNECSSNPCIHGSCLDQINS---YRCVCEAGWMGRNCDININE-C 755
Query: 369 I---CPKNMKCNYSESGALFSC 425
+ C C SG L +C
Sbjct: 756 LSNPCVNGGTCKDMTSGYLCTC 777
Score = 45.8 bits (107), Expect = 1e-04
Identities = 32/126 (25%), Positives = 51/126 (40%), Gaps = 8/126 (6%)
Frame = +3
Query: 18 CFPIENEYSC---DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C N ++C DGF + C +Q ++C N CI +G C++ +Y
Sbjct: 691 CIDGVNSFTCLCPDGFRDATCL------SQHNECSSNPCI--------HGSCLDQINSYR 736
Query: 189 CKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ- 362
C C ++G+ C+ G C G Y C+C GF+G C + I +
Sbjct: 737 CVCEAGWMGRNCDININECLSNPCVNGGTCKDMTSG---YLCTCRAGFSGPNCQMNINEC 793
Query: 363 ---PCI 371
PC+
Sbjct: 794 ASNPCL 799
Score = 45.1 bits (105), Expect = 2e-04
Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 7/104 (6%)
Frame = +3
Query: 78 GLYYNAQESKC---LKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXX 248
G+Y + C + +S + C++ G C++ G T+ C+C Y G C++
Sbjct: 1089 GIYCDVPSVSCEVAARQQGVSVAVLCRHAGQCVDAGNTHLCRCQAGYTGSYCQEQVDECQ 1148
Query: 249 XXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRI----YQPC 368
G G Y+C C G+ G C I QPC
Sbjct: 1149 PNPCQNGATCTDYLGG--YSCECVPGYHGMNCSKEINECLSQPC 1190
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/138 (23%), Positives = 47/138 (34%), Gaps = 2/138 (1%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKC 197
C N Y+C C G C N + C N G C++ ++ C C
Sbjct: 958 CTDCVNSYTCS------CPAGF----SGINCEINTPDCTESSCFNGGTCVDGISSFSCVC 1007
Query: 198 LDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCD--LRIYQPCI 371
L + G C+ G +G Y C+C G+TG C +R
Sbjct: 1008 LPGFTGNYCQHDVNECDSRPCQNGGSCQDGYG--TYKCTCPHGYTGLNCQSLVRWCDSSP 1065
Query: 372 CPKNMKCNYSESGALFSC 425
C C + GA F+C
Sbjct: 1066 CKNGGSC--WQQGASFTC 1081
Score = 44.3 bits (103), Expect = 4e-04
Identities = 34/118 (28%), Positives = 44/118 (37%), Gaps = 10/118 (8%)
Frame = +3
Query: 24 PIENEYSC-DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCL 200
P +N +C D G C Y+ N C+S CQN G CI+ TY+C C
Sbjct: 1151 PCQNGATCTDYLGGYSCECVPGYHGMNCSKEINECLSQ--PCQNGGTCIDLVNTYKCSCP 1208
Query: 201 DSYIGKLCE---------KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCD 347
G CE G+C + G Y C C GF GE+C+
Sbjct: 1209 RGTQGVHCEIDIDDCSPSVDPLTGEPRCFNGGRCVDRVGG---YGCVCPAGFVGERCE 1263
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/133 (24%), Positives = 52/133 (39%), Gaps = 4/133 (3%)
Frame = +3
Query: 18 CFPIENEYSCD---GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C N+Y+C+ GF G++ ++C + C + G C + ++
Sbjct: 541 CTDGPNKYTCECTPGFS------GIHCELDINECASSPC--------HYGVCRDGVASFT 586
Query: 189 CKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQP 365
C C Y G+LCE G C + Y C+C +G TG C++ I
Sbjct: 587 CDCRPGYTGRLCETNINECLSQPCRNGGTC---QDRENAYICTCPKGTTGVNCEINI-DD 642
Query: 366 CICPKNMKCNYSE 404
C K C+Y +
Sbjct: 643 C---KRKPCDYGK 652
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
Frame = +3
Query: 117 NNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEK-XXXXXXXXXXXXGKCFVQNHG 293
N C S CQN G C + TY+C C Y G C+ G C+ Q
Sbjct: 1021 NECDSR--PCQNGGSCQDGYGTYKCTCPHGYTGLNCQSLVRWCDSSPCKNGGSCWQQGAS 1078
Query: 294 DKLYACSCSEGFTGEKCDL 350
+ C C+ G+TG CD+
Sbjct: 1079 ---FTCQCASGWTGIYCDV 1094
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/122 (22%), Positives = 44/122 (36%), Gaps = 8/122 (6%)
Frame = +3
Query: 6 CTTFCFPIENEYSCDGFGNKICREGLY-------YNAQESKCLKNNCISSNIQCQNNGYC 164
C+ P+ E C G + R G Y + + + N C+S + C
Sbjct: 1223 CSPSVDPLTGEPRCFNGGRCVDRVGGYGCVCPAGFVGERCEGDVNECLSDPCDPSGSYNC 1282
Query: 165 INNGLTYECKCLDSYIGKLCEK-XXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEK 341
+ + C+C Y GK CE G C V ++ Y C C G++G
Sbjct: 1283 VQLINDFRCECRTGYTGKRCETVFNGCKDTPCKNGGTCAVASNTKHGYICKCQPGYSGSS 1342
Query: 342 CD 347
C+
Sbjct: 1343 CE 1344
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/131 (25%), Positives = 47/131 (35%), Gaps = 8/131 (6%)
Frame = +3
Query: 24 PIENEYSCDG---FGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECK 194
P + +CD G IC Y + C C++ G C+N +++CK
Sbjct: 379 PCQKGSNCDTNPVSGKAICTCPPGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCK 438
Query: 195 CLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLR----IY 359
CL Y G CE C Q G + C C G+ G C +
Sbjct: 439 CLQGYEGPRCEMDVNECKSNPCQNDATCLDQIGG---FHCICMPGYEGVFCQINSDDCAS 495
Query: 360 QPCICPKNMKC 392
QPC+ N KC
Sbjct: 496 QPCL---NGKC 503
Score = 39.3 bits (90), Expect = 0.013
Identities = 36/150 (24%), Positives = 48/150 (32%), Gaps = 4/150 (2%)
Frame = +3
Query: 30 ENEYSC-DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDS 206
EN C DG C ++ Q + C S CQN G C N + C C++
Sbjct: 266 ENGGPCIDGINTYNCHCDKHWTGQYCTEDVDECELSPNACQNGGTCHNTIGGFHCVCVNG 325
Query: 207 YIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKC---DLRIYQPCICP 377
+ G C + G + C C G TG C D I PC
Sbjct: 326 WTGDDCSENIDDCASAACSHGATCHDRVAS--FFCECPHGRTGLLCHLDDACISNPCQKG 383
Query: 378 KNMKCNYSESGALFSCTSENEADSSNPKSD 467
N N A+ +C + N D
Sbjct: 384 SNCDTNPVSGKAICTCPPGYTGSACNQDID 413
Score = 38.9 bits (89), Expect = 0.017
Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Frame = +3
Query: 135 NIQCQNNGYCINNGL-TYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFV-QNHGDKLYA 308
N C+N G C L T+ C+C + GK C+ G+C ++H Y
Sbjct: 107 NSPCRNGGTCSLLTLDTFTCRCQPGWSGKTCQLADPCASNPCANGGQCSAFESH----YI 162
Query: 309 CSCSEGFTGEKCDLRIYQPCICP 377
C+C F G+ C + + + P
Sbjct: 163 CTCPPNFHGQTCRQDVNECAVSP 185
