Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_002_G04 (806 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8V439|R1AB_CVBLU Replicase polyprotein 1ab (pp1ab) (ORF... 33 0.92 sp|Q91A29|R1AB_CVBEN Replicase polyprotein 1ab (pp1ab) (ORF... 33 1.2 sp|Q66198|R1AB_CVBM Replicase polyprotein 1ab (pp1ab) (ORF1... 33 1.2 sp|Q8V6W7|R1AB_CVBQ Replicase polyprotein 1ab (pp1ab) (ORF1... 33 1.2 sp|Q8BFV3|DUS4_MOUSE Dual specificity protein phosphatase 4 31 3.5 sp|Q13115|DUS4_HUMAN Dual specificity protein phosphatase 4... 31 3.5 sp|Q62767|DUS4_RAT Dual specificity protein phosphatase 4 (... 31 3.5 sp|Q94VC3|NU1M_VARRU NADH-ubiquinone oxidoreductase chain 1... 31 4.6
>sp|Q8V439|R1AB_CVBLU Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Includes: Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains: p28; p65; p210 (Papain-like proteinases 1/2) (PL1-PRO/PL2-PRO); Peptide HD2 (p44); 3C-like proteinase (3CL-PRO) (3CLp) (M-PRO) (p27); Unknown protein 1; p10; p22; p12; Growth factor-like peptide (GFL) (p15); RNA-directed RNA polymerase (RdRp) (Pol) (p100); Helicase (Hel) (p67); Unknown protein 2; p35; Unknown protein 3] Length = 7094 Score = 33.1 bits (74), Expect = 0.92 Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 10/100 (10%) Frame = +1 Query: 151 NFQTNYKSILSSYYVDCVKIIDEIKDCNEKVDYLVNFLQLL---SIYYTQTL----YRDI 309 N + +KS+L++YY+D VK K++Y + Q YYTQ + ++ Sbjct: 1864 NLKQTFKSVLTTYYLDDVK----------KIEYKPDLSQYYCDGGKYYTQRIIKAQFKTF 1913 Query: 310 LAVSXXXXXXKKI-FLICDNRNAAIIYESLK--ITYKLTD 420 V K I ICD NA + ++S K + YK+T+ Sbjct: 1914 EKVDGVYTNFKLIGHTICDILNAKLGFDSSKEFVEYKVTE 1953
>sp|Q91A29|R1AB_CVBEN Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Includes: Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains: p28; p65; p210 (Papain-like proteinases 1/2) (PL1-PRO/PL2-PRO); Peptide HD2 (p44); 3C-like proteinase (3CL-PRO) (3CLp) (M-PRO) (p27); Unknown protein 1; p10; p22; p12; Growth factor-like peptide (GFL) (p15); RNA-directed RNA polymerase (RdRp) (Pol) (p100); Helicase (Hel) (p67); Unknown protein 2; p35; Unknown protein 3] Length = 7094 Score = 32.7 bits (73), Expect = 1.2 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 7/97 (7%) Frame = +1 Query: 151 NFQTNYKSILSSYYVDCVKIIDEIKDCNEKVDYLVNFLQLLSIYYTQTL----YRDILAV 318 N + +KS+L++YY+D VK I+ D ++ Y + YYTQ + ++ V Sbjct: 1864 NLKQTFKSVLTTYYLDDVKKIEYNPDLSQ---YYCDG----GKYYTQRIIKAQFKTFEKV 1916 Query: 319 SXXXXXXKKI-FLICDNRNAAIIYESLK--ITYKLTD 420 K I ICD NA + ++S K + YK+T+ Sbjct: 1917 DGVYTNFKLIGHTICDILNAKLGFDSSKEFVEYKVTE 1953
>sp|Q66198|R1AB_CVBM Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Includes: Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains: p28; p65; p210 (Papain-like proteinases 1/2) (PL1-PRO/PL2-PRO); Peptide HD2 (p44); 3C-like proteinase (3CL-PRO) (3CLp) (M-PRO) (p27); Unknown protein 1; p10; p22; p12; Growth factor-like peptide (GFL) (p15); RNA-directed RNA polymerase (RdRp) (Pol) (p100); Helicase (Hel) (p67); Unknown protein 2; p35; Unknown protein 3] Length = 7094 Score = 32.7 bits (73), Expect = 1.2 Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 10/100 (10%) Frame = +1 Query: 151 NFQTNYKSILSSYYVDCVKIIDEIKDCNEKVDYLVNFLQLL---SIYYTQTL----YRDI 309 N + +KS+L++YY+D VK K++Y + Q YYTQ + ++ Sbjct: 1864 NLKQTFKSVLTTYYLDDVK----------KIEYKPDLSQYYCDGGKYYTQRIIKAQFKTF 1913 Query: 310 LAVSXXXXXXKKI-FLICDNRNAAIIYESLK--ITYKLTD 420 V K I +CD NA + ++S K + YK+T+ Sbjct: 1914 EKVDGVYTNFKLIGHTVCDILNAKLGFDSSKEFVEYKVTE 1953
