Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_G03
(656 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P35074|RPB1_CAEBR DNA-directed RNA polymerase II largest... 36 0.10
sp|P16356|RPB1_CAEEL DNA-directed RNA polymerase II largest... 35 0.22
sp|O15018|PDZK3_HUMAN PDZ domain containing protein 3 (PDZ ... 33 0.65
sp|P35085|CBPA_DICDI Calcium-binding protein 33 0.85
sp|O14686|MLL2_HUMAN Myeloid/lymphoid or mixed-lineage leuk... 32 1.1
sp|P56945|BCA1_HUMAN CRK-associated substrate (p130Cas) (Br... 32 1.1
sp|P35084|RPB1_DICDI DNA-directed RNA polymerase II largest... 32 1.5
sp|Q8SSC4|RPB1_ENCCU DNA-directed RNA polymerase II largest... 32 1.9
sp|P54258|ATN1_RAT Atrophin-1 (Dentatorubral-pallidoluysian... 31 2.5
sp|Q10135|YAR2_SCHPO DNA-binding protein C23E2.02 in chromo... 31 2.5
>sp|P35074|RPB1_CAEBR DNA-directed RNA polymerase II largest subunit
Length = 1853
Score = 35.8 bits (81), Expect = 0.10
Identities = 30/96 (31%), Positives = 36/96 (37%), Gaps = 1/96 (1%)
Frame = +3
Query: 6 TPGPNVYS-VDPMLSRTVRSQKPSAPMISMSSRSKIGGFHEDLQKTPGPGTYKVTDPGVF 182
+P YS P S T P++P S SS + TP TY T P F
Sbjct: 1725 SPSSPTYSPTSPSYSPTSPQYSPTSPQYSPSSPTY----------TPSSPTYNPTSPRAF 1774
Query: 183 KSRYPMYSMTSRNPMPGDTTQKPGPGAYSAELVTFT 290
S P YS TS P + P YS T+T
Sbjct: 1775 SS--PQYSPTSPTYSPTSPSYTPSSPQYSPTSPTYT 1808
Score = 34.7 bits (78), Expect = 0.22
Identities = 24/85 (28%), Positives = 32/85 (37%)
Frame = +3
Query: 15 PNVYSVDPMLSRTVRSQKPSAPMISMSSRSKIGGFHEDLQKTPGPGTYKVTDPGVFKSRY 194
P P S T + P++P S +S S G + +P TY T P +
Sbjct: 1684 PTYSPTSPTYSPTSPTYSPTSPTYSPTSPSYEGYSPSSPKYSPSSPTYSPTSPS-YSPTS 1742
Query: 195 PMYSMTSRNPMPGDTTQKPGPGAYS 269
P YS TS P T P Y+
Sbjct: 1743 PQYSPTSPQYSPSSPTYTPSSPTYN 1767
>sp|P16356|RPB1_CAEEL DNA-directed RNA polymerase II largest subunit
Length = 1852
Score = 34.7 bits (78), Expect = 0.22
Identities = 30/96 (31%), Positives = 36/96 (37%), Gaps = 1/96 (1%)
Frame = +3
Query: 6 TPGPNVYS-VDPMLSRTVRSQKPSAPMISMSSRSKIGGFHEDLQKTPGPGTYKVTDPGVF 182
+P YS P S T P++P S SS + TP TY T P F
Sbjct: 1724 SPSSPTYSPTSPSYSPTSPQYSPTSPQYSPSSPTY----------TPSSPTYNPTSPRGF 1773
Query: 183 KSRYPMYSMTSRNPMPGDTTQKPGPGAYSAELVTFT 290
S P YS TS P + P YS T+T
Sbjct: 1774 SS--PQYSPTSPTYSPTSPSYTPSSPQYSPTSPTYT 1807
>sp|O15018|PDZK3_HUMAN PDZ domain containing protein 3 (PDZ domain containing protein 2)
(Activated in prostate cancer protein)
Length = 2839
Score = 33.1 bits (74), Expect = 0.65
Identities = 28/101 (27%), Positives = 41/101 (40%), Gaps = 2/101 (1%)
Frame = +3
Query: 9 PGPNVYSVDP-MLSRTVRSQKPSAPMISM-SSRSKIGGFHEDLQKTPGPGTYKVTDPGVF 182
P P+ SVD +SR +P++P ++ +RS + HE +P PG P
Sbjct: 1247 PDPSKTSVDTGQVSRPENPSQPASPRVAKCKARSPVRLPHEG---SPSPGEKAAAPPDYS 1303
Query: 183 KSRYPMYSMTSRNPMPGDTTQKPGPGAYSAELVTFTRPGAP 305
K+R + T N + GPGA PG P
Sbjct: 1304 KTRSASETSTPHNTRRVAALRGAGPGAEGMTPAGAVLPGDP 1344
>sp|P35085|CBPA_DICDI Calcium-binding protein
Length = 467
Score = 32.7 bits (73), Expect = 0.85
Identities = 24/64 (37%), Positives = 27/64 (42%), Gaps = 6/64 (9%)
Frame = +3
Query: 132 QKTPG----PGTYKVTDPGVFKSRYPMYSMTSRNPMPGDTTQKP--GPGAYSAELVTFTR 293
Q TPG PG Y PG S P Y T + PG Q P PG Y + +
Sbjct: 34 QSTPGAPGAPGQYPPQQPGAPGSNLPPYPGTQQPGAPGAPGQYPPQQPGQYPPQ-----Q 88
Query: 294 PGAP 305
PGAP
Sbjct: 89 PGAP 92
>sp|O14686|MLL2_HUMAN Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related
protein)
Length = 5262