Score = 38.1 bits (87), Expect = 0.029
Identities = 28/108 (25%), Positives = 36/108 (33%), Gaps = 5/108 (4%)
Frame = +3
Query: 48 DGFGNKICR-----EGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYI 212
D +CR G Y Q +C N CQN C + Y C+C+ Y
Sbjct: 1122 DAGNTHLCRCQAGYTGSYCQEQVDECQPN-------PCQNGATCTDYLGGYSCECVPGYH 1174
Query: 213 GKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRI 356
G C K G + Y CSC G G C++ I
Sbjct: 1175 GMNCSKEINECLSQPCQNGGTCIDLVNT--YKCSCPRGTQGVHCEIDI 1220
Score = 37.0 bits (84), Expect = 0.064
Identities = 22/76 (28%), Positives = 31/76 (40%)
Frame = +3
Query: 117 NNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGD 296
+ C+S+ C+N G C + +Y C C + G CE G V G
Sbjct: 945 DECVSA--PCRNGGNCTDCVNSYTCSCPAGFSGINCEINTPDCTESSCFNGGTCVD--GI 1000
Query: 297 KLYACSCSEGFTGEKC 344
++C C GFTG C
Sbjct: 1001 SSFSCVCLPGFTGNYC 1016
Score = 35.4 bits (80), Expect = 0.19
Identities = 21/74 (28%), Positives = 29/74 (39%), Gaps = 3/74 (4%)
Frame = +3
Query: 144 CQNNGYCINNGLTYECKCLDSYIGKLCEK---XXXXXXXXXXXXGKCFVQNHGDKLYACS 314
C+N G CI+ TY C C + G+ C + G C G + C
Sbjct: 265 CENGGPCIDGINTYNCHCDKHWTGQYCTEDVDECELSPNACQNGGTCHNTIGG---FHCV 321
Query: 315 CSEGFTGEKCDLRI 356
C G+TG+ C I
Sbjct: 322 CVNGWTGDDCSENI 335
Score = 35.4 bits (80), Expect = 0.19
Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 1/70 (1%)
Frame = +3
Query: 144 CQNNGYCINNGLTYECKCLDSYIGKLC-EKXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 320
C N G C + + C CL + G+ C E G C Y CSC
Sbjct: 914 CSNGGVCQDRVNGFVCVCLAGFRGERCAEDIDECVSAPCRNGGNC---TDCVNSYTCSCP 970
Query: 321 EGFTGEKCDL 350
GF+G C++
Sbjct: 971 AGFSGINCEI 980
Score = 35.4 bits (80), Expect = 0.19
Identities = 20/87 (22%), Positives = 32/87 (36%), Gaps = 1/87 (1%)
Frame = +3
Query: 102 SKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFV 281
S C ++ +++C+N C++ L+ C C + G C+
Sbjct: 1341 SSCEYDSQSCGSLRCRNGATCVSGHLSPRCLCAPGFSGHECQTRMDSPCLVNPCYNGGTC 1400
Query: 282 QNHGDK-LYACSCSEGFTGEKCDLRIY 359
Q D Y CSC F G C + Y
Sbjct: 1401 QPISDAPFYRCSCPANFNGLLCHILDY 1427
>sp|P24014|SLIT_DROME Slit protein precursor [Contains: Slit protein N-product; Slit
protein C-product]
Length = 1504
Score = 58.2 bits (139), Expect = 3e-08
Identities = 35/119 (29%), Positives = 45/119 (37%), Gaps = 9/119 (7%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKC 197
C YSCD C+ G + + C N N CQN G C++ Y+C+C
Sbjct: 1065 CMDHFTHYSCD------CQAGFH----GTNCTDNIDDCQNHMCQNGGTCVDGINDYQCRC 1114
Query: 198 LDSYIGKLCE---------KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCD 347
D Y GK CE G CF N Y C C G+TG+ C+
Sbjct: 1115 PDDYTGKYCEGHNMISMMYPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWCE 1173
Score = 45.8 bits (107), Expect = 1e-04
Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 19/136 (13%)
Frame = +3
Query: 18 CF--PIENEYSCDGFGNK----ICREGLYYNAQESKCLKNNCISSNIQCQNNGYC--INN 173
CF P +N+ C + +C+ G Y+ + + + + C + C+NN C +
Sbjct: 935 CFEQPCQNQAQCVALPQREYQCLCQPG--YHGKHCEFMIDACYGN--PCRNNATCTVLEE 990
Query: 174 GLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNH-----GDKLYACSCSEGFTGE 338
G + C+C Y G CE G+ QN+ G + Y C C GF+GE
Sbjct: 991 G-RFSCQCAPGYTGARCETNIDDCL------GEIKCQNNATCIDGVESYKCECQPGFSGE 1043
Query: 339 KCDLRI------YQPC 368
CD +I + PC
Sbjct: 1044 FCDTKIQFCSPEFNPC 1059
Score = 43.9 bits (102), Expect = 5e-04
Identities = 29/108 (26%), Positives = 45/108 (41%), Gaps = 3/108 (2%)
Frame = +3
Query: 30 ENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSY 209
E +SC C G Y + ++C+ I+CQNN CI+ +Y+C+C +
Sbjct: 990 EGRFSCQ------CAPG--YTGARCETNIDDCLGE-IKCQNNATCIDGVESYKCECQPGF 1040
Query: 210 IGKLCE---KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKC 344
G+ C+ + KC +H Y+C C GF G C
Sbjct: 1041 SGEFCDTKIQFCSPEFNPCANGAKC--MDHFTH-YSCDCQAGFHGTNC 1085
>sp|P21783|NOTCH_XENLA Neurogenic locus notch protein homolog precursor (XOTCH protein)
Length = 2524
Score = 58.2 bits (139), Expect = 3e-08
Identities = 38/156 (24%), Positives = 61/156 (39%), Gaps = 6/156 (3%)
Frame = +3
Query: 18 CFPIENEYSCD---GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C NE+ CD GF +C+ + C S+ C+N C++ +Y
Sbjct: 504 CIDKINEFRCDCPTGFSGNLCQHDF-----------DECTST--PCKNGAKCLDGPNSYT 550
Query: 189 CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPC 368
C+C + + G+ CE+ G C G + C C G+TG CD I + C
Sbjct: 551 CQCTEGFTGRHCEQDINECIPDPCHYGTC---KDGIATFTCLCRPGYTGRLCDNDINE-C 606
Query: 369 I---CPKNMKCNYSESGALFSCTSENEADSSNPKSD 467
+ C +C E+G + +C + K D
Sbjct: 607 LSKPCLNGGQCTDRENGYICTCPKGTTGVNCETKID 642
Score = 57.0 bits (136), Expect = 6e-08
Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 3/125 (2%)
Frame = +3
Query: 18 CFPIENEYSCD---GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C P E +Y C GF C++ + N C S C+N G CIN +Y
Sbjct: 156 CLPFEIQYICKCPPGFHGATCKQDI-----------NEC--SQNPCKNGGQCINEFGSYR 202
Query: 189 CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPC 368
C C + + G+ C++ G Q D Y C+C GF+G+ C+ I
Sbjct: 203 CTCQNRFTGRNCDEPYVPCNPSPCLNGGTCRQT-DDTSYDCTCLPGFSGQNCEENIDD-- 259
Query: 369 ICPKN 383
CP N
Sbjct: 260 -CPSN 263
Score = 56.2 bits (134), Expect = 1e-07
Identities = 43/144 (29%), Positives = 59/144 (40%), Gaps = 10/144 (6%)
Frame = +3
Query: 24 PIENEYSC-DGFGNKIC-----REGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTY 185
P +N+ +C D G C EGLY +C N C+ +NG CI+ +
Sbjct: 459 PCQNDSTCLDQIGEFQCICMPGYEGLYCETNIDECASNPCL-------HNGKCIDKINEF 511