>sp|Q8V6W7|R1AB_CVBQ Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Includes: Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains: p28; p65; p210 (Papain-like proteinases 1/2) (PL1-PRO/PL2-PRO); Peptide HD2 (p44); 3C-like proteinase (3CL-PRO) (3CLp) (M-PRO) (p27); Unknown protein 1; p10; p22; p12; Growth factor-like peptide (GFL) (p15); RNA-directed RNA polymerase (RdRp) (Pol) (p100); Helicase (Hel) (p67); Unknown protein 2; p35; Unknown protein 3] Length = 7059 Score = 32.7 bits (73), Expect = 1.2 Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 10/100 (10%) Frame = +1 Query: 151 NFQTNYKSILSSYYVDCVKIIDEIKDCNEKVDYLVNFLQLL---SIYYTQTL----YRDI 309 N + +KS+L++YY+D VK K++Y + Q YYTQ + ++ Sbjct: 1864 NLKQTFKSVLTTYYLDDVK----------KIEYKPDLSQYYCDGGKYYTQRIIKAQFKTF 1913 Query: 310 LAVSXXXXXXKKI-FLICDNRNAAIIYESLK--ITYKLTD 420 V K I +CD NA + ++S K + YK+T+ Sbjct: 1914 EKVDGVYTNFKLIGHTVCDILNAKLGFDSSKEFVEYKVTE 1953
>sp|Q8BFV3|DUS4_MOUSE Dual specificity protein phosphatase 4 Length = 398 Score = 31.2 bits (69), Expect = 3.5 Identities = 10/29 (34%), Positives = 22/29 (75%) Frame = +1 Query: 157 QTNYKSILSSYYVDCVKIIDEIKDCNEKV 243 + N+K+ +SS++++ ++ ID +KDC +V Sbjct: 252 EDNHKADISSWFMEAIEYIDAVKDCRGRV 280
>sp|Q13115|DUS4_HUMAN Dual specificity protein phosphatase 4 (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2) Length = 394 Score = 31.2 bits (69), Expect = 3.5 Identities = 10/29 (34%), Positives = 22/29 (75%) Frame = +1 Query: 157 QTNYKSILSSYYVDCVKIIDEIKDCNEKV 243 + N+K+ +SS++++ ++ ID +KDC +V Sbjct: 248 EDNHKADISSWFMEAIEYIDAVKDCRGRV 276
>sp|Q62767|DUS4_RAT Dual specificity protein phosphatase 4 (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) Length = 395 Score = 31.2 bits (69), Expect = 3.5 Identities = 10/29 (34%), Positives = 22/29 (75%) Frame = +1 Query: 157 QTNYKSILSSYYVDCVKIIDEIKDCNEKV 243 + N+K+ +SS++++ ++ ID +KDC +V Sbjct: 249 EDNHKADISSWFMEAIEYIDAVKDCRGRV 277
>sp|Q94VC3|NU1M_VARRU NADH-ubiquinone oxidoreductase chain 1 (NADH dehydrogenase subunit 1) Length = 318 Score = 30.8 bits (68), Expect = 4.6 Identities = 22/69 (31%), Positives = 35/69 (50%) Frame = -1 Query: 680 PIRNQQSSTQLFSIRNVLCLPKARALSSMIPIAISKHSLENVPKNLLTIFSRMIL*RNST 501 PIR +S L + +L L A + + IP+ H+L N+ LL+I + + NST Sbjct: 61 PIRPLNTSPTLLILSPILALTTAMLIWTPIPMP---HALTNLNLGLLSILAISSMAVNST 117 Query: 500 MLAGHTQSS 474 + AG +S Sbjct: 118 LWAGWASNS 126
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 80,695,158 Number of Sequences: 369166 Number of extensions: 1503239 Number of successful extensions: 3627 Number of sequences better than 10.0: 8 Number of HSP's better than 10.0 without gapping: 3522 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3627 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7666799535 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)