Score = 32.3 bits (72), Expect = 1.1
Identities = 31/134 (23%), Positives = 49/134 (36%), Gaps = 23/134 (17%)
Frame = +3
Query: 12 GPNVYSVDPMLSRTVRSQKPSAPMISMSSRSKIGGFHEDLQKTPGPGTYKVTDPG----- 176
GP + D LSR PS+ + ++SR +GG Q+ P PG+ +
Sbjct: 2487 GPGSFPSDDRLSRPPPPATPSS--MDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQ 2544
Query: 177 ------------VFKSRYP------MYSMTSRNPMPGDTTQKPGPGAYSAELVTFTRPGA 302
+R+P + +P+ G +T+ PGPG P
Sbjct: 2545 QQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGE------PVPGPAG 2598
Query: 303 PKFTFGIRHSQYKG 344
P +RH+ KG
Sbjct: 2599 PAQFIELRHNVQKG 2612
>sp|P56945|BCA1_HUMAN CRK-associated substrate (p130Cas) (Breast cancer anti-estrogen
resistance 1 protein)
Length = 870
Score = 32.3 bits (72), Expect = 1.1
Identities = 24/94 (25%), Positives = 36/94 (38%), Gaps = 4/94 (4%)
Frame = +3
Query: 9 PGPNVYSVDPMLSRTVRSQKPSAPMISMSSRSKIGGFHEDLQKTPGPGTYKVTDPGVFKS 188
P P PML T + Q S ++ S+++ G L + PGP + P K
Sbjct: 92 PAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG-----LYQVPGPSPQFQSPPA--KQ 144
Query: 189 RYPMYSMTSRNPMPGDTTQ----KPGPGAYSAEL 278
T +P P T PGPG + ++
Sbjct: 145 TSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDI 178
>sp|P35084|RPB1_DICDI DNA-directed RNA polymerase II largest subunit
Length = 902
Score = 32.0 bits (71), Expect = 1.5
Identities = 25/92 (27%), Positives = 36/92 (39%)
Frame = +3
Query: 15 PNVYSVDPMLSRTVRSQKPSAPMISMSSRSKIGGFHEDLQKTPGPGTYKVTDPGVFKSRY 194
P+ P S T S P++P S +S S +P +Y T P +
Sbjct: 810 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY----------SPTSPSYSPTSPS-YSPTS 858
Query: 195 PMYSMTSRNPMPGDTTQKPGPGAYSAELVTFT 290
P YS +S + P + P +YS TFT
Sbjct: 859 PSYSPSSPSYSPSSPSYSPSSPSYSPSSPTFT 890
>sp|Q8SSC4|RPB1_ENCCU DNA-directed RNA polymerase II largest subunit (RNA polymerase II
subunit 1)
Length = 1599
Score = 31.6 bits (70), Expect = 1.9
Identities = 25/98 (25%), Positives = 38/98 (38%)
Frame = +3
Query: 15 PNVYSVDPMLSRTVRSQKPSAPMISMSSRSKIGGFHEDLQKTPGPGTYKVTDPGVFKSRY 194
P+ P S T S P++P S +S S +P +Y T P +
Sbjct: 1499 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY----------SPTSPSYSPTSPS-YSPTS 1547
Query: 195 PMYSMTSRNPMPGDTTQKPGPGAYSAELVTFTRPGAPK 308
P YS TS + P + P +YS + +F+ K
Sbjct: 1548 PSYSPTSPSYSPTSPSYSPTSPSYSVSMSSFSNKNKSK 1585
>sp|P54258|ATN1_RAT Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein)
Length = 1183
Score = 31.2 bits (69), Expect = 2.5
Identities = 17/58 (29%), Positives = 25/58 (43%)
Frame = +3
Query: 132 QKTPGPGTYKVTDPGVFKSRYPMYSMTSRNPMPGDTTQKPGPGAYSAELVTFTRPGAP 305
++ P PG+YK P +K P T P T+ GPG + +PG+P
Sbjct: 634 KRAPSPGSYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTF--------KPGSP 683
>sp|Q10135|YAR2_SCHPO DNA-binding protein C23E2.02 in chromosome I
Length = 1273
Score = 31.2 bits (69), Expect = 2.5
Identities = 14/39 (35%), Positives = 28/39 (71%)
Frame = -1
Query: 470 SNETNKHAIEITNQTHHIPSLLIIGYSFIFSYLINIVVN 354
SN T+ + ++T+ +H IPS + +G+ F+FS + +I++N
Sbjct: 586 SNSTSLNPKDVTDPSH-IPSAIDLGFQFLFSPMDDILLN 623
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,344,376
Number of Sequences: 369166
Number of extensions: 1851069
Number of successful extensions: 5012
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4781
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4987
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5462583840
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)