Query: 186 ECKCLDSYIGKLCEKXXXXXXXXXXXXG-KCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ 362
C C + G LC+ G KC G Y C C+EGFTG C+ I +
Sbjct: 512 RCDCPTGFSGNLCQHDFDECTSTPCKNGAKCL---DGPNSYTCQCTEGFTGRHCEQDINE 568
Query: 363 PCICPKNMKCNY---SESGALFSC 425
CI C+Y + A F+C
Sbjct: 569 -CIPD---PCHYGTCKDGIATFTC 588
Score = 53.9 bits (128), Expect = 5e-07
Identities = 40/161 (24%), Positives = 70/161 (43%), Gaps = 1/161 (0%)
Frame = +3
Query: 24 PIENEYSC-DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCL 200
P N +C D G IC ++ + N C S+ C N+G CI++ Y+C C+
Sbjct: 760 PCMNGGTCKDMTGAYICTCKAGFSGPNCQTNINECSSN--PCLNHGTCIDDVAGYKCNCM 817
Query: 201 DSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPCICPK 380
Y G +CE G ++ + ++C C G+ G+ C++ + + C+
Sbjct: 818 LPYTGAICEAVLAPCAGSPCKNGGRCKESEDFETFSCECPPGWQGQTCEIDMNE-CV--- 873
Query: 381 NMKCNYSESGALFSCTSENEADSSNPKSDYSNRKVKQNWKD 503
N C +GA +C + N + N K Y+ R + + D
Sbjct: 874 NRPC---RNGA--TCQNTNGSYKCNCKPGYTGRNCEMDIDD 909
Score = 51.6 bits (122), Expect = 3e-06
Identities = 37/146 (25%), Positives = 53/146 (36%), Gaps = 7/146 (4%)
Frame = +3
Query: 9 TTFCFPIENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCI---NNGL 179
T C + N+Y C+ CR+G + + + + + C + C+N G C N
Sbjct: 1280 TQNCIQLVNDYRCE------CRQG--FTGRRCESVVDGC--KGMPCRNGGTCAVASNTER 1329
Query: 180 TYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRI 356
+ CKC + G CE G C K C CSEG+TG C +
Sbjct: 1330 GFICKCPPGFDGATCEYDSRTCSNLRCQNGGTCISVLTSSK---CVCSEGYTGATCQYPV 1386
Query: 357 YQPCI---CPKNMKCNYSESGALFSC 425
PC C C + F C
Sbjct: 1387 ISPCASHPCYNGGTCQFFAEEPFFQC 1412
Score = 50.1 bits (118), Expect = 7e-06
Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +3
Query: 117 NNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXG-KCFVQNHG 293
N C+ N C+N C N +Y+C C Y G+ CE G C + G
Sbjct: 870 NECV--NRPCRNGATCQNTNGSYKCNCKPGYTGRNCEMDIDDCQPNPCHNGGSC---SDG 924
Query: 294 DKLYACSCSEGFTGEKCDLRIYQPCICPKNMKCNYSESGALFSCTSE 434
++ C+C GF G KC+ I + P N ++ ++CT +
Sbjct: 925 INMFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQ 971
Score = 48.1 bits (113), Expect = 3e-05
Identities = 32/127 (25%), Positives = 48/127 (37%), Gaps = 10/127 (7%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREG---LYYNAQESKC---LKNNCISSNIQCQNNGYCINNGL 179
C+ N Y C+ C+ G +Y + C K + C+N+G C++ G
Sbjct: 1073 CWQTNNFYRCE------CKSGWTGVYCDVPSVSCEVAAKQQGVDIVHLCRNSGMCVDTGN 1126
Query: 180 TYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIY 359
T+ C+C Y G CE+ G G Y+C C G+ G C I
Sbjct: 1127 THFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGG--YSCECVAGYHGVNCSEEIN 1184
Query: 360 Q----PC 368
+ PC
Sbjct: 1185 ECLSHPC 1191
Score = 47.8 bits (112), Expect = 4e-05
Identities = 45/171 (26%), Positives = 65/171 (38%), Gaps = 15/171 (8%)
Frame = +3
Query: 3 QCTTF--CFPIENEYSCD-------GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNN 155
QC F C P+ + D GF +K+C + N C+ N C+N
Sbjct: 67 QCMNFGTCEPVLQGNAIDFICHCPVGFTDKVCLTPV----------DNACV--NNPCRNG 114
Query: 156 GYC--INNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGF 329
G C +N+ Y+C+C + G C++ GKC + Y C C GF
Sbjct: 115 GTCELLNSVTEYKCRCPPGWTGDSCQQADPCASNPCANGGKCL---PFEIQYICKCPPGF 171
Query: 330 TGEKCDLRIYQ----PCICPKNMKCNYSESGALFSCTSENEADSSNPKSDY 470
G C I + PC KN +E G+ + CT +N N Y
Sbjct: 172 HGATCKQDINECSQNPC---KNGGQCINEFGS-YRCTCQNRFTGRNCDEPY 218
Score = 47.0 bits (110), Expect = 6e-05
Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 4/105 (3%)
Frame = +3
Query: 66 ICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXX 245
+CR G Y + N C+S C N G C + Y C C G CE
Sbjct: 589 LCRPG--YTGRLCDNDINECLSK--PCLNGGQCTDRENGYICTCPKGTTGVNCETKIDDC 644
Query: 246 XXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ----PC 368
GKC + G Y C+C G+TG+ C++ I + PC
Sbjct: 645 ASNLCDNGKCIDKIDG---YECTCEPGYTGKLCNININECDSNPC 686
Score = 46.2 bits (108), Expect = 1e-04
Identities = 34/137 (24%), Positives = 51/137 (37%), Gaps = 8/137 (5%)
Frame = +3
Query: 6 CTTFCFPIENEYSCDGFGNKICREGLY-------YNAQESKCLKNNCISSNIQCQNNGYC 164
CT F E C G I R G Y + + + N C+S+ + C
Sbjct: 1224 CTPFYDSFTLEPKCFNNGKCIDRVGGYNCICPPGFVGERCEGDVNECLSNPCDSRGTQNC 1283
Query: 165 INNGLTYECKCLDSYIGKLCEK-XXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEK 341
I Y C+C + G+ CE G C V ++ ++ + C C GF G
Sbjct: 1284 IQLVNDYRCECRQGFTGRRCESVVDGCKGMPCRNGGTCAVASNTERGFICKCPPGFDGAT 1343
Query: 342 CDLRIYQPCICPKNMKC 392
C+ Y C N++C
Sbjct: 1344 CE---YDSRTC-SNLRC 1356
Score = 45.8 bits (107), Expect = 1e-04
Identities = 43/168 (25%), Positives = 65/168 (38%), Gaps = 19/168 (11%)
Frame = +3
Query: 30 ENEYSCD---GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCL 200
+ Y C GF + C E + ++C S+N C+N G C++ TY C+C
Sbjct: 237 DTSYDCTCLPGFSGQNCEENI-----------DDCPSNN--CRNGGTCVDGVNTYNCQCP 283
Query: 201 DSYIGKLCEK---XXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRI----- 356
+ G+ C + G C G Y C C G+TGE C I
Sbjct: 284 PDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGG---YNCVCVNGWTGEDCSENIDDCAN 340
Query: 357 ---YQPCICPKNM-----KCNYSESGALFSCTSENEADSSNPKSDYSN 476
+ C + +C + +G L C +N A SNP ++ SN
Sbjct: 341 AACHSGATCHDRVASFYCECPHGRTGLL--CHLDN-ACISNPCNEGSN 385
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/130 (23%), Positives = 49/130 (37%), Gaps = 5/130 (3%)
Frame = +3
Query: 18 CFPIENEYSCD---GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C N Y+C GF G++ + C +++C N G CI+ T+
Sbjct: 959 CTDCVNSYTCTCQPGFS------GIHCESNTPDCTESSCF-------NGGTCIDGINTFT 1005
Query: 189 CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCD--LRIYQ 362
C+C + G C+ G ++G Y C+C +G+TG C +R
Sbjct: 1006 CQCPPGFTGSYCQHDINECDSKPCLNGGTCQDSYG--TYKCTCPQGYTGLNCQNLVRWCD 1063
Query: 363 PCICPKNMKC 392
C KC
Sbjct: 1064 SSPCKNGGKC 1073
Score = 45.1 bits (105), Expect = 2e-04
Identities = 26/87 (29%), Positives = 36/87 (41%)
Frame = +3
Query: 108 CLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQN 287
C + + +SN C N G C+ + Y CKC + G C++ G +
Sbjct: 139 CQQADPCASN-PCANGGKCLPFEIQYICKCPPGFHGATCKQDINECSQNPCKNGGQCINE 197
Query: 288 HGDKLYACSCSEGFTGEKCDLRIYQPC 368
G Y C+C FTG CD Y PC
Sbjct: 198 FGS--YRCTCQNRFTGRNCD-EPYVPC 221
Score = 44.7 bits (104), Expect = 3e-04
Identities = 36/117 (30%), Positives = 46/117 (39%), Gaps = 9/117 (7%)
Frame = +3
Query: 24 PIENEYSC-DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCL 200
P +N +C D G C Y+ N C+S CQN G CI+ TY+C C
Sbjct: 1152 PCQNGATCTDYLGGYSCECVAGYHGVNCSEEINECLSH--PCQNGGTCIDLINTYKCSCP 1209
Query: 201 DSYIGKLCE---KXXXXXXXXXXXXGKCFVQNHGDKL-----YACSCSEGFTGEKCD 347
G CE KCF N+G + Y C C GF GE+C+
Sbjct: 1210 RGTQGVHCEINVDDCTPFYDSFTLEPKCF--NNGKCIDRVGGYNCICPPGFVGERCE 1264
Score = 43.9 bits (102), Expect = 5e-04
Identities = 38/140 (27%), Positives = 47/140 (33%), Gaps = 4/140 (2%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKC 197
C N Y CD C G S C NN + C N G C + Y C C
Sbjct: 729 CHDGVNGYKCD------CEAGW----SGSNCDINNNECESNPCMNGGTCKDMTGAYICTC 778
Query: 198 LDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPCI- 371
+ G C+ G C G Y C+C +TG C+ + PC
Sbjct: 779 KAGFSGPNCQTNINECSSNPCLNHGTCIDDVAG---YKCNCMLPYTGAICE-AVLAPCAG 834
Query: 372 --CPKNMKCNYSESGALFSC 425
C +C SE FSC
Sbjct: 835 SPCKNGGRCKESEDFETFSC 854
Score = 43.5 bits (101), Expect = 7e-04
Identities = 44/161 (27%), Positives = 58/161 (36%), Gaps = 14/161 (8%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREGLYYNAQESK---CLKNNCISSNIQCQNNGYCINNGLTYE 188
C EN Y C C +G E+K C N C +NG CI+ YE
Sbjct: 617 CTDRENGYICT------CPKGTTGVNCETKIDDCASNLC--------DNGKCIDKIDGYE 662
Query: 189 CKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ- 362
C C Y GKLC G C Q +G + C C +G+ C + +
Sbjct: 663 CTCEPGYTGKLCNININECDSNPCRNGGTCKDQING---FTCVCPDGYHDHMCLSEVNEC 719
Query: 363 ---PCI---CPKNM---KCNYSESGALFSCTSENEADSSNP 458
PCI C + KC+ + +C N SNP
Sbjct: 720 NSNPCIHGACHDGVNGYKCDCEAGWSGSNCDINNNECESNP 760
Score = 42.7 bits (99), Expect = 0.001
Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 3/99 (3%)
Frame = +3
Query: 141 QCQNNGYCINNGLTYECKCLDSYIGKLCE---KXXXXXXXXXXXXGKCFVQNHGDKLYAC 311
+C NNG CI+ Y C C ++G+ CE C +Q D Y C
Sbjct: 1236 KCFNNGKCIDRVGGYNCICPPGFVGERCEGDVNECLSNPCDSRGTQNC-IQLVND--YRC 1292
Query: 312 SCSEGFTGEKCDLRIYQPCICPKNMKCNYSESGALFSCT 428
C +GFTG +C+ + C K M C + A+ S T
Sbjct: 1293 ECRQGFTGRRCE-SVVDGC---KGMPCRNGGTCAVASNT 1327
Score = 40.4 bits (93), Expect = 0.006
Identities = 31/121 (25%), Positives = 43/121 (35%), Gaps = 5/121 (4%)
Frame = +3
Query: 24 PIENEYSC-DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCL 200
P N SC DG C + + + N C S+ C+N C + +Y C C
Sbjct: 914 PCHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECASN--PCKNGANCTDCVNSYTCTCQ 971
Query: 201 DSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ----PC 368
+ G CE G + G + C C GFTG C I + PC
Sbjct: 972 PGFSGIHCESNTPDCTESSCFNGGTCID--GINTFTCQCPPGFTGSYCQHDINECDSKPC 1029
Query: 369 I 371
+
Sbjct: 1030 L 1030
Score = 39.3 bits (90), Expect = 0.013
Identities = 35/147 (23%), Positives = 50/147 (34%), Gaps = 11/147 (7%)
Frame = +3
Query: 24 PIENEYSC-DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCL 200
P N +C D +G C Y + L C SS C+N G C Y C+C
Sbjct: 1028 PCLNGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSS--PCKNGGKCWQTNNFYRCECK 1085
Query: 201 DSYIGKLCEKXXXXXXXXXXXXGKCFV---QNHG-----DKLYACSCSEGFTGEKCDLRI 356
+ G C+ G V +N G + C C G+TG C+ ++
Sbjct: 1086 SGWTGVYCDVPSVSCEVAAKQQGVDIVHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQV 1145
Query: 357 YQ--PCICPKNMKCNYSESGALFSCTS 431
+ P C C G C +
Sbjct: 1146 DECSPNPCQNGATCTDYLGGYSCECVA 1172
Score = 38.9 bits (89), Expect = 0.017
Identities = 21/86 (24%), Positives = 36/86 (41%), Gaps = 1/86 (1%)
Frame = +3
Query: 108 CLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQN 287
C ++ SN++CQN G CI+ + +C C + Y G C+ Q
Sbjct: 1344 CEYDSRTCSNLRCQNGGTCISVLTSSKCVCSEGYTGATCQYPVISPCASHPCYNGGTCQF 1403
Query: 288 HGDK-LYACSCSEGFTGEKCDLRIYQ 362
++ + C C + F G C + Y+
Sbjct: 1404 FAEEPFFQCFCPKNFNGLFCHILDYE 1429
Score = 37.0 bits (84), Expect = 0.064
Identities = 22/87 (25%), Positives = 34/87 (39%), Gaps = 4/87 (4%)
Frame = +3
Query: 144 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 323
C++ G C N +++C C Y G CE + G+ + C C
Sbjct: 422 CEHGGRCTNTLGSFQCNCPQGYAGPRCEIDVNECLSNPCQNDSTCLDQIGE--FQCICMP 479
Query: 324 GFTGEKCDLRIYQ----PCICPKNMKC 392
G+ G C+ I + PC+ N KC
Sbjct: 480 GYEGLYCETNIDECASNPCL--HNGKC 504
Score = 32.7 bits (73), Expect = 1.2
Identities = 18/80 (22%), Positives = 28/80 (35%)
Frame = +3
Query: 108 CLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQN 287
C +N +N C + C + ++ C+C G LC C
Sbjct: 331 CSENIDDCANAACHSGATCHDRVASFYCECPHGRTGLLCHLDNACISNPCNEGSNCDTNP 390
Query: 288 HGDKLYACSCSEGFTGEKCD 347
K C+C G+TG C+
Sbjct: 391 VNGKAI-CTCPPGYTGPACN 409
>sp|Q63722|JAG1_RAT Jagged-1 precursor (Jagged1)
Length = 1219
Score = 55.1 bits (131), Expect = 2e-07
Identities = 39/165 (23%), Positives = 62/165 (37%), Gaps = 25/165 (15%)
Frame = +3
Query: 6 CTTFCFPIEN---EYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINN- 173
C FC P ++ Y+CD GNK C EG + C + C+ G C
Sbjct: 196 CNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNKAICRQGCSPKHGSCKLPGDCRCQY 255
Query: 174 ---GL------------------TYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNH 290
GL ++C C ++ G+LC+K + N
Sbjct: 256 GWQGLYCDKCIPHPGCVHGTCNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNRGTCSNT 315
Query: 291 GDKLYACSCSEGFTGEKCDLRIYQPCICPKNMKCNYSESGALFSC 425
G Y CSC EG++G C++ + P + + + E+ + F C
Sbjct: 316 GPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSSGFEC 360
Score = 50.1 bits (118), Expect = 7e-06
Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 5/97 (5%)
Frame = +3
Query: 93 AQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLC-EKXXXXXXXXXXXXG 269
A+ S CL N C N G C+ NG ++ C C + + G +C + G
Sbjct: 743 ARNSSCLPN-------PCHNGGTCVVNGDSFTCVCKEGWEGPICTQNTNDCSPHPCYNSG 795
Query: 270 KCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ----PC 368
C GD Y C C+ GF G C + I + PC
Sbjct: 796 TCV---DGDNWYRCECAPGFAGPDCRININECQSSPC 829
Score = 45.1 bits (105), Expect = 2e-04
Identities = 32/120 (26%), Positives = 47/120 (39%), Gaps = 2/120 (1%)
Frame = +3
Query: 117 NNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGD 296
N+C+ QCQN+ C + Y C C Y G CE+ G QN +
Sbjct: 452 NDCLG---QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGG-HCQNEIN 507
Query: 297 KLYACSCSEGFTGEKCDLRI--YQPCICPKNMKCNYSESGALFSCTSENEADSSNPKSDY 470
+ + C C GF+G C L I +P C +C S C + E + + D+
Sbjct: 508 R-FQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDH 566
Score = 40.8 bits (94), Expect = 0.004
Identities = 31/120 (25%), Positives = 46/120 (38%), Gaps = 4/120 (3%)
Frame = +3
Query: 24 PIENEYSCDGFGNK---ICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECK 194
P N +C G+ +C+EG + C +N S C N+G C++ Y C+
Sbjct: 752 PCHNGGTCVVNGDSFTCVCKEGW----EGPICTQNTNDCSPHPCYNSGTCVDGDNWYRCE 807
Query: 195 CLDSYIGKLCEKXXXXXXXXXXXXGK-CFVQNHGDKLYACSCSEGFTGEKCDLRIYQPCI 371
C + G C G C + +G Y C C G +G KC + CI
Sbjct: 808 CAPGFAGPDCRININECQSSPCAFGATCVDEING---YQCICPPGHSGAKCHEVSGRSCI 864
Score = 40.4 bits (93), Expect = 0.006
Identities = 29/114 (25%), Positives = 46/114 (40%), Gaps = 5/114 (4%)
Frame = +3
Query: 18 CFPIENEYSCD---GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C + N++ CD G+ K C ++++S+C C N G C + T++
Sbjct: 682 CRDLVNDFYCDCKNGWKGKTC------HSRDSQC-------DEATCNNGGTCYDEVDTFK 728
Query: 189 CKCLDSYIGKLCE--KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKC 344
C C + G C + G C V +GD + C C EG+ G C
Sbjct: 729 CMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVV--NGDS-FTCVCKEGWEGPIC 779
Score = 40.0 bits (92), Expect = 0.008
Identities = 36/168 (21%), Positives = 52/168 (30%), Gaps = 32/168 (19%)
Frame = +3
Query: 18 CFPIENEYSC---DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C + N Y C G+ C + +C N C+ N G+C N ++
Sbjct: 464 CRDLVNGYRCICPPGYAGDHCERDI------DECASNPCL-------NGGHCQNEINRFQ 510
Query: 189 CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCD------- 347
C C + G LC+ G D Y C C E + G+ C
Sbjct: 511 CLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASD--YFCKCPEDYEGKNCSHLKDHCR 568
Query: 348 ----------------------LRIYQPCICPKNMKCNYSESGALFSC 425
+R +C + KC SESG F+C
Sbjct: 569 TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCK-SESGGKFTC 615
Score = 40.0 bits (92), Expect = 0.008
Identities = 28/109 (25%), Positives = 41/109 (37%), Gaps = 3/109 (2%)
Frame = +3
Query: 36 EYSCD---GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDS 206
+++CD GF C E + N+C + C N G CI+ +Y+C C D
Sbjct: 612 KFTCDCNKGFTGTYCHENI-----------NDCEGN--PCTNGGTCIDGVNSYKCICSDG 658
Query: 207 YIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLR 353
+ G CE G D + C C G+ G+ C R
Sbjct: 659 WEGAHCENNINDCSQNPCHYGGTCRDLVND--FYCDCKNGWKGKTCHSR 705
Score = 37.7 bits (86), Expect = 0.037
Identities = 29/124 (23%), Positives = 47/124 (37%), Gaps = 5/124 (4%)
Frame = +3
Query: 33 NEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYI 212
++Y C C EG Y+ + ++ C+S C N G C +EC+C +
Sbjct: 318 DKYQCS------CPEG--YSGPNCEIAEHACLSD--PCHNRGSCKETSSGFECECSPGWT 367
Query: 213 GKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ----PCICP 377
G C G C +G + C C +TG+ C L + PC+
Sbjct: 368 GPTCSTNIDDCSPNNCSHGGTCQDLVNG---FKCVCPPQWTGKTCQLDANECEAKPCVNA 424
Query: 378 KNMK 389
++ K
Sbjct: 425 RSCK 428
Score = 35.4 bits (80), Expect = 0.19
Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 4/80 (5%)
Frame = +3
Query: 144 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 323
C N C N +Y C CL ++G+ C+ C +G Y C C
Sbjct: 421 CVNARSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNG---YRCICPP 477
Query: 324 GFTGEKCDLRIYQ----PCI 371
G+ G+ C+ I + PC+
Sbjct: 478 GYAGDHCERDIDECASNPCL 497
Score = 35.4 bits (80), Expect = 0.19
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 1/92 (1%)
Frame = +3
Query: 126 ISSNIQCQNNGYCIN-NGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKL 302
ISSN+ C +G C + +G + C C + G C + G + G
Sbjct: 594 ISSNV-CGPHGKCKSESGGKFTCDCNKGFTGTYCHENINDCEGNPCTNGGTCID--GVNS 650
Query: 303 YACSCSEGFTGEKCDLRIYQPCICPKNMKCNY 398
Y C CS+G+ G C+ I C +N C+Y
Sbjct: 651 YKCICSDGWEGAHCENNIND---CSQN-PCHY 678
Score = 32.3 bits (72), Expect = 1.6
Identities = 26/119 (21%), Positives = 41/119 (34%), Gaps = 1/119 (0%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKC 197
C N Y C IC +G + + C N S C G C + + C C
Sbjct: 644 CIDGVNSYKC------ICSDGW----EGAHCENNINDCSQNPCHYGGTCRDLVNDFYCDC 693
Query: 198 LDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPCI 371
+ + GK C + G C+ + + C C G+ G C++ C+
Sbjct: 694 KNGWKGKTCHSRDSQCDEATCNNGGTCYDEVD---TFKCMCPGGWEGTTCNIARNSSCL 749
>sp|Q9QXX0|JAG1_MOUSE Jagged-1 precursor (Jagged1)
Length = 1218
Score = 54.7 bits (130), Expect = 3e-07
Identities = 39/165 (23%), Positives = 62/165 (37%), Gaps = 25/165 (15%)
Frame = +3
Query: 6 CTTFCFPIEN---EYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINN- 173
C FC P ++ Y+CD GNK C EG + C + C+ G C
Sbjct: 196 CNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPDCNKAICRQGCSPKHGSCKLPGDCRCQY 255
Query: 174 ---GL------------------TYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNH 290
GL ++C C ++ G+LC+K + N
Sbjct: 256 GWQGLYCDKCIPHPGCVHGTCNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNRGTCSNT 315
Query: 291 GDKLYACSCSEGFTGEKCDLRIYQPCICPKNMKCNYSESGALFSC 425
G Y CSC EG++G C++ + P + + + E+ + F C
Sbjct: 316 GPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSSGFEC 360
Score = 50.1 bits (118), Expect = 7e-06
Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 5/97 (5%)
Frame = +3
Query: 93 AQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLC-EKXXXXXXXXXXXXG 269
A+ S CL N C N G C+ NG ++ C C + + G +C + G
Sbjct: 743 ARNSSCLPN-------PCHNGGTCVVNGDSFTCVCKEGWEGPICTQNTNDCSPHPCYNSG 795
Query: 270 KCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ----PC 368
C GD Y C C+ GF G C + I + PC
Sbjct: 796 TCV---DGDNWYRCECAPGFAGPDCRININECQSSPC 829
Score = 45.1 bits (105), Expect = 2e-04
Identities = 32/120 (26%), Positives = 47/120 (39%), Gaps = 2/120 (1%)
Frame = +3
Query: 117 NNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGD 296
N+C+ QCQN+ C + Y C C Y G CE+ G QN +
Sbjct: 452 NDCLG---QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGG-HCQNEIN 507
Query: 297 KLYACSCSEGFTGEKCDLRI--YQPCICPKNMKCNYSESGALFSCTSENEADSSNPKSDY 470
+ + C C GF+G C L I +P C +C S C + E + + D+
Sbjct: 508 R-FQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDH 566
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 3/109 (2%)
Frame = +3
Query: 36 EYSCD---GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDS 206
+++CD GF C E + N+C S+ C+N G CI+ +Y+C C D
Sbjct: 612 KFTCDCNKGFTGTYCHENI-----------NDCESN--PCKNGGTCIDGVNSYKCICSDG 658
Query: 207 YIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLR 353
+ G CE G D + C C G+ G+ C R
Sbjct: 659 WEGAHCENNINDCSQNPCHYGGTCRDLVND--FYCDCKNGWKGKTCHSR 705
Score = 41.6 bits (96), Expect = 0.003
Identities = 34/135 (25%), Positives = 43/135 (31%), Gaps = 31/135 (22%)
Frame = +3
Query: 33 NEYSC---DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLD 203
N + C GF +C+ + Y C N CQN C N Y CKC +
Sbjct: 507 NRFQCLCPTGFSGNLCQLDIDY------CEPN-------PCQNGAQCYNRASDYFCKCPE 553
Query: 204 SYIGKLC----------------------------EKXXXXXXXXXXXXGKCFVQNHGDK 299
Y GK C E GKC Q+ G
Sbjct: 554 DYEGKNCSHLKDHCRTTTCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGK- 612
Query: 300 LYACSCSEGFTGEKC 344
+ C C++GFTG C
Sbjct: 613 -FTCDCNKGFTGTYC 626
Score = 40.8 bits (94), Expect = 0.004
Identities = 31/120 (25%), Positives = 46/120 (38%), Gaps = 4/120 (3%)
Frame = +3
Query: 24 PIENEYSCDGFGNK---ICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECK 194
P N +C G+ +C+EG + C +N S C N+G C++ Y C+
Sbjct: 752 PCHNGGTCVVNGDSFTCVCKEGW----EGPICTQNTNDCSPHPCYNSGTCVDGDNWYRCE 807
Query: 195 CLDSYIGKLCEKXXXXXXXXXXXXGK-CFVQNHGDKLYACSCSEGFTGEKCDLRIYQPCI 371
C + G C G C + +G Y C C G +G KC + CI
Sbjct: 808 CAPGFAGPDCRININECQSSPCAFGATCVDEING---YQCICPPGHSGAKCHEVSGRSCI 864
Score = 40.4 bits (93), Expect = 0.006
Identities = 29/114 (25%), Positives = 46/114 (40%), Gaps = 5/114 (4%)
Frame = +3
Query: 18 CFPIENEYSCD---GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C + N++ CD G+ K C ++++S+C C N G C + T++
Sbjct: 682 CRDLVNDFYCDCKNGWKGKTC------HSRDSQC-------DEATCNNGGTCYDEVDTFK 728
Query: 189 CKCLDSYIGKLCE--KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKC 344
C C + G C + G C V +GD + C C EG+ G C
Sbjct: 729 CMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVV--NGDS-FTCVCKEGWEGPIC 779
Score = 39.3 bits (90), Expect = 0.013
Identities = 26/112 (23%), Positives = 38/112 (33%), Gaps = 3/112 (2%)
Frame = +3
Query: 18 CFPIENEYSC---DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C + N Y C G+ C + +C N C+ N G+C N ++
Sbjct: 464 CRDLVNGYRCICPPGYAGDHCERDI------DECASNPCL-------NGGHCQNEINRFQ 510
Query: 189 CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKC 344
C C + G LC+ G D Y C C E + G+ C
Sbjct: 511 CLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASD--YFCKCPEDYEGKNC 560
Score = 37.7 bits (86), Expect = 0.037
Identities = 29/124 (23%), Positives = 47/124 (37%), Gaps = 5/124 (4%)
Frame = +3
Query: 33 NEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYI 212
++Y C C EG Y+ + ++ C+S C N G C +EC+C +
Sbjct: 318 DKYQCS------CPEG--YSGPNCEIAEHACLSD--PCHNRGSCKETSSGFECECSPGWT 367
Query: 213 GKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ----PCICP 377
G C G C +G + C C +TG+ C L + PC+
Sbjct: 368 GPTCSTNIDDCSPNNCSHGGTCQDLVNG---FKCVCPPQWTGKTCQLDANECEAKPCVNA 424
Query: 378 KNMK 389
++ K
Sbjct: 425 RSCK 428
Score = 35.4 bits (80), Expect = 0.19
Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 4/80 (5%)
Frame = +3
Query: 144 CQNNGYCINNGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSE 323
C N C N +Y C CL ++G+ C+ C +G Y C C
Sbjct: 421 CVNARSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNG---YRCICPP 477
Query: 324 GFTGEKCDLRIYQ----PCI 371
G+ G+ C+ I + PC+
Sbjct: 478 GYAGDHCERDIDECASNPCL 497
Score = 35.4 bits (80), Expect = 0.19
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 1/92 (1%)
Frame = +3
Query: 126 ISSNIQCQNNGYCIN-NGLTYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKL 302
ISSN+ C +G C + +G + C C + G C + G + G
Sbjct: 594 ISSNV-CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCKNGGTCID--GVNS 650
Query: 303 YACSCSEGFTGEKCDLRIYQPCICPKNMKCNY 398
Y C CS+G+ G C+ I C +N C+Y
Sbjct: 651 YKCICSDGWEGAHCENNIND---CSQN-PCHY 678
Score = 32.3 bits (72), Expect = 1.6
Identities = 26/119 (21%), Positives = 41/119 (34%), Gaps = 1/119 (0%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKC 197
C N Y C IC +G + + C N S C G C + + C C
Sbjct: 644 CIDGVNSYKC------ICSDGW----EGAHCENNINDCSQNPCHYGGTCRDLVNDFYCDC 693
Query: 198 LDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPCI 371
+ + GK C + G C+ + + C C G+ G C++ C+
Sbjct: 694 KNGWKGKTCHSRDSQCDEATCNNGGTCYDEVD---TFKCMCPGGWEGTTCNIARNSSCL 749
>sp|P49013|FBP3_STRPU Fibropellin C precursor (Epidermal growth factor-related protein 3)
(EGF III) (Fibropellin III)
Length = 570
Score = 54.7 bits (130), Expect = 3e-07
Identities = 38/121 (31%), Positives = 49/121 (40%), Gaps = 4/121 (3%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKC 197
C N Y+CD CR G + E+ N C SS C N G C++ Y C+C
Sbjct: 305 CTDAVNRYTCD------CRAGFTGSNCETNI--NECASS--PCLNGGSCLDGVDGYVCQC 354
Query: 198 LDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ----P 365
L +Y G CE G GD Y C C G+TG C++ I + P
Sbjct: 355 LPNYTGTHCEISLDACASLPCQNGGVCTNVGGD--YVCECLPGYTGINCEIDINECASLP 412
Query: 366 C 368
C
Sbjct: 413 C 413
Score = 53.9 bits (128), Expect = 5e-07
Identities = 34/110 (30%), Positives = 46/110 (41%), Gaps = 2/110 (1%)
Frame = +3
Query: 24 PIENEYSC-DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCL 200
P N SC DG +C+ Y + + C S + CQN G C N G Y C+CL
Sbjct: 336 PCLNGGSCLDGVDGYVCQCLPNYTGTHCEISLDACAS--LPCQNGGVCTNVGGDYVCECL 393
Query: 201 DSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCD 347
Y G CE G+C +G +Y C C +G+ G C+
Sbjct: 394 PGYTGINCEIDINECASLPCQNGGECI---NGIAMYICQCRQGYAGVNCE 440
Score = 50.4 bits (119), Expect = 6e-06
Identities = 36/126 (28%), Positives = 45/126 (35%), Gaps = 8/126 (6%)
Frame = +3
Query: 18 CFPIENEYSCD---GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C N Y+C+ GF C + N C S I C N G C++ +
Sbjct: 229 CVDQVNGYTCNCIPGFNGVNCENNI-----------NECAS--IPCLNGGICVDGINQFA 275
Query: 189 CKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ- 362
C CL Y G LCE G C Y C C GFTG C+ I +
Sbjct: 276 CTCLPGYTGILCETDINECASSPCQNGGSC---TDAVNRYTCDCRAGFTGSNCETNINEC 332
Query: 363 ---PCI 371
PC+
Sbjct: 333 ASSPCL 338
Score = 45.4 bits (106), Expect = 2e-04
Identities = 44/189 (23%), Positives = 73/189 (38%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKC 197
C N+Y C IC G + E+ + C S+ C+N G C++ Y C C
Sbjct: 191 CVDQVNDYQC------ICAPGFTGDNCETDI--DECASA--PCRNGGACVDQVNGYTCNC 240
Query: 198 LDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPCICP 377
+ + G CE G V G +AC+C G+TG C+ I + P
Sbjct: 241 IPGFNGVNCENNINECASIPCLNGGICVD--GINQFACTCLPGYTGILCETDINECASSP 298
Query: 378 KNMKCNYSESGALFSCTSENEADSSNPKSDYSNRKVKQNWKDVSLSTTIVAAVGCMTILI 557
++G SCT + + ++ ++ + N + + S+ + C+
Sbjct: 299 -------CQNGG--SCTDAVNRYTCDCRAGFTGSNCETNINECA-SSPCLNGGSCLD--- 345
Query: 558 SIGVSIYVC 584
GV YVC
Sbjct: 346 --GVDGYVC 352
Score = 39.7 bits (91), Expect = 0.010
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 5/81 (6%)
Frame = +3
Query: 144 CQNNGYCINNGLTYECKCLDSYIGKLCE-KXXXXXXXXXXXXGKCFVQNHGDKLYACSCS 320
C N C++ Y+C C + G CE G C Q +G Y C+C
Sbjct: 185 CLNGATCVDQVNDYQCICAPGFTGDNCETDIDECASAPCRNGGACVDQVNG---YTCNCI 241
Query: 321 EGFTGEKCDLRIYQ----PCI 371
GF G C+ I + PC+
Sbjct: 242 PGFNGVNCENNINECASIPCL 262
Score = 38.5 bits (88), Expect = 0.022
Identities = 23/71 (32%), Positives = 30/71 (42%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKC 197
C + +Y C+ C G Y + N C S + CQN G CIN Y C+C
Sbjct: 381 CTNVGGDYVCE------CLPG--YTGINCEIDINECAS--LPCQNGGECINGIAMYICQC 430
Query: 198 LDSYIGKLCEK 230
Y G CE+
Sbjct: 431 RQGYAGVNCEE 441
>sp|P14585|LIN12_CAEEL Lin-12 protein precursor
Length = 1429
Score = 54.3 bits (129), Expect = 4e-07
Identities = 30/113 (26%), Positives = 42/113 (37%), Gaps = 3/113 (2%)
Frame = +3
Query: 18 CFPIENEYSC---DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYE 188
C + C DG+ C+EG K+NC+ N +C+ CIN +Y
Sbjct: 264 CISFSGGFQCICDDGYSGSYCQEG-----------KDNCV--NNKCEAGSKCINGVNSYF 310
Query: 189 CKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCD 347
C C G CEK G C +K + C C G+ G C+
Sbjct: 311 CDCPPERTGPYCEKMDCSAIPDICNHGTCIDSPLSEKAFECQCEPGYEGILCE 363
Score = 49.7 bits (117), Expect = 1e-05
Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Frame = +3
Query: 114 KNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLC-EKXXXXXXXXXXXXGKCFVQNH 290
KN C+S N+ C NNG C+N ++ C C + GK C E G C +
Sbjct: 366 KNECLSENM-CLNNGTCVNLPGSFRCDCARGFGGKWCDEPLNMCQDFHCENDGTC--MHT 422
Query: 291 GDKLYACSCSEGFTGEKCD 347
D C C GF G++C+
Sbjct: 423 SDHSPVCQCKNGFIGKRCE 441
Score = 46.6 bits (109), Expect = 8e-05
Identities = 41/148 (27%), Positives = 59/148 (39%), Gaps = 18/148 (12%)
Frame = +3
Query: 18 CFPIENEYSCD---GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNG-LTY 185
C + + CD GFG K C E L N C + C+N+G C++ +
Sbjct: 381 CVNLPGSFRCDCARGFGGKWCDEPL-----------NMC--QDFHCENDGTCMHTSDHSP 427
Query: 186 ECKCLDSYIGKLCEK------------XXXXXXXXXXXXGKCFVQNHGDKLYA--CSCSE 323
C+C + +IGK CEK GKCF +G K + C C
Sbjct: 428 VCQCKNGFIGKRCEKECPIGFGGVRCDLRLEIGICSRQGGKCF---NGGKCLSGFCVCPP 484
Query: 324 GFTGEKCDLRIYQPCICPKNMKCNYSES 407
FTG +C++ KN K + SE+
Sbjct: 485 DFTGNQCEVN-------RKNGKSSLSEN 505
Score = 44.3 bits (103), Expect = 4e-04
Identities = 31/111 (27%), Positives = 43/111 (38%), Gaps = 5/111 (4%)
Frame = +3
Query: 39 YSC---DGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSY 209
Y+C GF IC + CL+N C N G C + ++ C C +
Sbjct: 527 YACICKQGFEGDICER------HKDLCLEN-------PCSNGGVCHQHRESFSCDCPPGF 573
Query: 210 IGKLC--EKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRI 356
G C EK G C N +K C CS GF+G +C+ +I
Sbjct: 574 YGNGCEQEKMFRCLKSTCQNGGVCI--NEEEKGRKCECSYGFSGARCEEKI 622
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/138 (28%), Positives = 55/138 (39%), Gaps = 10/138 (7%)
Frame = +3
Query: 18 CFPIENEYSCDGFGNKIC---REGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLT-- 182
C N Y CD C R G Y + + + C N+G CI++ L+
Sbjct: 302 CINGVNSYFCD------CPPERTGPYCEKMDCSAIPDIC--------NHGTCIDSPLSEK 347
Query: 183 -YECKCLDSYIGKLCE--KXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCD-- 347
+EC+C Y G LCE K G C V G + C C+ GF G+ CD
Sbjct: 348 AFECQCEPGYEGILCEQDKNECLSENMCLNNGTC-VNLPGS--FRCDCARGFGGKWCDEP 404
Query: 348 LRIYQPCICPKNMKCNYS 401
L + Q C + C ++
Sbjct: 405 LNMCQDFHCENDGTCMHT 422
Score = 40.8 bits (94), Expect = 0.004
Identities = 30/116 (25%), Positives = 45/116 (38%), Gaps = 6/116 (5%)
Frame = +3
Query: 99 ESKCLKNNCISSNIQCQNNGYCINNG--LTYECKCLDSYIGKLCEKXXXXXXXXXXXXGK 272
+S +N C+S C NN CI+ + Y C C + G +CE+ G
Sbjct: 499 KSSLSENLCLSD--PCMNNATCIDVDAHIGYACICKQGFEGDICERHKDLCLENPCSNGG 556
Query: 273 CFVQNHGDKLYACSCSEGFTGEKCDLRIYQPCI---CPKNMKC-NYSESGALFSCT 428
Q+ + ++C C GF G C+ C+ C C N E G C+
Sbjct: 557 VCHQHR--ESFSCDCPPGFYGNGCEQEKMFRCLKSTCQNGGVCINEEEKGRKCECS 610
Score = 37.4 bits (85), Expect = 0.049
Identities = 24/100 (24%), Positives = 33/100 (33%)
Frame = +3
Query: 45 CDGFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYECKCLDSYIGKLC 224
CD GN + + C ++ C N G CI G +C C D + G+ C
Sbjct: 91 CDINGNSLLKPSCPSGYGGDDCKTQGWCYPSV-CMNGGQCIGAGNRAKCACPDGFKGERC 149
Query: 225 EKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKC 344
E G + Y C C +GF C
Sbjct: 150 ELDVNECEENKNACGNRSTCMNTLGTYICVCPQGFLPPDC 189
Score = 37.4 bits (85), Expect = 0.049
Identities = 35/144 (24%), Positives = 49/144 (34%), Gaps = 4/144 (2%)
Frame = +3
Query: 15 FCFPIENEYSCD-GFGNKICREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGLTYEC 191
FC ++ C G+ C +E C N C ++G CI+ ++C
Sbjct: 226 FCDKASSKCQCPPGYHGSTCE----LLEKEDSCASNPC--------SHGVCISFSGGFQC 273
Query: 192 KCLDSYIGKLCEKXXXXXXXXXXXXG-KCFVQNHGDKLYACSCSEGFTGEKCDLRIYQ-- 362
C D Y G C++ G KC +G Y C C TG C+
Sbjct: 274 ICDDGYSGSYCQEGKDNCVNNKCEAGSKCI---NGVNSYFCDCPPERTGPYCEKMDCSAI 330
Query: 363 PCICPKNMKCNYSESGALFSCTSE 434
P IC + S F C E
Sbjct: 331 PDICNHGTCIDSPLSEKAFECQCE 354
Score = 37.0 bits (84), Expect = 0.064
Identities = 30/119 (25%), Positives = 44/119 (36%), Gaps = 6/119 (5%)
Frame = +3
Query: 45 CD-GFGNKICREGLYYNAQESKC-LKNNCISSNIQCQNNGYC----INNGLTYECKCLDS 206
CD GFG + C + SKC C+ C IN + C
Sbjct: 51 CDEGFGGEYCEQ----QCDVSKCGADEKCVFDKDYRMETCVCKDCDINGNSLLKPSCPSG 106
Query: 207 YIGKLCEKXXXXXXXXXXXXGKCFVQNHGDKLYACSCSEGFTGEKCDLRIYQPCICPKN 383
Y G C+ G+C + K C+C +GF GE+C+L + + C +N
Sbjct: 107 YGGDDCKTQGWCYPSVCMNGGQCIGAGNRAK---CACPDGFKGERCELDVNE---CEEN 159
Score = 35.4 bits (80), Expect = 0.19
Identities = 32/134 (23%), Positives = 49/134 (36%), Gaps = 22/134 (16%)
Frame = +3
Query: 15 FCFP--IENEYSCDGFGNKI---CREGLYYNAQESKCLKNNCISSNIQCQNNGYCINNGL 179
+C+P N C G GN+ C +G + + + N C + C N C+N
Sbjct: 117 WCYPSVCMNGGQCIGAGNRAKCACPDG--FKGERCELDVNECEENKNACGNRSTCMNTLG 174
Query: 180 TYECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQ---NH--GDKLYA------------ 308
TY C C ++ C K CF++ +H G +Y
Sbjct: 175 TYICVCPQGFLPPDCLKPGNTSTVEFKQP-VCFLEISADHPDGRSMYCQNGGFCDKASSK 233
Query: 309 CSCSEGFTGEKCDL 350
C C G+ G C+L
Sbjct: 234 CQCPPGYHGSTCEL 247
Score = 31.2 bits (69), Expect = 3.5
Identities = 26/114 (22%), Positives = 44/114 (38%), Gaps = 20/114 (17%)
Frame = +3
Query: 144 CQNNGYC----INNGLT-YECKCLDSYIGKLCEKXXXXXXXXXXXXGKCFVQN------- 287
C NG+C +N T Y C+C + + G+ CE+ KC
Sbjct: 29 CGRNGHCHAGPVNGTQTSYWCRCDEGFGGEYCEQQCDVSKCGADE--KCVFDKDYRMETC 86
Query: 288 -------HGDKLYACSCSEGFTGEKCDLRIY-QPCICPKNMKCNYSESGALFSC 425
+G+ L SC G+ G+ C + + P +C +C + + A +C
Sbjct: 87 VCKDCDINGNSLLKPSCPSGYGGDDCKTQGWCYPSVCMNGGQCIGAGNRAKCAC 140
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,542,996
Number of Sequences: 369166
Number of extensions: 1844432
Number of successful extensions: 8355
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5232
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7156
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7715018400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)